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Waban, MA, US
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Patents Grants
last 30 patents
Information
Patent Grant
Inhibitors of cellular necrosis and related methods
Patent number
10,508,102
Issue date
Dec 17, 2019
President and Fellows of Harvard College
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Inhibitors of cellular necrosis and related methods
Patent number
9,944,628
Issue date
Apr 17, 2018
President and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted indoles and pyrroles as RIP kinase inhibitors
Patent number
9,725,452
Issue date
Aug 8, 2017
Presidents and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Necroptosis inhibitors and methods of use therefor
Patent number
9,643,977
Issue date
May 9, 2017
President and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Small molecule inhibitors of necroptosis
Patent number
9,586,880
Issue date
Mar 7, 2017
President and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibitors of cellular necrosis and related methods
Patent number
9,499,521
Issue date
Nov 22, 2016
President and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Heterocyclic inhibitors of necroptosis
Patent number
9,108,955
Issue date
Aug 18, 2015
President and Fellows of Harvard College
Gregory D. Cuny
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibitors of cellular necrosis
Patent number
8,741,942
Issue date
Jun 3, 2014
President and Fellows of Harvard College
Gregory D. Cuny
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Heterocyclic inhibitors of necroptosis
Patent number
8,658,689
Issue date
Feb 25, 2014
President and Fellows of Harvard College
Gregory D. Cuny
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Tricyclic necrostatin compounds
Patent number
8,324,262
Issue date
Dec 4, 2012
The Brigham & Women's Hospital, Inc.
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Relatedness of human interleukin-1β convertase gene to a C. elegans...
Patent number
8,314,067
Issue date
Nov 20, 2012
Massachusetts Institute of Technology
H. Robert Horvitz
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Heterocyclic inhibitors of necroptosis
Patent number
8,278,344
Issue date
Oct 2, 2012
The Brigham & Women's Hospital, Inc.
Gregory D. Cuny
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibitors of cellular necrosis
Patent number
8,143,300
Issue date
Mar 27, 2012
President and Fellows of Harvard College
Gregory D. Cuny
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibitors of cellular necrosis
Patent number
7,491,743
Issue date
Feb 17, 2009
President and Fellows of Harvard College
Gregory D. Cuny
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Small molecules used to increase cell death
Patent number
7,390,836
Issue date
Jun 24, 2008
President and Fellows of Harvard College
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Small molecule inhibitors of necrosis
Patent number
7,253,201
Issue date
Aug 7, 2007
President and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Small molecules used to increase cell death
Patent number
7,144,905
Issue date
Dec 5, 2006
President and Fellows of Harvard College
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Cloning sequencing and characterization of two cell death genes and...
Patent number
7,138,510
Issue date
Nov 21, 2006
Massachusetts Institute of Technology
H. Robert Horvitz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Cloning sequencing and characterization of two cell death genes and...
Patent number
7,071,302
Issue date
Jul 4, 2006
Massachusetts Institute of Technology
H. Robert Horvitz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Altered human interleukin-1β convertase (ICE), NEDD-2, and C. elega...
Patent number
6,939,850
Issue date
Sep 6, 2005
Massachusetts Institute of Technology
H. Robert Horvitz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Small molecule inhibitors of necrosis
Patent number
6,756,394
Issue date
Jun 29, 2004
President and Fellow of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Small molecules used to increase cell death
Patent number
6,706,766
Issue date
Mar 16, 2004
President and Fellows of Harvard College
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Programmed cell death and caspase-12
Patent number
6,642,368
Issue date
Nov 4, 2003
The General Hospital Corporation
Junying Yuan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for treating cell death diseases and inflammation
Patent number
6,552,071
Issue date
Apr 22, 2003
President and Fellows of Harvard College
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Method for modulating apoptosis
Patent number
6,416,753
Issue date
Jul 9, 2002
The General Hospital Corporation
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Programmed cell death and ICH-3
Patent number
6,214,572
Issue date
Apr 10, 2001
The General Hospital Corporation
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Assays and kits for inhibition of polyglutamine-induced cell death
Patent number
6,177,259
Issue date
Jan 23, 2001
President and Fellows of Harvard College
Junying Yuan
G01 - MEASURING TESTING
Information
Patent Grant
Programmed cell death genes and proteins
Patent number
6,087,160
Issue date
Jul 11, 2000
The General Hospital Corporation
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Programmed cell death genes and proteins
Patent number
6,083,735
Issue date
Jul 4, 2000
The General Hospital Corporation
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Relatedness of human interleukin-1.beta. convertase gene to a C. el...
Patent number
5,962,301
Issue date
Oct 5, 1999
Massachusetts Institute of Technology
H. Robert Horvitz
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
COMPOUNDS AND METHODS FOR BLOCKING APOPTOSIS AND INDUCING AUTOPHAGY
Publication number
20230219898
Publication date
Jul 13, 2023
President and Fellows of Harvard College
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS AND COMPOSITIONS FOR INHIBITING NECROPTOSIS IN NEUROVASCULA...
