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Larry K. Keefer
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Bethesda, MD, US
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Patents Grants
last 30 patents
Information
Patent Grant
Nitric oxide-releasing diazeniumdiolated polyvinylpyrrolidone-based...
Patent number
9,540,471
Issue date
Jan 10, 2017
The United States of America, as represented by the Secretary, Department of...
Joseph A. Hrabie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Diazeniumdiolated compounds, pharmaceutical compositions, and metho...
Patent number
9,205,091
Issue date
Dec 8, 2015
The United States of America, as represented by the Secretary Department of H...
Anna E. Maciag
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Hybrid diazeniumdiolated compounds, pharmaceutical compositions, an...
Patent number
9,168,266
Issue date
Oct 27, 2015
The United States of America, as represented by the Secretary, Department of...
Anna E. Maciag
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Nitroxyl (HNO) releasing compounds and uses thereof in treating dis...
Patent number
8,633,177
Issue date
Jan 21, 2014
The United States of America, as represented by the Secretary, Department of...
Katrina M. Miranda
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitric oxide-releasing diazeniumdiolated compounds
Patent number
8,093,343
Issue date
Jan 10, 2012
The United States of America, as represented by the Secretary, Department of...
Joseph A. Hrabie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polyme...
Patent number
7,968,664
Issue date
Jun 28, 2011
The United States of America as represented by the Department of Health and H...
Joseph A. Hrabie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Polydiazeniumdiolated cyclic polyamines with polyphasic nitric oxid...
Patent number
7,928,096
Issue date
Apr 19, 2011
The United States of America, as represented by the Secretary, Department of...
David J. Waterhouse
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Polysaccharide-derived nitric oxide-releasing carbon-bound diazeniu...
Patent number
7,928,079
Issue date
Apr 19, 2011
The United States of America, as represented by the Secretary, Department of...
Joseph A. Hrabie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods for separation and detection of ketosteroids and other carb...
Patent number
7,807,472
Issue date
Oct 5, 2010
The United States of America as represented by the Department of Health and H...
Xia Xu
G01 - MEASURING TESTING
Information
Patent Grant
Polydiazeniumdiolated cyclic polyamines with polyphasic nitric oxid...
Patent number
7,468,435
Issue date
Dec 23, 2008
The United States of America as represented by the Department of Health and H...
David J. Waterhouse
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitric oxide-releasing medical devices
Patent number
7,425,218
Issue date
Sep 16, 2008
The United States of America as represented by the Department of Health and H...
Larry K. Keefer
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Nitric oxide-releasing amidine diazeniumdiolates, compositions and...
Patent number
7,348,319
Issue date
Mar 25, 2008
United States of America as represented by the Department of Health and Human...
Joseph A Hrabie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Highly cross-linked, extremely hydrophobic nitric oxide-releasing p...
Patent number
7,226,586
Issue date
Jun 5, 2007
Medtronic Vascular, Inc.
Anthony L. Fitzhugh
C08 - ORGANIC MACROMOLECULAR COMPOUNDS THEIR PREPARATION OR CHEMICAL WORKING-...
Information
Patent Grant
Nitric oxide-releasing imidate and thioimidate diazeniumdiolates
Patent number
7,105,502
Issue date
Sep 12, 2006
The United States of America as represented by the Department of Health and H...
Ernst V Arnold
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
O2-substituted 1-[(2-carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-d...
Patent number
7,081,524
Issue date
Jul 25, 2006
The United States of America as represented by the Department of Health and H...
Joseph E Saavedra
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitric oxide-releasing amidine diazeniumdiolates, compositions and...
Patent number
6,949,530
Issue date
Sep 27, 2005
The United States of America as represented by the Department of Health and H...
Joseph A. Hrabie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
O2-glycosylated 1-substituted diazen-1-ium-1,2-diolates
Patent number
6,911,433
Issue date
Jun 28, 2005
The United States of America as represented by the Department of Health and H...
Joseph E. Saavedra
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolat...
Patent number
6,911,478
Issue date
Jun 28, 2005
The United States of America as represented by the Department of Health and H...
Joseph A. Hrabie
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitric oxide-releasing metallic medical devices
Patent number
6,887,485
Issue date
May 3, 2005
Medtronic Vascular, Inc.
