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Kiel Lazarski
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Watertown, MA, US
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Patents Grants
last 30 patents
Information
Patent Grant
Isoindolinone derivatives as selective allosteric inhibitors of Egf...
Patent number
12,209,091
Issue date
Jan 28, 2025
HOFFMANN-LA ROCHE INC.
Martin Duplessis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Macrocyclic fluorine substituted indole derivatives
Patent number
12,152,041
Issue date
Nov 26, 2024
The Broad Institute, Inc.
Steven James Ferrara
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Spirocyclic degronimers for target protein degradation
Patent number
12,048,748
Issue date
Jul 30, 2024
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted piperidine Degronimers for Target Protein degradation
Patent number
12,048,747
Issue date
Jul 30, 2024
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
C3-carbon linked glutarimide degronimers for target protein degrada...
Patent number
11,992,531
Issue date
May 28, 2024
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted macrocyclic indole derivatives
Patent number
11,891,404
Issue date
Feb 6, 2024
Bayer Aktiengesellschaft
Kai Thede
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
2-benzopyrazinyl-n-heteroaryl-2-phenyl-acetamide compounds
Patent number
11,708,354
Issue date
Jul 25, 2023
HOFFMANN-LA ROCHE INC.
Martin Duplessis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Isoindolinone and indazole compounds for the degradation of EGFR
Patent number
11,673,902
Issue date
Jun 13, 2023
C4 Therapeutics, Inc.
Christopher G. Nasveschuk
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Degraders and Degrons for targeted protein degradation
Patent number
11,524,949
Issue date
Dec 13, 2022
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Macrocyclic indole derivatives
Patent number
11,492,358
Issue date
Nov 8, 2022
The Broad Institute, Inc.
Sarah Anna Liesa Johannes
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Macrocyclic chlorine substituted indole derivatives
Patent number
11,478,451
Issue date
Oct 25, 2022
Bayer Aktiengesellschaft
Kai Thede
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Macrocyclic chlorine substituted indole derivatives
Patent number
11,447,504
Issue date
Sep 20, 2022
Bayer Aktiengesellschaft
Kai Thede
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted macrocyclic indole derivatives
Patent number
11,440,923
Issue date
Sep 13, 2022
Kai Thede
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Macrocyclic indole derivatives
Patent number
11,401,278
Issue date
Aug 2, 2022
The Broad Institute, Inc.
Laura Furst
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Macrocyclic fluorine substituted indole derivatives
Patent number
11,286,263
Issue date
Mar 29, 2022
The Broad Institute, Inc.
Steven James Ferrara
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Spirocyclic degronimers for target protein degradation
Patent number
11,185,592
Issue date
Nov 30, 2021
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Macrocyclic indole derivatives
Patent number
10,981,932
Issue date
Apr 20, 2021
Bayer Aktiengesellschaft
Sarah Anna Liesa Johannes
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
2-benzopyrazinyl-n-heteroaryl-2-phenyl-acetamide compounds
Patent number
10,882,848
Issue date
Jan 5, 2021
Hoffmann-La Roche, Inc.
Martin Duplessis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
C3-carbon linked glutarimide degronimers for target protein degrada...
Patent number
10,849,982
Issue date
Dec 1, 2020
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Spirocyclic degronimers for target protein degradation
Patent number
10,660,968
Issue date
May 26, 2020
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
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Patent Application
C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADA...
Publication number
20240398959
Publication date
Dec 5, 2024
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
EGFR Degraders to Treat Cancer Metastasis to the Brain or CNS
Publication number
20240158418
Publication date
May 16, 2024
C4 Therapeutics, Inc.
Christopher G. Nasveschuk
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR
Publication number
20240076300
Publication date
Mar 7, 2024
C4 Therapeutics, Inc.
Christopher G. Nasveschuk
C07 - ORGANIC CHEMISTRY
Information
Patent Application
DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION
Publication number
20230357180
Publication date
Nov 9, 2023
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
COMPOUNDS FOR TARGETED DEGRADATION OF RET
Publication number
20230233692
Publication date
Jul 27, 2023
C4 Therapeutics, Inc.
James A. Henderson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SUBSTITUTED MACROCYCLIC INDOLE DERIVATIVES
Publication number
20230112244
Publication date
Apr 13, 2023
Bayer Aktiengesellschaft
Kai Thede
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR
Publication number
20230110648
Publication date
Apr 13, 2023
C4 Therapeutics, Inc.
Christopher G. Nasveschuk
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20230095223
Publication date
Mar 30, 2023
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER
Publication number
20230024096
Publication date
Jan 26, 2023
HOFFMANN-LA ROCHE INC.
Martin DUPLESSIS
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIFUNCTIONAL COMPOUNDS
Publication number
20230002367
Publication date
Jan 5, 2023
HOFFMANN-LA ROCHE INC.
Delphine GAUFRETEAU
C07 - ORGANIC CHEMISTRY
Information
Patent Application
C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADA...
Publication number
20220313826
Publication date
Oct 6, 2022
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED PIPERIDINE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20220313827
Publication date
Oct 6, 2022
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MACROCYCLIC FLUORINE SUBSTITUTED INDOLE DERIVATIVES
Publication number
20220281891
Publication date
Sep 8, 2022
THE BROAD INSTITUTE, INC.
Steven J. Ferrara
C07 - ORGANIC CHEMISTRY
Information
Patent Application
DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION
Publication number
20220251061
Publication date
Aug 11, 2022
C4 Therapeutics, Inc.
Andrew J. Phillips
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MACROCYCLIC INDOLE DERIVATIVES
Publication number
20210292341
Publication date
Sep 23, 2021
THE BROAD INSTITUTE, INC.
Laura Furst
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MACROCYCLIC CHLORINE SUBSTITUTED INDOLE DERIVATIVES
Publication number
20210277022
Publication date
Sep 9, 2021
Bayer Aktiengesellschaft
Kai Thede
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED MACROCYCLIC INDOLE DERIVATIVES
Publication number
20210269456
Publication date
Sep 2, 2021
Bayer Aktiengesellschaft
Kai Thede
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ARYL ANNULATED MACROCYCLIC INDOLE DERIVATIVES
Publication number
20210253598
Publication date
Aug 19, 2021
Bayer Aktiengesellschaft
Kai Thede
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20210106688
Publication date
Apr 15, 2021
C4 Therapeutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOUNDS
Publication number
20210079005
Publication date
Mar 18, 2021
HOFFMANN-LA ROCHE INC.
Martin Duplessis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MACROCYCLIC FLUORINE SUBSTITUTED INDOLE DERIVATIVES
Publication number
20210079018
Publication date
Mar 18, 2021
THE BROAD INSTITUTE, INC.
Steven J. Ferrara
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
2-BENZOPYRAZINYL-N-HETEROARYL-2-PHENYL-ACETAMIDE COMPOUNDS
Publication number
20210070739
Publication date
Mar 11, 2021
HOFFMANN-LA ROCHE INC.
Martin Duplessis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIFUNCTIONAL MOLECULES THAT DEGRADE EGFR
Publication number
20200361930
Publication date
Nov 19, 2020
HOFFMANN-LA ROCHE INC.
Martin Duplessis
C07 - ORGANIC CHEMISTRY
Information
Patent Application
BIFUNCTIONAL INHIBITORS WITH EGFR HAVING A E3 UBIQUITIN LIGASE MOIETY
Publication number
20200308171
Publication date
Oct 1, 2020
HOFFMANN-LA ROCHE INC.
Georg Jaeschke
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MACROCYCLIC INDOLE DERIVATIVES
Publication number
20200087322
Publication date
Mar 19, 2020
Sarah Anna Liesa Johannes
C07 - ORGANIC CHEMISTRY
Information
Patent Application
2-BENZOPYRAZINYL-N-HETEROARYL-2-PHENYL-ACETAMIDE COMPOUNDS
Publication number
20190308955
Publication date
Oct 10, 2019
HOFFMANN-LA ROCHE INC.
Martin Duplessis
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20190076539
Publication date
Mar 14, 2019
C4 Theraprutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
C3-CARBON LINKED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADA...
Publication number
20190076542
Publication date
Mar 14, 2019
C4 Theraprutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
Publication number
20190076540
Publication date
Mar 14, 2019
C4 Theraprutics, Inc.
Andrew J. Phillips
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE