Working enclosure provided with means for recycling the atmosphere

Information

  • Patent Grant
  • 6446716
  • Patent Number
    6,446,716
  • Date Filed
    Wednesday, July 5, 2000
    24 years ago
  • Date Issued
    Tuesday, September 10, 2002
    22 years ago
Abstract
A working enclosure includes a working chamber whose walls delimit a confinement space for working in and an exterior branch loop for recycling the atmosphere of the confinement space. The branch loop opens at each end into the confinement space and includes means for circulating the atmosphere in the branch loop. The working enclosure includes filter members at each end of the branch loop.
Description




FIELD OF THE INVENTION




The present invention relates to a working enclosure of the type including a working chamber whose walls delimit a confinement space for working in and an external branch loop for recycling the atmosphere of the confinement space and which opens into the confinement space at both ends and includes means for circulating the atmosphere in the branch loop.




BACKGROUND OF THE INVENTION




Conventional working enclosures of the above kind are routinely thermostatically controlled so that the confinement space is maintained at constant temperature and auxiliary systems are routinely used to procure a high relative humidity.




Enclosures of the above kind are used for working in a controlled atmosphere, for example. One example of such work is the culture of animal cells or embryos. In this case the CO


2


and water vapour content of the atmosphere in the confinement space in particular are monitored.




Depending on the use to which the enclosure is put, it can be contaminated by undesirable germs which develop in the confinement space.




Recycling the atmosphere of the enclosure via an external branch loop provided for this purpose enables continuous treatment, and in particular filtering, of the atmosphere of the enclosure.




A fan or a pump is mounted in the branch to circulate the atmosphere.




A filter is provided at the entry end of the pipe constituting the branch loop relative to the normal direction of flow of the atmosphere in the loop. It holds back contaminating elements when the atmosphere of the enclosure is circulated.




An enclosure of the above kind works well if the fan or the pump is not stopped and the atmosphere circulates through the branch loop.




Contamination of the branch loop is possible if the operation of the pump is interrupted. It is then necessary to decontaminate the whole of the branch loop before restarting the enclosure, which necessitates a great deal of work.




Also, if work on the branch loop necessitates stopping the pump, it is necessary to decontaminate both the confinement space and the branch loop before returning the enclosure to service.




SUMMARY OF THE INVENTION




An object of the invention is to propose a working enclosure which limits the need for manual decontamination of the confinement space and the branch loop.




To this end, the invention provides a working enclosure of the above type characterized in that it includes filter members at each end of said branch loop.




Particular embodiments of the enclosure have one or more of the following features:




the filtration members at each end of the branch loop extend the wall of the chamber through which the branch loop opens;




the working chamber includes a containment vessel and a door mobile relative to the containment vessel and shutting off an access to said containment space and the branch loop is carried by the door, each end of the branch loop opens via the door, and the filter members are carried by the door at each end of the branch loop;




the door has over most of its surface a thermostatically controlled box-section and said branch loop extends over most of its length inside said thermostatically controlled box-section;




the working chamber includes a containment vessel and a door mobile relative to the containment vessel and shutting off an access to said confinement space and each end of the branch loop opens through walls of the containment vessel;




the containment vessel is at least partly surrounded by a thermostatically controlled jacket and said branch loop extends over most of its length inside said thermostatically controlled jacket; and




the containment vessel is at least partly surrounded by a thermostatically controlled jacket filled with a heat-conducting liquid and said branch loop passes through said jacket and extends over the greater part of its length in a thermostatically controlled box-section adjacent said jacket, which box-section contains a gas.











BRIEF DESCRIPTION OF THE DRAWINGS




The invention will be better understood after reading the following description, which is given by way of example only and with reference to the accompanying drawings, in which:





FIG. 1

is a diagrammatic view of an enclosure according to the invention in cross section in a vertical plane passing through the entry opening of the enclosure, and





FIGS. 2 and 3

are diagrammatic views of two embodiments of working enclosure according to the invention in cross section in vertical section planes parallel to the entry opening of the enclosure.











DETAILED DESCRIPTION OF THE INVENTION




The working enclosure


10


shown in

FIG. 1

includes a working chamber


12


inside a thermostatically controlled box


14


. The working chamber delimits a confinement space


16


for working in, for example for incubating cells or embryos. In the conventional way, the enclosure


10


is equipped with means for monitoring the atmosphere of the confinement space and in particular its CO


2


and water vapour content.




The working chamber


12


consists of a substantially parallelepiped-shaped containment vessel


17


one face


18


of which is open. That face is closed by an articulated door


20


adapted to seal an access opening to the confinement space


16


.




