KARL DANE WITTRUP

Person

CHESTNUT HILL, MA, US

People

Patents Grantslast 30 patents

Information Patent Grant
Combination immunotherapy for treatment of melanoma, colon or non-s...
- Patent number 12,295,986
- Issue date May 13, 2025
- Massachusetts Institute of Technology
- Chensu Wang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Polyclonal mixtures of antibodies, and methods of making and using...
- Patent number 12,258,679
- Issue date Mar 25, 2025
- Adimab, LLC
- Laura M. Walker
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Collagen-localized immunomodulatory molecules and methods thereof
- Patent number 12,227,559
- Issue date Feb 18, 2025
- Massachusetts Institute of Technology
- Karl Dane Wittrup
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bispecific antibodies specific for treating hematological malignancies
- Patent number 11,970,542
- Issue date Apr 30, 2024
- FRED HUTCHINSON CANCER CENTER
- Damian J. Green
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Multi-specific antibodies with affinity for human A33 antigen and D...
- Patent number 11,858,993
- Issue date Jan 2, 2024
- Memorial Sloan Kettering Cancer Center
- Sarah Cheal
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Synthetic oncolytic LNP-replicon RNA and uses for cancer immunotherapy
- Patent number 11,717,548
- Issue date Aug 8, 2023
- Massachusetts Institute of Technology
- Darrell J. Irvine
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Immunomodulatory fusion protein-metal hydroxide complexes and metho...
- Patent number 11,642,409
- Issue date May 9, 2023
- Massachusetts Insttute of Technology
- Darrell J. Irvine
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Multiple specificity binders of CXC chemokines
- Patent number 11,485,781
- Issue date Nov 1, 2022
- Massachusetts Institute of Technology
- Alessandro Angelini
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Monoclonal antibodies that bind human CD161
- Patent number 11,459,389
- Issue date Oct 4, 2022
- Massachusetts Institute of Technology
- Karl Dane Wittrup
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods to specifically profile protease activity at lymph nodes
- Patent number 11,448,643
- Issue date Sep 20, 2022
- Massachusetts Institute of Technology
- Sangeeta N. Bhatia
- B82 - NANO-TECHNOLOGY
Information Patent Grant
Polyclonal mixtures of antibodies, and methods of making and using...
- Patent number 11,390,964
- Issue date Jul 19, 2022
- Adimab, LLC
- Laura M. Walker
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Combination immunotherapy dosing regimen for immune checkpoint bloc...
- Patent number 11,235,032
- Issue date Feb 1, 2022
- Massachusetts Institute of Technology
- Chensu Wang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Synergistic tumor treatment with an extended pharmacokinetic IL-2 a...
- Patent number 11,096,989
- Issue date Aug 24, 2021
- The Board of Trustees of the Leland Stanford Junior University
- Karl Dane Wittrup
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Multi-specific antibodies with affinity for human A33 antigen and D...
- Patent number 10,988,534
- Issue date Apr 27, 2021
- Memorial Sloan Kettering Cancer Center
- Sarah Cheal
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods of treating cancer cells expressing tumor-associated integrins
- Patent number 10,888,603
- Issue date Jan 12, 2021
- The Board of Trustees of the Leland Stanford Junior University
- Karl Dane Wittrup
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Polyclonal mixtures of antibodies, and methods of making and using...
- Patent number 10,684,289
- Issue date Jun 16, 2020
- Adimab, LLC
- Laura M. Walker
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Combination tumor treatment with an integrin-binding-Fc fusion prot...
- Patent number 10,603,358
- Issue date Mar 31, 2020
- NODUS THERAPEUTICS
- Jennifer R. Cochran
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Method of treating cancer with a multiple integrin binding Fc fusio...
- Patent number 10,350,266
- Issue date Jul 16, 2019
- NODUS THERAPEUTICS, INC.
- Jennifer R. Cochran
