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Deborah L. Mortensen
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Pacifica, CA, US
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Patents Grants
last 30 patents
Information
Patent Grant
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
Patent number
11,292,796
Issue date
Apr 5, 2022
Signal Pharmaceuticals, LLC
Jan Elsner
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
Patent number
10,683,298
Issue date
Jun 16, 2020
Signal Pharmaceuticals, LLC
Jan Elsner
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
Patent number
10,167,290
Issue date
Jan 1, 2019
Signal Pharmaceuticals, LLC
Jan Elsner
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted diaminopyrimidyl compounds, compositions thereof, and m...
Patent number
9,783,505
Issue date
Oct 10, 2017
Signal Pharmaceuticals, LLC
Patrick Papa
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
Patent number
9,771,371
Issue date
Sep 26, 2017
Signal Pharmaceuticals, LLC
Jan Elsner
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a...
Patent number
9,557,338
Issue date
Jan 31, 2017
Signal Pharmaceuticals, LLC
Weiming Xu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted diaminopyrimidyl compounds, compositions thereof, and m...
Patent number
9,556,126
Issue date
Jan 31, 2017
Signal Pharmaceuticals, LLC
Patrick Papa
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Halogen substituted pyrazines as intermediates of mTOR kinase inhib...
Patent number
9,193,692
Issue date
Nov 24, 2015
Signal Pharmaceuticals, LLC
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted diaminopyrimidyl compounds, compositions thereof, and m...
Patent number
9,156,798
Issue date
Oct 13, 2015
Signal Pharmaceuticals, LLC
Sogole Bahmanyar
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a...
Patent number
9,155,736
Issue date
Oct 13, 2015
Signal Pharmaceuticals, LLC
Weiming Xu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods of synthesis and purification of heteroaryl compounds
Patent number
9,079,900
Issue date
Jul 14, 2015
Signal Pharmaceuticals, LLC
Roy L. Harris
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
Patent number
8,907,087
Issue date
Dec 9, 2014
Signal Pharmaceuticals, LLC
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods of synthesis and purification of heteroaryl compounds
Patent number
8,569,494
Issue date
Oct 29, 2013
Signal Pharmaceuticals, LLC
Roy L. Harris
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indicati...
Patent number
8,507,492
Issue date
Aug 13, 2013
Signal Pharmaceuticals, LLC
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indicati...
Patent number
8,492,381
Issue date
Jul 23, 2013
Signal Pharmaceuticals, LLC
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods of treatment using heteroaryl compounds and compositions th...
Patent number
8,383,634
Issue date
Feb 26, 2013
Signal Pharmaceuticals, LLC
Deborah Sue Mortensen
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods of treatment comprising the administration of heteroaryl co...
Patent number
8,372,976
Issue date
Feb 12, 2013
Signal Pharmaceuticals, LLC
Deborah Sue Mortensen
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Method for treating cartilage disorders
Patent number
8,110,548
Issue date
Feb 7, 2012
Genentech, Inc.
Yvonne Man-Yee Chen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indicat...
Patent number
8,110,578
Issue date
Feb 7, 2012
Signal Pharmaceuticals, LLC
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
IGF-I protein variants for treating IGFBP-1-related disorders
Patent number
8,097,587
Issue date
Jan 17, 2012
Genentech, Inc.
Yves Dubaquie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Heteroaryl compounds, compositions thereof, and methods of treatmen...
Patent number
7,981,893
Issue date
Jul 19, 2011
Signal Pharmaceuticals, LLC
Deborah Sue Mortensen
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Heteroaryl compounds, compositions thereof, and methods of treatmen...
Patent number
7,968,556
Issue date
Jun 28, 2011
Signal Pharmaceuticals, LLC
Deborah Sue Mortensen
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Article of manufacture
Patent number
7,947,650
Issue date
May 24, 2011
Genentech, Inc.
Yvonne Man-Yee Chen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Method for treating cartilage disorders
Patent number
7,423,017
Issue date
Sep 9, 2008
Genentech, Inc.
Yvonne Man-Yee Chen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods for treating clinical manifestations of GH/GF axis dysregul...
Patent number
7,105,167
Issue date
Sep 12, 2006
Genentech, Inc.
Yves Dubaquie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
Modulators of BCL6 as Ligand Directed Degraders
Publication number
20240025851
Publication date
Jan 25, 2024
Celgene Corporation
Dehua Huang
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20230119470
Publication date
Apr 20, 2023
Signal Pharmaceuticals, LLC.
Jan ELSNER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PROCESS FOR PRODUCING A T CELL COMPOSITION
Publication number
20210254000
Publication date
Aug 19, 2021
Juno Therapeutics, Inc.
Archana BRAHMANDAM
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20200262840
Publication date
Aug 20, 2020
Signal Pharmaceuticals, LLC.
Jan ELSNER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20190077806
Publication date
Mar 14, 2019
Signal Pharmaceuticals, LLC.
Jan ELSNER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20170342080
Publication date
Nov 30, 2017
Signal Pharmaceuticals, LLC.
Jan ELSNER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND M...
Publication number
20160354374
Publication date
Dec 8, 2016
Signal Pharmaceuticals, LLC.
Patrick Papa
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20160024101
Publication date
Jan 28, 2016
Signal Pharmaceuticals, LLC.
Jan ELSNER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
INHIBITION OF PHOSPHORYLATION OF PRAS40, GSK3-BETA OR P70S6K1 AS A...
Publication number
20150362505
Publication date
Dec 17, 2015
Signal Pharmaceuticals, LLC.
Weiming Xu
G01 - MEASURING TESTING
Information
Patent Application
SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND M...
Publication number
20150246890
Publication date
Sep 3, 2015
Signal Pharmaceuticals, LLC.
Sogole BAHMANYAR
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND M...
Publication number
20150175557
Publication date
Jun 25, 2015
Signal Pharmaceuticals, LLC.
Patrick Papa
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20150051397
Publication date
Feb 19, 2015
Signal Pharmaceuticals, LLC.
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS
Publication number
20140155593
Publication date
Jun 5, 2014
Signal Pharmaceuticals, LLC.
Roy L. Harris
C07 - ORGANIC CHEMISTRY
Information
Patent Application
TREATMENT OF CANCER WITH TOR KINASE INHIBITORS
Publication number
20140113904
Publication date
Apr 24, 2014
Signal Pharmaceuticals, LLC.
Deborah Mortensen
G01 - MEASURING TESTING
Information
Patent Application
INHIBITION OF PHOSPHORYLATION OF PRAS40, GSK3-BETA OR P70S6K1 AS A...
Publication number
20140113905
Publication date
Apr 24, 2014
Signal Pharmaceuticals, LLC.
Weiming Xu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20130289271
Publication date
Oct 31, 2013
Signal Pharmaceuticals, LLC.
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS
Publication number
20130245254
Publication date
Sep 19, 2013
Signal Pharmaceuticals, LLC.
Roy L. Harris
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITOR FOR ONCOLOGY INDICATI...
Publication number
20120071658
Publication date
Mar 22, 2012
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITOR FOR ONCOLOGY INDICATI...
Publication number
20120059164
Publication date
Mar 8, 2012
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHODS OF TREATMENT COMPRISING THE ADMINISTRATION OF HETEROARYL CO...
Publication number
20110245245
Publication date
Oct 6, 2011
Signal Pharmaceuticals, LLC.
Deborah Sue Mortensen
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHODS OF TREATMENT USING HETEROARYL COMPOUNDS AND COMPOSITIONS TH...
Publication number
20110224217
Publication date
Sep 15, 2011
Signal Pharmaceuticals, LLC.
Deborah Sue Mortensen
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS
Publication number
20110137028
Publication date
Jun 9, 2011
Roy L. Harris
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Protein variants
Publication number
20110003746
Publication date
Jan 6, 2011
Yves Dubaquie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCI...
Publication number
20100216781
Publication date
Aug 26, 2010
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHOD FOR TREATING CARTILAGE DISORDERS
Publication number
20100130411
Publication date
May 27, 2010
Yvonne Man-Yee Chen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Heteroaryl compounds, compositions thereof, and methods of treatmen...
Publication number
20090042890
Publication date
Feb 12, 2009
Deborah Sue Mortensen
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Heteroaryl compounds, compositions thereof, and methods of treatmen...
Publication number
20090023724
Publication date
Jan 22, 2009
Deborah Sue Mortensen
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHOD FOR TREATING CARTILAGE DISORDERS
Publication number
20090011988
Publication date
Jan 8, 2009
Yvonne Man-Yee Chen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Amino-substituted heterocycles, compositions thereof, and methods o...
Publication number
20080242694
Publication date
Oct 2, 2008
Neil R. D'Sidocky
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Method for treating cartilage disorders
Publication number
20030211992
Publication date
Nov 13, 2003
Genentech, Inc.
Yvonne Man-Yee Chen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE