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David Spiegel
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New Haven, CT, US
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Patents Grants
last 30 patents
Information
Patent Grant
Reprogramming urokinase into an antibody-recruiting anticancer agent
Patent number
11,920,172
Issue date
Mar 5, 2024
Yale University
David A. Spiegel
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Bifunctional molecules with antibody-recruiting and entry inhibitor...
Patent number
11,858,917
Issue date
Jan 2, 2024
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bi-functional molecules to degrade circulating proteins
Patent number
11,767,301
Issue date
Sep 26, 2023
Yale University
David Spiegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Chimeric small molecules for the recruitment of antibodies to cance...
Patent number
11,725,064
Issue date
Aug 15, 2023
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Therapeutic DNP derivatives and methods using same
Patent number
11,597,697
Issue date
Mar 7, 2023
Yale University
Gerald I. Shulman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
CD16A binding agents and uses thereof
Patent number
11,572,370
Issue date
Feb 7, 2023
Biohaven Therapeutics Ltd.
Anna Bunin
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Therapeutic DNP derivatives and methods using same
Patent number
11,472,764
Issue date
Oct 18, 2022
Yale University
Gerald I. Shulman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bifunctional molecules with antibody-recruiting and entry inhibitor...
Patent number
11,136,316
Issue date
Oct 5, 2021
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Chimeric small molecules for the recruitment of antibodies to cance...
Patent number
11,014,992
Issue date
May 25, 2021
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Reprogramming urokinase into an antibody-recruiting anticancer agent
Patent number
10,961,527
Issue date
Mar 30, 2021
Yale University
David A. Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Synthetic antibody mimetic compounds (SyAMs) targeting cancer, espe...
Patent number
10,912,836
Issue date
Feb 9, 2021
Yale University
David A. Spiegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Therapeutic DNP derivatives and methods using same
Patent number
10,781,161
Issue date
Sep 22, 2020
Yale University
Gerald I. Shulman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Antibody-recruiting molecules for the treatment of cancer
Patent number
10,780,084
Issue date
Sep 22, 2020
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Chimeric small molecules for the recruitment of antibodies to cance...
Patent number
10,703,823
Issue date
Jul 7, 2020
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bifunctional molecules with antibody-recruiting and entry inhibitor...
Patent number
10,703,743
Issue date
Jul 7, 2020
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Small molecule based antibody-recruiting compounds for cancer treat...
Patent number
10,633,374
Issue date
Apr 28, 2020
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted glucosepanes and compositions thereof
Patent number
10,526,339
Issue date
Jan 7, 2020
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Therapeutic DNP derivatives and methods using same
Patent number
10,457,629
Issue date
Oct 29, 2019
Yale University
Gerald I. Shulman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bifunctional molecules with antibody-recruiting and entry inhibitor...
Patent number
10,188,727
Issue date
Jan 29, 2019
Yale University
David Spiegel
B82 - NANO-TECHNOLOGY
Information
Patent Grant
Synthetic antibody mimetic compounds (SYAMS) targeting cancer, espe...
Patent number
10,117,943
Issue date
Nov 6, 2018
Yale University
David A. Spiegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Chimeric small molecules for the recruitment of antibodies to cance...
Patent number
10,066,026
Issue date
Sep 4, 2018
Yale University
David Spiegel
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Bifunctional molecules with antibody-recruiting and entry inhibitor...
Patent number
10,030,008
Issue date
Jul 24, 2018
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
TLR-agonist-conjugated antibody recruiting molecules (TLR-ARMs)
Patent number
10,016,412
Issue date
Jul 10, 2018
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Cytotoxic-drug delivering molecules targeting HIV (CDM-Hs), cytotox...
Patent number
9,745,334
Issue date
Aug 29, 2017
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Crosslink breakers for preservation of biological substances
Patent number
9,622,469
Issue date
Apr 18, 2017
David Spiegel
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Bifunctional molecules with antibody-recruiting and entry inhibitor...
Patent number
9,562,038
Issue date
Feb 7, 2017
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
TLR-agonist-conjugated antibody recruiting molecules (TLR-ARMs)
Patent number
9,556,167
Issue date
Jan 31, 2017
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Chimeric small molecules for the recruitment of antibodies to cance...
Patent number
9,296,708
Issue date
Mar 29, 2016
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bifunctional molecules with antibody-recruiting and entry inhibitor...
Patent number
9,181,224
Issue date
Nov 10, 2015
Yale University
David Spiegel
B82 - NANO-TECHNOLOGY
Information
Patent Grant
Chimeric small molecules for the recruitment of antibodies to cance...
Patent number
8,859,509
Issue date
Oct 14, 2014
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME
Publication number
20240181067
Publication date
Jun 6, 2024
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TARGETED BIFUNCTIONAL DEGRADERS
Publication number
20240148885
Publication date
May 9, 2024
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Bi-functional Molecules To Degrade Circulating Proteins
Publication number
20240083859
Publication date
Mar 14, 2024
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
REPROGRAMMING UROKINASE INTO AN ANTIBODY-RECRUITING ANTICANCER AGENT
Publication number
20240067952
Publication date
Feb 29, 2024
Yale University
David A. Spiegel
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCE...
Publication number
20240067756
Publication date
Feb 29, 2024
Yale University
David Spiegel
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CD16A BINDING AGENTS AND USES THEREOF
Publication number
20240051966
Publication date
Feb 15, 2024
KLEO PHARMACEUTICALS, INC.
Anna Bunin
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BI-FUNCTIONAL MOLECULES TO DEGRADE CIRCULATING PROTEINS
Publication number
20240050578
Publication date
Feb 15, 2024
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
THERAPEUTIC DNP DERIVATIVES AND METHODS USING SAME
Publication number
20240018089
Publication date
Jan 18, 2024
Yale University
Gerald I. Shulman
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS
Publication number
20230346951
Publication date
Nov 2, 2023
Yale University
David CAIANIELLO
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TECHNOLOGIES FOR PREVENTING OR TREATING INFECTIONS
Publication number
20230330240
Publication date
Oct 19, 2023
BIOHAVEN THERAPEUTICS LTD.
Alexander Sergei BAYDEN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS
Publication number
20230271994
Publication date
Aug 31, 2023
Yale University
David CAIANIELLO
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Bifunctional Small Molecules to Target the Selective Degradation of...
Publication number
20230233689
Publication date
Jul 27, 2023
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SMALL MOLECULE ADAPTER REGULATED, TARGET SPECIFIC CHIMERIC ANTIGEN...
Publication number
20230159611
Publication date
May 25, 2023
Yale University
David Spiegel
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DIRECTED CONJUGATION TECHNOLOGIES
Publication number
20230128688
Publication date
Apr 27, 2023
Luca RASTELLI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Bi-functional Molecules to Degrade Circulating Proteins
Publication number
20230097887
Publication date
Mar 30, 2023
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TARGETED BIFUNCTIONAL DEGRADERS
Publication number
20230087994
Publication date
Mar 23, 2023
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ENGINEERED ANTIBODIES AS MOLECULAR DEGRADERS THROUGH CELLULAR RECEP...
Publication number
20230090282
Publication date
Mar 23, 2023
Yale University
David SPIEGEL
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Bifunctional Small Molecules to Target the Selective Degradation of...
Publication number
20230083388
Publication date
Mar 16, 2023
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CD16A BINDING AGENTS AND USES THEREOF
Publication number
20220356191
Publication date
Nov 10, 2022
KLEO PHARMACEUTICALS, INC.
Anna Bunin
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
THERAPEUTIC DNP DERIVATIVES AND METHODS USING SAME
Publication number
20220234989
Publication date
Jul 28, 2022
Yale University
Gerald I. Shulman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPE...
Publication number
20220111060
Publication date
Apr 14, 2022
Yale University
David A. Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITO...
Publication number
20220089579
Publication date
Mar 24, 2022
Yale University
David Spiegel
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCE...
Publication number
20220023428
Publication date
Jan 27, 2022
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
REPROGRAMMING UROKINASE INTO AN ANTIBODY-RECRUITING ANTICANCER AGENT
Publication number
20210284988
Publication date
Sep 16, 2021
David A. Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Bifunctional Small Molecules to Target the Selective Degradation of...
Publication number
20210145974
Publication date
May 20, 2021
David Spiegel
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Bi-functional Molecules to Degrade Circulating Proteins
Publication number
20210139436
Publication date
May 13, 2021
Yale University
David Spiegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME
Publication number
20210085796
Publication date
Mar 25, 2021
Yale University
John DEACON
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITO...
Publication number
20200392121
Publication date
Dec 17, 2020
David Spiegel
C07 - ORGANIC CHEMISTRY
Information
Patent Application
UNIVERSAL ABT COMPOUNDS AND USES THEREOF
Publication number
20200390895
Publication date
Dec 17, 2020
David Adam Spiegel
C07 - ORGANIC CHEMISTRY
Information
Patent Application
THERAPEUTIC DNP DERIVATIVES AND METHODS USING SAME
Publication number
20200354306
Publication date
Nov 12, 2020
Yale University
Gerald I. Shulman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE