Field
The embodiments discussed herein are related to X-ray generation and delivery.
Relevant Technology
An X-ray generating apparatus, or X-ray tube, conventionally includes a vacuum enclosure with an anode assembly and a cathode assembly spaced therebetween. The cathode assembly may include an electron emitting cathode, which is disposed so as to direct a beam of electrons onto a focal spot of an anode target of the anode assembly. In operation, electrons emitted by the cathode are accelerated towards the anode target by a high voltage applied between the cathode and the anode target. The accelerated electrons impinge on the focal spot area of the anode target with sufficient kinetic energy to generate a beam of x-rays which passes through a window in the vacuum enclosure.
X-ray tubes are used in a variety of industrial and medical applications. For example, X-ray tubes are employed in medical diagnostic examination, radiation therapy, semiconductor fabrication, and material analysis. In particular, radiation therapy for cancer treatment has been in use for decades. Conventional radiation therapy systems may employ an X-ray tube configured to generate a point-source X-ray beam, where X-rays may be emitted from the target in a generally conical pattern, which may be initially confined to a generally rectangular beam by a collimator having moveable, x-ray blocking “jaws” in the head of the system. Rarely, however, can the system jaws alone be used to implement a suitable treatment plan.
The subject matter claimed herein is not limited to embodiments that solve any disadvantages or that operate only in environments such as those described above. Rather, this background is only provided to illustrate one example technology area where some embodiments described herein may be practiced.
Embodiments may generally relate to X-ray generation and delivery. In particular, embodiments may relate to systems, devices, and/or methods for X-ray generation and delivery.
This Summary introduces a selection of concepts in a simplified form that are further described below in the Detailed Description. This Summary is not intended to identify key features or essential characteristics of the claimed subject matter, nor is it intended to be used as an aid in determining the scope of the claimed subject matter.
In some embodiments, an X-ray assembly may include a housing, an anode, and a cathode assembly. The anode may be located at least partially within the housing. The anode may include a target area configured such that X-rays generated at the target area form an area-source X-ray beam. The cathode assembly may be located at least partially within the housing and may be positioned to deliver electrons to the target area of the anode from multiple directions relative to the target area, the multiple directions including at least two substantially opposite directions relative to the target area.
In some embodiments, a system may include an X-ray assembly and a focusing collimator. The X-ray assembly may include a housing, an anode, and a cathode. The anode may be located at least partially within the housing. The anode may include a target area. The cathode assembly may be located at least partially within the housing. The cathode assembly may include a cathode and a focusing electrode. The cathode assembly may be positioned to deliver electrons to the target area of the anode from multiple directions relative to the target area. The focusing collimator may include at least one substantially frustoconical passage.
Additional features and advantages will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by the practice of the embodiments. The features and advantages of the embodiments will be realized and obtained by means of the instruments and combinations particularly pointed out in the claims. These and other features will become more fully apparent from the following description and claims, or may be learned by the practice of the embodiments as set forth hereinafter.
To further clarify the above and other advantages and features of the present invention, a more particular description of the invention will be rendered by reference to specific embodiments thereof which are illustrated in the appended drawings. It is appreciated that these drawings depict only typical embodiments of the invention and are therefore not to be considered limiting of its scope. The invention will be described and explained with additional specificity and detail through the use of the accompanying drawings in which:
Reference will now be made to the figures wherein like structures will be provided with like reference designations. The drawings are diagrammatic and schematic representations and, accordingly, are not limiting of the scope of the claimed subject matter, nor are the drawings necessarily drawn to scale.
The cathode 112 may emit electrons, which may impinge the anode 110 at a target area 116. An isolator 118 may discourage electrons from impinging the anode 110 at a location other than the target area 116. The X-ray assembly 102 may include a focusing electrode 114 for steering, focusing, or otherwise influencing the paths of electrons emitted by the cathode 112. The electrons emitted by the cathode 112 may impinge the target area 116 of the anode 110 and may generally produce an X-ray beam 108 that may pass through the X-ray window 106. In some configurations, the X-ray window 106 may be a portion of the housing 104 that the X-ray beam 108 passes through. In some other configurations, the X-ray window 106 may be different from the housing 104 in some way, such as being made from a different material than the housing 104 or the like.
The target area 116 of the anode 110 may have a surface area of less than a few square millimeters (mm). For example, in some configurations, the target area 116 of the anode 110 may have a surface area of about 1 mm. Thus, for example, the X-ray beam 108 may appear to be originating from a relatively small area. Thus, for practical purposes, the X-ray beam 108 may behave as if originating from a point source.
