This application relates generally to voltage regulator circuitry. More specifically, it relates to Implantable Medical Devices (IMDs), and use of voltage regulator circuitry to power a boosting circuit for creating a compliance voltage that powers stimulation circuitry.
Implantable neurostimulator devices are devices that generate and deliver electrical stimuli to body nerves and tissues for the therapy of various biological disorders, such as pacemakers to treat cardiac arrhythmia, defibrillators to treat cardiac fibrillation, cochlear stimulators to treat deafness, retinal stimulators to treat blindness, muscle stimulators to produce coordinated limb movement, peripheral nerve stimulators, spinal cord stimulators (SCS) to treat chronic pain, cortical and deep brain stimulators (DBS) to treat motor and psychological disorders, and other neural stimulators to treat urinary incontinence, sleep apnea, shoulder subluxation, etc.
A stimulator system typically includes an Implantable Pulse Generator (IPG) 10 shown in
In the illustrated IPG 10, there are thirty-two electrodes (E1-E32), split between four percutaneous leads 15, or contained on a single paddle lead 19, and thus the header 23 may include a 2x2 array of eight-electrode lead connectors 22. However, the type and number of leads, and the number of electrodes, in an IPG is application specific and therefore can vary. The conductive case 12, or some conductive portion of the case, can also comprise an electrode (Ec). In an SCS application, the electrode lead(s) are typically implanted in the spinal column proximate to the dura in a patient’s spinal cord, preferably spanning left and right of the patient’s spinal column. The proximal contacts 21 are tunneled through the patient’s tissue to a distant location such as the buttocks where the IPG case 12 is implanted, at which point they are coupled to the lead connectors 22. In a DBS application, the electrode leads are implanted in the brain through holes in the skull, and lead extension are used to connect the leads to the IPG which is typically implanted under the clavicle (collarbone). In other IPG examples designed for implantation directly at a site requiring stimulation, the IPG can be lead-less, having electrodes 16 instead appearing on the body of the IPG 10 for contacting the patient’s tissue. The IPG lead(s) can be integrated with and permanently connected to the IPG 10 in other solutions. SCS therapy can relieve symptoms such as chronic back pain, while DBS therapy can alleviate Parkinsonian symptoms such as tremor and rigidity.
IPG 10 can include an antenna 27a allowing it to communicate bi-directionally with a number of external devices. Antenna 27a as shown comprises a conductive coil within the case 12, although the coil antenna 27a can also appear in the header 23. When antenna 27a is configured as a coil, communication with external devices preferably occurs using near-field magnetic induction. IPG 10 may also include a Radio-Frequency (RF) antenna 27b. In
Stimulation in IPG 10 is typically provided by pulses each of which may include a number of phases (30i), as shown in the example of
In the example of
IPG 10 as mentioned includes stimulation circuitry 28 to form prescribed stimulation at a patient’s tissue. Stimulation circuitry 28 may also be include in an External Trial Stimulator (ETS; not shown), which can be used externally to provide stimulation during a trial phase and prior to implantation of an IPG, as explained in USP 9,259,574, which is incorporated herein by reference. (IPG as used herein should be understood as including an ETS).
