Membership
Tour
Register
Log in
Mark E. Layton
Follow
Person
Harleysville, PA, US
People
Overview
Industries
Organizations
People
Information
Impact
Patents Grants
last 30 patents
Information
Patent Grant
2-oxoimidazolidine-4-carboxamides as NAv1.8 inhibitors
Patent number
11,802,122
Issue date
Oct 31, 2023
Merck Sharp & Dohme LLC
Ashok Arasappan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
2-amino-n-heteroaryl-nicotinamides as Nav1.8 inhibitors
Patent number
11,377,438
Issue date
Jul 5, 2022
Merck Sharp & Dohme LLC
Ashok Arasappan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Diamino-alkylamino-linked arylsulfonamide compounds with selective...
Patent number
10,968,210
Issue date
Apr 6, 2021
Merck Sharp & Dohme Corp.
Thomas J. Greshock
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Diamino-alkylamino-linked arylsulfonamide compounds with selective...
Patent number
10,519,147
Issue date
Dec 31, 2019
Merck Sharp & Dohme Corp.
Thomas J. Greshock
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
N1-phenylpropane-1,2-diamine compounds with selective activity in v...
Patent number
10,442,778
Issue date
Oct 15, 2019
Merck Sharp & Dohme Corp.
Anthony J. Roecker
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Benzoxazolinone compounds with selective activity in voltage-gated...
Patent number
9,624,208
Issue date
Apr 18, 2017
Merck Sharp & Dohme Corp.
Joseph E. Pero
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bicycloamine-substituted-N-benzenesulfonamide compounds with select...
Patent number
9,586,968
Issue date
Mar 7, 2017
Merck Sharp & Dohme Corp.
Mark E. Layton
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
N-substituted indazole sulfonamide compounds with selective activit...
Patent number
9,388,179
Issue date
Jul 12, 2016
Merck Sharp & Dohme Corp.
Joseph E. Pero
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Imidazopyridin-2-one derivatives
Patent number
9,315,518
Issue date
Apr 19, 2016
Merck Sharp & Dohme Corp.
Hannah D. Fiji
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Benzoxazolinone compounds with selective activity in voltage-gated...
Patent number
9,273,040
Issue date
Mar 1, 2016
Merck Sharp & Dohme Corp.
Mark E. Layton
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Positive allosteric modulators of mGluR2
Patent number
9,108,937
Issue date
Aug 18, 2015
Merck Sharp & Dohme Corp.
Mark E. Layton
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pyrimidine PDE10 inhibitors
Patent number
9,062,059
Issue date
Jun 23, 2015
Merck Sharp & Dohme Corp.
Christopher D. Cox
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Positive allosteric modulators of MGLUR2
Patent number
8,993,779
Issue date
Mar 31, 2015
Merck Sharp & Dohme Corp.
Vadim Y. Dudkin
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted 1,3-benzothiazol-2(3H)-ones and [1,3]thiazolo[5,4-B]pyr...
Patent number
8,952,005
Issue date
Feb 10, 2015
Merck Sharp & Dohme Corp.
Mark E. Layton
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Positive allosteric modulators of MGLUR2
Patent number
8,765,784
Issue date
Jul 1, 2014
Merck Sharp & Dohme Corp.
Kenneth L. Arrington
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibitors of AKT activity
Patent number
8,536,193
Issue date
Sep 17, 2013
Merck Sharp & Dohme Corp.
Hidetomo Furuyama
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Combination cancer therapy with an AKT inhibitor and other anticanc...
Patent number
8,481,503
Issue date
Jul 9, 2013
Merck Sharp & Dohme Corp.
Mark E. Layton
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted naphthyridine compounds as inhibitors of Akt activity
Patent number
8,288,407
Issue date
Oct 16, 2012
Merck Sharp & Dohme Corp.
Michael J. Kelly, III
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted [1,2,4]triazolo[4′,3′:1,6]pyrido[2,3-b]pyrazines of the...
Patent number
8,207,169
Issue date
Jun 26, 2012
MSD K.K.
Hidetomo Furuyama
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibitors of AKT activity
Patent number
8,168,652
Issue date
May 1, 2012
Merck Sharp & Dohme Corp.
Philip E. Sanderson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Inhibitors of akt activtiy
Patent number
8,008,317
Issue date
Aug 30, 2011
Merck Sharp & Dohme Corp.
Donna J. Armstrong
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibitors of Akt activity
Patent number
7,910,561
Issue date
Mar 22, 2011
Merck Sharp & Dohme Corp.
Jeannie M. Arruda
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibitors of Akt activity
Patent number
7,589,068
Issue date
Sep 15, 2009
Merck & Co., Inc.
Nicholas D. P. Cosford
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Inhibitors of Akt activity
Patent number
7,576,209
Issue date
Aug 18, 2009
Merck & Co., Inc.
Michael J. Kelly, III
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
4-cycloakylaminopyrazolo pyrimidine NMDA/NR2B antagonists
Patent number
7,452,893
Issue date
Nov 18, 2008
Merck & Co., Inc.
Wayne Thompson
C07 - ORGANIC CHEMISTRY
Patents Applications
last 30 patents
Information
Patent Application
2-OXO-IMIDAZOLIDINE-4-CARBOXAMIDES AS NAV1.8 INHIBITORS
Publication number
20230312528
Publication date
Oct 5, 2023
Merck Sharp & Dohme LLC
Ashok Arasappan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
5-OXOPYRROLIDINE-3-CARBOXAMIDES AS NAV1.8 INHIBITORS
Publication number
20230227405
Publication date
Jul 20, 2023
Merck Sharp & Dohme LLC
Ashok Arasappan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
2-OXO-OXAZOLIDINE-5-CARBOXAMIDES AS NAV1.8 INHIBITORS
Publication number
20230227441
Publication date
Jul 20, 2023
Merck Sharp & Dohme LLC
Ashok Arasappan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CYCLOALKYL 3-OXOPIPERAZINE CARBOXAMIDES AND CYCLOHETEROALKYL 3-OXOP...
Publication number
20220380338
Publication date
Dec 1, 2022
Merck Sharp & Dohme LLC
Ashok Arasappan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
HYDROXYPYRROLIDINE-SUBSTITUTED ARYLSULFONAMIDE COMPOUNDS WITH SELEC...
Publication number
20220305035
Publication date
Sep 29, 2022
MERCK SHARP & DOHME CORP.
Anthony J. Roecker
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
2-AMINO-N-HETEROARYL-NICOTINAMIDES AS NAV1.8 INHIBITORS
Publication number
20220289710
Publication date
Sep 15, 2022
Merck Sharp & Dohme LLC
Ashok Arasappan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
2-AMINO-N-PHENYL-NICOTINAMIDES AS NAV1.8 INHIBITORS
Publication number
20220119363
Publication date
Apr 21, 2022
MERCK SHARP & DOHME CORP.
Michael J. Breslin
C07 - ORGANIC CHEMISTRY
Information
Patent Application
4-AMINO OR 4-ALKOXY-SUBSTITUTED ARYL SULFONAMIDE COMPOUNDS WITH SEL...
Publication number
20220000844
Publication date
Jan 6, 2022
MERCK SHARP & DOHME CORP.
Christopher J. Bungard
C07 - ORGANIC CHEMISTRY
Information
Patent Application
2-OXOIMIDAZOLIDINE-4-CARBOXAMIDES AS NAV1.8 INHIBITORS
Publication number
20210403457
Publication date
Dec 30, 2021
MERCK SHARP & DOHME CORP.
Ashok Arasappan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
2-AMINO-N-HETEROARYL-NICOTINAMIDES AS NAV1.8 INHIBITORS
Publication number
20210387966
Publication date
Dec 16, 2021
MERCK SHARP & DOHME CORP.
Ashok Arasappan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
2-AMINO-N-HETEROARYL-NICOTINAMIDES AS NAV1.8 INHIBITORS
Publication number
20200140411
Publication date
May 7, 2020
MERCK SHARP & DOHME CORP.
Ashok Arasappan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
DIAMINO-ALKYLAMINO-LINKED ARYLSULFONAMIDE COMPOUNDS WITH SELECTIVE...
Publication number
20200131167
Publication date
Apr 30, 2020
MERCK SHARP & DOHME CORP.
Thomas J. Greshock
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N1-PHENYLPROPANE-1,2-DIAMINE COMPOUNDS WITH SELECTIVE ACTIVITY IN V...
Publication number
20190092738
Publication date
Mar 28, 2019
Merck Sharp & Dohme Corp.
Anthony J. Roecker
C07 - ORGANIC CHEMISTRY
Information
Patent Application
DIAMINO-ALKYLAMINO-Linked ARYLSULFONAMIDE COMPOUNDS WITH SELECTIVE...
Publication number
20180362518
Publication date
Dec 20, 2018
MERCK SHARP & DOHME CORP.
Thomas J. Greshock
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BICYCLOAMINE-SUBSTITUTED-N-BENZENESULFONAMIDE COMPOUNDS WITH SELECT...
Publication number
20170002008
Publication date
Jan 5, 2017
MERCK SHARP & DOHME CORP.
Mark E. Layton
C07 - ORGANIC CHEMISTRY
Information
Patent Application
N-SUBSTITUTED INDAZOLE SULFONAMIDE COMPOUNDS WITH SELECTIVE ACTIVIT...
Publication number
20150284389
Publication date
Oct 8, 2015
MERCK SHARP & DOHME CORP.
Joseph E. Pero
C07 - ORGANIC CHEMISTRY
Information
Patent Application
BENZOXAZOLINONE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED...
Publication number
20150252034
Publication date
Sep 10, 2015
Joseph E. Pero
C07 - ORGANIC CHEMISTRY
Information
Patent Application
IMIDAZOPYRIDIN-2-ONE DERIVATIVES
Publication number
20140350002
Publication date
Nov 27, 2014
MERCK SHARP & DOHME CORP.
Hannah D. Fiji
C07 - ORGANIC CHEMISTRY
Information
Patent Application
BENZOXAZOLINONE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED...
Publication number
20140303143
Publication date
Oct 9, 2014
Mark E. Layton
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRIMIDINE PDE10 INHIBITORS
Publication number
20140228368
Publication date
Aug 14, 2014
Christopher D. Cox
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SUBSTITUTED 1,3-BENZOTHIAZOL-2(3H)-ONES AND [1,3]THIAZOLO[5,4-B]PYR...
Publication number
20140045829
Publication date
Feb 13, 2014
MERCK SHARP & DOHME CORP.
MARK E. LAYTON
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
POSITIVE ALLOSTERIC MODULATORS OF MGLUR2
Publication number
20130210768
Publication date
Aug 15, 2013
Kenneth L. Arrington
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ISOINDOLINE PDE10 INHIBITORS
Publication number
20130203756
Publication date
Aug 8, 2013
Jamie L. Bunda
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
POSITIVE ALLOSTERIC MODULATORS OF MGLUR2
Publication number
20130158002
Publication date
Jun 20, 2013
Mark E. Layton
C07 - ORGANIC CHEMISTRY
Information
Patent Application
POSITIVE ALLOSTERIC MODULATORS OF MGLUR2
Publication number
20130143880
Publication date
Jun 6, 2013
Vadim Y. Dudkin
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Substituted 1,3-Benzothiazol-2(3H)-Ones and [1,3]Thiazolo[5,4-B]Pyr...
Publication number
20130035332
Publication date
Feb 7, 2013
Mark E. Layton
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
INHIBITORS OF AKT ACTIVITY
Publication number
20120252806
Publication date
Oct 4, 2012
Michael J. Kelly, III
C07 - ORGANIC CHEMISTRY
Information
Patent Application
INHIBITORS OF AKT ACTIVITY
Publication number
20110319443
Publication date
Dec 29, 2011
Philip E. Sanderson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Combination Cancer Therapy with an AKT Inhibitor and Other Anticanc...
Publication number
20110319354
Publication date
Dec 29, 2011
Mark E. Layton
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Inhibitors of AKT Activity
Publication number
20110288090
Publication date
Nov 24, 2011
Donna J. Armstrong
C07 - ORGANIC CHEMISTRY