Burger, Ed. "Medicinal Chemistry" 2d Ed. Interscience, NY, 1960 p. 42. |
Wall et al., "Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin . . . " JACS, 88/16 (Aug. 20, 1966) 3888-3890. |
Liu, "DNA Topoisomerases-Enzymes . . . , " CRC Critical Review in Biochem., 15, 1-24 (1983). |
Vosberg, "DNA Topoisomerases: Enzymes taht . . . , " Current Topics in Microbiology and Emmunology, 19-102 (1985). |
Schultz, "Camptothecin," Chem. Rev., 73, (1973) 385-405. |
Muggia, "Phase 1 Clinical Trial of Weekly . . . , " Cancer Chemotherapy Reports Part 1, 56 (1972) 515-521. |
Wani et al., Plant Antitumor Agents. 18. I. Synthesis . . . , J. Med. Chem., 23 (1980) 554-560. |
Giovanella et al. "Correlation Between Response to . . . ," Cancer, 52: 1146-1152 (1983). |
Boven et al., "The Nude Mouse in Oncology Research," CRC Press, Inc., Boca Raton, FL (1991) 305-316. |
Sawada et al., "Chemical Modification of an Antitumor . . . ," Chem. Pharm. Bull. 39 (1991) 2574-2580. |
Sawada et al., "Synthesis and Antitumor Activity . . . ," Chem. Pharm. Bull. 39 (1991), 3183-3188. |
Wani et al. "Plant Antitumor Agents. 23. I. Synthesis . . . ," J. Med. Chem., 29 (1986) 2358-2363. |
Wani et al. "Plant Antitumor Agents. 25.I.. Total . . . ," J. Med. Chem., 30 (1987) 1774-1779. |
Hertzberg et al., "Modification of the Hydroxy Lactone . . . ," J. Med. Chem., 32 (1989) 715-720. |
Kingsbury et al., "Synthesis of Water-Soluble (Aminoalkyl) Camptothecin . . . ," J. Med. Chem., 34 (1991) 98-107. |
Ejima et al., "Antitumor Agents. VI. Synthesis . . . ," Chem. Pharm. Bull., 40 (1992) 683-688. |
Abbott, "Bioassay of Plant Extracts For Anticancer Activity," Cancer Treatment Reports, vol. 80, No. 8, 1007-1010 (1976). |
Baumgarten et al., Naphthyridines I Synthesis of Some 1,7-Naphthyridines, JACS, 77 2438-2440 (1955). |
Borch et al., "A New Method for the Methylation of Amines," J. Org. Chem., vol. 37, No. 10, 1673-1674 (1972). |
Fiebig, "Comparison of Tumor Response in Nude Mice and in Plants," ESO Momographs, Heidleburg, 25-30 (1988). |