Bradford Hirth

Person

Waltham, MA, US

People

Patents Grantslast 30 patents

Information Patent Grant
Glucosylceramide synthase inhibitors
- Patent number 12,060,349
- Issue date Aug 13, 2024
- Genzyme Corporation
- Elyse Bourque
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
UDP glycosyltransferase inhibitors and methods of use
- Patent number 11,098,056
- Issue date Aug 24, 2021
- Genzyme Corporation
- Sungtaek Lim
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Glucosylceramide synthase inhibitors
- Patent number 11,008,316
- Issue date May 18, 2021
- Genzyme Corporation
- Elyse Bourque
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Modulators of TNF-α signaling
- Patent number 9,579,325
- Issue date Feb 28, 2017
- Genzyme Corporation
- Scott F. Sneddon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyl transferase in...
- Patent number 9,546,161
- Issue date Jan 17, 2017
- Genzyme Corporation
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Glucosylceramide synthase inhibitors
- Patent number 9,139,580
- Issue date Sep 22, 2015
- Genzyme Corporation
- Elyse Bourque
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Glucosylceramide synthase inhibitors
- Patent number 9,126,993
- Issue date Sep 8, 2015
- Genzyme Corporation
- Elyse Bourque
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modulators of TNF-α signaling
- Patent number 8,921,547
- Issue date Dec 30, 2014
- Genzyme Corporation
- Scott F. Sneddon
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Synthesis of UDP-Glucose: N-acylsphingosine glucosyl transferase in...
- Patent number 8,779,163
- Issue date Jul 15, 2014
- Genzyme Corporation
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Inhibitors of S-adenosyl-L-methionine decarboxylase
- Patent number 8,633,168
- Issue date Jan 21, 2014
- Genzyme Corporation
- Yibin Xiang
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Modulators of TNF-αsignaling
- Patent number 8,518,999
- Issue date Aug 27, 2013
- Genzyme Corporation
- Scott F. Sneddon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
- Patent number 8,138,353
- Issue date Mar 20, 2012
- Genzyme Corporation
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
- Patent number 7,763,738
- Issue date Jul 27, 2010
- Genzyme Corporation
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Tetrahydroisoquinoline derivatives for treating protein trafficking...
- Patent number 7,541,466
- Issue date Jun 2, 2009
- Genzyme Corporation
- Marko J. Pregel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
- Patent number 7,265,228
- Issue date Sep 4, 2007
- Genzyme Corporation
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Diastereoselective synthesis of UDP-glucose: N-acylsphingosine gluc...
- Patent number 7,041,831
- Issue date May 9, 2006
- Genzyme Corporation
- Bradford H. Hirth
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Modulators of TNF-α signaling
- Patent number 7,034,031
- Issue date Apr 25, 2006
- Genzyme Corporation
- Scott F. Sneddon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modulators of TNF-α signaling
- Patent number 6,969,728
- Issue date Nov 29, 2005
- Genzyme Corporation
- Scott F. Sneddon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
- Patent number 6,855,830
- Issue date Feb 15, 2005
- Genzyme Corporation
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Diastereoselective synthesis of UDP-glucose: N-acylsphingosine gluc...
- Patent number 6,835,831
- Issue date Dec 28, 2004
- Genzyme Corporation
- Bradford H. Hirth
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibacterial compounds
- Patent number 6,410,533
- Issue date Jun 25, 2002
- Genzyme Corporation
- Bradford H. Hirth
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Substituted N-arylmethylamino derivatives of cyclobutene-3,4-diones
- Patent number 5,846,999
- Issue date Dec 8, 1998
- American Home Products Corporation
- Madelene M. Antane
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Substituted N-arylmethylamino derivatives of cyclobutene-3, 4-diones
- Patent number 5,780,505
- Issue date Jul 14, 1998
- American Home Products Corporation
- Madelene M. Antane
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Substituted N-arylmethylamino derivatives of cyclobutene-3,4-diones
- Patent number 5,763,474
- Issue date Jun 9, 1998
- American Home Products Corporation
- David R. Herbst
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Substituted N-heteroaryl-1,2-diaminocyclobutene-3,4-dione compounds
- Patent number 5,605,909
- Issue date Feb 25, 1997
- American Home Products Corporation
- John A. Butera
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Diaminocyclobutene-3,4-diones
- Patent number 5,536,731
- Issue date Jul 16, 1996
- American Home Products Corporation
- Madelene M. Antane
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Diaminocyclobutene-3,4-diones
- Patent number 5,536,741
- Issue date Jul 16, 1996
- American Home Products Corporation
- Madelene M. Antane
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Substituted N-heteroaryl-1,2-diaminocyclobutene-3,4-dione compounds
- Patent number 5,532,245
- Issue date Jul 2, 1996
- American Home Products Corporation
- John A. Butera
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Diaminocyclobutene-3,4-diones
- Patent number 5,530,025
- Issue date Jun 25, 1996
- American Home Products Corporation
- Madelene M. Antane
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Diaminocyclobutene-3,4-diones
- Patent number 5,512,585
- Issue date Apr 30, 1996
- American Home Products Corporation
- Madelene M. Antane
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
INDOLE COMPOUNDS AND METHODS OF USE
- Publication number 20240279220
- Publication date Aug 22, 2024
- Genzyme Corporation
- Junkai Liao
- C07 - ORGANIC CHEMISTRY
Information Patent Application
INDOLE COMPOUNDS AND METHODS OF USE
- Publication number 20240239784
- Publication date Jul 18, 2024
- Genzyme Corporation
- Junkai Liao
- C07 - ORGANIC CHEMISTRY
Information Patent Application
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
- Publication number 20220073508
- Publication date Mar 10, 2022
- Genzyme Corporation
- Elyse Bourque
- C07 - ORGANIC CHEMISTRY
Information Patent Application
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
- Publication number 20210261557
- Publication date Aug 26, 2021
- Genzyme Corporation
- Elyse BOURQUE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...
- Publication number 20210171507
- Publication date Jun 10, 2021
- Genzyme Corporation
- Bradford H. Hirth
- C07 - ORGANIC CHEMISTRY
Information Patent Application
UDP GLYCOSYLTRANSFERASE INHIBITORS AND METHODS OF USE
- Publication number 20200102324
- Publication date Apr 2, 2020
- Genzyme Corporation
- Sungtaek LIM
- C07 - ORGANIC CHEMISTRY
Information Patent Application
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
- Publication number 20200048266
- Publication date Feb 13, 2020
- Genzyme Corporation
- Elyse BOURQUE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...
- Publication number 20190322649
- Publication date Oct 24, 2019
- Genzyme Corporation
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
- Publication number 20180065957
- Publication date Mar 8, 2018
- Genzyme Corporation
- Elyse Bourque
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...
- Publication number 20170334888
- Publication date Nov 23, 2017
- Genzyme Corporation
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
- Publication number 20160207933
- Publication date Jul 21, 2016
- Genzyme Corporation
- Elyse BOURQUE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
- Publication number 20150210681
- Publication date Jul 30, 2015
- Genzyme Corporation
- Elyse Bourque
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYL TRANSFERASE IN...
- Publication number 20150148534
- Publication date May 28, 2015
- Bradford H. Hirth
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Modulators Of TNF-Alpha Signaling
- Publication number 20150126512
- Publication date May 7, 2015
- Genzyme Corporation
- Scott F. Sneddon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
- Publication number 20140371460
- Publication date Dec 18, 2014
- Elyse BOURQUE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
- Publication number 20140255381
- Publication date Sep 11, 2014
- Genzyme Corporation
- Elyse BOURQUE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Modulators of TNF-Alpha Signaling
- Publication number 20130310388
- Publication date Nov 21, 2013
- Genzyme Corporation
- Scott F. Sneddon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYL TRANSFERASE IN...
- Publication number 20120296088
- Publication date Nov 22, 2012
- Genzyme Corporation
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
INHIBITORS OF SPHINGOSINE KINASE 1
- Publication number 20110275673
- Publication date Nov 10, 2011
- Yibin Xiang
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...
- Publication number 20110003987
- Publication date Jan 6, 2011
- Genzyme Corporation
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
INHIBITORS OF S-ADENOSYL-L-METHIONINE DECARBOXYLASE
- Publication number 20100261668
- Publication date Oct 14, 2010
- Yibin Xiang
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...
- Publication number 20080058514
- Publication date Mar 6, 2008
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Novel small molecules with selective cytotoxicity against human mic...
- Publication number 20070254894
- Publication date Nov 1, 2007
- John L. Kane
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Synthesis of nojirimycins
- Publication number 20070015793
- Publication date Jan 18, 2007
- MACROZYME DNM B.V.
- Bradford H. Hirth
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Modulators of TNF-alpha signaling
- Publication number 20060173010
- Publication date Aug 3, 2006
- Scott F. Sneddon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Tetrahydroisoquinoline derivatives for treating protein trafficking...
- Publication number 20050176761
- Publication date Aug 11, 2005
- Genzyme Corporation
- Marko J. Pregel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Diastereoselective synthesis of UDP-glucose: N-acylsphingosine gluc...
- Publication number 20050075381
- Publication date Apr 7, 2005
- Bradford H. Hirth
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
- Publication number 20050009872
- Publication date Jan 13, 2005
- Genzyme Corporation
- Bradford H. Hirth
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Modulators of TNF-alfa signaling
- Publication number 20040171617
- Publication date Sep 2, 2004
- Genzyme Corporation
- Scott F. Sneddon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Diastereoselective synthesis of UDP-glucose: N-acylsphingosine gluc...
- Publication number 20030153768
- Publication date Aug 14, 2003
- Genzyme Corporation
- Bradford H. Hirth
- C07 - ORGANIC CHEMISTRY

Bradford Hirth

Person

Patents Grantslast 30 patents

Glucosylceramide synthase inhibitors

UDP glycosyltransferase inhibitors and methods of use

Glucosylceramide synthase inhibitors

Modulators of TNF-α signaling

Synthesis of UDP-glucose: N-acylsphingosine glucosyl transferase in...

Glucosylceramide synthase inhibitors

Glucosylceramide synthase inhibitors

Modulators of TNF-α signaling

Synthesis of UDP-Glucose: N-acylsphingosine glucosyl transferase in...

Inhibitors of S-adenosyl-L-methionine decarboxylase

Modulators of TNF-αsignaling

Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...

Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...

Tetrahydroisoquinoline derivatives for treating protein trafficking...

Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...

Diastereoselective synthesis of UDP-glucose: N-acylsphingosine gluc...

Modulators of TNF-α signaling

Modulators of TNF-α signaling

Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...

Diastereoselective synthesis of UDP-glucose: N-acylsphingosine gluc...

Antibacterial compounds

Substituted N-arylmethylamino derivatives of cyclobutene-3,4-diones

Substituted N-arylmethylamino derivatives of cyclobutene-3, 4-diones

Substituted N-arylmethylamino derivatives of cyclobutene-3,4-diones

Substituted N-heteroaryl-1,2-diaminocyclobutene-3,4-dione compounds

Diaminocyclobutene-3,4-diones

Diaminocyclobutene-3,4-diones

Substituted N-heteroaryl-1,2-diaminocyclobutene-3,4-dione compounds

Diaminocyclobutene-3,4-diones

Diaminocyclobutene-3,4-diones

Patents Applicationslast 30 patents

INDOLE COMPOUNDS AND METHODS OF USE

INDOLE COMPOUNDS AND METHODS OF USE

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...

UDP GLYCOSYLTRANSFERASE INHIBITORS AND METHODS OF USE

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYL TRANSFERASE IN...

Modulators Of TNF-Alpha Signaling

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

Modulators of TNF-Alpha Signaling

SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYL TRANSFERASE IN...

INHIBITORS OF SPHINGOSINE KINASE 1

SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...

INHIBITORS OF S-ADENOSYL-L-METHIONINE DECARBOXYLASE

SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...

Novel small molecules with selective cytotoxicity against human mic...

Synthesis of nojirimycins

Modulators of TNF-alpha signaling

Tetrahydroisoquinoline derivatives for treating protein trafficking...

Diastereoselective synthesis of UDP-glucose: N-acylsphingosine gluc...

Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...

Modulators of TNF-alfa signaling

Diastereoselective synthesis of UDP-glucose: N-acylsphingosine gluc...