Each electrode node ei 39 is connected to an electrode Ei 16 via a DC-blocking capacitor Ci 38, which act as a safety measure to prevent DC current injection into the patient, as could occur for example if there is a circuit fault in the stimulation circuitry 28. Because these DC blocking capacitors can charge during, biphasic pulses can be used, with each pulse comprising a first phase 30a followed thereafter by a second phase 30b of opposite polarity, as shown in
Proper control of the PDACs and NDACs allows any of the electrodes 16 (including the case electrode Ec 12) to be selected to act as anodes or cathodes to create a current through a patient’s tissue, R, hopefully with good therapeutic effect. Consistent with the example provided in
Other stimulation circuitries 28 can also be used in the IPG 10. In an example not shown, a switching matrix can intervene between the one or more PDACs and the electrode nodes ei 39, and between the one or more NDACs and the electrode nodes. Switching matrices allows one or more of the PDACs or one or more of the NDACs to be connected to one or more anode electrode nodes at a given time, and to allow any PDAC or NDAC to be connected to any of the electrode nodes. Various examples of stimulation circuitries can be found in USPs 6,181,969, 8,606,362, 8,620,436, 11,040,192, and 10,912,942. Much of the stimulation circuitry 28 of
Power for the stimulation circuitry 28 is provided by a compliance voltage VH, as described in further detail in U.S. Pat. Application Publications 2013/0289665 and 2018/0071520. The compliance voltage VH may be coupled to the source circuitry (e.g., the PDAC(s)), while ground may be coupled to the sink circuitry (e.g., the NDAC(s)), such that the stimulation circuitry 28 is powered by VH and ground. Other power supply voltages may be used with the PDACs and NDACs, and explained in the '520 Publication, but these aren’t shown in
Preferably, the compliance voltage VH can be produced by a boosting circuit 53. Boosting circuit 53 can comprise an inductor-based boost converter or a capacitor-based charge pump, as explained in USP 11,040,202. The boosting circuit 53 can vary the value of VH based on measurements taken from the stimulation circuitry 28. As explained in detail in the '202 patent, VH measurement circuitry 51 can be used to deduce the voltage drops across the active DACs (e.g., PDAC1 (Vp1) and NDAC2 (Vn2) in the example shown in
Circuitry is disclosed for providing a regulated output voltage from a first voltage, which mat comprise: an output branch comprising at least one output transistor coupled to the first voltage and outputting the regulated output voltage, wherein the at least one output transistor passes an output current; a first branch and a second branch each comprising at least one control transistor coupled to the first voltage; first feedback circuitry configured to set a first current in the first branch, wherein the first current comprises the output current scaled by a scalar; current mirror circuitry configured to mirror the first current as a second current in the second branch; filter circuitry configured to filter transients from the second current compared to first current; and second feedback circuitry configured to drive the at least one output transistor and the at least one control transistors in the first and second branches, wherein the second feedback circuitry comprises a first input coupled to a reference voltage and a second input coupled to the second branch.
In one example, the circuitry may further comprise one or more loads powered by the output voltage and configured to draw a load current from the output voltage. In one example, at least one of the loads comprises a boosting circuit for producing a power supply voltage from the output voltage. In one example, the circuitry further comprising stimulation circuitry in a stimulator device, wherein the power supply voltage is configured to power the stimulation circuitry. In one example, the circuitry further comprises a current source configured to draw a bias current from the output voltage. In one example, the output current comprises a sum of the bias current and the load current. In one example, the first feedback circuitry comprises a first input connected to the output voltage, and a second input connected to an output of the control transistor in the first branch. In one example, the first branch comprises a feedback transistor, wherein an output of the first feedback circuitry controls the feedback transistor. In one example, the current mirror circuitry comprises current mirror transistors in the first and second branches having a common gate connected to the first branch. In one example, the filter circuitry is connected to the common gate connection. In one example, the scalar is set by an effective width of the at least one output transistor relative to a width of the control transistors. In one example, the at least one output transistor comprises a plurality of transistors connected in parallel. In one example, the first voltage is provided by a battery. In one example, the output voltage comprises a function of the reference voltage. In one example, the circuitry further comprises a first resistance and a second resistance, wherein the output voltage comprises a function of the reference voltage, the first resistance and the second resistance. In one example, the output voltage equals the reference voltage. In one example, the first and second feedback circuitries each comprise at least one amplifier.
A method is disclosed for providing a regulated output voltage from a first voltage, which may comprise: outputting from at least one output transistor coupled to the first voltage the regulated output voltage, wherein the at least one output transistor passes an output current; producing a filtered current in a filter branch comprising at least one control transistor coupled to the first voltage, wherein the filtered current comprises a scaled and filtered version of the output current, wherein the filter branch comprises a filtered voltage; and using the filtered voltage to control the at least one output transistor and the at least one control transistor.
