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John Sapienza
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Chula Vista, CA, US
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Patents Grants
last 30 patents
Information
Patent Grant
Cereblon binding compounds, compositions thereof, and methods of tr...
Patent number
12,103,920
Issue date
Oct 1, 2024
Celgene Corporation
Matthew D. Alexander
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted 3-((3-aminophenyl)amino)piperidine-2,6-dione compounds,...
Patent number
11,873,283
Issue date
Jan 16, 2024
Celgene Corporation
Massimo Ammirante
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Cereblon binding compounds, compositions thereof, and methods of tr...
Patent number
11,739,075
Issue date
Aug 29, 2023
Celgene Corporation
Matthew D. Alexander
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Cereblon binding compounds, compositions thereof, and methods of tr...
Patent number
11,634,407
Issue date
Apr 25, 2023
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Cereblon binding compounds, compositions thereof, and methods of tr...
Patent number
11,560,371
Issue date
Jan 24, 2023
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Antiproliferative compounds, and their pharmaceutical compositions...
Patent number
11,365,184
Issue date
Jun 21, 2022
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted 3-((3-aminophenyl)amino)piperidine-2,6-dione compounds,...
Patent number
11,325,889
Issue date
May 10, 2022
Celgene Corporation
Massimo Ammirante
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
Patent number
11,292,796
Issue date
Apr 5, 2022
Signal Pharmaceuticals, LLC
Jan Elsner
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted 3-((3-aminophenyl)amino)piperidine-2,6-dione compounds,...
Patent number
11,149,007
Issue date
Oct 19, 2021
Celgene Corporation
Massimo Ammirante
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
Patent number
10,683,298
Issue date
Jun 16, 2020
Signal Pharmaceuticals, LLC
Jan Elsner
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Antiproliferative compounds, and their pharmaceutical compositions...
Patent number
10,618,883
Issue date
Apr 14, 2020
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Antiproliferative compounds, and their pharmaceutical compositions...
Patent number
10,227,325
Issue date
Mar 12, 2019
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
Patent number
10,167,290
Issue date
Jan 1, 2019
Signal Pharmaceuticals, LLC
Jan Elsner
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Antiproliferative compounds, and their pharmaceutical compositions...
Patent number
9,938,254
Issue date
Apr 10, 2018
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted diaminopyrimidyl compounds, compositions thereof, and m...
Patent number
9,783,505
Issue date
Oct 10, 2017
Signal Pharmaceuticals, LLC
Patrick Papa
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
Patent number
9,771,371
Issue date
Sep 26, 2017
Signal Pharmaceuticals, LLC
Jan Elsner
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted diaminopyrimidyl compounds, compositions thereof, and m...
Patent number
9,556,126
Issue date
Jan 31, 2017
Signal Pharmaceuticals, LLC
Patrick Papa
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Halogen substituted pyrazines as intermediates of mTOR kinase inhib...
Patent number
9,193,692
Issue date
Nov 24, 2015
Signal Pharmaceuticals, LLC
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted diaminopyrimidyl compounds, compositions thereof, and m...
Patent number
9,156,798
Issue date
Oct 13, 2015
Signal Pharmaceuticals, LLC
Sogole Bahmanyar
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods of synthesis and purification of heteroaryl compounds
Patent number
9,079,900
Issue date
Jul 14, 2015
Signal Pharmaceuticals, LLC
Roy L. Harris
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
Patent number
8,907,087
Issue date
Dec 9, 2014
Signal Pharmaceuticals, LLC
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods of synthesis and purification of heteroaryl compounds
Patent number
8,569,494
Issue date
Oct 29, 2013
Signal Pharmaceuticals, LLC
Roy L. Harris
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indicati...
Patent number
8,507,492
Issue date
Aug 13, 2013
Signal Pharmaceuticals, LLC
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indicati...
Patent number
8,492,381
Issue date
Jul 23, 2013
Signal Pharmaceuticals, LLC
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods of treatment using heteroaryl compounds and compositions th...
Patent number
8,383,634
Issue date
Feb 26, 2013
Signal Pharmaceuticals, LLC
Deborah Sue Mortensen
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods of treatment comprising the administration of heteroaryl co...
Patent number
8,372,976
Issue date
Feb 12, 2013
Signal Pharmaceuticals, LLC
Deborah Sue Mortensen
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Aminotriazolopyridines, compositions thereof, and methods of treatm...
Patent number
8,299,056
Issue date
Oct 30, 2012
Signal Pharmaceuticals, LLC
Sogole Bahmanyar
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indicat...
Patent number
8,110,578
Issue date
Feb 7, 2012
Signal Pharmaceuticals, LLC
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Haloaryl substituted aminopurines, compositions thereof, and method...
Patent number
8,101,588
Issue date
Jan 24, 2012
Signal Pharmaceuticals, LLC
Ronald J. Albers
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Heteroaryl compounds, compositions thereof, and methods of treatmen...
Patent number
7,981,893
Issue date
Jul 19, 2011
Signal Pharmaceuticals, LLC
Deborah Sue Mortensen
C07 - ORGANIC CHEMISTRY
Patents Applications
last 30 patents
Information
Patent Application
CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TR...
Publication number
20240374591
Publication date
Nov 14, 2024
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SUBSTITUTED 3-((3-AMINOPHENYL)AMINO)PIPERIDINE-2,6-DIONE COMPOUNDS,...
Publication number
20240368083
Publication date
Nov 7, 2024
Celgene Corporation
Massimo Ammirante
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TR...
Publication number
20240368118
Publication date
Nov 7, 2024
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS
Publication number
20240158370
Publication date
May 16, 2024
Innovo Therapeutics, Inc.
Patrick W. Papa
C07 - ORGANIC CHEMISTRY
Information
Patent Application
WEE1 Degrading Compounds and Uses Thereof
Publication number
20240067632
Publication date
Feb 29, 2024
Bristol-Myers Squibb Company
John Sapienza
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TR...
Publication number
20230348431
Publication date
Nov 2, 2023
Ceigene Corporation
Matthew D. Alexander
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TR...
Publication number
20230242509
Publication date
Aug 3, 2023
Ceigene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20230119470
Publication date
Apr 20, 2023
Signal Pharmaceuticals, LLC.
Jan ELSNER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED 3-((3-AMINOPHENYL)AMINO)PIPERIDINE-2,6-DIONE COMPOUNDS,...
Publication number
20230002321
Publication date
Jan 5, 2023
Celgene Corporation
Massimo Ammirante
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TR...
Publication number
20220002273
Publication date
Jan 6, 2022
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TR...
Publication number
20210403454
Publication date
Dec 30, 2021
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CEREBLON BINDING COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TR...
Publication number
20210403453
Publication date
Dec 30, 2021
Celgene Corporation
Matthew D. Alexander
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ANTIPROLIFERATIVE COMPOUNDS, AND THEIR PHARMACEUTICAL COMPOSITIONS...
Publication number
20210040063
Publication date
Feb 11, 2021
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20200262840
Publication date
Aug 20, 2020
Signal Pharmaceuticals, LLC.
Jan ELSNER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED 3-((3-AMINOPHENYL)AMINO)PIPERIDINE-2,6-DIONE COMPOUNDS,...
Publication number
20200199074
Publication date
Jun 25, 2020
Celgene Corporation
Massimo Ammirante
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED 3-((3-AMINOPHENYL)AMINO)PIPERIDINE-2,6-DIONE COMPOUNDS,...
Publication number
20200199073
Publication date
Jun 25, 2020
Celgene Corporation
Massimo Ammirante
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ANTIPROLIFERATIVE COMPOUNDS, AND THEIR PHARMACEUTICAL COMPOSITIONS...
Publication number
20190152942
Publication date
May 23, 2019
Celgene Corporation
Matthew D. Alexander
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20190077806
Publication date
Mar 14, 2019
Signal Pharmaceuticals, LLC.
Jan ELSNER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ANTIPROLIFERATIVE COMPOUNDS, AND THEIR PHARMACEUTICAL COMPOSITIONS...
Publication number
20180186767
Publication date
Jul 5, 2018
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20170342080
Publication date
Nov 30, 2017
Signal Pharmaceuticals, LLC.
Jan ELSNER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ANTIPROLIFERATIVE COMPOUNDS, AND THEIR PHARMACEUTICAL COMPOSITIONS...
Publication number
20170197933
Publication date
Jul 13, 2017
Celgene Corporation
Matthew D. Alexander
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND M...
Publication number
20160354374
Publication date
Dec 8, 2016
Signal Pharmaceuticals, LLC.
Patrick Papa
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20160024101
Publication date
Jan 28, 2016
Signal Pharmaceuticals, LLC.
Jan ELSNER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND M...
Publication number
20150246890
Publication date
Sep 3, 2015
Signal Pharmaceuticals, LLC.
Sogole BAHMANYAR
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND M...
Publication number
20150175557
Publication date
Jun 25, 2015
Signal Pharmaceuticals, LLC.
Patrick Papa
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20150051397
Publication date
Feb 19, 2015
Signal Pharmaceuticals, LLC.
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS
Publication number
20140155593
Publication date
Jun 5, 2014
Signal Pharmaceuticals, LLC.
Roy L. Harris
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICAT...
Publication number
20130289271
Publication date
Oct 31, 2013
Signal Pharmaceuticals, LLC.
Sophie Perrin-Ninkovic
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS
Publication number
20130245254
Publication date
Sep 19, 2013
Signal Pharmaceuticals, LLC.
Roy L. Harris
C07 - ORGANIC CHEMISTRY
Information
Patent Application
AMINOTRIAZOLOPYRIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATM...
Publication number
20130005707
Publication date
Jan 3, 2013
Sogole Bahmanyar
C07 - ORGANIC CHEMISTRY