A radiation intensity diagram 122 illustrates a cross-section of a relative intensity 124 of the radiation generated at the target area 116. The relative intensity 124 is shown according to a color scale 126.
As demonstrated in the radiation intensity diagram 122, levels of radiation intensity 123 generated by the point-source X-ray system 100 may be relatively weak. Furthermore, the sections of relatively consistent intensity may be approximately small and may be relatively shaped as a spherical cap. Put another way, the spherical radiation intensity may not include an area with a relatively consistent, flat intensity.
Thus, for example, the X-ray system 100 may produce a relatively low-power X-ray beam 108. Point-source X-ray systems may be used for radiation treatment of surfaces and/or internal volumes of a body. However, using the relatively low-power X-ray beam for radiation therapy may lead to longer exposure times and/or relatively high exposure to areas of the body that do not require treatment. As a result, treatment via point-source X-ray systems may be accompanied by a risk of damaging healthy portions of a body in the course of treating unhealthy portions.
The assembly 202 includes a cathode assembly 212. The cathode assembly 212 includes a cathode 213 and may further include a focusing electrode 214. The cathode 213 and/or the focusing electrode 214 may be positioned to deliver electrons to the target area 216 of the anode 210 from multiple directions relative to the anode 210. For example, the cathode assembly 212 may be positioned on opposite sides of the target area of the anode 210. In some embodiments, the cathode 213 and/or the focusing electrode 214 may be positioned at an offset relative to an edge of the target area 216. For example, the cathode assembly 212 may include a substantially circular shape positioned around the target area 216 having a dish shape. In some embodiments, by delivering electrons to the target area 216 from multiple directions, the target area 216 may be impinged by electrons over its relatively large area. Thus, for example, an X-ray beam 208 may be produced over the relatively large area of the target area 216. In this and other embodiments, the cathode assembly 212 may be omitted and the target area 216 may be replaced or covered with a radioactive isotope. Thus, for example, X-ray generation may occur without the cathode assembly 212 or an electron stream.
A radiation intensity diagram 222 illustrates a cross-section of a relative radiation intensity 224 of X-rays generated at the target area 216. The relative intensity 224 is shown according to a color scale 226.
As illustrated in the radiation intensity diagram 222, the highest relative level of radiation intensity 223 generated by the X-ray system 200 may be relatively higher through a relatively larger volume than conventional point-source X-ray systems, such as the X-ray system 100 of
An area X-ray assembly, such as the X-ray system 200 of
In some embodiments, the cathode 213 and the focusing electrode 214 may be configured to vary the intensity of the electron stream over the target area 216. Varying the intensity of the electron stream over the target area 216 may, in turn, vary the intensity of the X-rays generated across the target area 216.
The target area 216 may include a disk shape, as illustrated. In some embodiments, the target area 216 may include any other suitable shape, such as another elliptical shape, a planar donut shape, a rectangular or other polygon shape, or the like or any combination thereof. Furthermore, in this and other embodiments, the target area 216 may include a three-dimensional shape in order to shape the X-ray beam intensity profile. The cathode assembly 212 may be shaped to correspond to the shape of the target area 216 and/or to deliver electrons to the target area 216 in a desired manner. Furthermore, in this and other embodiments, the anode 210 may include multiple point-source target areas arranged to perform collectively in a manner similar to an area-source target area.
In this and other embodiments, the shapes of the target area and the anode are provided as an example. The shape of the target area may generally include any shape suitable for producing an X-ray beam such that the X-ray beam originates from an area source. In this and other embodiments, the configuration and position of the cathode assembly are provided as an example. The cathode assembly may generally be configured and positioned to deliver electrons over the target area. In some embodiments, the cathode assembly may be configured and positioned to deliver electrons to the target area from multiple directions relative to the target area, including a continuous cathode around the target area of the anode. In this and other embodiments, the multiple directions may include substantially opposite directions relative to the target area. For example, portions of the cathode assembly located on opposite sides of the target area may deliver electrons to the target area from substantially opposite directions relative to the target area.
The cathodes 304 and/or the focusing electrodes 306 may deliver multiple electron streams, represented by the arrows 308, to a target area 310 from multiple directions relative to the target area 310. In some embodiments, the cathodes 304 and/or the focusing electrodes 306 may be configured to direct the electron streams relatively consistently over the target area 310. The cathodes 304 and the focusing electrodes 306 may be positioned to correspond to the shape of the target area 310 and/or to deliver electrons to the target area 310 in a desired manner.
