Visible Continuum Source for Fluorescence Excitation

Information

  • Research Project
  • 6833603
  • ApplicationId
    6833603
  • Core Project Number
    R43EB003326
  • Full Project Number
    1R43EB003326-01A1
  • Serial Number
    3326
  • FOA Number
  • Sub Project Id
  • Project Start Date
    9/24/2004 - 20 years ago
  • Project End Date
    5/31/2005 - 19 years ago
  • Program Officer Name
    LEWIS, CATHERINE D.
  • Budget Start Date
    9/24/2004 - 20 years ago
  • Budget End Date
    5/31/2005 - 19 years ago
  • Fiscal Year
    2004
  • Support Year
    1
  • Suffix
    A1
  • Award Notice Date
    9/24/2004 - 20 years ago

Visible Continuum Source for Fluorescence Excitation

DESCRIPTION (provided by applicant): We propose to develop a light source having a spectrum that spans the visible wavelengths, with a beam quality similar to a laser. Our goal is to cover the wavelengths from 400 nm- 700 nm, with at least 1 mW in any 1 nm slice of the spectrum. The light source will be based on an inexpensive diode-pumped mode-locked laser, the output of which is spectrally broadened into a continuum by a highly nonlinear, single-mode, fused-silica fiber. The output of the fiber will be pulses of diffraction-limited white light, with a pulse repetition rate near 100 MHz. Such a high repetition rate is equivalent to continuous light for virtually all instrument applications. Such a source would have many laboratory uses, for example in fluorescence imaging. The spectrum of the proposed source could be filtered to obtain a laser-like beam at any desired visible wavelength. This flexibility would make fluorescence confocal microscopes much more powerful tools, since they could be used at any excitation wavelength.

IC Name
NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING
  • Activity
    R43
  • Administering IC
    EB
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    81354
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    866
  • Ed Inst. Type
  • Funding ICs
    NIA:81353\NIBIB:1\
  • Funding Mechanism
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    LIGHTWAVE ELECTRONICS CORPORATION
  • Organization Department
  • Organization DUNS
  • Organization City
    MOUNTAIN VIEW
  • Organization State
    CA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    94043
  • Organization District
    UNITED STATES