The containment vessel


17


which partly delimits the working chamber


12


is accommodated entirely within the thermostatically controlled box


14


. The latter forms a jacket


22


all around the working chamber


12


, except for its open face


18


. The jacket


22


formed in this way is filled with a heat-conducting liquids such as water. The solid walls of the containment vessel


17


are in contact with the heat-conducting liquid.




Means


24


for regulating the temperature of the heat-conducting liquid, such as resistive heating elements, are installed in the thermostatically controlled box


14


.




The door


20


is articulated to the thermostatically controlled box


14


by means of hinges


26


. The door can be moved between a position allowing access to the confinement space


16


via the open face


18


of the working chamber and a position closing the face


18


.




The door


20


has a frame delimited by a sealed box-section


28


filled with a heat-conducting fluid such as water. Means


30


for regulating the temperature of the heat-conducting fluid, such as resistive heating elements, are provided inside the box-section


28


. The box-section


28


is therefore thermostatically controlled and can advantageously be maintained at the same temperature as the jacket


22


.




The face of the door


20


facing the chamber


12


incorporates a plate


32


for sealing off the confinement space


16


. The plate


32


is slightly larger than the open face


18


of the containment vessel. It is adapted to be applied to the edges of the containment vessel in order to seal it hermetically. A peripheral seal is advantageously provided for this purpose.




A branch loop


40


for recycling the atmosphere in the confinement space


16


is integrated into the interior of the door


20


. The branch loop opens at both ends into the interior of the working chamber


12


via the open face


18


thereof.




The branch loop


40


extends from an entry opening


42


to an exit opening


44


, both of which are formed in the closure plate


32


. A suction intake


46


is provided to the rear of the entry opening


42


, which is extended by a duct


48


extending the length of the door inside the box-section


28


. The duct


48


is therefore immersed in the heat-conducting fluid.




The branch loop opens at the exit end


44


via a vent


50


.




A ventilator


52


or a compressor a pump is mounted inside the suction intake


46


to circulate the atmosphere through the branch loop


40


.




According to the invention, respective filter units


54


,


56


are provided at the entry and exit ends of the branch loop


40


. The filter units are identical and are high-efficiency particle air (HEPA) filters, for example. The filters have a mesh diameter of 0.2 μm, for example.




The filter units


54


and


56


are contained within the thickness of the plate


32


and therefore ensure the continuity of this wall of the chamber.




Clearly the branch loop


40


equipped with the fan


52


enables continuous circulation of the atmosphere in the confinement space. Contaminating particles contained in the atmosphere are held back by the filter unit


54


mounted at the entry


42


of the branch loop.




When the enclosure is operating normally, i.e. when the fan


52


is running, the filter unit


56


does not as such contribute to filtering the atmosphere of the enclosure.




On the other hand, if the fan


52


is stopped, with no flow in the branch loop


40


, the filter unit


56


prevents contaminants entering the branch loop


40


via the exit opening


44


.




Likewise, if the door


20


is opened, the two filters


54


and


56


prevent any contamination of the interior of the branch loop


40


.




Most of the length of the branch loop


40


is inside the thermostatically controlled box-section


28


and the atmosphere is therefore not subjected to any variation of temperature as it passes through the loop


40


.




In the embodiments of the invention shown in

FIGS. 2 and 3

elements identical or similar to those shown in

FIG. 1

are designated by the same reference numbers.




In the

FIG. 2

embodiment of the invention the branch loop


70


is not in the door for closing off the confinement space


16


. That door is not shown, but is parallel to and in front of the plane of the figure. The branch loop


70


is inside the jacket


22


delimited by the box


14


and the working chamber


12


.




To be more precise, the branch loop


70


extends along an exterior lateral wall


72


of the box. The branch loop


70


opens via a lateral wall


73


of the containment vessel. To this end, that wall has an entry opening


74


in it through which the atmosphere in the confinement space is collected and an exit opening


76


in it through which the filtered atmosphere is returned.




Each opening


74


and


76


is fitted with a respective filter unit


78


and


80


. The filter units are integrated into the thickness of the wall


73


and have a mesh diameter of 0.2 μm, for example.




As in the previous embodiment, the branch loop includes a suction intake


82


downstream of the filter


78


, a duct


84


and a vent


86


opening into the confinement space


16


via the filter


76


.




A fan is mounted in the branch loop. It has a rotor


88


in the duct


84


downstream of the suction intake


82


. The rotor


88


is rotated by an electric motor


90


which is outside the thermostatically controlled box


14


and inside an auxiliary cabinet


92


.




In this embodiment the filter


78


captures contaminants during continuous circulation of the atmosphere of the working space through the branch loop


70


.




If the fan is stopped, the filter


80


prevents contaminants entering the branch loop


70


, so avoiding the need to decontaminate the branch loop


70


before the enclosure is used again.




In the

FIG. 3

embodiment of the invention the branch loop


100


includes a duct


102


which connects a suction intake


104


to a vent


106


. The intake and the vent open into the space


16


via a lateral wall


108


in which openings


110


,


112


are formed. Each opening is equipped with a filter


114


,


116


. The duct


102


is no longer inside the jacket


22


filled with heat-conducting fluid, but instead in an adjacent thermostatically controlled area


120


. The area


120


is delimited by a cabinet


122


and is filled with air. Resistive heating elements


124


are placed inside the cabinet


122


to maintain the temperature in the area


120


substantially equal to that of the jacket


22


.




A fan rotor


130


is mounted in the branch loop


100


. Its drive motor


132


is inside the thermostatically controlled area


120


.




In this embodiment the filter


116


prevents contaminants entering the branch loop


100


if the fan is stopped.




Maintenance of the branch loop is facilitated because the duct


102


is no longer inside the jacket


22


filled with heat-conducting liquid, but instead in an adjacent thermostatically controlled area which is open to the atmosphere. However, transportation of the atmosphere from the confinement space through the duct


102


while it is being filtered does not vary its temperature, because the area


120


is also thermostatically controlled. This reduces the risk of condensation.




Whichever embodiment of the invention is used, if work has to be carried out on the branch loop, in particular on the fan, it is not necessary to decontaminate the working enclosure when work resumes because the enclosure is protected from contaminants introduced into the branch loop by the filters at both ends thereof.



Claims
  • 1. A working enclosure comprising a working chamber whose walls delimit a confinement space for working in and an exterior branch loop for recycling the atmosphere of the confinement space, which branch loop opens at each end into the confinement space and includes means for circulating the atmosphere in the branch loop, wherein the working enclosure includes filter members at each end of said branch loop,wherein the working chamber includes a containment vessel and a door mobile relative to the containment vessel and shutting off an access to said confinement space and wherein each end of the branch loop opens through walls of the containment vessel, the containment vessel being at least partly surrounded by a thermostatically controlled jacket filled with a heat-conducting liquid and wherein said branch loop passes through said jacket and extends over the greater part of its length in a thermostatically controlled box-section adjacent said jacket, which box-section contains a gas.
  • 2. The working enclosure according to claim 1, wherein the filter members at each end of the branch loop extend the wall of the chamber through which the branch loop opens.
  • 3. A working enclosure comprising a working chamber whose walls delimit a confinement space for working in and an exterior branch loop for recycling the atmosphere of the confinement space, which branch loop opens at each end into the confinement space and includes means for circulating the atmosphere in the branch loop, wherein the working enclosure includes filter members at each end of said branch loop,wherein the working chamber includes a containment vessel and a door mobile relative to the containment vessel and shutting off an access to said confinement space and wherein each end of the branch loop opens through walls of the containment vessel, the containment vessel being at least partly surrounded by a thermostatically controlled jacket and wherein said branch loop extends over most of its length inside said thermostatically controlled jacket.
  • 4. The working enclosure according to claim 3, wherein the filter members at each end of the branch loop extend the wall of the chamber through which the branch loop opens.
  • 5. A working enclosure comprising a working chamber whose walls delimit a confinement space for working in and an exterior branch loop for recycling the atmosphere of the confinement space, which branch loop opens at each end into the confinement space and includes means for circulating the atmosphere in the branch loop, wherein the working enclosure includes filter members at each end of said branch loop,wherein the working chamber includes a containment vessel and a door mobile relative to the containment vessel and shutting off an access to said containment space and wherein the branch loop is carried by the door, each end of the branch loop opens via the door, and the filter members are carried by the door at each end of the branch loop.
  • 6. The working enclosure according to claim 5, wherein the filter members at each end of the branch loop extend the wall of the chamber through which the branch loop opens.
  • 7. The working enclosure according to claim 5, wherein the door has over most of its surface a thermostatically controlled box-section and wherein said branch loop extends over most of its length inside said thermostatically controlled box-section.
Priority Claims (1)
Number Date Country Kind
99 08716 Jul 1999 FR
US Referenced Citations (7)
Number Name Date Kind
3784754 Saunders et al. Apr 1975 A
4449579 Miyazaki et al. May 1984 A
5090476 Immel Feb 1992 A
5792427 Hugh et al. Apr 1998 A
6067233 Diebel et al. May 2000 A
6164369 Stoller Dec 2000 A
6170562 Knoblauch Jan 2001 B1
Foreign Referenced Citations (5)
Number Date Country
296 22 079 Aug 1997 DE
0 195 703 Sep 1986 EP
1 396 883 Jun 1975 GB
WO 9005549 May 1990 WO
WO 9534078 May 1995 WO