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John P. Toscano
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Glen Arm, MD, US
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Patents Grants
last 30 patents
Information
Patent Grant
Nitroxyl donors with improved therapeutic index
Patent number
12,186,301
Issue date
Jan 7, 2025
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Hydropersulfide precursors
Patent number
11,926,580
Issue date
Mar 12, 2024
The Johns Hopkins University
John Pasquale Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitroxyl donors with improved therapeutic index
Patent number
11,786,501
Issue date
Oct 17, 2023
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Alkylamine-substituted perthiocarbamates as dual precursors to hydr...
Patent number
11,584,712
Issue date
Feb 21, 2023
The Johns Hopkins University
John Pasquale Toscano
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Pharmaceutical compositions comprising nitroxyl donors
Patent number
11,304,924
Issue date
Apr 19, 2022
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
N-hydroxylsulfonamide derivatives as new physiologically useful nit...
Patent number
11,306,056
Issue date
Apr 19, 2022
Cardioxyl Pharmaceuticals, Inc.
John P. Toscano
Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMA...
Information
Patent Grant
Nitroxyl donors with improved therapeutic index
Patent number
11,273,143
Issue date
Mar 15, 2022
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
O-substituted hydroxamic acids
Patent number
10,913,728
Issue date
Feb 9, 2021
The Johns Hopkins University
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
N-hydroxylsulfonamide derivatives as new physiologically useful nit...
Patent number
10,829,445
Issue date
Nov 10, 2020
Cardioxyl Pharmaceuticals, Inc.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitroxyl donors with improved therapeutic index
Patent number
10,792,273
Issue date
Oct 6, 2020
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
N-hydroxylsulfonamide derivatives as nitroxyl donors
Patent number
10,730,828
Issue date
Aug 4, 2020
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
N-substituted hydroxamic acids with carbon-based leaving groups as...
Patent number
10,583,141
Issue date
Mar 10, 2020
The Johns Hopkins University
John P. Toscano
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Pharmaceutical compositions comprising nitroxyl donors
Patent number
10,548,872
Issue date
Feb 4, 2020
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitroxyl donors with improved therapeutic index
Patent number
10,517,847
Issue date
Dec 31, 2019
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
N-hydroxylsulfonamide derivatives as new physiologically useful nit...
Patent number
10,487,049
Issue date
Nov 26, 2019
Cardioxyl Pharmaceuticals, Inc.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitroxyl progenitor compounds and methods of use
Patent number
10,273,202
Issue date
Apr 30, 2019
The Johns Hopkins University
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pharmaceutical compositions comprising nitroxyl donors
Patent number
10,245,249
Issue date
Apr 2, 2019
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitroxyl donors with improved therapeutic index
Patent number
10,213,408
Issue date
Feb 26, 2019
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
N-hydroxylsulfonamide derivatives as new physiologically useful nit...
Patent number
10,179,765
Issue date
Jan 15, 2019
Cardioxyl Pharmaceuticals, Inc.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitroxyl donors with improved therapeutic index
Patent number
9,968,584
Issue date
May 15, 2018
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
N-hydroxylsulfonamide derivatives as new physiologically useful nit...
Patent number
9,969,684
Issue date
May 15, 2018
Cardioxyl Pharmaceuticals, Inc.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Meldrum's acid, barbituric acid and pyrazolone derivatives substitu...
Patent number
9,862,699
Issue date
Jan 9, 2018
The Johns Hopkins University
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
N-hydroxylsulfonamide derivatives as new physiologically useful nit...
Patent number
9,725,410
Issue date
Aug 8, 2017
The Johns Hopkins University
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pyrazolone derivatives as nitroxyl donors
Patent number
9,682,938
Issue date
Jun 20, 2017
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Controlled HNO release through intramolecular cyclization-elimination
Patent number
9,676,708
Issue date
Jun 13, 2017
The Johns Hopkins University
John P. Toscano
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
N-hydroxylsulfonamide derivatives as new physiologically useful nit...
Patent number
9,617,208
Issue date
Apr 11, 2017
Cardioxyl Pharmaceuticals, Inc.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitroxyl donors with improved therapeutic index
Patent number
9,586,896
Issue date
Mar 7, 2017
Cardioxyl Pharmaceuticals, Inc.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
N-substituted hydroxylamine derivatives with carbon-based leaving g...
Patent number
9,499,511
Issue date
Nov 22, 2016
The Johns Hopkins University
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
N-hydroxylsulfonamide derivatives as new physiologically useful nit...
Patent number
9,487,498
Issue date
Nov 8, 2016
The Johns Hopkins University
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
N-hydroxylamino-barbituric acid derivatives
Patent number
9,464,061
Issue date
Oct 11, 2016
The Johns Hopkins University
John P. Toscano
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
A SOLID-GAS REACTION TO GENERATE NITROXYL (HNO) IN THE GAS PHASE
Publication number
20240269164
Publication date
Aug 15, 2024
The Johns Hopkins University
John Pasquale Toscano
C01 - INORGANIC CHEMISTRY
Information
Patent Application
NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX
Publication number
20240066002
Publication date
Feb 29, 2024
CARDIOXYL PHARMACEUTICALS, INC.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDR...