In one example, producing the filtered current comprises: producing a sampled current in a sample branch comprising at least one control transistor coupled to the first voltage; mirroring the sampled current to the filtered branch; and filtering transients from the filtered current compared to sampled current. In one example, the filtered voltage is used to control the at least one output transistor and the at least one control transistor in the filter and sample branches. In one example, using the filtered voltage to control the at least one output transistor and the at least one control transistor comprises inputting the filtered voltage to a first input feedback circuitry, wherein an output of the feedback circuitry controls the at least one output transistor and the at least one control transistor. In one example, a reference voltage is input to a second input of the feedback circuitry. In one example, the output voltage comprises a function of the reference voltage. In one example, the output voltage comprises a function of the reference voltage, a first resistance and a second resistance. In one example, the output voltage equals the reference voltage. In one example, the method further comprises powering one or more loads using the output voltage, wherein the one or more loads draw a load current from the output voltage. In one example, at least one of the loads comprises a boosting circuit. In one example, the method further comprises producing a power supply voltage from the output voltage using the boosting circuit. In one example, the power supply voltage is used to power stimulation circuitry in a stimulator device. In one example, the method further comprises drawing a bias current from the output voltage. In one example, the output current comprises a sum of the bias current and the load current. In one example, the filtered current is scaled by setting an effective width of the at least one output transistor relative to an effective width of the at least one control transistor. In one example, the at least one output transistor comprises a plurality of transistors connected in parallel. In one example, the first voltage is provided by a battery.
Because Vbat can vary, Vbat can be regulated before being used to generate other power supplies or other useful voltages in the IPG 10. For example, a master voltage regulator 56 can be used to generate a regulated voltage, Vout, from Vbat. Ideally, Vout comprises a constant voltage that is unaffected by the various loads it powers in the IPG 10, but this is not always the case as explained further below. The value of Vout may be controlled by a reference voltage, Vref, provided by a Vref generator 70. Vref (and hence Vout) may be temperature invariant, and in this regard Vref generator 70 may comprise a band gap generator for example. The value of Vref provided by Vref generator 70 may be adjusted in accordance with control signals (trim), as is known in the art. Use of master regulator 56 is preferable to provide isolation between the battery 14 (Vbat) and the various loads in the IPG 10.
Master regulator 56 can comprise any number of known circuits to generate a constant value of Vout from Vbat.
Vout may be further regulated before it used by other downstream circuits. For example, a first regulator 58 can be used to generate a power supply voltage Vdd from Vout for powering digital circuitry 60 operating within the IPG 100. Vdd may comprise 1.8V in one example. A second regulator 62 can be used to generate a power supply voltage Vaa from Vout for powering analog circuitry 64 operating within the IPG 100. Vaa may comprise 3.3V in one example. See, e.g., USP 9,037,241, which is incorporated by reference in its entirety, describing various analog 64 and digital 60 circuits within an IPG 10. Regulators 58 and 62 can comprise well-known Low Drop Out (LDO) regulators and the like, and the IPG 10 may include still other regulators and power supply voltages not shown in
A charge pump may include one more capacitors 66 and a number of switches 68, 70 that are opened and closed in accordance with interleaved clock signals (e.g., CLK1 and CLK2). A complicated charge pump design capable of producing a multitude of values for the compliance voltage VH is disclosed in Int’l (PCT) Patent Application Publication WO 2021/046120, which is incorporated herein by reference. However,
The charge pump in
The effect of the current transient during the charging phase (CLK1) is made worse because in the intervening boosting phases (CLK2), the current drawn by the charge pump 53 from the master regulator 56 is essentially zero. This makes the sudden current transients during the charging phases (CLK1) that much more difficult for the master regulator 56 to quickly handle.