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Synergistic tumor treatment with antibodies targeting PD-1, PD-L1 o...
- Patent number 10,166,273
- Issue date Jan 1, 2019
- The Board of Trustees of the Leland Stanford Junior University
- Karl Dane Wittrup
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Synergistic tumor treatment with extended-PK IL-2 and therapeutic a...
- Patent number 9,844,582
- Issue date Dec 19, 2017
- Massachusetts Institute of Technology
- Karl Dane Wittrup
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody-based constructs directed against tyrosine kinase receptors
- Patent number 9,464,136
- Issue date Oct 11, 2016
- Massachusetts Institute of Technology
- Karl Dane Wittrup
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Engineered proteins with high affinity for DOTA chelates
- Patent number 8,648,176
- Issue date Feb 11, 2014
- Massachusetts Institute of Technology
- Kelly Davis Orcutt
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Cell display libraries
- Patent number 8,450,247
- Issue date May 28, 2013
- Massachusetts Institute of Technology
- Beau R. Peelle
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Mutant interleukin-2 (IL-2) polypeptides
- Patent number 8,349,311
- Issue date Jan 8, 2013
- Massachusetts Institute of Technology
- Karl Dane Wittrup
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
LUNG-CANCER SPECIFIC T CELL DYSFUNCTION
- Publication number 20240156911
- Publication date May 16, 2024
- Massachusetts Institute of Technology
- Karl Dane Wittrup
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYNTHETIC ONCOLYTIC LNP-REPLICON RNA AND USES FOR CANCER IMMUNOTHERAPY
- Publication number 20240024394
- Publication date Jan 25, 2024
- Massachusetts Institute of Technology
- Darrell J. Irvine
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
IMMUNOMODULATORY FUSION PROTEIN-METAL HYDROXIDE COMPLEXES AND METHO...
- Publication number 20230302128
- Publication date Sep 28, 2023
- Massachusetts Institute of Technology
- Darrell J. IRVINE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ENHANCED-AFFINITY ANTI-ECM NANOBODY-CYTOKINE FUSIONS AND THEIR APPL...
- Publication number 20230295284
- Publication date Sep 21, 2023
- Massachusetts Institute of Technology
- Richard O. Hynes
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COLLAGEN-LOCALIZED IMMUNOMODULATORY MOLECULES AND METHODS THEREOF
- Publication number 20230174623
- Publication date Jun 8, 2023
- Massachusetts Institute of Technology
- Karl Dane WITTRUP
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
POLYCLONAL MIXTURES OF ANTIBODIES, AND METHODS OF MAKING AND USING...
- Publication number 20230071129
- Publication date Mar 9, 2023
- ADIMAB, LLC
- Laura M. Walker
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
METHODS TO SPECIFICALLY PROFILE PROTEASE ACTIVITY AT LYMPH NODES
- Publication number 20230040528
- Publication date Feb 9, 2023
- Massachusetts Institute of Technology
- Sangeeta N. Bhatia
- B82 - NANO-TECHNOLOGY
Information Patent Application
FUSION POLYPEPTIDES
- Publication number 20220372495
- Publication date Nov 24, 2022
- Ankyra Therapeutics, Inc.
- Michael Schmidt
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYNERGISTIC TUMOR TREATMENT WITH IL-2 AND INTEGRIN-BINDING-FC FUSIO...
- Publication number 20220193197
- Publication date Jun 23, 2022
- The Board of Trustees of the Leland Stanford Junior University
- Karl Dane WITTRUP
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMBINATION IMMUNOTHERAPY DOSING REGIMEN FOR IMMUNE CHECKPOINT BLOC...
- Publication number 20220096601
- Publication date Mar 31, 2022
- Massachusetts Institute of Technology
- Chensu WANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS...
- Publication number 20210340524
- Publication date Nov 4, 2021
- Massachusetts Institute of Technology
- Darrell J. IRVINE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF
- Publication number 20210338833
- Publication date Nov 4, 2021
- Massachusetts Institute of Technology
- Darrell J. IRVINE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTI-SPECIFIC ANTIBODIES WITH AFFINITY FOR HUMAN A33 ANTIGEN AND D...
- Publication number 20210301014
- Publication date Sep 30, 2021
- Memorial Sloan-Kettering Cancer Center
- Sarah CHEAL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTIPLE SPECIFICITY BINDERS OF CXC CHEMOKINES AND USES THEREOF
- Publication number 20210246199
- Publication date Aug 12, 2021
- Massachusetts Institute of Technology
- Alessandro ANGELINI
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BISPECIFIC ANTIBODY COMPOSITIONS AND RELATED METHODS FOR IMPROVED P...
- Publication number 20210171651
- Publication date Jun 10, 2021
- Fred Hutchinson Cancer Research Center
- Damian J. Green
- C07 - ORGANIC CHEMISTRY
Information Patent Application
MONOCLONAL ANTIBODIES THAT BIND HUMAN CD161 AND USES THEREOF
- Publication number 20210122826
- Publication date Apr 29, 2021
- Massachusetts Institute of Technology
- Karl Dane WITTRUP
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMBINATION TUMOR TREATMENT WITH AN INTEGRIN-BINDING-FC FUSION PROT...
- Publication number 20210077576
- Publication date Mar 18, 2021
- Nodus Therapeutics
- Jennifer R. COCHRAN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
IMMUNOMODULATORY FUSION PROTEIN-METAL HYDROXIDE COMPLEXES AND METHO...
- Publication number 20200405850
- Publication date Dec 31, 2020
- Massachusetts Institute of Technology
- Darrell J. IRVINE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYNTHETIC ONCOLYTIC LNP-REPLICON RNA AND USES FOR CANCER IMMUNOTHERAPY
- Publication number 20200281994
- Publication date Sep 10, 2020
- Massachusetts Institute of Technology
- Darrell J. Irvine
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
POLYCLONAL MIXTURES OF ANTIBODIES, AND METHODS OF MAKING AND USING...
- Publication number 20200278354
- Publication date Sep 3, 2020
- ADIMAB, LLC
- Laura M. Walker
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMBINATION IMMUNOTHERAPY DOSING REGIMEN FOR IMMUNE CHECKPOINT BLOC...
- Publication number 20200230208
- Publication date Jul 23, 2020
- Massachusetts Institute of Technology
- Chensu WANG
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTI-SPECIFIC ANTIBODIES WITH AFFINITY FOR HUMAN A33 ANTIGEN AND D...
- Publication number 20200140543
- Publication date May 7, 2020
- Memorial Sloan-Kettering Cancer Center
- Sarah CHEAL
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COLLAGEN-LOCALIZED IMMUNOMODULATORY MOLECULES AND METHODS THEREOF
- Publication number 20200102370
- Publication date Apr 2, 2020
- Massachusetts Institute of Technology
- Karl Dane WITTRUP
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYNERGISTIC TUMOR TREATMENT WITH IL-2 AND INTEGRIN-BINDING-FC FUSIO...
- Publication number 20190343925
- Publication date Nov 14, 2019
- The Board of Trustees of the Leland Stanford Junior University
- Karl Dane WITTRUP
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHODS TO SPECIFICALLY PROFILE PROTEASE ACTIVITY AT LYMPH NODES
- Publication number 20190128873
- Publication date May 2, 2019
- Massachusetts Institute of Technology
- Sangeeta N. Bhatia
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SYNERGISTIC TUMOR TREATMENT WITH IL-2, AN INTEGRIN-BINDING-FC FUSIO...
- Publication number 20190054145
- Publication date Feb 21, 2019
- Massachusetts Institute of Technology
- Karl Dane WITTRUP
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMBINATION TUMOR TREATMENT WITH AN INTEGRIN-BINDING-FC FUSION PROT...
- Publication number 20180369329
- Publication date Dec 27, 2018
- Nodus Therapeutics
- Jennifer R. COCHRAN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PROTEIN-CHAPERONED T-CELL VACCINES
- Publication number 20170252417
- Publication date Sep 7, 2017
- Massachusetts Institute of Technology
- Darrell Irvine
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYNERGISTIC TUMOR TREATMENT WITH IL-2, A THERAPEUTIC ANTIBODY, AND...
- Publication number 20170224777
- Publication date Aug 10, 2017
- Massachusetts Institute of Technology
- Karl Dane WITTRUP
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SYNERGISTIC TUMOR TREATMENT WITH IL-2, A THERAPEUTIC ANTIBODY, AND...
- Publication number 20170216403
- Publication date Aug 3, 2017
- Massachusetts Institute of Technology
- Karl Dane WITTRUP
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

KARL DANE WITTRUP

Person

Patents Grantslast 30 patents

Combination immunotherapy for treatment of melanoma, colon or non-s...

Polyclonal mixtures of antibodies, and methods of making and using...

Collagen-localized immunomodulatory molecules and methods thereof

Bispecific antibodies specific for treating hematological malignancies

Multi-specific antibodies with affinity for human A33 antigen and D...

Synthetic oncolytic LNP-replicon RNA and uses for cancer immunotherapy

Immunomodulatory fusion protein-metal hydroxide complexes and metho...

Multiple specificity binders of CXC chemokines

Monoclonal antibodies that bind human CD161

Methods to specifically profile protease activity at lymph nodes

Polyclonal mixtures of antibodies, and methods of making and using...

Combination immunotherapy dosing regimen for immune checkpoint bloc...

Synergistic tumor treatment with an extended pharmacokinetic IL-2 a...

Multi-specific antibodies with affinity for human A33 antigen and D...

Methods of treating cancer cells expressing tumor-associated integrins

Polyclonal mixtures of antibodies, and methods of making and using...

Combination tumor treatment with an integrin-binding-Fc fusion prot...

Method of treating cancer with a multiple integrin binding Fc fusio...

Synergistic tumor treatment with antibodies targeting PD-1, PD-L1 o...

Synergistic tumor treatment with extended-PK IL-2 and therapeutic a...

Antibody-based constructs directed against tyrosine kinase receptors

Engineered proteins with high affinity for DOTA chelates

Cell display libraries

Mutant interleukin-2 (IL-2) polypeptides

Patents Applicationslast 30 patents

LUNG-CANCER SPECIFIC T CELL DYSFUNCTION

SYNTHETIC ONCOLYTIC LNP-REPLICON RNA AND USES FOR CANCER IMMUNOTHERAPY

IMMUNOMODULATORY FUSION PROTEIN-METAL HYDROXIDE COMPLEXES AND METHO...

ENHANCED-AFFINITY ANTI-ECM NANOBODY-CYTOKINE FUSIONS AND THEIR APPL...

COLLAGEN-LOCALIZED IMMUNOMODULATORY MOLECULES AND METHODS THEREOF

POLYCLONAL MIXTURES OF ANTIBODIES, AND METHODS OF MAKING AND USING...

METHODS TO SPECIFICALLY PROFILE PROTEASE ACTIVITY AT LYMPH NODES

FUSION POLYPEPTIDES

SYNERGISTIC TUMOR TREATMENT WITH IL-2 AND INTEGRIN-BINDING-FC FUSIO...

COMBINATION IMMUNOTHERAPY DOSING REGIMEN FOR IMMUNE CHECKPOINT BLOC...

METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS...

CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF

MULTI-SPECIFIC ANTIBODIES WITH AFFINITY FOR HUMAN A33 ANTIGEN AND D...

MULTIPLE SPECIFICITY BINDERS OF CXC CHEMOKINES AND USES THEREOF

BISPECIFIC ANTIBODY COMPOSITIONS AND RELATED METHODS FOR IMPROVED P...

MONOCLONAL ANTIBODIES THAT BIND HUMAN CD161 AND USES THEREOF

COMBINATION TUMOR TREATMENT WITH AN INTEGRIN-BINDING-FC FUSION PROT...

IMMUNOMODULATORY FUSION PROTEIN-METAL HYDROXIDE COMPLEXES AND METHO...

SYNTHETIC ONCOLYTIC LNP-REPLICON RNA AND USES FOR CANCER IMMUNOTHERAPY

POLYCLONAL MIXTURES OF ANTIBODIES, AND METHODS OF MAKING AND USING...

COMBINATION IMMUNOTHERAPY DOSING REGIMEN FOR IMMUNE CHECKPOINT BLOC...

MULTI-SPECIFIC ANTIBODIES WITH AFFINITY FOR HUMAN A33 ANTIGEN AND D...

COLLAGEN-LOCALIZED IMMUNOMODULATORY MOLECULES AND METHODS THEREOF

SYNERGISTIC TUMOR TREATMENT WITH IL-2 AND INTEGRIN-BINDING-FC FUSIO...

METHODS TO SPECIFICALLY PROFILE PROTEASE ACTIVITY AT LYMPH NODES

SYNERGISTIC TUMOR TREATMENT WITH IL-2, AN INTEGRIN-BINDING-FC FUSIO...

COMBINATION TUMOR TREATMENT WITH AN INTEGRIN-BINDING-FC FUSION PROT...

PROTEIN-CHAPERONED T-CELL VACCINES

SYNERGISTIC TUMOR TREATMENT WITH IL-2, A THERAPEUTIC ANTIBODY, AND...

SYNERGISTIC TUMOR TREATMENT WITH IL-2, A THERAPEUTIC ANTIBODY, AND...