Publication number
20230242479
Publication date
Aug 3, 2023
The Johns Hopkins University
John Pasquale Toscano
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX
Publication number
20220193026
Publication date
Jun 23, 2022
CARDIOXYL PHARMACEUTICALS, INC.
Vincent Jacob Kalish
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDR...
Publication number
20210238134
Publication date
Aug 5, 2021
The Johns Hopkins University
John Pasquale Toscano
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
HYDROPERSULFIDE PRECURSORS
Publication number
20210179553
Publication date
Jun 17, 2021
John Pasquale TOSCANO
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NIT...
Publication number
20210053915
Publication date
Feb 25, 2021
CARDIOXYL PHARMACEUTICALS, INC.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX
Publication number
20210015784
Publication date
Jan 21, 2021
CARDIOXYL PHARMACEUTICALS, INC.
Vincent Jacob Kalish
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PHARMACEUTICAL COMPOSITIONS COMPRISING NITROXYL DONORS
Publication number
20200163929
Publication date
May 28, 2020
CARDIOXYL PHARMACEUTICALS, INC.
Vincent Jacob Kalish
C07 - ORGANIC CHEMISTRY
Information
Patent Application
NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX
Publication number
20200121633
Publication date
Apr 23, 2020
CARDIOXYL PHARMACEUTICALS, INC.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NIT...
Publication number
20200087253
Publication date
Mar 19, 2020
CARDIOXYL PHARMACEUTICALS, INC.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PHARMACEUTICAL COMPOSITIONS COMPRISING NITROXYL DONORS
Publication number
20190224159
Publication date
Jul 25, 2019
CARDIOXYL PHARMACEUTICALS, INC.
Vincent Jacob Kalish
C07 - ORGANIC CHEMISTRY
Information
Patent Application
O-SUBSTITUTED HYDROXAMIC ACIDS
Publication number
20190161464
Publication date
May 30, 2019
The Johns Hopkins University
John P. Toscano
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NIT...
Publication number
20190144380
Publication date
May 16, 2019
CARDIOXYL PHARMACEUTICALS, INC.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX
Publication number
20190133990
Publication date
May 9, 2019
CARDIOXYL PHARMACEUTICALS, INC.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
N-HYDROXYLSULFONAMIDE DERIVATIVES AS NITROXYL DONORS
Publication number
20180305304
Publication date
Oct 25, 2018
CARDIOXYL PHARMACEUTICALS, INC.
Vincent Jacob Kalish
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NIT...
Publication number
20180244610
Publication date
Aug 30, 2018
CARDIOXYL PHARMACEUTICALS, INC.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX
Publication number
20180235927
Publication date
Aug 23, 2018
CARDIOXYL PHARMACEUTICALS, INC.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
N-SUBSTITUTED HYDROXAMIC ACIDS WITH CARBON-BASED LEAVING GROUPS AS...
Publication number
20180185367
Publication date
Jul 5, 2018
The Johns Hopkins University
John P. Toscano
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
N-ACYLOXYSULFONAMIDE AND N-HYDROXY-N-ACYLSULFONAMIDE DERIVATIVES
Publication number
20180050985
Publication date
Feb 22, 2018
The Johns Hopkins University
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NIT...
Publication number
20170305847
Publication date
Oct 26, 2017
CARDIOXYL PHARMACEUTICALS, INC.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX
Publication number
20170151210
Publication date
Jun 1, 2017
CARDIOXYL PHARMACEUTICALS, INC.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MELDRUM'S ACID, BARBITURIC ACID AND PYRAZOLONE DERIVATIVES SUBSTITU...
Publication number
20170050947
Publication date
Feb 23, 2017
The Johns Hopkins University
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NIT...
Publication number
20170022154
Publication date
Jan 26, 2017
CARDIOXYL PHARMACEUTICALS, INC.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N-SUBSTITUTED HYDROXYLAMINE DERIVATIVES WITH CARBON-BASED LEAVING G...
Publication number
20160115148
Publication date
Apr 28, 2016
The Johns Hopkins University
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N-HYDROXYLAMINO-BARBITURIC ACID DERIVATIVES
Publication number
20160060229
Publication date
Mar 3, 2016
The Johns Hopkins University
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N-ACYLOXYSULFONAMIDE AND N-HYDROXY-N-ACYLSULFONAMIDE DERIVATIVES
Publication number
20160046570
Publication date
Feb 18, 2016
The Johns Hopkins University
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX
Publication number
20160031807
Publication date
Feb 4, 2016
CARDIOXYL PHARMACEUTICALS, INC.
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NIT...
Publication number
20160002156
Publication date
Jan 7, 2016
CARDIOXYL PHARMACEUTICALS, INC.
John P. Toscano
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PHARMACEUTICAL COMPOSITIONS COMPRISING NITROXYL DONORS
Publication number
20150366977
Publication date
Dec 24, 2015
CARDIOXYL PHARMACEUTICALS
Vincent Jacob Kalish
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE