James Elliot BRADNER

Person

Weston, MA, US

People

Patents Grantslast 30 patents

Information Patent Grant
Chromobox protein inhibitors and uses thereof
- Patent number 12,129,248
- Issue date Oct 29, 2024
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Tunable endogenous protein degradation with heterobifunctional comp...
- Patent number 12,023,385
- Issue date Jul 2, 2024
- Dana-Farber Cancer Institute, Inc.
- Dennis Buckley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for selective protein degradation
- Patent number 11,999,802
- Issue date Jun 4, 2024
- Novartis AG
- James E. Bradner
- G01 - MEASURING TESTING
Information Patent Grant
Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the t...
- Patent number 11,944,625
- Issue date Apr 2, 2024
- The Children's Medical Center Corporation
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compounds and methods for treating cancer
- Patent number 11,845,728
- Issue date Dec 19, 2023
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Mechanism of resistance to bet bromodomain inhibitors
- Patent number 11,666,580
- Issue date Jun 6, 2023
- Dana-Farber Cancer Institute, Inc.
- Kornelia Polyak
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 11,583,586
- Issue date Feb 21, 2023
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Degradation of protein kinases by conjugation of protein kinase inh...
- Patent number 11,578,075
- Issue date Feb 14, 2023
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Combination therapy for cancer using bromodomain and extra-terminal...
- Patent number 11,446,309
- Issue date Sep 20, 2022
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Acetamide thienotriazolodiazepines and uses thereof
- Patent number 11,406,645
- Issue date Aug 9, 2022
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Regulating chimeric antigen receptors
- Patent number 11,311,609
- Issue date Apr 26, 2022
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cyano thienotriazolodiazepines and uses thereof
- Patent number 11,306,105
- Issue date Apr 19, 2022
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Tunable endogenous protein degradation
- Patent number 11,293,023
- Issue date Apr 5, 2022
- Dana-Farber Cancer Institute, Inc.
- Dennis Buckley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Degradation of bromodomain-containing protein 9 (BRD9) by conjugati...
- Patent number 11,285,218
- Issue date Mar 29, 2022
- Dana-Farber Cancer Institute, Inc.
- Dennis Buckley
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
EZH2 inhibitors and uses thereof
- Patent number 11,236,082
- Issue date Feb 1, 2022
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 11,059,801
- Issue date Jul 13, 2021
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Targeted protein degradation to attenuate adoptive T-cell therapy a...
- Patent number 11,046,954
- Issue date Jun 29, 2021
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the t...
- Patent number 10,980,808
- Issue date Apr 20, 2021
- The Children's Medical Center Corporation
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compounds and methods for treating cancer
- Patent number 10,934,256
- Issue date Mar 2, 2021
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Degradation of protein kinases by conjugation of protein kinase inh...
- Patent number 10,925,868
- Issue date Feb 23, 2021
- Dana-Farber Cancer Institute, Inc.
- Nathanael S. Gray
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bivalent bromodomain inhibitors and uses thereof
- Patent number 10,913,752
- Issue date Feb 9, 2021
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Degradation of protein kinases by conjugation of protein kinase inh...
- Patent number 10,899,768
- Issue date Jan 26, 2021
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Acetamide thienotriazolodiazepines and uses thereof
- Patent number 10,881,668
- Issue date Jan 5, 2021
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods to induce targeted protein degradation through bifunctional...
- Patent number 10,849,980
- Issue date Dec 1, 2020
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bromodomain inhibitor as adjuvant in cancer immunotherapy
- Patent number 10,813,939
- Issue date Oct 27, 2020
- H. Lee Moffitt Cancer Center & Research Institute, Inc.
- Eduardo M. Sotomayor
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Uses of diazepane derivatives
- Patent number 10,793,571
- Issue date Oct 6, 2020
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Diaminopyrimidine benzenesulfone derivatives and uses thereof
- Patent number 10,730,860
- Issue date Aug 4, 2020
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Degradation of tripartite motif-containing protein 24 (TRIM24) by c...
- Patent number 10,702,504
- Issue date Jul 7, 2020
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Method for preparing largazole analogs and uses thereof
- Patent number 10,676,504
- Issue date Jun 9, 2020
- Colorado State University Research Foundation
- Robert M. Williams
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods for treating leukemia
- Patent number 10,676,484
- Issue date Jun 9, 2020
- Dana-Farber Cancer Institute, Inc.
- James Elliott Bradner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
CHROMOBOX PROTEIN INHIBITORS AND USES THEREOF
- Publication number 20250034126
- Publication date Jan 30, 2025
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION
- Publication number 20240384007
- Publication date Nov 21, 2024
- Novartis AG
- James E. Bradner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE T...
- Publication number 20240342173
- Publication date Oct 17, 2024
- The Children's Medical Center Corporation
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DEGRADATION OF EXTRACELLULAR TARGETS
- Publication number 20240309084
- Publication date Sep 19, 2024
- Novartis AG
- Martin ALLAN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
STABILIZED PEPTIDE-MEDIATED TARGETED PROTEIN DEGRADATION
- Publication number 20240140999
- Publication date May 2, 2024
- Dana-Farber Cancer Institute, Inc.
- Loren D. Walensky
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOUNDS AND METHODS FOR TREATING CANCER
- Publication number 20240092735
- Publication date Mar 21, 2024
- Dana-Farber Cancer Institute, Inc.
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIES
- Publication number 20230279394
- Publication date Sep 7, 2023
- Novartis AG
- Muluken BELEW
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...
- Publication number 20230131952
- Publication date Apr 27, 2023
- Dana-Farber Cancer Institute, Inc.
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TUNABLE ENDOGENOUS PROTEIN DEGRADATION
- Publication number 20220135967
- Publication date May 5, 2022
- Dana-Farber Cancer Institute, Inc.
- Dennis Buckley
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF
- Publication number 20220119416
- Publication date Apr 21, 2022
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE T...
- Publication number 20220008420
- Publication date Jan 13, 2022
- The Children's Medical Center Corporation
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ACETAMIDE THIENOTRIAZOLODIAZEPINES AND USES THEREOF
- Publication number 20210393647
- Publication date Dec 23, 2021
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TARGETED PROTEIN DEGRADATION TO ATTENUATE ADOPTIVE T-CELL THERAPY A...
- Publication number 20210301286
- Publication date Sep 30, 2021
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF
- Publication number 20210221826
- Publication date Jul 22, 2021
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF
- Publication number 20210206779
- Publication date Jul 8, 2021
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOUNDS AND METHODS FOR TREATING CANCER
- Publication number 20210147359
- Publication date May 20, 2021
- Dana-Farber Cancer Institute, Inc.
- James BRADNER
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMBINATION THERAPY FOR CANCER USING BROMODOMAIN AND EXTRA-TERMINAL...
- Publication number 20210100813
- Publication date Apr 8, 2021
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ACETAMIDE THIENOTRIAZOLODIAZEPINES AND USES THEREOF
- Publication number 20210093644
- Publication date Apr 1, 2021
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...
- Publication number 20210061811
- Publication date Mar 4, 2021
- Dana-Farber Cancer Institute, Inc.
- James BRADNER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...
- Publication number 20210015929
- Publication date Jan 21, 2021
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
MECHANISM OF RESISTANCE TO BET BROMODOMAIN INHIBITORS
- Publication number 20200368248
- Publication date Nov 26, 2020
- Dana-Farber Cancer Institute, Inc.
- Kornelia Polyak
- G01 - MEASURING TESTING
Information Patent Application
STABILIZED PEPTIDE-MEDIATED TARGETED PROTEIN DEGRADATION
- Publication number 20200354413
- Publication date Nov 12, 2020
- Dana-Farber Cancer Institute, Inc.
- Loren D. Walensky
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION
- Publication number 20200339704
- Publication date Oct 29, 2020
- Novartis AG
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...
- Publication number 20200317635
- Publication date Oct 8, 2020
- Dana-Farber Cancer Institute, Inc.
- James Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BIFUNCTIONAL MOLECULES FOR HER3 DEGRADATION AND METHODS OF USE
- Publication number 20200216454
- Publication date Jul 9, 2020
- Dana-Farber Cancer Institute, Inc.
- Nathanael S. GRAY
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF
- Publication number 20200199150
- Publication date Jun 25, 2020
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF
- Publication number 20200172553
- Publication date Jun 4, 2020
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS FOR TREATING NEOPLASIA, INFLAMMATORY DISEA...
- Publication number 20200148702
- Publication date May 14, 2020
- Dana-Farber Cancer Institute, Inc.
- James Elliott Bradner
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHODS FOR GENETIC MODIFICATION OF HEMATOPOIETIC CELLS
- Publication number 20200121721
- Publication date Apr 23, 2020
- The Brigham & Women's Hospital, Inc.
- Alexander FEDERATION
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
EZH2 INHIBITORS AND USES THEREOF
- Publication number 20200039968
- Publication date Feb 6, 2020
- Dana-Farber Cancer Institute, Inc.
- James E. Bradner
- C07 - ORGANIC CHEMISTRY