Anthony L. Fitzhugh
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Nitric oxide-releasing amidine—and enamine-derived diazeniu...
Patent number
6,750,254
Issue date
Jun 15, 2004
The United States of America as represented by the Department of Health and H...
Joseph A. Hrabie
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Highly cross-linked, extremely hydrophobic nitric oxide-releasing p...
Patent number
6,703,046
Issue date
Mar 9, 2004
Medtronic AVE Inc.
Anthony L. Fitzhugh
C08 - ORGANIC MACROMOLECULAR COMPOUNDS THEIR PREPARATION OR CHEMICAL WORKING-...
Information
Patent Grant
Nitric oxide-releasing imidate and thioimidate diazeniumdiolates, c...
Patent number
6,673,338
Issue date
Jan 6, 2004
The United States of America as represented by the Department of Health and H...
Ernst V. Arnold
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
O2-arylated or O2-glycosylated 1-substituted diazen-1-ium-1,2-diola...
Patent number
6,610,660
Issue date
Aug 26, 2003
The United States of America as represented by the Department of Health and H...
Joseph E. Saavedra
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolat...
Patent number
6,511,991
Issue date
Jan 28, 2003
The United States of America as represented by the Department of Health and H...
Joseph A. Hrabie
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Nitric oxide-releasing 1-[(2-carboxylato)pyrrolidin-1-yl&#x...
Patent number
6,379,660
Issue date
Apr 30, 2002
The United States of America as represented by the Secretary of the Departmen...
Joseph E. Saavedra
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Use of nitric oxide-releasing agents to treat impotency
Patent number
6,290,981
Issue date
Sep 18, 2001
The United States of America as represented by the Department of Health and H...
Larry K. Keefer
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Nitric oxide-releasing metallic medical devices
Patent number
6,270,779
Issue date
Aug 7, 2001
United States of America
Anthony L. Fitzhugh
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolat...
Patent number
6,232,336
Issue date
May 15, 2001
The United States of America as represented by the Department of Health and H...
Joseph A. Hrabie
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Biopolymer-bound nitric oxide-releasing compositions, pharmaceutica...
Patent number
6,200,558
Issue date
Mar 13, 2001
The United States of America as represented by the Department of Health and H...
Joseph E. Saavedra
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Polymer-bound nitric oxide/nucleophile adduct compositions, pharmac...
Patent number
6,110,453
Issue date
Aug 29, 2000
The United States of America as represented by the Department of Health and H...
Larry K. Keefer
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED POLYVINYLPYRROLIDONE-BASED...
Publication number
20150166706
Publication date
Jun 18, 2015
The United States of America, as represented by the Secretary, Department of
Joseph A. Hrabie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
HYBRID DIAZENIUMDIOLATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AN...
Publication number
20140315865
Publication date
Oct 23, 2014
Anna E. Maciag
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
NITROXYL (HNO) RELEASING COMPOUNDS AND USES THEREOF IN TREATING DIS...
Publication number
20130065863
Publication date
Mar 14, 2013
THE ARIZONA BOARD OF REGENTS, on behalf of THE UNIVERSITY OF ARIZONA
Katrina M. Miranda
C07 - ORGANIC CHEMISTRY
Information
Patent Application
DIAZENIUMDIOLATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHO...
Publication number
20120238518
Publication date
Sep 20, 2012
The United States of America, as Represented by the Secretary, Dept. of Healt...
Anna E. Maciag
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED COMPOUNDS
Publication number
20110282060
Publication date
Nov 17, 2011
The United States of America, as represented by the Secretary, Department of...
Joseph A. Hrabie
C08 - ORGANIC MACROMOLECULAR COMPOUNDS THEIR PREPARATION OR CHEMICAL WORKING-...
Information
Patent Application
DIAZENIUMDIOLATED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS, COMPOSITIO...
Publication number
20090186859
Publication date
Jul 23, 2009
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SEC., DEPT. OF HEALTH AND...
Carlos A. Velázquez
C07 - ORGANIC CHEMISTRY
Information
Patent Application
POLYDIAZENIUMDIOLATED CYCLIC POLYAMINES WITH POLYPHASIC NITRIC OXID...
Publication number
20090068248
Publication date
Mar 12, 2009
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HE
David J. Waterhouse
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Polysaccharide-Derived Nitric Oxide-Releasing Carbon-Bound Diazeniu...
Publication number
20080306012
Publication date
Dec 11, 2008
GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRES ENTED BY THE SECRETARY OF...
Joseph A. Hrabie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Nitric Oxide-Releasing Diazeniumdiolated Acrylonitrile-Based Polyme...
Publication number
20070292471
Publication date
Dec 20, 2007
The Government of the United States of America, as Represented by the Secreta...
Joseph A. Hrabie
C08 - ORGANIC MACROMOLECULAR COMPOUNDS THEIR PREPARATION OR CHEMICAL WORKING-...
Information
Patent Application
Analysis of large numbers of estrogens and other steroids and appli...
Publication number
20070004045
Publication date
Jan 4, 2007
Xia Xu
G01 - MEASURING TESTING
Information
Patent Application
Novel nitric oxide-releasing amidine diazeniumdiolates, composition...
Publication number
20050288260
Publication date
Dec 29, 2005
Government of the United States of America, represented by the Secretary, Dep...
Joseph A. Hrabie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
O2-substituted 1-[(2-carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-d...
Publication number
20050214249
Publication date
Sep 29, 2005
Government of the USA, represented by the Secretary, HHS
Joseph E. Saavedra
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Methods for separation and detection of ketosteroids and other carb...
Publication number
20050181514
Publication date
Aug 18, 2005
Xia Xu
G01 - MEASURING TESTING
Information
Patent Application
Polydiazeniumdiolated cyclic polyamines with polyphasic nitric oxid...
Publication number
20050148566
Publication date
Jul 7, 2005
The Government of the USA, as Rep. by the Secretary, Dept. of Health & Human...
David J. Waterhouse
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Highly cross-linked, extremely hydrophobic nitric oxide-releasing p...
Publication number
20050079148
Publication date
Apr 14, 2005
Anthony L. Fitzhugh
C08 - ORGANIC MACROMOLECULAR COMPOUNDS THEIR PREPARATION OR CHEMICAL WORKING-...
Information
Patent Application
Novel, nitric oxide-releasing amidine- and enamine-derived diazeniu...
Publication number
20040180863
Publication date
Sep 16, 2004
Govt. of the USA, rep. by the Secretary, Dept. of Health & Human Servs., Offi...
Joseph A. Hrabie
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Novel nitric oxide-releasing imidate and thioimidate diazeniumdiola...
Publication number
20040092484
Publication date
May 13, 2004
Government of the United States of America, represented by the Secretary, Dep...
Ernst V. Arnold
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Novel nitric oxide-releasing amidine diazeniumdiolates, composition...
Publication number
20040014720
Publication date
Jan 22, 2004
Government of the United States of America, represented by the Secretary
Joseph A. Hrabie
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Novel nitric oxide-releasing amidine- and enamine-derived diazenium...
Publication number
20030166619
Publication date
Sep 4, 2003
Government of the U.S.A., represented by the Secretary of Dept. of Health and...
Joseph A. Hrabie
C07 - ORGANIC CHEMISTRY
Information
Patent Application
O2-arylated or O2-glycosylated 1-substituted diazen-1-ium-1,2-diola...
Publication number
20030147845
Publication date
Aug 7, 2003
Government of the USA, the Secretary Department of Health and Human Services
Joseph E. Saavedra
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Highly cross-linked, extremely hydrophobic nitric oxide-releasing p...
Publication number
20030077243
Publication date
Apr 24, 2003
Anthony L. Fitzhugh
C08 - ORGANIC MACROMOLECULAR COMPOUNDS THEIR PREPARATION OR CHEMICAL WORKING-...
Information
Patent Application
Nitric oxide-releasing medical devices
Publication number
20020119115
Publication date
Aug 29, 2002
Office of Technology Transfer, National Institutes of Health
Larry K. Keefer
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Nitric oxide-releasing metallic medical devices
Publication number
20010041184
Publication date
Nov 15, 2001
Anthony L. Fitzhugh
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Novel nitric oxide-releasing amidine- and enamine-derived diazenium...
Publication number
20010025052
Publication date
Sep 27, 2001
Joseph A. Hrabie
C07 - ORGANIC CHEMISTRY