The assembly 402 includes an anode 410 having a target area 416. The target area 416 may include a concave surface oriented in a ring shape. The target area 416 may be described herein as a concave ring shape or a non-planar donut shape. The assembly 402 also includes a cathode assembly 412. The cathode assembly 412 includes a cathode 413 and may include a focusing electrode 414. Conductive lines 411 may be used for power and control of the cathode assembly 412. In some embodiments, the target area 416, the anode 410 and/or the cathode 413 and focusing electrode 414 may be circular about a vertical axis. As illustrated in
A radiation intensity diagram 422 illustrates a relative intensity 424 of X-rays generated by the X-ray system 400. The relative intensity 424 is shown according to a color scale 426.
As illustrated in the radiation intensity diagram 422, the highest relative level of radiation intensity 423 generated by the X-ray system 400 may be relatively higher through a relatively larger volume than conventional point-source X-ray systems, such as the X-ray system 100 of
Referring collectively to
A radiation intensity diagram 622 illustrates a relative intensity 624 of X-rays generated at the target area 616. The relative intensity 624 is shown according to a color scale 626.
As illustrated in the radiation intensity diagram 622, the highest relative level of radiation intensity 623 generated by the X-ray system 600 may be relatively higher through a relatively larger volume than conventional point-source X-ray systems, such as the X-ray system 100 of
The assembly 702 may include a cathode assembly 712. The cathode assembly 712 includes a cathode 713 and may further include a focusing electrode 714. The cathode assembly 712 may include a single cathode or multiple cathodes. The assembly 702 may produce an X-ray beam 708.
In some embodiments, the shape of a target area and/or the number of target areas of an anode of an X-ray system may correspond to a collimator to be employed with the X-ray assembly. For example, a target area corresponding to the target area 416 of
The collimator 802 may be positioned between an area-source X-ray assembly and a body 812. The area-source X-ray assembly may include, for example, a housing 801 and an anode having a target area 806. The target area 806 may generally correspond to the target area 616 of
The target area 806 may produce an X-ray beam 810. Portions of the X-ray beam 810 that would be attenuated by the collimator 802 are omitted for clarity. The shape of the X-ray passage 804 may create a relatively cone-shaped X-ray beam 810 below the collimator 802 that meets at a treatment volume 814. In this and other embodiments, collimator 802 profile may be custom shaped to create a treatment volume 814 corresponding to a particular patient's particular tumor shape. Additionally, multiple collimators corresponding to the collimator 802 may be designed to create the desired treatment volume 814 shape from various perspectives relative to a patient's body. Thus, for example, multiple X-ray sources may be used with the multiple collimators to deliver relatively high radiation intensity to a particular treatment volume from multiple locations relative to a patient's body. In this and other embodiments, the collimator 802 may be manufactured via 3D printing processes and/or other rapid manufacturing processes.
Thus, for example, the collimator 802 may allow radiation treatment of a treatment volume 814 such as a tumor or the like, below a surface of the body 812 while limiting the radiation experienced by other portions of the body 812. For example, the treatment volume 814 may be exposed to higher radiation intensity than other parts of the body 812, which may allow treatment inside of the body 812 without damaging surrounding tissue. Furthermore, radiation treatment of the treatment volume 814 may be accomplished with a single X-ray assembly and collimator 802, which may be held stationary relative to the body 812.
In this and other embodiments, the X-ray system 800 may be used to perform radiation treatment by changing the relative position of the X-ray system 800 relative to a body, such as the body of a human patient, to be treated. In some embodiments, the X-ray system 800 may be moved dynamically (e.g., moved as the X-ray beam 810 is being produced) relative to the body. Alternately, the X-ray system 800 may be moved in a point-and-shoot manner (e.g., moved when the production of the X-ray beam 810 is ceased) relative to the body.
The collimator 902 may be positioned between an area-source X-ray assembly and a body 912. The area-source X-ray assembly may include, for example, a housing 901 and an anode having multiple ring-shaped target areas 906. Alternately, the area-source X-ray assembly may include an anode having a differently shaped target area. The target areas 906 are illustrated to demonstrate example three-dimensional attributes of the target areas 906. Furthermore, the remaining X-ray assembly associated with the target areas 906 is omitted for clarity. The target areas 906 may produce X-ray beams 910. Portions of the X-ray beams 910 that would be attenuated by the collimator 902 are omitted for clarity.
The shape of each of the X-ray passages 904 may create a corresponding, relatively cone-shaped X-ray beam 910 below the collimator 902. The X-ray passages 904 are convergent. For example, each of the X-ray passages 904 may be positioned such that each of the relatively cone-shaped X-ray beams 910 meet approximately at substantially the same treatment volume 914 in a body 912.
The collimator 1002 may be positioned between an area-source X-ray assembly and a body 1012. The area-source X-ray assembly may include, for example, a housing 1001 and an anode having a target area 1006. The target area 1006 may generally correspond to the target area 616 of
The shape of each of the X-ray passages 1004 may create a corresponding, relatively cone-shaped X-ray beam 1010 below the collimator 1002. The X-ray passages 1004 are divergent. For example, each of the X-ray passages 1004 may be positioned such that each of the relatively cone-shaped X-ray beams 1010 meet at multiple treatment volumes 1014 in a body 1012. In embodiments including relatively circular X-ray passages 1004, the treatment volumes 1014 may include a three-dimensional shape resembling a target volume 1014a encircled by a ring-shaped target volume 1014b. In some embodiments, the X-ray passages 1004 may be configured to create treatment volumes 1014 more closely or more distantly positioned.
The collimator 1102 may be positioned between an area-source X-ray assembly and a body 1112. The area-source X-ray assembly may include, for example, a housing 1101 and an anode having a target area 1106. The target area 1106 may generally correspond to the target area 416 of
The shape of each of the X-ray passages 1104 may create a corresponding, relatively cone-shaped X-ray beam 1110 below the collimator 1102. The X-ray passages 1104 are parallel. Conceptually, the X-ray passages 1104 may alternately be considered to include a single, relatively large X-ray passage 1104 including multiple concentric walls 1105. By way of example, the parallel X-ray passages 1104 may result in a relatively laminar, relatively cone-shaped X-ray beam 1110 that meets at a relatively large treatment volume 1114 in a body 1112.
The collimator 1202 may be positioned between an area-source X-ray assembly and a body 1212. The area-source X-ray assembly may include, for example, a housing 1201 and an anode having a target area 1206. The target area 1206 may generally correspond to the target area 716 of
The shape of the X-ray passage 1204 may create a corresponding, relatively cone-shaped X-ray beam 1210 below the collimator 1202. Furthermore, the frustoconical target area 1206 may produce a relatively frustoconical X-ray beam 1210. Thus, for example, a relatively high portion of the X-rays produced at the target area 1206 may be directed to the body 1212 and to the treatment volume 1214.
The X-ray system 1300 may include a target area 1302 of an anode of an X-ray assembly. Portions of the X-ray assembly other than the target area 1302 and the collimator are omitted for clarity. The target area 1302 may be relatively thin, such that an electron beam 1304 striking one side of the target area 1302 may produce an X-ray beam 1308 on the other side of the target area 1302. The electron beam 1304 may be steered in a relatively circular motion, represented by arrow 1306. Thus, for example, the electron beam 1304 may strike the target area 1302 in a pattern approximating a circle and the X-ray beam 1308 may be produced in a pattern also approximating the circle. Each of the positions of X-ray beam 1308 may intersect at an approximate treatment volume 1310.
By way of example, at a first time, the electron beam 1304a may result, in part, in the X-ray beam 1308a. Portions of the resulting X-ray beam that do not pass through the treatment volume 1310 are omitted for clarity. Furthermore, at a second time, the electron beam 1304b may result, in part in the X-ray beam 1308b. Thus, for example, the treatment volume 1310 may be subject to a relatively higher radiation intensity, while the surrounding volumes may be subject to lower radiation intensities. Thus, for example, a treatment volume 1310, such as a tumor in a body or the like, may be targeted by a relatively stationary X-ray assembly.
The X-ray system 1400 may include an electron beam 1404, an X-ray beam 1408, and a treatment volume 1410 generally corresponding to the electron beam 1304, the X-ray beam 1308, and the treatment volume 1310 of
The X-ray system 1400 includes a target area 1402 of an anode of an X-ray assembly. Portions of the X-ray assembly other than the target area 1402 are omitted for clarity. The target area 1402 may have a ring shape. For example, the target area 1402 may have a ring shape analogous to the target area 616 of
By way of example, the target area 1402 may have a target area shape corresponding to the target area 1106 of
The present invention may be embodied in other specific forms without departing from its spirit or essential characteristics. The described embodiments are to be considered in all respects only as illustrative and not restrictive. The scope of the invention is, therefore, indicated by the appended claims rather than by the foregoing description. All changes that come within the meaning and range of equivalency of the claims are to be embraced within their scope.