David Spiegel

Person

New Haven, CT, US

People

Patents Grantslast 30 patents

Information Patent Grant
Reprogramming urokinase into an antibody-recruiting anticancer agent
- Patent number 12,312,621
- Issue date May 27, 2025
- Yale University
- David A. Spiegel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Molecular degraders of extracellular proteins
- Patent number 12,234,256
- Issue date Feb 25, 2025
- Yale University
- David Caianiello
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Therapeutic DNP derivatives and methods using same
- Patent number 12,168,639
- Issue date Dec 17, 2024
- Yale University
- Gerald I. Shulman
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
CD16a binding agents and uses thereof
- Patent number 12,162,892
- Issue date Dec 10, 2024
- KLEO PHARMACEUTICALS, INC.
- Anna Bunin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Molecular degraders of extracellular proteins
- Patent number 12,128,105
- Issue date Oct 29, 2024
- Yale University
- David Caianiello
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bi-functional molecules to degrade circulating proteins
- Patent number 12,083,181
- Issue date Sep 10, 2024
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Chimeric small molecules for the recruitment of antibodies to cance...
- Patent number 12,084,517
- Issue date Sep 10, 2024
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Decarboxylated cannabis compositions and methods of making the same
- Patent number 12,070,479
- Issue date Aug 27, 2024
- PT WORLDWIDE
- Alexander John Levine
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Grant
Synthetic antibody mimetic compounds (SYAMS) targeting cancer, espe...
- Patent number 12,042,542
- Issue date Jul 23, 2024
- Yale University
- David A. Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Reprogramming urokinase into an antibody-recruiting anticancer agent
- Patent number 11,920,172
- Issue date Mar 5, 2024
- Yale University
- David A. Spiegel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bifunctional molecules with antibody-recruiting and entry inhibitor...
- Patent number 11,858,917
- Issue date Jan 2, 2024
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bi-functional molecules to degrade circulating proteins
- Patent number 11,767,301
- Issue date Sep 26, 2023
- Yale University
- David Spiegel
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Chimeric small molecules for the recruitment of antibodies to cance...
- Patent number 11,725,064
- Issue date Aug 15, 2023
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Therapeutic DNP derivatives and methods using same
- Patent number 11,597,697
- Issue date Mar 7, 2023
- Yale University
- Gerald I. Shulman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
CD16A binding agents and uses thereof
- Patent number 11,572,370
- Issue date Feb 7, 2023
- Biohaven Therapeutics Ltd.
- Anna Bunin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Therapeutic DNP derivatives and methods using same
- Patent number 11,472,764
- Issue date Oct 18, 2022
- Yale University
- Gerald I. Shulman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bifunctional molecules with antibody-recruiting and entry inhibitor...
- Patent number 11,136,316
- Issue date Oct 5, 2021
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Chimeric small molecules for the recruitment of antibodies to cance...
- Patent number 11,014,992
- Issue date May 25, 2021
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Reprogramming urokinase into an antibody-recruiting anticancer agent
- Patent number 10,961,527
- Issue date Mar 30, 2021
- Yale University
- David A. Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Synthetic antibody mimetic compounds (SyAMs) targeting cancer, espe...
- Patent number 10,912,836
- Issue date Feb 9, 2021
- Yale University
- David A. Spiegel
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Therapeutic DNP derivatives and methods using same
- Patent number 10,781,161
- Issue date Sep 22, 2020
- Yale University
- Gerald I. Shulman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody-recruiting molecules for the treatment of cancer
- Patent number 10,780,084
- Issue date Sep 22, 2020
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Chimeric small molecules for the recruitment of antibodies to cance...
- Patent number 10,703,823
- Issue date Jul 7, 2020
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bifunctional molecules with antibody-recruiting and entry inhibitor...
- Patent number 10,703,743
- Issue date Jul 7, 2020
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Small molecule based antibody-recruiting compounds for cancer treat...
- Patent number 10,633,374
- Issue date Apr 28, 2020
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Substituted glucosepanes and compositions thereof
- Patent number 10,526,339
- Issue date Jan 7, 2020
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Therapeutic DNP derivatives and methods using same
- Patent number 10,457,629
- Issue date Oct 29, 2019
- Yale University
- Gerald I. Shulman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bifunctional molecules with antibody-recruiting and entry inhibitor...
- Patent number 10,188,727
- Issue date Jan 29, 2019
- Yale University
- David Spiegel
- B82 - NANO-TECHNOLOGY
Information Patent Grant
Synthetic antibody mimetic compounds (SYAMS) targeting cancer, espe...
- Patent number 10,117,943
- Issue date Nov 6, 2018
- Yale University
- David A. Spiegel
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Chimeric small molecules for the recruitment of antibodies to cance...
- Patent number 10,066,026
- Issue date Sep 4, 2018
- Yale University
- David Spiegel
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
BI-FUNCTIONAL MOLECULES TO DEGRADE CIRCULATING PROTEINS
- Publication number 20250205343
- Publication date Jun 26, 2025
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS
- Publication number 20250161460
- Publication date May 22, 2025
- Yale University
- David CAIANIELLO
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ENGINEERED ANTIBODIES AS MOLECULAR DEGRADERS THROUGH CELLULAR RECEP...
- Publication number 20240342293
- Publication date Oct 17, 2024
- Yale University
- David SPIEGEL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BIFUNCTIONAL DEGRADERS OF GALACTOSE-DEFICIENT IMMUNOGLOBULINS
- Publication number 20240309114
- Publication date Sep 19, 2024
- BIOHAVEN THERAPEUTICS LTD.
- Gene M. DUBOWCHIK
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
AGENTS FOR DIRECTED CONJUGATION TECHNIQUES AND CONJUGATED PRODUCTS
- Publication number 20240252674
- Publication date Aug 1, 2024
- BIOHAVEN THERAPEUTICS LTD.
- Wieslaw KAZMIERSKI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME
- Publication number 20240181067
- Publication date Jun 6, 2024
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TARGETED BIFUNCTIONAL DEGRADERS
- Publication number 20240148885
- Publication date May 9, 2024
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Bi-functional Molecules To Degrade Circulating Proteins
- Publication number 20240083859
- Publication date Mar 14, 2024
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
REPROGRAMMING UROKINASE INTO AN ANTIBODY-RECRUITING ANTICANCER AGENT
- Publication number 20240067952
- Publication date Feb 29, 2024
- Yale University
- David A. Spiegel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCE...
- Publication number 20240067756
- Publication date Feb 29, 2024
- Yale University
- David Spiegel
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BI-FUNCTIONAL MOLECULES TO DEGRADE CIRCULATING PROTEINS
- Publication number 20240050578
- Publication date Feb 15, 2024
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CD16A BINDING AGENTS AND USES THEREOF
- Publication number 20240051966
- Publication date Feb 15, 2024
- KLEO PHARMACEUTICALS, INC.
- Anna Bunin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
THERAPEUTIC DNP DERIVATIVES AND METHODS USING SAME
- Publication number 20240018089
- Publication date Jan 18, 2024
- Yale University
- Gerald I. Shulman
- C07 - ORGANIC CHEMISTRY
Information Patent Application
MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS
- Publication number 20230346951
- Publication date Nov 2, 2023
- Yale University
- David CAIANIELLO
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS
- Publication number 20230330240
- Publication date Oct 19, 2023
- BIOHAVEN THERAPEUTICS LTD.
- Alexander Sergei BAYDEN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS
- Publication number 20230271994
- Publication date Aug 31, 2023
- Yale University
- David CAIANIELLO
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Bifunctional Small Molecules to Target the Selective Degradation of...
- Publication number 20230233689
- Publication date Jul 27, 2023
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SMALL MOLECULE ADAPTER REGULATED, TARGET SPECIFIC CHIMERIC ANTIGEN...
- Publication number 20230159611
- Publication date May 25, 2023
- Yale University
- David Spiegel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DIRECTED CONJUGATION TECHNOLOGIES
- Publication number 20230128688
- Publication date Apr 27, 2023
- Luca RASTELLI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Bi-functional Molecules to Degrade Circulating Proteins
- Publication number 20230097887
- Publication date Mar 30, 2023
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TARGETED BIFUNCTIONAL DEGRADERS
- Publication number 20230087994
- Publication date Mar 23, 2023
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ENGINEERED ANTIBODIES AS MOLECULAR DEGRADERS THROUGH CELLULAR RECEP...
- Publication number 20230090282
- Publication date Mar 23, 2023
- Yale University
- David SPIEGEL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Bifunctional Small Molecules to Target the Selective Degradation of...
- Publication number 20230083388
- Publication date Mar 16, 2023
- Yale University
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CD16A BINDING AGENTS AND USES THEREOF
- Publication number 20220356191
- Publication date Nov 10, 2022
- KLEO PHARMACEUTICALS, INC.
- Anna Bunin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
THERAPEUTIC DNP DERIVATIVES AND METHODS USING SAME
- Publication number 20220234989
- Publication date Jul 28, 2022
- Yale University
- Gerald I. Shulman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPE...
- Publication number 20220111060
- Publication date Apr 14, 2022
- Yale University
- David A. Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITO...
- Publication number 20220089579
- Publication date Mar 24, 2022
- Yale University
- David Spiegel
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCE...
- Publication number 20220023428
- Publication date Jan 27, 2022
- David Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
REPROGRAMMING UROKINASE INTO AN ANTIBODY-RECRUITING ANTICANCER AGENT
- Publication number 20210284988
- Publication date Sep 16, 2021
- David A. Spiegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Bifunctional Small Molecules to Target the Selective Degradation of...
- Publication number 20210145974
- Publication date May 20, 2021
- David Spiegel
- C07 - ORGANIC CHEMISTRY

David Spiegel

Person

Patents Grantslast 30 patents

Reprogramming urokinase into an antibody-recruiting anticancer agent

Molecular degraders of extracellular proteins

Therapeutic DNP derivatives and methods using same

CD16a binding agents and uses thereof

Molecular degraders of extracellular proteins

Bi-functional molecules to degrade circulating proteins

Chimeric small molecules for the recruitment of antibodies to cance...

Decarboxylated cannabis compositions and methods of making the same

Synthetic antibody mimetic compounds (SYAMS) targeting cancer, espe...

Reprogramming urokinase into an antibody-recruiting anticancer agent

Bifunctional molecules with antibody-recruiting and entry inhibitor...

Bi-functional molecules to degrade circulating proteins

Chimeric small molecules for the recruitment of antibodies to cance...

Therapeutic DNP derivatives and methods using same

CD16A binding agents and uses thereof

Therapeutic DNP derivatives and methods using same

Bifunctional molecules with antibody-recruiting and entry inhibitor...

Chimeric small molecules for the recruitment of antibodies to cance...

Reprogramming urokinase into an antibody-recruiting anticancer agent

Synthetic antibody mimetic compounds (SyAMs) targeting cancer, espe...

Therapeutic DNP derivatives and methods using same

Antibody-recruiting molecules for the treatment of cancer

Chimeric small molecules for the recruitment of antibodies to cance...

Bifunctional molecules with antibody-recruiting and entry inhibitor...

Small molecule based antibody-recruiting compounds for cancer treat...

Substituted glucosepanes and compositions thereof

Therapeutic DNP derivatives and methods using same

Bifunctional molecules with antibody-recruiting and entry inhibitor...

Synthetic antibody mimetic compounds (SYAMS) targeting cancer, espe...

Chimeric small molecules for the recruitment of antibodies to cance...

Patents Applicationslast 30 patents

BI-FUNCTIONAL MOLECULES TO DEGRADE CIRCULATING PROTEINS

MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS

ENGINEERED ANTIBODIES AS MOLECULAR DEGRADERS THROUGH CELLULAR RECEP...

BIFUNCTIONAL DEGRADERS OF GALACTOSE-DEFICIENT IMMUNOGLOBULINS

AGENTS FOR DIRECTED CONJUGATION TECHNIQUES AND CONJUGATED PRODUCTS

TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME

TARGETED BIFUNCTIONAL DEGRADERS

Bi-functional Molecules To Degrade Circulating Proteins

REPROGRAMMING UROKINASE INTO AN ANTIBODY-RECRUITING ANTICANCER AGENT

CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCE...

BI-FUNCTIONAL MOLECULES TO DEGRADE CIRCULATING PROTEINS

CD16A BINDING AGENTS AND USES THEREOF

THERAPEUTIC DNP DERIVATIVES AND METHODS USING SAME

MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS

TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS

MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS

Bifunctional Small Molecules to Target the Selective Degradation of...

SMALL MOLECULE ADAPTER REGULATED, TARGET SPECIFIC CHIMERIC ANTIGEN...

DIRECTED CONJUGATION TECHNOLOGIES

Bi-functional Molecules to Degrade Circulating Proteins

TARGETED BIFUNCTIONAL DEGRADERS

ENGINEERED ANTIBODIES AS MOLECULAR DEGRADERS THROUGH CELLULAR RECEP...

Bifunctional Small Molecules to Target the Selective Degradation of...

CD16A BINDING AGENTS AND USES THEREOF

THERAPEUTIC DNP DERIVATIVES AND METHODS USING SAME

SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPE...

BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITO...

CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCE...

REPROGRAMMING UROKINASE INTO AN ANTIBODY-RECRUITING ANTICANCER AGENT

Bifunctional Small Molecules to Target the Selective Degradation of...