In short, downstream circuitry such as the boosting circuit 53 can destabilize the output Vout of the master regulator 56. This creates problems both for operation of the boosting circuit 53, as well as for other regulators such as 58 and 62 to which Vout is input. Said simply, if Vout is not well regulated and varies from its optimal value, downstream voltages such as VH, Vdd, and Vaa may also not be well regulated and may also vary, thus affecting operation of circuits (28, 60, and 64) that those downstream voltages power.
The inventors have therefore devised an improved regulator circuit 100, which is able to handle output current transients while still maintaining Vout at a more-constant level. The improved regulator circuit 100 is preferably used for the master regulator 56 in
Vref is provided to the negative input of diff amp 102, similarly tpo what occurred in the master regulator 56 of
The output of diff amp 102 is connected to the gates of M2, M1, and at least one output transistor M0 in an output branch 124 responsible for producing Vout and Iout at its drain. The sources of M2, M1, and M0 are connected to the power supply, such as Vbat, although again another power supply voltage could be used as well. Preferably, M0 is scaled in size with respect to transistors M1 and M2 in a known manner, and such scaling can be affected in a number of different ways. For example, M0 may comprise a single transistor whose width is 1000 times larger than the widths of transistors M1 and M2. Alternatively, M0 can comprise 1000 transistors similar in size to those used for M1 and M2, but wired in parallel (which is essentially equivalent to a single wider transistor). A scalar of 1000 is chosen in this example, but a different value for the scalar could also be set (including 1).
This scaling helps to set the value of the currents in branches 122 and 120. First, note that Vout at the drain of M0 is provided to the positive input of a diff amp 104. Diff amp 104's output is connected to the gate of transistor M5 in branch 122, which together comprise feedback circuitry, although such feedback can be achieved in other ways. The negative input of diff amp 104 is connected to the drain of transistor M1 in branch 122. Feedback causes Vout present at the positive input to be reflected at the negative input connected to the drain of transistor M1. As such, the drain-to-source voltage drop is held the same (Vbat-Vout) across M1 and M0. Because of this, and because M1 and M0 are controlled equally by their common gate connection, the current formed in branch 122, Isamp, will scale in accordance with the difference in the effective widths between M0 and M1. The current flowing through M0 comprises Iout, which equals Iload drawn by downstream circuitry (e.g., charge pump 53, etc.), plus Ibias provided by a current source 108. (Ibias and current source 108 are discussed further below). The current Isamp in branch 122 is therefore set to one one-thousandth of this value. In other words, Isamp = 0.001(Iload+Ibais), and is so named because it comprises a scaled-down sample of Iout. Illustration of Iout and Isamp are shown in
As explained above, Ifilt in branch 120 is generally formed (by virtue of the current mirror transistors M3 and M4) as a mirrored version of Isamp in branch 122, although it is filtered by a low pass filter 106. This low pass filter 106 in one example comprises a serial connection of a resistor R and capacitor C, which is connected between the common-gate connection of M3/M4 and ground. The low pass filter 106 smooths transients in Isamp (resulting from the transients in Iload and therefore Iout) and in particular smooths the voltage on the common-gate connection of M3/M4. As a result, Ifilt in branch 120 varies more slowly than Isamp in branch 122, as shown in
Ifilt causes Vfilt to be formed at the node between transistors M2 and M4 in branch 120. Vfilt, as shown in
Referring again to
In
Although particular embodiments of the present invention have been shown and described, the above discussion is not intended to limit the present invention to these embodiments. It will be obvious to those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the present invention. Thus, the present invention is intended to cover alternatives, modifications, and equivalents that may fall within the spirit and scope of the present invention as defined by the claims.
This is a non-provisional application of U.S. Provisional Pat. Application Serial No. 63/262,173, filed Oct. 6, 2021, to which priority is claimed, and which is incorporated herein by reference in its entirety.
Number | Date | Country | |
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63262173 | Oct 2021 | US |