Joly Sukumaran

Person

Singapore, SG

People

Patents Grantslast 30 patents

Information Patent Grant
Lov-D acyltransferase mediated acylation
- Patent number 12,060,592
- Issue date Aug 13, 2024
- Codexis, Inc.
- Steven J. Collier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Variant LovD polypeptides and their uses
- Patent number 11,926,857
- Issue date Mar 12, 2024
- Codexis, Inc.
- Lynne Gilson
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 11,618,911
- Issue date Apr 4, 2023
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 11,377,673
- Issue date Jul 5, 2022
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Variant LovD polypeptides and their uses
- Patent number 11,046,982
- Issue date Jun 29, 2021
- Codexis, Inc.
- Lynne Gilson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 10,947,572
- Issue date Mar 16, 2021
- Codexis, Inc.
- Haibin Chen
- Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMA...
Information Patent Grant
Lov-D acyltransferase mediated acylation
- Patent number 10,858,680
- Issue date Dec 8, 2020
- Codexis, Inc.
- Steven J. Collier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 10,787,689
- Issue date Sep 29, 2020
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Variant LovD polypeptides and their uses
- Patent number 10,590,445
- Issue date Mar 17, 2020
- Codexis, Inc.
- Lynne Gilson
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 10,494,656
- Issue date Dec 3, 2019
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Lov-D acyltransferase mediated acylation
- Patent number 10,428,360
- Issue date Oct 1, 2019
- Codexis, Inc.
- Steven J. Collier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nucleic acids encoding engineered imine reductases
- Patent number 10,308,966
- Issue date Jun 4, 2019
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 10,160,983
- Issue date Dec 25, 2018
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 10,066,250
- Issue date Sep 4, 2018
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Biocatalytic process for preparing eslicarbazepine and analogs thereof
- Patent number 9,963,683
- Issue date May 8, 2018
- Codexis, Inc.
- Anupam Gohel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 9,932,613
- Issue date Apr 3, 2018
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Variant LovD polypeptides and their uses
- Patent number 9,932,616
- Issue date Apr 3, 2018
- Codexis, Inc.
- Lynne Gilson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Lov-D acyltransferase mediated acylation
- Patent number 9,909,156
- Issue date Mar 6, 2018
- Codexis, Inc.
- Steven J. Collier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 9,828,614
- Issue date Nov 28, 2017
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 9,803,224
- Issue date Oct 31, 2017
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Polynucleotides encoding engineered imine reductases
- Patent number 9,695,451
- Issue date Jul 4, 2017
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered biocatalysts useful for carbapenem synthesis
- Patent number 9,663,771
- Issue date May 30, 2017
- Codexis, Inc.
- Joly Sukumaran
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Biocatalytic process for preparing eslicarbazepine and analogs thereof
- Patent number 9,605,290
- Issue date Mar 28, 2017
- Codexis, Inc.
- Anupam Gohel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Variant LovD polypeptides and their uses
- Patent number 9,546,388
- Issue date Jan 17, 2017
- Codexis, Inc.
- Lynne Gilson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered biocatalysts useful for carbapenem synthesis
- Patent number 9,540,622
- Issue date Jan 10, 2017
- Codexis, Inc.
- Joly Sukumaran
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 9,487,760
- Issue date Nov 8, 2016
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Lov-D acyltransferase mediated acylation
- Patent number 9,399,785
- Issue date Jul 26, 2016
- Codexis, Inc.
- Steven J. Collier
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Biocatalytic process for preparing eslicarbazepine and analogs thereof
- Patent number 9,365,878
- Issue date Jun 14, 2016
- Codexis, Inc.
- Anupam Gohel
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Engineered imine reductases and methods for the reductive amination...
- Patent number 9,296,993
- Issue date Mar 29, 2016
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered imine reductases and methods for the reductive animation...
- Patent number 9,193,957
- Issue date Nov 24, 2015
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
LOV-D ACYLTRANSFERASE MEDIATED ACYLATION
- Publication number 20240368649
- Publication date Nov 7, 2024
- Codexis Inc.
- Steven J. Collier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VARIANT LOVD POLYPEPTIDES AND THEIR USES
- Publication number 20240218407
- Publication date Jul 4, 2024
- Codexis, Inc.
- Lynne Gilson
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20230295673
- Publication date Sep 21, 2023
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20220315961
- Publication date Oct 6, 2022
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VARIANT LOVD POLYPEPTIDES AND THEIR USES
- Publication number 20210277432
- Publication date Sep 9, 2021
- Codexis, Inc.
- Lynne Gilson
- C07 - ORGANIC CHEMISTRY
Information Patent Application
LOV-D ACYLTRANSFERASE MEDIATED ACYLATION
- Publication number 20210071216
- Publication date Mar 11, 2021
- Codexis Inc.
- Steven J. Collier
- Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMA...
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20210054422
- Publication date Feb 25, 2021
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20200385768
- Publication date Dec 10, 2020
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VARIANT LOVD POLYPEPTIDES AND THEIR USES
- Publication number 20200157588
- Publication date May 21, 2020
- Codexis, Inc.
- Lynne Gilson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20200032303
- Publication date Jan 30, 2020
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LOV-D ACYLTRANSFERASE MEDIATED ACYLATION
- Publication number 20190367956
- Publication date Dec 5, 2019
- Codexis Inc.
- Steven J. Collier
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20190249209
- Publication date Aug 15, 2019
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20190078124
- Publication date Mar 14, 2019
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20180346945
- Publication date Dec 6, 2018
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20180187221
- Publication date Jul 5, 2018
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VARIANT LOVD POLYPEPTIDES AND THEIR USES
- Publication number 20180187225
- Publication date Jul 5, 2018
- Codexis, Inc.
- Lynne Gilson
- C07 - ORGANIC CHEMISTRY
Information Patent Application
LOV-D ACYLTRANSFERASE MEDIATED ACYLATION
- Publication number 20180179565
- Publication date Jun 28, 2018
- Codexis Inc.
- Steven J. Collier
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20180066292
- Publication date Mar 8, 2018
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20170268028
- Publication date Sep 21, 2017
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF
- Publication number 20170159028
- Publication date Jun 8, 2017
- Codexis, Inc.
- Anupam Gohel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VARIANT LOVD POLYPEPTIDES AND THEIR USES
- Publication number 20170081685
- Publication date Mar 23, 2017
- Codexis, Inc.
- Lynne Gilson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED BIOCATALYSTS USEFUL FOR CARBAPENEM SYNTHESIS
- Publication number 20170073654
- Publication date Mar 16, 2017
- Codexis, Inc.
- Joly Sukumaran
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20170022527
- Publication date Jan 26, 2017
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LOV-D ACYLTRANSFERASE MEDIATED ACYLATION
- Publication number 20160304921
- Publication date Oct 20, 2016
- Codexis Inc.
- Steven J. Collier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF
- Publication number 20160244792
- Publication date Aug 25, 2016
- Codexis, Inc.
- Anupam Gohel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20160168545
- Publication date Jun 16, 2016
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
- Publication number 20160040140
- Publication date Feb 11, 2016
- Codexis, Inc.
- Haibin Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED BIOCATALYSTS USEFUL FOR CARBAPENEM SYNTHESIS
- Publication number 20150353976
- Publication date Dec 10, 2015
- Codexis, Inc.
- Joly Sukumaran
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF
- Publication number 20150329835
- Publication date Nov 19, 2015
- Codexis, Inc.
- Anupam Gohel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LOV-D ACYLTRANSFERASE MEDIATED ACYLATION
- Publication number 20150259718
- Publication date Sep 17, 2015
- Codexis Inc.
- Steven J. Collier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Joly Sukumaran

