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James A. Henderson
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Cambridge, MA, US
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Patents Grants
last 30 patents
Information
Patent Grant
Heterocyclic degronimers for target protein degradation
Patent number
12,076,405
Issue date
Sep 3, 2024
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Spirocyclic degronimers for target protein degradation
Patent number
12,048,748
Issue date
Jul 30, 2024
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted piperidine Degronimers for Target Protein degradation
Patent number
12,048,747
Issue date
Jul 30, 2024
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
C3-carbon linked glutarimide degronimers for target protein degrada...
Patent number
11,992,531
Issue date
May 28, 2024
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Cereblon binders for the degradation of ikaros
Patent number
11,753,397
Issue date
Sep 12, 2023
C4 Therapeutics, Inc.
James A. Henderson
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Degraders and Degrons for targeted protein degradation
Patent number
11,524,949
Issue date
Dec 13, 2022
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
N/O-linked Degrons and Degronimers for protein degradation
Patent number
11,459,335
Issue date
Oct 4, 2022
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Tricyclic degraders of Ikaros and Aiolos
Patent number
11,407,732
Issue date
Aug 9, 2022
C4 Therapeutics, Inc.
James A. Henderson
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Spirocyclic degronimers for target protein degradation
Patent number
11,185,592
Issue date
Nov 30, 2021
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Heterocyclic degronimers for target protein degradation
Patent number
10,905,768
Issue date
Feb 2, 2021
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
C3-carbon linked glutarimide degronimers for target protein degrada...
Patent number
10,849,982
Issue date
Dec 1, 2020
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Triazoles for the treatment of demyelinating dieases
Patent number
10,766,869
Issue date
Sep 8, 2020
VERTEX PHARMACEUTCALS INCORPORATED
Robert J. Davies
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Spirocyclic degronimers for target protein degradation
Patent number
10,660,968
Issue date
May 26, 2020
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Heterocyclic degronimers for target protein degradation
Patent number
10,646,575
Issue date
May 12, 2020
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Isoindolinone inhibitors of phosphatidylinositol 3-kinase
Patent number
10,183,933
Issue date
Jan 22, 2019
Vertex Pharmaceuticals Incorporated
Alex Aronov
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Triazoles for the treatment of Demyelinating Diseases
Patent number
10,118,904
Issue date
Nov 6, 2018
Vertex Pharmaceuticals Incorporated
Robert J. Davies
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Isoindolinone inhibitors of phosphatidylinositol 3-kinase
Patent number
9,676,759
Issue date
Jun 13, 2017
Vertex Pharmaceuticals Incorporated
Alex Aronov
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Analogues for the treatment or prevention of flavivirus infections
Patent number
8,779,156
Issue date
Jul 15, 2014
Vertex Pharmaceuticals Incorporated
Sanjoy Kumar Das
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Benzimidazole analogues for the treatment or prevention of flavivir...
Patent number
8,765,731
Issue date
Jul 1, 2014
Vertex Pharmaceuticals Incorporated
James A. Henderson
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Isoindolinone inhibitors of phosphatidylinositol 3-kinase
Patent number
8,466,288
Issue date
Jun 18, 2013
Vertex Pharmaceuticals Incorporated
Alex Aronov
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Benzimidazole analogues for the treatment or prevention of flavivir...
Patent number
8,354,419
Issue date
Jan 15, 2013
Vertex Pharmaceuticals Incorporated
James A. Henderson
C07 - ORGANIC CHEMISTRY
Patents Applications
last 30 patents
Information
Patent Application
COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS
Publication number
20240343733
Publication date
Oct 17, 2024
Biogen MA Inc.
Kevin M. Guckian
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY
Publication number
20240018118
Publication date
Jan 18, 2024
C 4 Therapeutics, Inc.
Christopher G. Nasveschuk
C07 - ORGANIC CHEMISTRY
Information
Patent Application
TRICYCLIC HETEROBIFUNCTIONAL COMPOUNDS FOR DEGRADATION OF TARGETED...
Publication number
20230372496
Publication date
Nov 23, 2023
C4 Therapeutics, Inc.
Christopher G. Nasveschuk
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION
Publication number
20230357180
Publication date
Nov 9, 2023
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4
Publication number
20230339902
Publication date
Oct 26, 2023
C4 Therapeutics, Inc.
Christopher G. Nasveschuk
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N/O-Linked Degrons and Degronimers for Protein Degradation
Publication number
20230279023
Publication date
Sep 7, 2023
C4 Therapeutics, Inc.
Andrew J. Phillips
G07 - CHECKING-DEVICES
Information
Patent Application
COMPOUNDS FOR TARGETED DEGRADATION OF RET
Publication number
20230233692
Publication date
Jul 27, 2023
C4 Therapeutics, Inc.
James A. Henderson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ADVANTAGEOUS THERAPIES FOR DISORDERS MEDIATED BY IKAROS OR AIOLOS
Publication number
20230190760
Publication date
Jun 22, 2023
C4 Therapeutics, Inc.
David Proia
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20230095223
Publication date
Mar 30, 2023
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TRICYCLIC DEGRADERS OF IKAROS AND AIOLOS
Publication number
20230082430
Publication date
Mar 16, 2023
C4 Therapeutics, Inc.
James A. Henderson
C07 - ORGANIC CHEMISTRY
Information
Patent Application
HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20230014124
Publication date
Jan 19, 2023
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
TARGETED PROTEIN DEGRADATION
Publication number
20220372016
Publication date
Nov 24, 2022
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADA...
Publication number
20220313826
Publication date
Oct 6, 2022
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED PIPERIDINE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20220313827
Publication date
Oct 6, 2022
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION
Publication number
20220251061
Publication date
Aug 11, 2022
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20210106688
Publication date
Apr 15, 2021
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CEREBLON BINDERS FOR THE DEGRADATION OF IKAROS
Publication number
20210009559
Publication date
Jan 14, 2021
C4 Therapeutics, Inc.
James A. Henderson
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION
Publication number
20200140456
Publication date
May 7, 2020
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
TRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES
Publication number
20190185436
Publication date
Jun 20, 2019
VERTEX PHARMACEUTICALS INCORPORATED
Robert J. Davies
C07 - ORGANIC CHEMISTRY
Information
Patent Application
AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20190076539
Publication date
Mar 14, 2019
C4 Theraprutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADA...
Publication number
20190076542
Publication date
Mar 14, 2019
C4 Theraprutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
HETEROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20190076541
Publication date
Mar 14, 2019
C4 Theraprutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20190076540
Publication date
Mar 14, 2019
C4 Theraprutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ISOINDOLINONE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE
Publication number
20170260175
Publication date
Sep 14, 2017
Vertex Pharmaceuticals Incorporated.
Alex Aronov
C07 - ORGANIC CHEMISTRY
Information
Patent Application
TRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES
Publication number
20160355488
Publication date
Dec 8, 2016
VERTEX PHARMACEUTICALS INCORPORATED
Robert J. Davies
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BENZIMIDAZOLE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIR...
Publication number
20140243257
Publication date
Aug 28, 2014
VERTEX PHARMACEUTICALS INCORPORATED
James A. Henderson
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ISOINDOLINONE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE
Publication number
20140038936
Publication date
Feb 6, 2014
Alex Aronov
C07 - ORGANIC CHEMISTRY
Information
Patent Application
BENZIMIDAZOLE ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIR...
Publication number
20130157997
Publication date
Jun 20, 2013
Vertex Pharmaceuticals Incorporated.
James A. Henderson
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS
Publication number
20130102629
Publication date
Apr 25, 2013
Vertex Pharmaceuticals Incorporated.
John Maxwell
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS
Publication number
20130090351
Publication date
Apr 11, 2013
Vertex Pharmaceuticals Incorporated.
Sanjoy Kumar Das
C07 - ORGANIC CHEMISTRY