Dennis Buckley

Person

Boston, MA, US

People

Patents Grantslast 30 patents

Information Patent Grant
Tunable endogenous protein degradation with heterobifunctional comp...
- Patent number 12,023,385
- Issue date Jul 2, 2024
- Dana-Farber Cancer Institute, Inc.
- Dennis Buckley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the t...
- Patent number 11,944,625
- Issue date Apr 2, 2024
- The Children's Medical Center Corporation
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 11,583,586
- Issue date Feb 21, 2023
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Degradation of protein kinases by conjugation of protein kinase inh...
- Patent number 11,578,075
- Issue date Feb 14, 2023
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Regulating chimeric antigen receptors
- Patent number 11,311,609
- Issue date Apr 26, 2022
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cyano thienotriazolodiazepines and uses thereof
- Patent number 11,306,105
- Issue date Apr 19, 2022
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Tunable endogenous protein degradation
- Patent number 11,293,023
- Issue date Apr 5, 2022
- Dana-Farber Cancer Institute, Inc.
- Dennis Buckley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Degradation of bromodomain-containing protein 9 (BRD9) by conjugati...
- Patent number 11,285,218
- Issue date Mar 29, 2022
- Dana-Farber Cancer Institute, Inc.
- Dennis Buckley
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 11,059,801
- Issue date Jul 13, 2021
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Targeted protein degradation to attenuate adoptive T-cell therapy a...
- Patent number 11,046,954
- Issue date Jun 29, 2021
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the t...
- Patent number 10,980,808
- Issue date Apr 20, 2021
- The Children's Medical Center Corporation
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Degradation of protein kinases by conjugation of protein kinase inh...
- Patent number 10,925,868
- Issue date Feb 23, 2021
- Dana-Farber Cancer Institute, Inc.
- Nathanael S. Gray
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Degradation of protein kinases by conjugation of protein kinase inh...
- Patent number 10,899,768
- Issue date Jan 26, 2021
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 10,849,980
- Issue date Dec 1, 2020
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Uses of diazepane derivatives
- Patent number 10,793,571
- Issue date Oct 6, 2020
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Degradation of tripartite motif-containing protein 24 (TRIM24) by c...
- Patent number 10,702,504
- Issue date Jul 7, 2020
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 10,669,253
- Issue date Jun 2, 2020
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 10,464,925
- Issue date Nov 5, 2019
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Diazepane derivatives and uses thereof
- Patent number 10,308,653
- Issue date Jun 4, 2019
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Targeted protein degradation using a mutant E3 ubiquitin ligase
- Patent number 10,239,888
- Issue date Mar 26, 2019
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 10,125,114
- Issue date Nov 13, 2018
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Dihydropteridinone derivatives and uses thereof
- Patent number 9,951,074
- Issue date Apr 24, 2018
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 9,821,068
- Issue date Nov 21, 2017
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 9,770,512
- Issue date Sep 26, 2017
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 9,750,816
- Issue date Sep 5, 2017
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 9,694,084
- Issue date Jul 4, 2017
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Diazepane derivatives and uses thereof
- Patent number 9,695,172
- Issue date Jul 4, 2017
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE T...
- Publication number 20240342173
- Publication date Oct 17, 2024
- The Children's Medical Center Corporation
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...
- Publication number 20230131952
- Publication date Apr 27, 2023
- Dana-Farber Cancer Institute, Inc.
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TUNABLE ENDOGENOUS PROTEIN DEGRADATION
- Publication number 20220135967
- Publication date May 5, 2022
- Dana-Farber Cancer Institute, Inc.
- Dennis Buckley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SMALL MOLECULE DEGRADERS OF FKBP12 VIA RECRUITMENT OF VON HIPPEL-LI...
- Publication number 20220089589
- Publication date Mar 24, 2022
- Dana-Farber Cancer Institute, Inc.
- Nathanael S. Gray
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE T...
- Publication number 20220008420
- Publication date Jan 13, 2022
- The Children's Medical Center Corporation
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TARGETED PROTEIN DEGRADATION TO ATTENUATE ADOPTIVE T-CELL THERAPY A...
- Publication number 20210301286
- Publication date Sep 30, 2021
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF
- Publication number 20210206779
- Publication date Jul 8, 2021
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...
- Publication number 20210061811
- Publication date Mar 4, 2021
- Dana-Farber Cancer Institute, Inc.
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...
- Publication number 20210015929
- Publication date Jan 21, 2021
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...
- Publication number 20200317635
- Publication date Oct 8, 2020
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BIFUNCTIONAL MOLECULES FOR HER3 DEGRADATION AND METHODS OF USE
- Publication number 20200216454
- Publication date Jul 9, 2020
- Dana-Farber Cancer Institute, Inc.
- Nathanael S. GRAY
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF
- Publication number 20200199150
- Publication date Jun 25, 2020
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...
- Publication number 20190374528
- Publication date Dec 12, 2019
- Dana-Farber Cancer Institute, Inc.
- Nathanael S. GRAY
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TUNABLE ENDOGENOUS PROTEIN DEGRADATION WITH HETEROBIFUNCTIONAL COMP...
- Publication number 20190374657
- Publication date Dec 12, 2019
- Dana-Farber Cancer Institute, Inc.
- Dennis Buckley
- C07 - ORGANIC CHEMISTRY
Information Patent Application
REGULATING CHIMERIC ANTIGEN RECEPTORS
- Publication number 20190365875
- Publication date Dec 5, 2019
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE T...
- Publication number 20190314374
- Publication date Oct 17, 2019
- The Children's Medical Center Corporation
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...
- Publication number 20190263823
- Publication date Aug 29, 2019
- Dana-Farber Cancer Institute, Inc.
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DEGRADATION OF BROMODOMAIN-CONTAINING PROTEIN 9 (BRD9) BY CONJUGATI...
- Publication number 20190247509
- Publication date Aug 15, 2019
- Dana-Farber Cancer Institute, Inc.
- Dennis BUCKLEY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DEGRADATION OF TRIPARTITE MOTIF-CONTAINING PROTEIN 24 (TRIM24) BY C...
- Publication number 20190209535
- Publication date Jul 11, 2019
- Dana-Farber Cancer Institute, Inc.
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...
- Publication number 20190151457
- Publication date May 23, 2019
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...
- Publication number 20190071415
- Publication date Mar 7, 2019
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TARGETED PROTEIN DEGRADATION USING A MUTANT E3 UBIQUITIN LIGASE
- Publication number 20180327419
- Publication date Nov 15, 2018
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TUNABLE ENDOGENOUS PROTEIN DEGRADATION
- Publication number 20180179522
- Publication date Jun 28, 2018
- Dana-Farber Cancer Institute, Inc.
- Dennis Buckley
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TARGETED PROTEIN DEGRADATION TO ATTENUATE ADOPTIVE T-CELL THERAPY A...
- Publication number 20180169109
- Publication date Jun 21, 2018
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...
- Publication number 20180134684
- Publication date May 17, 2018
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...
- Publication number 20180085465
- Publication date Mar 29, 2018
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...
- Publication number 20180009779
- Publication date Jan 11, 2018
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
DIHYDROPTERIDINONE DERIVATIVES AND USES THEREOF
- Publication number 20170145013
- Publication date May 25, 2017
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
DIAZEPANE DERIVATIVES AND USES THEREOF
- Publication number 20170145023
- Publication date May 25, 2017
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
USES OF DIAZEPANE DERIVATIVES
- Publication number 20170008895
- Publication date Jan 12, 2017
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Dennis Buckley

Person

Patents Grantslast 30 patents

Tunable endogenous protein degradation with heterobifunctional comp...

Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the t...

Methods to induce targeted protein degradation through bifunctional...

Degradation of protein kinases by conjugation of protein kinase inh...

Regulating chimeric antigen receptors

Cyano thienotriazolodiazepines and uses thereof

Tunable endogenous protein degradation

Degradation of bromodomain-containing protein 9 (BRD9) by conjugati...

Methods to induce targeted protein degradation through bifunctional...

Targeted protein degradation to attenuate adoptive T-cell therapy a...

Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the t...

Degradation of protein kinases by conjugation of protein kinase inh...

Degradation of protein kinases by conjugation of protein kinase inh...

Methods to induce targeted protein degradation through bifunctional...

Uses of diazepane derivatives

Degradation of tripartite motif-containing protein 24 (TRIM24) by c...

Methods to induce targeted protein degradation through bifunctional...

Methods to induce targeted protein degradation through bifunctional...

Diazepane derivatives and uses thereof

Targeted protein degradation using a mutant E3 ubiquitin ligase

Methods to induce targeted protein degradation through bifunctional...

Dihydropteridinone derivatives and uses thereof

Methods to induce targeted protein degradation through bifunctional...

Methods to induce targeted protein degradation through bifunctional...

Methods to induce targeted protein degradation through bifunctional...

Methods to induce targeted protein degradation through bifunctional...

Diazepane derivatives and uses thereof

Patents Applicationslast 30 patents

CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE T...

DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...

TUNABLE ENDOGENOUS PROTEIN DEGRADATION

SMALL MOLECULE DEGRADERS OF FKBP12 VIA RECRUITMENT OF VON HIPPEL-LI...

CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE T...

TARGETED PROTEIN DEGRADATION TO ATTENUATE ADOPTIVE T-CELL THERAPY A...

CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF

DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...

METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...

METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...

BIFUNCTIONAL MOLECULES FOR HER3 DEGRADATION AND METHODS OF USE

CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF

DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...

TUNABLE ENDOGENOUS PROTEIN DEGRADATION WITH HETEROBIFUNCTIONAL COMP...

REGULATING CHIMERIC ANTIGEN RECEPTORS

CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE T...

DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...

DEGRADATION OF BROMODOMAIN-CONTAINING PROTEIN 9 (BRD9) BY CONJUGATI...

DEGRADATION OF TRIPARTITE MOTIF-CONTAINING PROTEIN 24 (TRIM24) BY C...

METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...

METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...

TARGETED PROTEIN DEGRADATION USING A MUTANT E3 UBIQUITIN LIGASE

TUNABLE ENDOGENOUS PROTEIN DEGRADATION

TARGETED PROTEIN DEGRADATION TO ATTENUATE ADOPTIVE T-CELL THERAPY A...

METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...

METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...

METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...

DIHYDROPTERIDINONE DERIVATIVES AND USES THEREOF

DIAZEPANE DERIVATIVES AND USES THEREOF

USES OF DIAZEPANE DERIVATIVES