Person

Patents Grantslast 30 patents

Lov-D acyltransferase mediated acylation

Variant LovD polypeptides and their uses

Engineered imine reductases and methods for the reductive amination...

Engineered imine reductases and methods for the reductive amination...

Variant LovD polypeptides and their uses

Engineered imine reductases and methods for the reductive amination...

Lov-D acyltransferase mediated acylation

Engineered imine reductases and methods for the reductive amination...

Variant LovD polypeptides and their uses

Engineered imine reductases and methods for the reductive amination...

Lov-D acyltransferase mediated acylation

Nucleic acids encoding engineered imine reductases

Engineered imine reductases and methods for the reductive amination...

Engineered imine reductases and methods for the reductive amination...

Biocatalytic process for preparing eslicarbazepine and analogs thereof

Engineered imine reductases and methods for the reductive amination...

Variant LovD polypeptides and their uses

Lov-D acyltransferase mediated acylation

Engineered imine reductases and methods for the reductive amination...

Engineered imine reductases and methods for the reductive amination...

Polynucleotides encoding engineered imine reductases

Engineered biocatalysts useful for carbapenem synthesis

Biocatalytic process for preparing eslicarbazepine and analogs thereof

Variant LovD polypeptides and their uses

Engineered biocatalysts useful for carbapenem synthesis

Engineered imine reductases and methods for the reductive amination...

Lov-D acyltransferase mediated acylation

Biocatalytic process for preparing eslicarbazepine and analogs thereof

Engineered imine reductases and methods for the reductive amination...

Engineered imine reductases and methods for the reductive animation...

Patents Applicationslast 30 patents

LOV-D ACYLTRANSFERASE MEDIATED ACYLATION

VARIANT LOVD POLYPEPTIDES AND THEIR USES

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

VARIANT LOVD POLYPEPTIDES AND THEIR USES

LOV-D ACYLTRANSFERASE MEDIATED ACYLATION

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

VARIANT LOVD POLYPEPTIDES AND THEIR USES

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

LOV-D ACYLTRANSFERASE MEDIATED ACYLATION

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

VARIANT LOVD POLYPEPTIDES AND THEIR USES

LOV-D ACYLTRANSFERASE MEDIATED ACYLATION

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF

VARIANT LOVD POLYPEPTIDES AND THEIR USES

ENGINEERED BIOCATALYSTS USEFUL FOR CARBAPENEM SYNTHESIS

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

LOV-D ACYLTRANSFERASE MEDIATED ACYLATION

BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...

ENGINEERED BIOCATALYSTS USEFUL FOR CARBAPENEM SYNTHESIS

BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF

LOV-D ACYLTRANSFERASE MEDIATED ACYLATION