The invention relates to a vital signs monitoring system as well as a method of monitoring vital signs of a user.
Optical heart rate sensors are well known to monitor or detect vital signs like a heart rate of a user. Such a heart rate sensor can be based on a photoplethysmographic (PPG) sensor and can be used to acquire a volumetric organ measurement. By means of pulse oximeters, changes in light absorption of a human skin is detected and based on these measurements a heart rate or other vital signs of a user can be determined. The PPG sensors comprise a light source like a light emitting diode (LED) which is emitting light into the skin of a user. The emitted light is scattered in the skin and is at least partially absorbed by the blood. Part of the light exits the skin and can be captured by a photodiode. The amount of light that is captured by the photodiode can be an indication of the blood volume inside the skin of a user. A PPG sensor can monitor the perfusion of blood in the dermis and subcutaneous tissue of the skin through an absorption measurement at a specific wavelength. If the blood volume is changed due to the pulsating heart, the scattered light coming back from the skin of the user is also changing. Therefore, by monitoring the detected light signal by means of the photodiode, a pulse of a user in his skin and thus the heart rate can be determined.
US 2007/287927 discloses a vital signs measurement device with an optical sensing system. The optical sensing system comprises an optical source producing a speckle pattern output and an optical detector to detect at least part of the speckle pattern. The optical source is a coherent light source like a laser. Alternatively, an LED can be used.
It is an object of the invention to provide a vital signs monitoring system, which is able to efficiently detect a heart rate of a user as well as additional vital sign information.
In an aspect of the present invention, a vital sign monitoring system is provided. The vital sign monitoring system comprises at least one optical vital signs sensor configured to measure or determine vital signs of the user and to output an output signal. The optical vital signs sensor comprises at least one laser light source configured to generate laser light, which is directed towards a skin of a user. The optical vital signs sensor furthermore comprises at least one photo detector unit configured to detect light which is indicative of an absorption or reflection of the laser light from the at least one light source in or from the skin of the user. The vital signs monitoring system furthermore comprises a coherence distortion unit. In a first operational mode the coherence distortion unit is configured to distort a wave front from laser light from the at least one laser light source such that the coherence of the light that is directed towards the skin of a user is distorted. In a second operational mode the coherence distortion unit is configured to deactivate the distortion of the wave front of the laser light such that coherent light is directed undistorted towards the skin of the user. Accordingly, by means of the coherent distortion unit a single light source in the form of a laser light source can be used and the light entering the skin of the user can have two different modes, namely coherent or non-coherent. The vital signs monitoring system comprises an analyzing unit with a heart rate analyzing unit and a microcirculation analyzing unit. In the first operational mode the heart rate analyzing unit is configured to analyze the output of the at least one photo detector to determine the heart rate of a user. In a second operational mode the microcirculation analyzing unit is configured to analyze the output of the at least one photo detector to determine parameters of microcirculation. Hence, in a first operational mode the heart rate of a user can be detected and in second operational modes parameters of the microcirculation can be detected.
According to an aspect of the invention the at least one optical vital signs sensor is a photoplethysmographic PPG sensor.
In a further aspect of the invention, the vital signs monitoring system comprises a control unit for activating the first or second operational mode.
In a further aspect of the present invention, the coherence distortion is configured to control an input current supply to the at least one light source in order to change the emitting mode of the laser light source to distort the wave front of the laser light from the at least one laser light source in the first operational mode.
According to a further aspect of the invention, the coherence distortion unit comprises a phase plate or phase diffuser configured to spatially distort a phase of the wave front of the laser light from the at least one laser light source.
According to a further aspect of the invention, the coherence distortion unit comprises an electrically control diffuser to spatially distort a phase of the wave front of the laser light from the at least one laser light source.
According to a further aspect of the invention, the coherence distortion unit comprises a phase modulator to distort a phase of the wave front of the laser light from the at least one laser light source. Examples of such phase modulators are electro-optical EO modulators comprising a non-linear chrystal, acousto-optical (AO) modulators and (rotating) phase plates.
In a further aspect of the invention, the coherence distortion unit comprises a spatial light modulator to spatially distort a phase of the wave front of the laser light from the at least one laser light source i.e. by changing the diffusivity. Examples of such spatial light modulators are liquid crystal (LC) modulators, electro-chromic modulators and mechanical modulators like rotation wheels, scanning systems, or piezo- or galvano scanners.
In a further aspect of the invention, the coherence distortion unit comprises a wavelength modulator configured to change the wavelength of the light thereby distorting the wave front. Such modulators can be an etalon or Fabry-Pérot interferometer or an electro-optical modulator.
According to an aspect of the invention, the coherence distortion unit can be implemented as an optically addressed modulator (like a liquid crystal modulator, an electro-chromic modulator, an electro optical modulator, an acousto-optical modulator), as an electrically addressed modulator (like a rotating diffuser, a rotating phase plate, a galvanic or piezoelectric device) or as a wavelength modulator.
According to an aspect of the invention it was realized that the typically unwanted high frequency noise in the output of a PPG sensor (when using a laser light source) can be used to advantage if it can be discarded for the detection of the heart rate while being used to obtain information on the microcirculation of the user. Hence, speckle analysis can be used according to an aspect of the invention to detect microcirculation.
According to a further aspect of the invention, the at least one laser light source comprises a stepped ultra-thin cavity solid state laser.
It shall be understood that a preferred embodiment of the present invention can also be a combination of the dependent claims or above embodiments or aspects with respective independent claims.
These and other aspects of the invention will be apparent from and elucidated with reference to the embodiment(s) described hereinafter.
In the following drawings:
According to the invention, the light source 110 can be implemented as a laser light source. When the heart of a user pulsates, this results in a changing blood volume in the skin of the user which can be detected by the photo detector 120. According to the invention, the laser light source 110 can be operated in a first and second operational mode. In first operational mode, a coherence disturbance unit can be activated in order to disturb or distort a wave front of the output signal of the laser light source. In a second operational mode, the coherence distortion unit can be deactivated such that the laser light source is able to emit coherent light. In the first operational mode, the operational mode only non-coherent light is emitted onto or into the skin of the user.
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The vital sign monitoring system 10 furthermore comprises a coherence distortion unit 200 and optionally a control unit 300. The output of the at least one photo detector 120 can be analyzed in an analyzing unit 400.
Optionally, secondary sensors 500 like accelerometers and an optionally battery unit 600 can be provided. The sensors from the secondary sensor unit 500 can be used to verify or improve the detection or determinations of vital signs.
According to an aspect of the invention the vital sign monitoring system 10 can be embodied as a wrist device for example a smart watch. In this case, the device may also comprise a battery unit 600.
The vital sign monitoring system 10 can be operated in a first and second operating mode. The control unit 300 is able to switch the vital sign monitoring system between at least first and second operating mode. In the first operating mode, the coherence distortion unit 200 is activated such that substantially non-coherent light reaches the skin 1000 of the user. By means of the coherence disturbing unit 200 the wave front of the laser light can be distorted to achieve a better signal. With the distorted and non-coherent light it is a lot easier to detect a heart rate of a user than with coherent light. Thus, by means of the coherence distortion unit 200 the wave front of the laser light is distorted in order to achieve a better signal for heart rate detection.
According an aspect of the invention, coherence disturbance unit 200 is adapted to control the electric current, which is supplied to the at least one laser light source 110. As the wavelength of emission of a semiconductor laser diode is dependent on its laser current (is e.g. used in Wavelength Modulation Spectroscopy), changes in the laser drive current will change the emitted mode. If the changes of the emitting mode occurs rapidly with frequencies of more than ten kHz the speckle pattern change can occur at a similar rate. In order to change the speckle pattern the average optical path length through the scattering medium and the average optical wavelength need to be change into achieve change of the typical wavelength. For a wavelength of 850 nm and an optical path length of approximately 5 nm, the required wavelength change is equal or larger than 70 picometer.
According to a further aspect of the invention the coherence disturbance unit 200 can be implemented by a phase plate or diffuser, which is arrange in front of the laser light source 110. The phase plate or the diffuser can revolve or rotate such that the wave front will change accordingly. For a frequency larger than several kHz, the speckle pattern will change accordingly. Hence, the phase of the wavelength can be spatially distorted by an electrical-optical cell such as a spatial light modulator.
According to a further aspect of the invention the coherence disturbance unit 200 can be implemented as an electrically controlled diffuser.
According to a further aspect of the invention, the laser light source and the coherence disturbance unit can together be implemented as a vertical-cavity surface emitting laser (VCSEL).
In particular the vertical-cavity surface emitting laser can have a stepped design in the cavity as shown in
Based on the non-coherent light as well as the detected reflections, the vital signs monitoring unit can determine the heart rate of a user when operating in a first operation mode.
In a second operational mode, the coherence disturbance unit 200 is deactivated and coherent light from the laser light source enters the skin of the user. The reflected signal as detected by the photodiode 120 can be used in order to analyze microcirculation of the blood knowledge on the microcirculation in the advantageous hypertension, heart failure, hypercholesterolmea, Alzheimer disease, carpal tunnel syndrome, schizophrenia, renal type 2 diabetes, peripheral vascular disease, atherosclerotic coronary disease, systematic scleroses, obesity, primary aging, sleep apnea, wound assessment, plastic surgery, Doppler cuff blood pressure, peripheral arterial occlusive disease and edema.
According to a further aspect of the invention the coherence disturbance unit 200 can be implemented as an electro-chromic device for disturbing the wave front of the laser by changing the diffusivity of the laser light.
In an aspect of the invention the coherence distortion unit can be implemented as a phase modulator to distort the phase of the wave front. The phase modulator can be an electro-optical (EO) modulator, an AO modulator, rotating phase plate, or alternatively galvanic or piezoelectric steered devices.
Other variations of the disclosed embodiment can be understood and effected by those skilled in the art in practicing the claimed invention from a study of the drawings, the disclosure and the appended claims. In the claims, the word “comprising” does not exclude other elements or steps and in the indefinite article “a” or “an” does not exclude a plurality.
A single unit or device may fulfill the functions of several items recited in the claims. The mere fact that certain measures are recited in mutual different dependent claims does not indicate that a combination of these measurements cannot be used to advantage. A computer program may be stored/distributed on a suitable medium such as an optical storage medium or a solid state medium, supplied together with or as a part of other hardware, but may also be distributed in other forms such as via the internet or other wired or wireless telecommunication systems.
Any reference signs in the claims should not be construed as limiting the scope.
Number | Date | Country | Kind |
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14184098.3 | Sep 2014 | EP | regional |
Filing Document | Filing Date | Country | Kind |
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PCT/EP2015/070415 | 9/8/2015 | WO | 00 |