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Mark W. Holladay
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Vernon Hills, IL, US
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Patents Grants
last 30 patents
Information
Patent Grant
Compounds and methods for kinase modulation, and indications therefor
Patent number
10,829,484
Issue date
Nov 10, 2020
Plexxikon Inc.
Mark W. Holladay
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Heterocyclic compounds and methods of use thereof
Patent number
9,938,261
Issue date
Apr 10, 2018
Ambit Biosciences Corporation
Michael J. Hadd
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
RAF kinase modulator compounds and methods of use thereof
Patent number
9,730,937
Issue date
Aug 15, 2017
Ambit Biosciences Corporation
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Biaryl acetamide compounds and methods of use thereof
Patent number
9,725,465
Issue date
Aug 8, 2017
Ambit Biosciences Corporation
Mark W. Holladay
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Heterocyclic compounds and methods of use thereof
Patent number
9,452,167
Issue date
Sep 27, 2016
Ambit Biosciences Corporation
Michael J. Hadd
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
RAF kinase modulator compounds and methods of use thereof
Patent number
9,320,739
Issue date
Apr 26, 2016
Ambit Biosciences Corporation
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
JAK kinase modulating compounds and methods of use thereof
Patent number
9,308,207
Issue date
Apr 12, 2016
Ambit Biosciences Corp.
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Optically active pyrazolylaminoquinazoline, and pharmaceutical comp...
Patent number
9,295,672
Issue date
Mar 29, 2016
Ambit Biosciences Corporation
Mark W. Holladay
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
RAF kinase modulator compounds and methods of use thereof
Patent number
8,969,587
Issue date
Mar 3, 2015
Ambit Biosciences Corporation
Sunny Abraham
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Optically active pyrazolylaminoquinazoline, and pharmaceutical comp...
Patent number
8,952,020
Issue date
Feb 10, 2015
Ambit Biosciences Corp.
Mark W. Holladay
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Heterocyclic compounds and methods of use thereof
Patent number
8,952,058
Issue date
Feb 10, 2015
Ambit Biosciences Corporation
Michael J. Hadd
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
JAK kinase modulating compounds and methods of use thereof
Patent number
8,927,711
Issue date
Jan 6, 2015
Ambit Biosciences Corp.
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Optically active pyrazolylaminoquinazoline, and pharmaceutical comp...
Patent number
8,912,324
Issue date
Dec 16, 2014
Ambit Biosciences Corporation
Mark W. Holladay
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Optically active pyrazolylaminoquinazoline, and pharmaceutical comp...
Patent number
8,703,943
Issue date
Apr 22, 2014
Ambit Biosciences Corporation
Mark W. Holladay
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Quinazoline compounds and methods of use thereof
Patent number
8,633,207
Issue date
Jan 21, 2014
Ambit Biosciences Corporation
Michael J. Hadd
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
RAF kinase modulator compounds and methods of use thereof
Patent number
8,618,289
Issue date
Dec 31, 2013
Ambit Biosciences Corporation
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
JAK kinase modulating compounds and methods of use thereof
Patent number
8,349,851
Issue date
Jan 8, 2013
Ambit Biosciences Corp.
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Piperazine derivatives as stearoyl-coa desaturase inhibitors and th...
Patent number
8,030,488
Issue date
Oct 4, 2011
Xenon Pharmaceuticals Inc.
Serguei Sviridov
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Combination therapy
Patent number
7,919,484
Issue date
Apr 5, 2011
Xenon Pharmaceuticals Inc.
Rajender Kamboj
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Pyridazine derivatives and their use as therapeutic agents
Patent number
7,754,711
Issue date
Jul 13, 2010
Xenon Pharmaceuticals Inc.
Nagasree Chakka
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Non-nucleotide compositions and method for treating pain
Patent number
7,749,980
Issue date
Jul 6, 2010
Inspire Pharmaceuticals, Inc.
Robert Plourde, Jr.
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Piperazine derivatives and their use as therapeutic agents
Patent number
7,456,180
Issue date
Nov 25, 2008
Xenon Pharmaceuticals Inc.
Serguei Sviridov
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Pyridazine derivatives and their use as therapeutic agents
Patent number
7,335,658
Issue date
Feb 26, 2008
Xenon Pharmaceuticals Inc.
Nagasree Chakka
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Potassium channel openers
Patent number
6,645,968
Issue date
Nov 11, 2003
Abbott Laboratories
Robert J. Altenbach
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Potassium channel openers
Patent number
6,593,335
Issue date
Jul 15, 2003
Abbott Laboratories
William A. Carroll
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Tricyclic dihydropyrimidine potassium channel openers
Patent number
6,538,000
Issue date
Mar 25, 2003
Abbott Laboratories
Mark W. Holladay
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Imidazoles and related compounds as α1A agonists
Patent number
6,503,935
Issue date
Jan 7, 2003
Abbott Laboratories
Robert J. Altenbach
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-pyridyloxymethyl heterocyclic ether compounds useful in controlli...