Publication number
20210147842
Publication date
May 20, 2021
President and Fellows of Harvard College
Junying YUAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SMALL MOLECULE INHIBITORS OF NECROPTOSIS
Publication number
20190135718
Publication date
May 9, 2019
President and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
INHIBITORS OF CELLULAR NECROSIS AND RELATED METHODS
Publication number
20190023690
Publication date
Jan 24, 2019
President and Fellows of Harvard College
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SMALL MOLECULE INHIBITORS OF NECROPTOSIS
Publication number
20170305824
Publication date
Oct 26, 2017
President and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF IN TREATING AUTOPHAGY...
Publication number
20170050929
Publication date
Feb 23, 2017
President and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
INHIBITORS OF CELLULAR NECROSIS AND RELATED METHODS
Publication number
20160304498
Publication date
Oct 20, 2016
President and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Methods for Modulation of Autophagy Through the Modulation of Autop...
Publication number
20160194631
Publication date
Jul 7, 2016
Harvard Medical School
JUNYING YUAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
INHIBITORS OF CELLULAR NECROSIS AND RELATED METHODS
Publication number
20160168128
Publication date
Jun 16, 2016
President and Fellows of Harvard College
Junying YUAN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
HETEROCYCLIC INHIBITORS OF NECROPTOSIS
Publication number
20160102053
Publication date
Apr 14, 2016
President and Fellows of Harvard College
Gregory D. CUNY
C07 - ORGANIC CHEMISTRY
Information
Patent Application
HYBRID NECROPTOSIS INHIBITORS
Publication number
20160024098
Publication date
Jan 28, 2016
President and Fellows of Harvard College
Junying YUAN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
HYBRID NECROPTOSIS INHIBITORS
Publication number
20140323489
Publication date
Oct 30, 2014
President and Fellows of Harvard College
Junying YUAN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
HETEROCYCLIC INHIBITORS OF NECROPTOSIS
Publication number
20140128437
Publication date
May 8, 2014
President and Fellows of Harvard College
Gregory D. Cuny
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Necroptosis Inhibitors and Methods of Use Therefor
Publication number
20140066466
Publication date
Mar 6, 2014
President and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
COMPOUNDS, SCREENS, AND METHODS OF TREATMENT
Publication number
20140024662
Publication date
Jan 23, 2014
Shanghai Institute of Organic Chemistry
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SMALL MOLECULE INHIBITORS OF NECROPTOSIS
Publication number
20140024657
Publication date
Jan 23, 2014
President and Fellows of Harvard College
Junying YUAN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Methods for Modulation of Autophagy Through the Modulation of Autop...
Publication number
20140004108
Publication date
Jan 2, 2014
Harvard Medical School
JUNYING YUAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TRICYCLIC NECROSTATIN COMPOUNDS
Publication number
20130158024
Publication date
Jun 20, 2013
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Methods for Modulation of Autophagy Through the Modulation of Autop...
Publication number
20120315244
Publication date
Dec 13, 2012
PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Junying Yuan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HETEROCYCLIC INHIBITORS OF NECROPTOSIS
Publication number
20120309795
Publication date
Dec 6, 2012
Gregory D. Cuny
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Methods for Modulation of Autophagy Through the Modulation of Autop...
Publication number
20120301463
Publication date
Nov 29, 2012
President and Fellows of Harvard College
Junying Yuan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Potent Small Molecule Inhibitors of Autophagy, and Methods of Use T...
Publication number
20120258975
Publication date
Oct 11, 2012
Shanghai Institute of Organic Chemistry
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
INHIBITORS OF CELLULAR NECROSIS
Publication number
20120149702
Publication date
Jun 14, 2012
The Brigham & Women's Hospital, Inc.
Gregory D. Cuny
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphospha...
Publication number
20120136033
Publication date
May 31, 2012
President and Fellows of Harvard College
Alexei Degterev
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SMALL MOLECULE INHIBITORS OF NECROPTOSIS
Publication number
20120122889
Publication date
May 17, 2012
President and Fellows of Harvard College
Junying Yuan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Methods for Identifying Autophagy Inducing Compounds
Publication number
20120077705
Publication date
Mar 29, 2012
President and Fellows of Harvard College
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Inhibitors of cellular necrosis
Publication number
20110144169
Publication date
Jun 16, 2011
Gregory D. Cuny
C07 - ORGANIC CHEMISTRY
Information
Patent Application
HETEROCYCLIC INHIBITORS OF NECROPTOSIS
Publication number
20100317701
Publication date
Dec 16, 2010
Gregory D. Cuny
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Autophagy Inducing Compounds and Uses Thereof in Treating Autophagy...
Publication number
20100267704
Publication date
Oct 21, 2010
President an Fellows of Harvard Colege
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Compounds, Screens, and Methods of Treatment
Publication number
20100190836
Publication date
Jul 29, 2010
Junying Yuan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE