Darrell J. IRVINE

Person

Arlington, MA, US

People

Patents Grantslast 30 patents

Information Patent Grant
Control of replication and transcription of self-replicating RNA in...
- Patent number 12,139,721
- Issue date Nov 12, 2024
- Massachusetts Institute of Technology
- Darrell J. Irvine
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Peptide nucleic acid functionalized hydrogel microneedles for sampl...
- Patent number 12,018,315
- Issue date Jun 25, 2024
- Massachusetts Institute of Technology
- Darrell J. Irvine
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for heterologous repRNA immunizations
- Patent number 11,964,007
- Issue date Apr 23, 2024
- Janssen Vaccines & Prevention B.V.
- Ronald Vogels
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
- Patent number 11,964,026
- Issue date Apr 23, 2024
- Massachusetts Institute of Technology
- Antonio Eric Barberio
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Synthetic oncolytic LNP-replicon RNA and uses for cancer immunotherapy
- Patent number 11,717,548
- Issue date Aug 8, 2023
- Massachusetts Institute of Technology
- Darrell J. Irvine
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Immunomodulatory fusion protein-metal hydroxide complexes and metho...
- Patent number 11,642,409
- Issue date May 9, 2023
- Massachusetts Insttute of Technology
- Darrell J. Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Albumin binding peptide conjugates and methods thereof
- Patent number 11,642,416
- Issue date May 9, 2023
- Massachusetts Institute of Technology
- Kelly Dare Moynihan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Nanoparticle vaccine adjuvant and methods of use thereof
- Patent number 11,547,672
- Issue date Jan 10, 2023
- Massachusetts Institute of Technology
- Darrell J. Irvine
- B82 - NANO-TECHNOLOGY
Information Patent Grant
Carrier-free biologically-active protein nanostructures
- Patent number 11,529,392
- Issue date Dec 20, 2022
- Massachusetts Institute of Technology
- Li Tang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods to specifically profile protease activity at lymph nodes
- Patent number 11,448,643
- Issue date Sep 20, 2022
- Massachusetts Institute of Technology
- Sangeeta N. Bhatia
- B82 - NANO-TECHNOLOGY
Information Patent Grant
Nucleic acid nanostructure platform for antigen presentation and va...
- Patent number 11,419,932
- Issue date Aug 23, 2022
- Massachusetts Institute of Technology
- Mark Bathe
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
- Patent number 11,419,947
- Issue date Aug 23, 2022
- Massachusetts Institute of Technology
- Antonio Eric Barberio
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
RNA-based logic circuits with RNA binding proteins, aptamers and sm...
- Patent number 11,351,271
- Issue date Jun 7, 2022
- Massachusetts Institute of Technology
- Ron Weiss
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cell surface coupling of nanoparticles
- Patent number 11,261,226
- Issue date Mar 1, 2022
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY (MITN1)
- Darrell J. Irvine
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Combination immunotherapy dosing regimen for immune checkpoint bloc...
- Patent number 11,235,032
- Issue date Feb 1, 2022
- Massachusetts Institute of Technology
- Chensu Wang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods and compositions for heterologous repRNA immunizations
- Patent number 11,235,051
- Issue date Feb 1, 2022
- Janssen Vaccines & Prevention B.V.
- Ronald Vogels
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antigen-adjuvant coupling reagents and methods of use
- Patent number 11,224,648
- Issue date Jan 18, 2022
- Massachusetts Institute of Technology
- Darrell J. Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Synthetic nanoparticles for delivery of immunomodulatory compounds
- Patent number 11,207,418
- Issue date Dec 28, 2021
- Massachusetts Institute of Technology
- Darrell J. Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Delivery of biomolecules to immune cells
- Patent number 11,111,472
- Issue date Sep 7, 2021
- Massachusetts Institute of Technology
- Armon R. Sharei
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Albumin binding peptide conjugates and methods thereof
- Patent number 11,077,199
- Issue date Aug 3, 2021
- Massachusetts Institute of Technology
- Kelly Dare Moynihan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Cell surface coupling of nanoparticles
- Patent number 11,034,752
- Issue date Jun 15, 2021
- Massachusetts Institute of Technology
- Darrell J. Irvine
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Lipid nanoparticles and use thereof to deliver RNA polynucleotides
- Patent number 11,026,894
- Issue date Jun 8, 2021
- Massachusetts Institute of Technology
- Darrell J. Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Immunostimulatory compositions and methods of use thereof
- Patent number 10,953,105
- Issue date Mar 23, 2021
- Massachusetts Institute of Technology
- Darrell Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treating cancer cells expressing tumor-associated integrins
- Patent number 10,888,603
- Issue date Jan 12, 2021
- The Board of Trustees of the Leland Stanford Junior University
- Karl Dane Wittrup
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Carrier-free biologically-active protein nanostructures
- Patent number 10,588,942
- Issue date Mar 17, 2020
- Massachusetts Institute of Technology
- Li Tang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Carrier-free biologically-active protein nanostructures
- Patent number 10,357,544
- Issue date Jul 23, 2019
- Massachusetts Institute of Technology
- Li Tang
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Synthetic nanoparticles for delivery of immunomodulatory compounds
- Patent number 10,300,145
- Issue date May 28, 2019
- Massachusetts Institute of Technology
- Darrell J. Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Carrier-free biologically-active protein nanostructures
- Patent number 10,226,510
- Issue date Mar 12, 2019
- Massachusetts Institute of Technology
- Li Tang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Immunostimulatory compositions and methods of use thereof
- Patent number 10,029,016
- Issue date Jul 24, 2018
- Massachusetts Insitute of Technology
- Darrell Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Lipid vesicle compositions and methods of use
- Patent number 9,907,753
- Issue date Mar 6, 2018
- Massachusetts Institute of Technology
- Darrell J. Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
COMPOSITIONS FOR CHIMERIC ANTIGEN RECEPTOR T CELL THERAPY AND USES...
- Publication number 20240082373
- Publication date Mar 14, 2024
- Massachusetts Institute of Technology
- Darrell J. IRVINE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYNTHETIC ONCOLYTIC LNP-REPLICON RNA AND USES FOR CANCER IMMUNOTHERAPY
- Publication number 20240024394
- Publication date Jan 25, 2024
- Massachusetts Institute of Technology
- Darrell J. Irvine
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TRANSMUCOSAL AMPHIPHILE-PROTEIN CONJUGATE VACCINE
- Publication number 20230414763
- Publication date Dec 28, 2023
- Massachusetts Institute of Technology
- Darrell J. Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CAR CELLS TARGETING AN INSERTED LIGAND
- Publication number 20230372395
- Publication date Nov 23, 2023
- Massachusetts Institute of Technology
- Darrell J. Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NUCLEIC ACID NANOSTRUCTURE PLATFORM FOR PROGRAMMING IMMUNE STIMULATION
- Publication number 20230330219
- Publication date Oct 19, 2023
- Massachusetts Institute of Technology
- Mark Bathe
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
IMMUNOMODULATORY FUSION PROTEIN-METAL HYDROXIDE COMPLEXES AND METHO...
- Publication number 20230302128
- Publication date Sep 28, 2023
- Massachusetts Institute of Technology
- Darrell J. IRVINE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CARRIER-FREE BIOLOGICALLY-ACTIVE PROTEIN NANOSTRUCTURES
- Publication number 20230277626
- Publication date Sep 7, 2023
- Massachusetts Institute of Technology
- Li TANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ALBUMIN BINDING PEPTIDE CONJUGATES AND METHODS THEREOF
- Publication number 20230248840
- Publication date Aug 10, 2023
- Massachusetts Institute of Technology
- Kelly Dare MOYNIHAN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PEPTIDE NUCLEIC ACID FUNCTIONALIZED HYDROGEL MICRONEEDLES FOR SAMPL...
- Publication number 20230242969
- Publication date Aug 3, 2023
- Massachusetts Institute of Technology
- Darrell J. Irvine
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LAYER-BY-LAYER NANOPARTICLES FOR CYTOKINE THERAPY IN CANCER TREATMENT
- Publication number 20230201367
- Publication date Jun 29, 2023
- Massachusetts Institute of Technology
- Antonio E. Barberio
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR LONG-LASTING GERMINAL CENTER RESPONSES...
- Publication number 20230190920
- Publication date Jun 22, 2023
- Massachusetts Institute of Technology
- Darrell Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NANOPARTICLE VACCINE ADJUVANT AND METHODS OF USE THEREOF
- Publication number 20230157967
- Publication date May 25, 2023
- Massachusetts Institute of Technology
- Darrell J. Irvine
- B82 - NANO-TECHNOLOGY
Information Patent Application
LIPID COMPOSITIONS FOR DELIVERY OF STING AGONIST COMPOUNDS AND USES...
- Publication number 20230149560
- Publication date May 18, 2023
- Massachusetts Institute of Technology
- Darrell J. IRVINE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Synergistic Combination of Alum and Non-Liposome, Non-Micelle Parti...
- Publication number 20230109193
- Publication date Apr 6, 2023
- Massachusetts Institute of Technology
- Darrell Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Engineered Alum-binding SARS-CoV-2 Immunogens
- Publication number 20230104171
- Publication date Apr 6, 2023
- Massachusetts Institute of Technology
- Kristen Alexandra Rodrigues
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS TO SPECIFICALLY PROFILE PROTEASE ACTIVITY AT LYMPH NODES
- Publication number 20230040528
- Publication date Feb 9, 2023
- Massachusetts Institute of Technology
- Sangeeta N. Bhatia
- B82 - NANO-TECHNOLOGY
Information Patent Application
RNA-BASED LOGIC CIRCUITS WITH RNA BINDING PROTEINS, APTAMERS AND SM...
- Publication number 20220395585
- Publication date Dec 15, 2022
- Massachusetts Institute of Technology
- Ron Weiss
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
FUSION POLYPEPTIDES
- Publication number 20220372495
- Publication date Nov 24, 2022
- Ankyra Therapeutics, Inc.
- Michael Schmidt
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SOLUBLE MULTIMERIC IMMUNOGLOBULIN-SCAFFOLD BASED FUSION PROTEINS AN...
- Publication number 20220275043
- Publication date Sep 1, 2022
- Darrell J. IRVINE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
IN VIVO TARGETING OF CELLS WITH LIGAND-CONJUGATED PARTICLES
- Publication number 20220251160
- Publication date Aug 11, 2022
- Massachusetts Institute of Technology
- Darrell J. IRVINE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CELL SURFACE COUPLING OF NANOPARTICLES
- Publication number 20220185860
- Publication date Jun 16, 2022
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY (MITN1)
- Darrell J. IRVINE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Methods and Compositions for Heterologous repRNA Immunizations
- Publication number 20220111033
- Publication date Apr 14, 2022
- Janssen Vaccines & Prevention B.V.
- Ronald Vogels
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMBINATION IMMUNOTHERAPY DOSING REGIMEN FOR IMMUNE CHECKPOINT BLOC...
- Publication number 20220096601
- Publication date Mar 31, 2022
- Massachusetts Institute of Technology
- Chensu WANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DELIVERY OF BIOMOLECULES TO IMMUNE CELLS
- Publication number 20220064584
- Publication date Mar 3, 2022
- Massachusetts Institute of Technology
- Armon R. Sharei
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
FERRITIN NANOPARTICLE DISPLAYING AN HIV TRIMER
- Publication number 20210363194
- Publication date Nov 25, 2021
- International AIDS Vaccine Initiative
- Talar Tokatlian
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS...
- Publication number 20210340524
- Publication date Nov 4, 2021
- Massachusetts Institute of Technology
- Darrell J. IRVINE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF
- Publication number 20210338833
- Publication date Nov 4, 2021
- Massachusetts Institute of Technology
- Darrell J. IRVINE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ALBUMIN BINDING PEPTIDE CONJUGATES AND METHODS THEREOF
- Publication number 20210330800
- Publication date Oct 28, 2021
- Massachusetts Institute of Technology
- Kelly Dare MOYNIHAN
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CONTROL OF REPLICATION AND TRANSCRIPTION OF SELF-REPLICATING RNA IN...
- Publication number 20210324413
- Publication date Oct 21, 2021
- Massachusetts Institute of Technology
- Darrell J. Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
HIV-1 SPECIFIC IMMUNOGEN COMPOSITIONS AND METHODS OF USE
- Publication number 20210317192
- Publication date Oct 14, 2021
- Massachusetts Institute of Technology
- Darrell J. Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Darrell J. IRVINE

Person

Patents Grantslast 30 patents

Control of replication and transcription of self-replicating RNA in...

Peptide nucleic acid functionalized hydrogel microneedles for sampl...

Methods and compositions for heterologous repRNA immunizations

Layer-by-layer nanoparticles for cytokine therapy in cancer treatment

Synthetic oncolytic LNP-replicon RNA and uses for cancer immunotherapy

Immunomodulatory fusion protein-metal hydroxide complexes and metho...

Albumin binding peptide conjugates and methods thereof

Nanoparticle vaccine adjuvant and methods of use thereof

Carrier-free biologically-active protein nanostructures

Methods to specifically profile protease activity at lymph nodes

Nucleic acid nanostructure platform for antigen presentation and va...

Layer-by-layer nanoparticles for cytokine therapy in cancer treatment

RNA-based logic circuits with RNA binding proteins, aptamers and sm...

Cell surface coupling of nanoparticles

Combination immunotherapy dosing regimen for immune checkpoint bloc...

Methods and compositions for heterologous repRNA immunizations

Antigen-adjuvant coupling reagents and methods of use

Synthetic nanoparticles for delivery of immunomodulatory compounds

Delivery of biomolecules to immune cells

Albumin binding peptide conjugates and methods thereof

Cell surface coupling of nanoparticles

Lipid nanoparticles and use thereof to deliver RNA polynucleotides

Immunostimulatory compositions and methods of use thereof

Methods of treating cancer cells expressing tumor-associated integrins

Carrier-free biologically-active protein nanostructures

Carrier-free biologically-active protein nanostructures

Synthetic nanoparticles for delivery of immunomodulatory compounds

Carrier-free biologically-active protein nanostructures

Immunostimulatory compositions and methods of use thereof

Lipid vesicle compositions and methods of use

Patents Applicationslast 30 patents

COMPOSITIONS FOR CHIMERIC ANTIGEN RECEPTOR T CELL THERAPY AND USES...

SYNTHETIC ONCOLYTIC LNP-REPLICON RNA AND USES FOR CANCER IMMUNOTHERAPY

TRANSMUCOSAL AMPHIPHILE-PROTEIN CONJUGATE VACCINE

CAR CELLS TARGETING AN INSERTED LIGAND

NUCLEIC ACID NANOSTRUCTURE PLATFORM FOR PROGRAMMING IMMUNE STIMULATION

IMMUNOMODULATORY FUSION PROTEIN-METAL HYDROXIDE COMPLEXES AND METHO...

CARRIER-FREE BIOLOGICALLY-ACTIVE PROTEIN NANOSTRUCTURES

ALBUMIN BINDING PEPTIDE CONJUGATES AND METHODS THEREOF

PEPTIDE NUCLEIC ACID FUNCTIONALIZED HYDROGEL MICRONEEDLES FOR SAMPL...

LAYER-BY-LAYER NANOPARTICLES FOR CYTOKINE THERAPY IN CANCER TREATMENT

COMPOSITIONS AND METHODS FOR LONG-LASTING GERMINAL CENTER RESPONSES...

NANOPARTICLE VACCINE ADJUVANT AND METHODS OF USE THEREOF

LIPID COMPOSITIONS FOR DELIVERY OF STING AGONIST COMPOUNDS AND USES...

Synergistic Combination of Alum and Non-Liposome, Non-Micelle Parti...

Engineered Alum-binding SARS-CoV-2 Immunogens

METHODS TO SPECIFICALLY PROFILE PROTEASE ACTIVITY AT LYMPH NODES

RNA-BASED LOGIC CIRCUITS WITH RNA BINDING PROTEINS, APTAMERS AND SM...

FUSION POLYPEPTIDES

SOLUBLE MULTIMERIC IMMUNOGLOBULIN-SCAFFOLD BASED FUSION PROTEINS AN...

IN VIVO TARGETING OF CELLS WITH LIGAND-CONJUGATED PARTICLES

CELL SURFACE COUPLING OF NANOPARTICLES

Methods and Compositions for Heterologous repRNA Immunizations

COMBINATION IMMUNOTHERAPY DOSING REGIMEN FOR IMMUNE CHECKPOINT BLOC...

DELIVERY OF BIOMOLECULES TO IMMUNE CELLS

FERRITIN NANOPARTICLE DISPLAYING AN HIV TRIMER

METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS...

CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF

ALBUMIN BINDING PEPTIDE CONJUGATES AND METHODS THEREOF

CONTROL OF REPLICATION AND TRANSCRIPTION OF SELF-REPLICATING RNA IN...

HIV-1 SPECIFIC IMMUNOGEN COMPOSITIONS AND METHODS OF USE