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Craig Siegel
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Woburn, MA, US
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Patents Grants
last 30 patents
Information
Patent Grant
Amorphous and a crystalline form of genz 112638 hemitartrate as inh...
Patent number
11,458,119
Issue date
Oct 4, 2022
Genzyme Corporation
Hanlan Liu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Method of preparing glucosylceramide synthase inhibitors
Patent number
10,954,230
Issue date
Mar 23, 2021
Genzyme Corporation
Craig S. Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Method of preparing glucosylceramide synthase inhibitors
Patent number
10,604,518
Issue date
Mar 31, 2020
Genzyme Corporation
Craig S. Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Method of preparing glucosylceramide synthase inhibitors
Patent number
10,065,949
Issue date
Sep 4, 2018
Genzyme Corporation
Craig S. Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
2-acylaminopropoanol-type glucosylceramide synthase inhibitors
Patent number
9,744,153
Issue date
Aug 29, 2017
Genzyme Corporation
Craig Siegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
2-acylaminopropoanol-type glucosylceramide synthase inhibitors
Patent number
9,745,294
Issue date
Aug 29, 2017
Genzyme Corporation
Craig Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Method of preparing glucosylceramide synthase inhibitors
Patent number
9,682,975
Issue date
Jun 20, 2017
Genzyme Corporation
Craig S. Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyl transferase in...
Patent number
9,546,161
Issue date
Jan 17, 2017
Genzyme Corporation
Bradford H. Hirth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Salt forms of (S)-quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-...
Patent number
9,518,049
Issue date
Dec 13, 2016
Genzyme Corporation
Craig S. Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
2-acylaminopropoanol-type glucosylceramide synthase inhibitors
Patent number
9,272,996
Issue date
Mar 1, 2016
Genzyme Corporation
Craig Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
2-acylaminopropoanol-type glucosylceramide synthase inhibitors
Patent number
8,940,776
Issue date
Jan 27, 2015
Genzyme Corporation
Craig Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Synthesis of UDP-Glucose: N-acylsphingosine glucosyl transferase in...
Patent number
8,779,163
Issue date
Jul 15, 2014
Genzyme Corporation
Bradford H. Hirth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
2-acylaminopropoanol-type glucosylceramide synthase inhibitors
Patent number
8,309,593
Issue date
Nov 13, 2012
Genzyme Corporation
Craig Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
2-acylaminopropoanol-type glucosylceramide synthase inhibitors
Patent number
8,304,447
Issue date
Nov 6, 2012
Genzyme Corporation
Craig Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
Patent number
8,138,353
Issue date
Mar 20, 2012
Genzyme Corporation
Bradford H. Hirth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
Patent number
7,763,738
Issue date
Jul 27, 2010
Genzyme Corporation
Bradford H. Hirth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
Patent number
7,615,573
Issue date
Nov 10, 2009
The Regents of the University of Michigan
Craig Siegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
Patent number
7,265,228
Issue date
Sep 4, 2007
Genzyme Corporation
Bradford H. Hirth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Amino ceramide-like compounds and therapeutic methods of use
Patent number
7,253,185
Issue date
Aug 7, 2007
The Regents of the University of Michigan
James A. Shayman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
Patent number
7,196,205
Issue date
Mar 27, 2007
The Regents of the University of Michigan
Craig Siegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Amino ceramide-like compounds and therapeutic methods of use
Patent number
6,916,802
Issue date
Jul 12, 2005
Genzyme Corporation
James A. Shayman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
Patent number
6,855,830
Issue date
Feb 15, 2005
Genzyme Corporation
Bradford H. Hirth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Cationic amphiphiles for intracellular delivery of therapeutic mole...
Patent number
6,383,814
Issue date
May 7, 2002
Genzyme Corporation
Edward R. Lee
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Organ-specific targeting of cationic amphiphile / DNA complexes for...
Patent number
6,331,524
Issue date
Dec 18, 2001
Genzyme Corporation
Ronald K. Scheule
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Organ-specific targeting of cationic amphiphile/DNA complexes for g...
Patent number
6,071,890
Issue date
Jun 6, 2000
Genzyme Corporation
Ronald K. Scheule
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Cationic amphiphiles containing multiplesteroid lipophilic groups
Patent number
5,952,516
Issue date
Sep 14, 1999
Genzyme Corporation
Craig S. Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Cationic amphiphiles containing linkers derived from neutral or pos...
Patent number
5,948,925
Issue date
Sep 7, 1999
Genzyme Corporation
Mikaela N. Keynes
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Cationic amphiphile/DNA complexes
Patent number
5,948,767
Issue date
Sep 7, 1999
Genzyme Corporation
Ronald K. Scheule
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Cationic amphiphiles for cell transfections
Patent number
5,942,634
Issue date
Aug 24, 1999
Genzyme Corporation
Craig S. Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Cationic amphiphile compositions for intracellular delivery of ther...
Patent number
5,939,401
Issue date
Aug 17, 1999
Genzyme Corporation
John Marshall
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE
Publication number
20230172903
Publication date
Jun 8, 2023
Genzyme Corporation
Hanlan LIU
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE
Publication number
20210393590
Publication date
Dec 23, 2021
Genzyme Corporation
Hanlan Liu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE
Publication number
20210369672
Publication date
Dec 2, 2021
Genzyme Corporation
Hanlan Liu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...
Publication number
20210171507
Publication date
Jun 10, 2021
Genzyme Corporation
Bradford H. Hirth
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHOD OF PREPARING GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
Publication number
20200181137
Publication date
Jun 11, 2020
Genzyme Corporation
Craig S. SIEGEL
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...
Publication number
20190322649
Publication date
Oct 24, 2019
Genzyme Corporation
Bradford H. Hirth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHOD OF PREPARING GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
Publication number
20190031652
Publication date
Jan 31, 2019
Genzyme Corporation
Craig S. SIEGEL
C07 - ORGANIC CHEMISTRY
Information
Patent Application
2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors
Publication number
20180093981
Publication date
Apr 5, 2018
Genzyme Corporation
Craig Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...
Publication number
20170334888
Publication date
Nov 23, 2017
Genzyme Corporation
Bradford H. Hirth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHOD OF PREPARING GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
Publication number
20170334903
Publication date
Nov 23, 2017
Genzyme Corporation
Craig S. SIEGEL
C07 - ORGANIC CHEMISTRY
Information
Patent Application
2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors
Publication number
20160338996
Publication date
Nov 24, 2016
Genzyme Corporation
Craig Siegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
INHIBITOR OF GLUCOSYLCERAMIDE SYNTHASE
Publication number
20160166542
Publication date
Jun 16, 2016
Genzyme Corporation
Hanlan Liu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
AMORPHOUS AND A CRYSTALLINE FORM OF GENZ 112638 HEMITARTRATE AS INH...
Publication number
20160120842
Publication date
May 5, 2016
Genzyme Corporation
Hanlan Liu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHOD OF PREPARING GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
Publication number
20160039806
Publication date
Feb 11, 2016
Genzyme Corporation
Craig S. SIEGEL
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SALT FORMS OF (S)-QUINUCLIDIN-3-YL (2-(2-(4-FLUOROPHENYL)THIAZOL-4-...
Publication number
20160039805
Publication date
Feb 11, 2016
Genzyme Corporation
Craig S. SIEGEL
C07 - ORGANIC CHEMISTRY
Information
Patent Application
2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors
Publication number
20150225393
Publication date
Aug 13, 2015
Genzyme Corporation
Craig Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYL TRANSFERASE IN...
Publication number
20150148534
Publication date
May 28, 2015
Bradford H. Hirth
C07 - ORGANIC CHEMISTRY
Information
Patent Application
AMORPHOUS AND A CRYSTALLINE FORM OF GENZ 112638 HEMITARTRATE AS INH...
Publication number
20130137743
Publication date
May 30, 2013
Genzyme Corporation
Hanlan Liu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
Publication number
20120322786
Publication date
Dec 20, 2012
Genzyme Corporation
Craig Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Application
2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
Publication number
20120322787
Publication date
Dec 20, 2012
Genzyme Corporation
Craig Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYL TRANSFERASE IN...
Publication number
20120296088
Publication date
Nov 22, 2012
Genzyme Corporation
Bradford H. Hirth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors
Publication number
20110184021
Publication date
Jul 28, 2011
Craig Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...
Publication number
20110003987
Publication date
Jan 6, 2011
Genzyme Corporation
Bradford H. Hirth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS
Publication number
20100256216
Publication date
Oct 7, 2010
Craig Siegel
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Amino ceramide-like compounds and therapeutic methods of use
Publication number
20090312392
Publication date
Dec 17, 2009
James A. Shayman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Amino ceramide-like compounds and therapeutic methods of use
Publication number
20080146533
Publication date
Jun 19, 2008
James A. Shayman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SYNTHESIS OF UDP-GLUCOSE: N-ACYLSPHINGOSINE GLUCOSYLTRANSFERASE INH...
Publication number
20080058514
Publication date
Mar 6, 2008
Bradford H. Hirth
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
Publication number
20070203223
Publication date
Aug 30, 2007
Craig Siegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Amino ceramide-like compounds and therapeutic methods of use
Publication number
20050267094
Publication date
Dec 1, 2005
The Regents of the University of Michigan
James A. Shayman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inh...
Publication number
20050222244
Publication date
Oct 6, 2005
Genzyme Corporation
Craig Siegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE