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Craig CREWS
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New Haven, CT, US
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Patents Grants
last 30 patents
Information
Patent Grant
Compounds and methods for the targeted degradation of bromodomain-...
Patent number
12,171,831
Issue date
Dec 24, 2024
ARVINAS OPERATIONS, INC.
Yimin Qian
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compounds and methods for the targeted degradation of rapidly accel...
Patent number
11,986,531
Issue date
May 21, 2024
ARVINAS OPERATIONS, INC.
Andrew P. Crew
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Imide-based modulators of proteolysis and associated methods of use
Patent number
11,834,460
Issue date
Dec 5, 2023
Yale University
Craig M. Crews
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compounds and methods for the targeted degradation of bromodomain-c...
Patent number
11,554,171
Issue date
Jan 17, 2023
ARVINAS OPERATIONS, INC.
Yimin Qian
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compounds and methods for the enhanced degradation of targeted prot...
Patent number
11,512,083
Issue date
Nov 29, 2022
ARVINAS OPERATIONS, INC.
Andrew P. Crew
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Imide-based modulators of proteolysis and associated methods of use
Patent number
11,220,515
Issue date
Jan 11, 2022
Yale University
Craig M. Crews
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Modulators of BTK proteolysis and methods of use
Patent number
11,028,088
Issue date
Jun 8, 2021
Yale University
Craig M. Crews
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
EGFR proteolysis targeting chimeric molecules and associated method...
Patent number
10,994,015
Issue date
May 4, 2021
ARVINAS OPERATIONS, INC.
Andrew P. Crew
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compounds and methods for the targeted degradation of fetal liver k...
Patent number
10,806,737
Issue date
Oct 20, 2020
ARVINAS OPERATIONS, INC.
Andrew P. Crew
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compounds and methods for the targeted degradation of bromodomain-c...
Patent number
10,772,962
Issue date
Sep 15, 2020
ARVINAS OPERATIONS, INC.
Yimin Qian
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Hydrophobically tagged small molecules as inducers of protein degra...
Patent number
RE48175
Issue date
Aug 25, 2020
Dana-Farber Cancer Institute, Inc.
Nathanael Gray
Information
Patent Grant
Compounds and methods for the enhanced degradation of targeted prot...
Patent number
10,730,870
Issue date
Aug 4, 2020
ARVINAS OPERATIONS, INC.
Andrew P. Crew
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compounds and methods for the enhanced degradation of targeted prot...
Patent number
10,730,862
Issue date
Aug 4, 2020
Yale University
Craig M. Crews
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compounds and methods for the targeted degradation of rapidly accel...
Patent number
10,723,717
Issue date
Jul 28, 2020
ARVINAS OPERATIONS, INC.
Andrew P. Crew
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Modulators of estrogen receptor proteolysis and associated methods...
Patent number
10,604,506
Issue date
Mar 31, 2020
ARVINAS OPERATIONS, INC.
Andrew P. Crew
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Small-molecule hydrophobic tagging of fusion proteins and induced d...
Patent number
10,145,848
Issue date
Dec 4, 2018
Yale University
Craig M. Crews
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Estrogen-related receptor alpha based protac compounds and associat...
Patent number
10,071,164
Issue date
Sep 11, 2018
Yale University
Andrew Crew
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Proteolysis targeting chimera compounds and methods of preparing an...
Patent number
9,938,264
Issue date
Apr 10, 2018
Yale University
Craig Crews
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Hydrophobically tagged small molecules as inducers of protein degra...
Patent number
9,758,522
Issue date
Sep 12, 2017
Dana-Farber Cancer Institute, Inc.
Nathanael Gray
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Small-molecule hydrophobic tagging of fusion proteins and induced d...
Patent number
9,632,089
Issue date
Apr 25, 2017
Yale University
Craig M. Crews
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Small-molecule hydrophobic tagging of fusion proteins and induced d...
Patent number
9,500,653
Issue date
Nov 22, 2016
Yale University
Craig M. Crews
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compounds for enzyme inhibition
Patent number
8,324,174
Issue date
Dec 4, 2012
Onyx Therapeutics, Inc.
Mark S. Smyth
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compounds for enzyme inhibition
Patent number
8,129,346
Issue date
Mar 6, 2012
Onyx Therapeutics, Inc.
Mark S. Smyth
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compounds for enzyme inhibition
Patent number
8,088,741
Issue date
Jan 3, 2012
Onyx Therapeutics, Inc.
Mark S. Smyth
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compounds for enzyme inhibition
Patent number
7,491,704
Issue date
Feb 17, 2009
Proteolix, Inc.
Mark S. Smyth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Enzyme inhibition
Patent number
7,476,650
Issue date
Jan 13, 2009
Yale University
Craig M. Crews
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compounds for enzyme inhibition
Patent number
7,232,818
Issue date
Jun 19, 2007
Proteolix, Inc.
Mark S. Smyth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Proteolysis targeting chimeric pharmaceutical
Patent number
7,208,157
Issue date
Apr 24, 2007
California Institute of Technology
Raymond J. Dashaies
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Proteolysis targeting chimeric pharmaceutical
Patent number
7,041,298
Issue date
May 9, 2006
California Institute of Technology
Raymond J. Deshaies
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Enzyme inhibition
Patent number
6,831,099
Issue date
Dec 14, 2004
Yale University
Craig M. Crews
C07 - ORGANIC CHEMISTRY
Patents Applications
last 30 patents
Information
Patent Application
EGFR PROTEOLYSIS TARGETING CHIMERIC MOLECULES AND ASSOCIATED METHOD...
Publication number
20240382599
Publication date
Nov 21, 2024
Arvinas Operations, Inc.
Andrew P. Crew
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
IMIDE-BASED MODULATORS OF PROTEOLYSIS AND METHODS OF USE
Publication number
20240368179
Publication date
Nov 7, 2024
Yale University
Craig M. CREWS
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Compounds & Methods for the Enhanced Degradation of Targeted Protei...
Publication number
20240317729
Publication date
Sep 26, 2024
Yale University
CRAIG M. CREWS
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE
Publication number
20240299366
Publication date
Sep 12, 2024
Arvinas Operations, Inc.
Andrew P. CREW
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF THE ANDROGEN...
Publication number
20240059686
Publication date
Feb 22, 2024
Arvinas Operations, Inc.
Andrew P. CREW
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECE...
Publication number
20230331681
Publication date
Oct 19, 2023
Arvinas Operations, Inc.
Michael BERLIN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BROMODOMAIN-C...
Publication number
20230263893
Publication date
Aug 24, 2023
Arvinas Operations, Inc.
Yimin QIAN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOUNDS AND METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROT...
Publication number
20230203030
Publication date
Jun 29, 2023
Arvinas Operations, Inc.
Andrew P. Crew
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME
Publication number
20230082997
Publication date
Mar 16, 2023
Arvinas Operations, Inc.
Michael Berlin
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOUNDS AND METHODS FOR TARGETED DEGRADATION OF KRAS
Publication number
20220370416
Publication date
Nov 24, 2022
Arvinas Operations, Inc.
Ling Chu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECE...
Publication number
20220259154
Publication date
Aug 18, 2022
Arvinas Operations, Inc.
Michael BERLIN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MDM2-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE
Publication number
20220127279
Publication date
Apr 28, 2022
Arvinas Operations, Inc.
Andrew P. Crew
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE
Publication number
20220112211
Publication date
Apr 14, 2022
Yale University
Craig M. CREWS
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE
Publication number
20220089570
Publication date
Mar 24, 2022
Arvinas Operations, Inc.
Andrew P. CREW
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
EGFR PROTEOLYSIS TARGETING CHIMERIC MOLECULES AND ASSOCIATED METHOD...
Publication number
20210220475
Publication date
Jul 22, 2021
Arvinas Operations, Inc.
Andrew P. Crew
C07 - ORGANIC CHEMISTRY
Information
Patent Application
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BROMODOMAIN-C...
Publication number
20210187108
Publication date
Jun 24, 2021
Arvinas Operations, Inc.
Yimin Qian
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECE...
Publication number
20210171470
Publication date
Jun 10, 2021
Arvinas Operations, Inc.
Andrew P. CREW
C07 - ORGANIC CHEMISTRY
Information
Patent Application
TETRAHYDRONAPHTHALENE AND TETRAHYDROISOQUINOLINE DERIVATIVES AS EST...
Publication number
20210139458
Publication date
May 13, 2021
Arvinas Operations, Inc.
Andrew P. Crew
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECE...
Publication number
20210009528
Publication date
Jan 14, 2021
Arvinas Operations, Inc.
Andrew P. CREW
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOUNDS AND METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROT...
Publication number
20200392131
Publication date
Dec 17, 2020
Arvinas Operations, Inc.
Andrew P. Crew
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Proteolysis Targeting Chimera Compounds and Methods of Preparing an...
Publication number
20200325130
Publication date
Oct 15, 2020
Yale University
Craig CREWS
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ALLOSTERIC BCR-ABL PROTEOLYSIS TARGETING CHIMERIC COMPOUNDS
Publication number
20200297725
Publication date
Sep 24, 2020
Yale University
Craig M. CREWS
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Phosphatase Binding Compounds and Methods of Using Same
Publication number
20200268897
Publication date
Aug 27, 2020
Yale University
Craig Crews
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MODULATORS OF ESTROGEN RECEPTOR PROTEOLYSIS AND ASSOCIATED METHODS...
Publication number
20200199107
Publication date
Jun 25, 2020
Arvinas Operations, Inc.
Andrew P. Crew
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME
Publication number
20200155689
Publication date
May 21, 2020
Arvinas Operations, Inc.
ANDREW P. CREW
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME
Publication number
20200155690
Publication date
May 21, 2020
Arvinas Operations, Inc.
ANDREW P. CREW
C07 - ORGANIC CHEMISTRY
Information
Patent Application
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCEL...
Publication number
20200129627
Publication date
Apr 30, 2020
Arvinas Operations, Inc.
ANDREW P. CREW
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MODULATORS OF BTK PROTEOLYSIS AND METHODS OF USE
Publication number
20200121684
Publication date
Apr 23, 2020
Yale University
Craig M. Crews
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECE...
Publication number
20200095205
Publication date
Mar 26, 2020
Arvinas, Inc.
Andrew P. Crew
C07 - ORGANIC CHEMISTRY
Information
Patent Application
COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECE...
Publication number
20200055825
Publication date
Feb 20, 2020
Arvinas Operations, Inc.
Andrew P. Crew
C07 - ORGANIC CHEMISTRY