Patent number
6,437,138
Issue date
Aug 20, 2002
Abbott Laboratories
Nan-Horng Lin
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
3-Pyridyl enantiomers and their use as analgesics
Patent number
6,403,575
Issue date
Jun 11, 2002
Abbott Laboratories
Mark W. Holladay
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Tricyclic dihydropyrimidine potassium channel openers
Patent number
6,274,587
Issue date
Aug 14, 2001
Abbott Laboratories
Mark W. Holladay
C07 - ORGANIC CHEMISTRY
Patents Applications
last 30 patents
Information
Patent Application
RAF KINASE MODULATOR COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20170298029
Publication date
Oct 19, 2017
Ambit Biosciences Corporation
Sunny ABRAHAM
C07 - ORGANIC CHEMISTRY
Information
Patent Application
COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR
Publication number
20170029413
Publication date
Feb 2, 2017
PLEXXIKON INC.
Mark W. Holladay
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20160362405
Publication date
Dec 15, 2016
Ambit Biosciences Corporation
Michael J. Hadd
C07 - ORGANIC CHEMISTRY
Information
Patent Application
RAF KINASE MODULATOR COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20160199375
Publication date
Jul 14, 2016
Ambit Biosciences Corporation
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
OPTICALLY ACTIVE PYRAZOLYLAMINOQUINAZOLINE, AND PHARMACEUTICAL COMP...
Publication number
20150353528
Publication date
Dec 10, 2015
Ambit Biosciences Corporation
Mark W. Holladay
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Application
RAF KINASE MODULATOR COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20150246042
Publication date
Sep 3, 2015
Ambit Biosciences Corporation
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20150196566
Publication date
Jul 16, 2015
Ambit Biosciences Corporation
Michael J. Hadd
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
JAK KINASE MODULATING COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20150150874
Publication date
Jun 4, 2015
Ambit Biosciences Corp.
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
OPTICALLY ACTIVE PYRAZOLYLAMINOQUINAZOLINE, AND PHARMACEUTICAL COMP...
Publication number
20150141443
Publication date
May 21, 2015
Ambit Biosciences Corp.
Mark W. HOLLADAY
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIARYL ACETAMIDE COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20150065468
Publication date
Mar 5, 2015
Ambit Biosciences Corporation
Mark W. HOLLADAY
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
OPTICALLY ACTIVE PYRAZOLYLAMINOQUINAZOLINE, AND PHARMACEUTICAL COMP...
Publication number
20140194449
Publication date
Jul 10, 2014
Ambit Biosciences Corp.
Mark W. HOLLADAY
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
RAF KINASE MODULATOR COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20140045868
Publication date
Feb 13, 2014
Ambit Biosciences Corporation
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
THIENOPYRIDINE AND THIENOPYRIMIDINE COMPOUNDS AND METHODS OF USE TH...
Publication number
20130317045
Publication date
Nov 28, 2013
Ambit Biosciences Corporation
Michael J. Hadd
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
AZOLOPYRIDINE AND AZOLOPYRIMIDINE COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20130303533
Publication date
Nov 14, 2013
Ambit Biosciences Corporation
Qi Chao
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
QUINOLINE AND ISOQUINOLINE DERIVATIVES FOR USE AS JAK MODULATORS
Publication number
20130296363
Publication date
Nov 7, 2013
Ambit Biosciences Corporation
Raffaella Faraoni
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
JAK KINASE MODULATING COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20130245014
Publication date
Sep 19, 2013
Ambit Biosciences Corp.
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
7-CYCLYLQUINAZOLINE DERIVATIVES AND METHODS OF USE THEREOF
Publication number
20130225578
Publication date
Aug 29, 2013
Ambit Biosciences Corporation
Michael J. Hadd
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20130096113
Publication date
Apr 18, 2013
Ambit Biosciences Corporation
Michael J. Hadd
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIARYL COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20130035326
Publication date
Feb 7, 2013
Ambit Biosciences Corporation
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20120053174
Publication date
Mar 1, 2012
Michael J. Hadd
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ADENOSINE A3 RECEPTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20120053176
Publication date
Mar 1, 2012
Ambit Biosciences Corp.
Robert C. Armstrong
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
OPTICALLY ACTIVE PYRAZOLYLAMINOQUINAZOLINE, AND PHARMACEUTICAL COMP...
Publication number
20120053193
Publication date
Mar 1, 2012
Ambit Biosciences Corp.
Mark W. Holladay
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
OPTICALLY ACTIVE PYRAZOLYLAMINOQUINAZOLINE, AND PHARMACEUTICAL COMP...
Publication number
20120053194
Publication date
Mar 1, 2012
Ambit Biosciences Corp.
Mark W. Holladay
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
JAK KINASE MODULATING COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20110269740
Publication date
Nov 3, 2011
Ambit Biosciences Corporation
Sunny Abraham
C07 - ORGANIC CHEMISTRY
Information
Patent Application
RAF KINASE MODULATOR COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20110118245
Publication date
May 19, 2011
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
JAK KINASE MODULATING COMPOUNDS AND METHODS OF USE THEREOF
Publication number
20100317659
Publication date
Dec 16, 2010
Sunny Abraham
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMBINATION THERAPY
Publication number
20090131447
Publication date
May 21, 2009
Xenon Pharmaceuticals Inc.
Rajender Kamboj
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS
Publication number
20090030008
Publication date
Jan 29, 2009
Xenon Pharmaceuticals Inc.
Serguei Sviridov
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Non-nucleotide compositions and method for treating pain
Publication number
20070123544
Publication date
May 31, 2007
Robert Plourde
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Pyridazine derivatives and their use as therapeutic agents
Publication number
20060009459
Publication date
Jan 12, 2006
Nagasree Chakka
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE