TREA

Ivan ZLATEV

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  • Cambridge, MA, US
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Patents Grantslast 30 patents

  • Information Patent Grant

    Tunable Reversir™ compounds
    • Patent number 12,018,260
    • Issue date Jun 25, 2024
    • Alnylam Pharmaceuticals, Inc.
    • Ivan Zlatev
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Chiral control
    • Patent number 11,643,657
    • Issue date May 9, 2023
    • WAVE LIFE SCIENCES LTD.
    • David Charles Donnell Butler
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Endosomal cleavable linkers
    • Patent number 11,286,482
    • Issue date Mar 29, 2022
    • Alnylam Pharmaceuticals, Inc.
    • Jayaprakash K. Nair
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Multi-targeted single entity conjugates
    • Patent number 11,053,495
    • Issue date Jul 6, 2021
    • Alnylam Pharmaceuticals, Inc.
    • Vasant Jadhav
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Chiral design
    • Patent number 10,815,482
    • Issue date Oct 27, 2020
    • WAVE LIFE SCIENCES LTD.
    • David Butler
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Chiral control
    • Patent number 10,590,413
    • Issue date Mar 17, 2020
    • WAVE LIFE SCIENCES LTD.
    • David Charles Donnell Butler
    • C07 - ORGANIC CHEMISTRY
  • Information Patent Grant

    Chiral design
    • Patent number 10,160,969
    • Issue date Dec 25, 2018
    • WAVE LIFE SCIENCES LTD.
    • David Butler
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    5′ phosphate mimics
    • Patent number 10,131,908
    • Issue date Nov 20, 2018
    • Alnylam Pharmaceuticals, Inc.
    • Muthiah Manoharan
    • C07 - ORGANIC CHEMISTRY
  • Information Patent Grant

    RNAi agents modified at the 4′-C position
    • Patent number 10,119,136
    • Issue date Nov 6, 2018
    • Alnylam Pharmaceuticals, Inc.
    • Muthiah Manoharan
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Chiral control
    • Patent number 9,982,257
    • Issue date May 29, 2018
    • WAVE LIFE SCIENCES LTD.
    • David Butler
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Chiral control
    • Patent number 9,885,037
    • Issue date Feb 6, 2018
    • WAVE LIFE SCIENCES LTD.
    • David Butler
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    5′-end derivatives
    • Patent number 9,725,479
    • Issue date Aug 8, 2017
    • Ionis Pharmaceuticals, Inc.
    • Muthiah Manoharan
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modified 5′ diphosphate nucleosides and oligomeric compounds prepar...
    • Patent number 9,156,873
    • Issue date Oct 13, 2015
    • ISIS Pharmaceuticals, Inc.
    • Thazha P. Prakash
    • C07 - ORGANIC CHEMISTRY
  • Information Patent Grant

    Process for triphosphate oligonucleotide synthesis
    • Patent number 9,035,041
    • Issue date May 19, 2015
    • Alnylam Pharmaceuticals, Inc.
    • Ivan Zlatev
    • C07 - ORGANIC CHEMISTRY
  • Information Patent Grant

    5′ phosphate mimics
    • Patent number 8,927,513
    • Issue date Jan 6, 2015
    • Alnylam Pharmaceuticals, Inc.
    • Muthiah Manoharan
    • C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

  • Information Patent Application

    Circular siRNAs
    • Publication number 20230257745
    • Publication date Aug 17, 2023
    • Alnylam Pharmaceuticals, Inc.
    • Hartmut JAHNS
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    TUNABLE REVERSIR TM COMPOUNDS
    • Publication number 20230029227
    • Publication date Jan 26, 2023
    • Alnylam Pharmaceuticals, Inc.
    • Ivan ZLATEV
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Application

    EXTRAHEPATIC DELIVERY
    • Publication number 20230016929
    • Publication date Jan 19, 2023
    • Alnylam Pharmaceuticals, Inc.
    • Jayaprakash K. NAIR
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    REVERSIR TM COMPOUNDS
    • Publication number 20220259589
    • Publication date Aug 18, 2022
    • Alnylam Pharmaceuticals, Inc.
    • Vasant JADHAV
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    ENDOSOMAL CLEAVABLE LINKERS
    • Publication number 20220177885
    • Publication date Jun 9, 2022
    • Alnylam Pharmaceuticals, Inc.
    • Jayaprakash K. NAIR
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    REVERSIR TM COMPOUNDS
    • Publication number 20220127604
    • Publication date Apr 28, 2022
    • Alnylam Pharmaceuticals, Inc.
    • Vasant JADHAV
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    MULTI-TARGETED SINGLE ENTITY CONJUGATES
    • Publication number 20220106593
    • Publication date Apr 7, 2022
    • Alnylam Pharmaceuticals, Inc.
    • Vasant JADHAV
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Application

    CHIRAL CONTROL
    • Publication number 20210130821
    • Publication date May 6, 2021
    • WAVE LIFE SCIENCES LTD.
    • David Charles Donnell Butler
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    CHIRAL DESIGN
    • Publication number 20210115444
    • Publication date Apr 22, 2021
    • WAVE LIFE SCIENCES LTD.
    • David Butler
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    ENDOSOMAL CLEAVABLE LINKERS
    • Publication number 20190330630
    • Publication date Oct 31, 2019
    • Alnylam Pharmaceuticals, Inc.
    • Jayaprakash K. NAIR
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    CHIRAL DESIGN
    • Publication number 20190106696
    • Publication date Apr 11, 2019
    • WAVE LIFE SCIENCES LTD.
    • David Butler
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    MULTI-TARGETED SINGLE ENTITY CONJUGATES
    • Publication number 20180208927
    • Publication date Jul 26, 2018
    • Alnylam Pharmaceuticals, Inc.
    • Vasant JADHAV
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    REVERSIR TM COMPOUNDS
    • Publication number 20170369872
    • Publication date Dec 28, 2017
    • Alnylam Pharmaceuticals, Inc.
    • Vasant JADHAV
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    CHIRAL CONTROL
    • Publication number 20170275621
    • Publication date Sep 28, 2017
    • WAVE LIFE SCIENCES LTD.
    • David Charles Donnell Butler
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    CHIRAL DESIGN
    • Publication number 20170037399
    • Publication date Feb 9, 2017
    • WAVE LIFE SCIENCES LTD.
    • David Butler
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    RNAi AGENTS MODIFIED AT THE 4'-C POSITION
    • Publication number 20170029815
    • Publication date Feb 2, 2017
    • Alnylam Pharmaceuticals, Inc.
    • Muthiah MANOHARAN
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    CHIRAL CONTROL
    • Publication number 20150211006
    • Publication date Jul 30, 2015
    • WAVE LIFE SCIENCES PTE. LTD.
    • David Butler
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    5' PHOSPHATE MIMICS
    • Publication number 20150080457
    • Publication date Mar 19, 2015
    • Alnylam Pharmaceuticals, Inc.
    • Muthiah MANOHARAN
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    5'-END DERIVATIVES
    • Publication number 20130323836
    • Publication date Dec 5, 2013
    • ISIS Pharmaceuticals, Inc.
    • Muthiah Manoharan
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    CONFORMATIONALLY RESTRICTED DINUCLEOTIDE MONOMERS AND OLIGONUCLEOTIDES
    • Publication number 20130260460
    • Publication date Oct 3, 2013
    • ISIS Pharmaceuticals Inc.
    • Jeremy Lackey
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    MODIFIED 5' DIPHOSPHATE NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPAR...
    • Publication number 20130109850
    • Publication date May 2, 2013
    • ISIS Pharmaceuticals, Inc.
    • Thazha P. Prakash
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Application

    PROCESS FOR TRIPHOSPHATE OLIGONUCLEOTIDE SYNTHESIS
    • Publication number 20120220761
    • Publication date Aug 30, 2012
    • Alnylam Pharmaceuticals, Inc.
    • Ivan Zlatev
    • C07 - ORGANIC CHEMISTRY
  • Information Patent Application

    5' PHOSPHATE MIMICS
    • Publication number 20120157511
    • Publication date Jun 21, 2012
    • Alnylam Pharmaceuticals, Inc.
    • Muthiah Manoharan
    • C07 - ORGANIC CHEMISTRY
  • Information Patent Application

    SYNTHETIC METHODS AND DERIVATIVES OF TRIPHOSPHATE OLIGONUCLEOTIDES
    • Publication number 20120107272
    • Publication date May 3, 2012
    • Alnylam Pharmaceuticals, Inc.
    • Muthiah Manoharan
    • C07 - ORGANIC CHEMISTRY
  • Information Patent Application

    PROCESS FOR SYNTHESIZING OLIGONUCLEOTIDE PHOSPHATE DERIVATIVES
    • Publication number 20110282044
    • Publication date Nov 17, 2011
    • Alnylam Pharmaceuticals
    • Muthiah MANOHARAN
    • C07 - ORGANIC CHEMISTRY