James Elliot BRADNER

Person

Patents Grantslast 30 patents

Chromobox protein inhibitors and uses thereof

Tunable endogenous protein degradation with heterobifunctional comp...

Compositions and methods for selective protein degradation

Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the t...

Compounds and methods for treating cancer

Mechanism of resistance to bet bromodomain inhibitors

Methods to induce targeted protein degradation through bifunctional...

Degradation of protein kinases by conjugation of protein kinase inh...

Combination therapy for cancer using bromodomain and extra-terminal...

Acetamide thienotriazolodiazepines and uses thereof

Regulating chimeric antigen receptors

Cyano thienotriazolodiazepines and uses thereof

Tunable endogenous protein degradation

Degradation of bromodomain-containing protein 9 (BRD9) by conjugati...

EZH2 inhibitors and uses thereof

Methods to induce targeted protein degradation through bifunctional...

Targeted protein degradation to attenuate adoptive T-cell therapy a...

Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the t...

Compounds and methods for treating cancer

Degradation of protein kinases by conjugation of protein kinase inh...

Bivalent bromodomain inhibitors and uses thereof

Degradation of protein kinases by conjugation of protein kinase inh...

Acetamide thienotriazolodiazepines and uses thereof

Methods to induce targeted protein degradation through bifunctional...

Bromodomain inhibitor as adjuvant in cancer immunotherapy

Uses of diazepane derivatives

Diaminopyrimidine benzenesulfone derivatives and uses thereof

Degradation of tripartite motif-containing protein 24 (TRIM24) by c...

Method for preparing largazole analogs and uses thereof

Compositions and methods for treating leukemia

Patents Applicationslast 30 patents

CHROMOBOX PROTEIN INHIBITORS AND USES THEREOF

COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION

CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE T...

DEGRADATION OF EXTRACELLULAR TARGETS

STABILIZED PEPTIDE-MEDIATED TARGETED PROTEIN DEGRADATION

COMPOUNDS AND METHODS FOR TREATING CANCER

COMPOSITIONS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIES

DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...

TUNABLE ENDOGENOUS PROTEIN DEGRADATION

BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF

CALMODULIN INHIBITORS, CHK2 INHIBITORS AND RSK INHIBITORS FOR THE T...

ACETAMIDE THIENOTRIAZOLODIAZEPINES AND USES THEREOF

TARGETED PROTEIN DEGRADATION TO ATTENUATE ADOPTIVE T-CELL THERAPY A...

BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF

CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF

COMPOUNDS AND METHODS FOR TREATING CANCER

COMBINATION THERAPY FOR CANCER USING BROMODOMAIN AND EXTRA-TERMINAL...

ACETAMIDE THIENOTRIAZOLODIAZEPINES AND USES THEREOF

DEGRADATION OF PROTEIN KINASES BY CONJUGATION OF PROTEIN KINASE INH...

METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...

MECHANISM OF RESISTANCE TO BET BROMODOMAIN INHIBITORS

STABILIZED PEPTIDE-MEDIATED TARGETED PROTEIN DEGRADATION

COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION

METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL...

BIFUNCTIONAL MOLECULES FOR HER3 DEGRADATION AND METHODS OF USE

CYANO THIENOTRIAZOLODIAZEPINES AND USES THEREOF

BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF

COMPOSITIONS AND METHODS FOR TREATING NEOPLASIA, INFLAMMATORY DISEA...

METHODS FOR GENETIC MODIFICATION OF HEMATOPOIETIC CELLS

EZH2 INHIBITORS AND USES THEREOF