Michael Previte

Person

Baltimore, MD, US

People

Patents Grantslast 30 patents

Information Patent Grant
Multipart reagents having increased avidity for polymerase binding
- Patent number 12,331,356
- Issue date Jun 17, 2025
- ELEMENT BIOSCIENCES, INC.
- Sinan Arslan
- G01 - MEASURING TESTING
Information Patent Grant
Multivalent binding composition for nucleic acid analysis
- Patent number 12,313,627
- Issue date May 27, 2025
- ELEMENT BIOSCIENCES, INC.
- Sinan Arslan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Conformational probes and methods for sequencing nucleic acids
- Patent number 12,297,498
- Issue date May 13, 2025
- Illumina, Inc.
- Molly He
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Multivalent binding composition for nucleic acid analysis
- Patent number 12,241,891
- Issue date Mar 4, 2025
- ELEMENT BIOSCIENCES, INC.
- Michael Previte
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nucleotide transient binding for sequencing methods
- Patent number 12,152,256
- Issue date Nov 26, 2024
- Life Technologies Corporation
- Peter Vander Horn
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Optical systems for nucleic acid sequencing and methods thereof
- Patent number 12,146,190
- Issue date Nov 19, 2024
- ELEMENT BIOSCIENCES, INC.
- Arash Ghorbani
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for generating circular nucleic acid molecules
- Patent number 12,134,766
- Issue date Nov 5, 2024
- ELEMENT BIOSCIENCES, INC.
- Matthew Kellinger
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Multivalent binding composition for nucleic acid analysis
- Patent number 12,117,438
- Issue date Oct 15, 2024
- Sinan Arslan
- G01 - MEASURING TESTING
Information Patent Grant
Compositions and methods for pairwise sequencing
- Patent number 11,891,651
- Issue date Feb 6, 2024
- ELEMENT BIOSCIENCES, INC.
- Sinan Arslan
- G01 - MEASURING TESTING
Information Patent Grant
Compositions and methods for pairwise sequencing
- Patent number 11,859,241
- Issue date Jan 2, 2024
- ELEMENT BIOSCIENCES, INC.
- Sinan Arslan
- G01 - MEASURING TESTING
Information Patent Grant
High performance fluorescence imaging module for genomic testing assay
- Patent number 11,795,504
- Issue date Oct 24, 2023
- ELEMENT BIOSCIENCES, INC.
- Steve Xiangling Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Platform for discovery and analysis of therapeutic agents
- Patent number 11,795,581
- Issue date Oct 24, 2023
- Illumina, Inc.
- Molly He
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Grant
Methods and reagents for nucleic acid analysis
- Patent number 11,781,185
- Issue date Oct 10, 2023
- ELEMENT BIOSCIENCES, INC.
- Sinan Arslan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Conformational probes and methods for sequencing nucleic acids
- Patent number 11,643,684
- Issue date May 9, 2023
- Illumina, Inc.
- Molly He
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Polymerases, compositions, and methods of use
- Patent number 11,560,552
- Issue date Jan 24, 2023
- Illumina, Inc.
- Misha Golynskiy
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for pairwise sequencing
- Patent number 11,535,892
- Issue date Dec 27, 2022
- ELEMENT BIOSCIENCES, INC.
- Sinan Arslan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
High performance fluorescence imaging module for genomic testing assay
- Patent number 11,459,608
- Issue date Oct 4, 2022
- ELEMENT BIOSCIENCES, INC.
- Steve Xiangling Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nucleotide transient binding for sequencing methods
- Patent number 11,447,756
- Issue date Sep 20, 2022
- Life Technologies Corporation
- Peter Vander Horn
- G01 - MEASURING TESTING
Information Patent Grant
Flow cell device and use thereof
- Patent number 11,426,732
- Issue date Aug 30, 2022
- ELEMENT BIOSCIENCES, INC.
- Minghao Guo
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Grant
Compositions and methods for pairwise sequencing
- Patent number 11,427,855
- Issue date Aug 30, 2022
- ELEMENT BIOSCIENCES, INC.
- Sinan Arslan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Tube lens design for improved depth-of-field
- Patent number 11,408,032
- Issue date Aug 9, 2022
- ELEMENT BIOSCIENCES, INC.
- Steve Xiangling Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
High performance fluorescence imaging module for genomic testing assay
- Patent number 11,365,444
- Issue date Jun 21, 2022
- ELEMENT BIOSCIENCES, INC.
- Steve Xiangling Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nucleic acid sequencing systems
- Patent number 11,339,433
- Issue date May 24, 2022
- ELEMENT BIOSCIENCES, INC.
- Steve Xiangling Chen
- G01 - MEASURING TESTING
Information Patent Grant
Multivalent binding composition for nucleic acid analysis
- Patent number 11,287,422
- Issue date Mar 29, 2022
- ELEMENT BIOSCIENCES, INC.
- Michael Previte
- G01 - MEASURING TESTING
Information Patent Grant
High performance fluorescence imaging module for genomic testing assay
- Patent number 11,261,489
- Issue date Mar 1, 2022
- ELEMENT BIOSCIENCES, INC.
- Steve Xiangling Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Apparatus and methods for kinetic analysis and determination of nuc...
- Patent number 11,242,560
- Issue date Feb 8, 2022
- Illumina, Inc.
- Michael Previte
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for pairwise sequencing
- Patent number 11,236,388
- Issue date Feb 1, 2022
- ELEMENT BIOSCIENCES, INC.
- Sinan Arslan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for pairwise sequencing
- Patent number 11,220,707
- Issue date Jan 11, 2022
- ELEMENT BIOSCIENCES, INC.
- Sinan Arslan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified polymerases for improved incorporation of nucleotide analo...
- Patent number 11,198,854
- Issue date Dec 14, 2021
- Illumina, Inc.
- Erin Bomati
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Flow cell systems and devices
- Patent number 11,198,121
- Issue date Dec 14, 2021
- ELEMENT BIOSCIENCES, INC.
- Minghao Guo
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
COMPOSITIONS AND METHODS FOR PAIRWISE SEQUENCING
- Publication number 20250236903
- Publication date Jul 24, 2025
- Element Biosciences, Inc.
- Sinan ARSLAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
FLOW CELL DEVICES AND OPTICAL SYSTEMS FOR NUCLEIC ACID SEQUENCING
- Publication number 20250207191
- Publication date Jun 26, 2025
- Element Biosciences, Inc.
- Steve Xiangling Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HIGH PERFORMANCE FLUORESCENCE IMAGING MODULE FOR GENOMIC TESTING ASSAY
- Publication number 20250197925
- Publication date Jun 19, 2025
- Element Biosciences, Inc.
- Steve Xiangling CHEN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PLATFORM FOR DISCOVERY AND ANALYSIS OF THERAPEUTIC AGENTS
- Publication number 20250171929
- Publication date May 29, 2025
- Illumina, Inc.
- Molly He
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
MULTIVALENT BINDING COMPOSITION FOR NUCLEIC ACID ANALYSIS
- Publication number 20250172547
- Publication date May 29, 2025
- Element Biosciences, Inc.
- Michael PREVITE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NUCLEOTIDE TRANSIENT BINDING FOR SEQUENCING METHODS
- Publication number 20250163391
- Publication date May 22, 2025
- Life Technologies Corporation
- Peter VANDER HORN
- G01 - MEASURING TESTING
Information Patent Application
REITERATIVE SHORT READ SEQUENCING INSIDE A CELLULAR SAMPLE
- Publication number 20250146068
- Publication date May 8, 2025
- Element Biosciences, Inc.
- Tsung-Li LIU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OPTICAL SYSTEMS FOR NUCLEIC ACID SEQUENCING AND METHODS THEREOF
- Publication number 20250092455
- Publication date Mar 20, 2025
- Element Biosciences, Inc.
- Arash GHORBANI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MULTIVALENT BINDING COMPOSITIONS WITH REACTIVE GROUPS
- Publication number 20250084478
- Publication date Mar 13, 2025
- Element Biosciences, Inc.
- MICHAEL PREVITE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NUCLEIC ACID HYBRIDIZATION METHODS
- Publication number 20250034628
- Publication date Jan 30, 2025
- Element Biosciences, Inc.
- Sinan ARSLAN
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Application
HIGH PERFORMANCE FLUORESCENCE IMAGING MODULE FOR GENOMIC TESTING ASSAY
- Publication number 20250027144
- Publication date Jan 23, 2025
- Element Biosciences, Inc.
- Sinan ARSLAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR SEQUENCING MULTIPLE REGIONS OF A TEMPL...
- Publication number 20250019760
- Publication date Jan 16, 2025
- Element Biosciences, Inc.
- William LIGHT
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
FLOW CELL DEVICE AND USE THEREOF
- Publication number 20240382956
- Publication date Nov 21, 2024
- Element Biosciences, Inc.
- Minghao GUO
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Application
MULTIVALENT BINDING COMPOSITION FOR NUCLEIC ACID ANALYSIS
- Publication number 20240230631
- Publication date Jul 11, 2024
- Element Biosciences, Inc.
- Sinan Arslan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OPTICAL SYSTEMS FOR NUCLEIC ACID SEQUENCING AND METHODS THEREOF
- Publication number 20240201088
- Publication date Jun 20, 2024
- Element Biosciences, Inc.
- Arash GHORBANI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
OPTICAL SYSTEMS FOR NUCLEIC ACID SEQUENCING AND METHODS THEREOF
- Publication number 20240200133
- Publication date Jun 20, 2024
- Element Biosciences, Inc.
- Arash GHORBANI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR PAIRWISE SEQUENCING
- Publication number 20240191278
- Publication date Jun 13, 2024
- Element Biosciences, Inc.
- Sinan ARSLAN
- G01 - MEASURING TESTING
Information Patent Application
MULTIVALENT BINDING COMPOSITIONS WITH REACTIVE GROUPS
- Publication number 20240117428
- Publication date Apr 11, 2024
- Element Biosciences, Inc.
- MICHAEL PREVITE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SPATIALLY RESOLVED SURFACE CAPTURE OF NUCLEIC ACIDS
- Publication number 20240052398
- Publication date Feb 15, 2024
- Element Biosciences, Inc.
- Michael PREVITE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PLATFORM FOR DISCOVERY AND ANALYSIS OF THERAPEUTIC AGENTS
- Publication number 20240003057
- Publication date Jan 4, 2024
- Illumina, Inc.
- Molly He
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR ASSEMBLING AND READING NUCLEIC ACID SEQUENCES FROM MIXE...
- Publication number 20230392201
- Publication date Dec 7, 2023
- Element Biosciences, Inc.
- James A. STAPLETON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MULTIVALENT BINDING COMPOSITION FOR NUCLEIC ACID ANALYSIS
- Publication number 20230323450
- Publication date Oct 12, 2023
- Element Biosciences, Inc.
- Sinan Arslan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MULTIVALENT BINDING COMPOSITION FOR NUCLEIC ACID ANALYSIS
- Publication number 20230296592
- Publication date Sep 21, 2023
- Element Biosciences, Inc.
- Michael PREVITE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MULTIVALENT BINDING COMPOSITION FOR NUCLEIC ACID ANALYSIS
- Publication number 20230296593
- Publication date Sep 21, 2023
- Element Biosciences, Inc.
- Michael PREVITE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MULTIPLEXED COVID-19 PADLOCK ASSAY
- Publication number 20230295692
- Publication date Sep 21, 2023
- Element Biosciences, Inc.
- Lorenzo BERTI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CONFORMATIONAL PROBES AND METHODS FOR SEQUENCING NUCLEIC ACIDS
- Publication number 20230235395
- Publication date Jul 27, 2023
- Illumina, Inc.
- MOLLY HE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR PAIRED-END SEQUENCING LIBRARY PREPARATION
- Publication number 20230235392
- Publication date Jul 27, 2023
- Element Biosciences, Inc.
- Sinan ARSLAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
POLYMERASES, COMPOSITIONS, AND METHODS OF USE
- Publication number 20230212534
- Publication date Jul 6, 2023
- Illumina, Inc.
- Misha Golynskiy
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR PAIRWISE SEQUENCING
- Publication number 20230203564
- Publication date Jun 29, 2023
- Element Biosciences, Inc.
- Sinan ARSLAN
- G01 - MEASURING TESTING
Information Patent Application
COMPOSITIONS AND METHODS FOR PAIRWISE SEQUENCING
- Publication number 20230193354
- Publication date Jun 22, 2023
- Element Biosciences, Inc.
- Sinan ARSLAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Michael Previte

Person

Patents Grantslast 30 patents

Multipart reagents having increased avidity for polymerase binding

Multivalent binding composition for nucleic acid analysis

Conformational probes and methods for sequencing nucleic acids

Multivalent binding composition for nucleic acid analysis

Nucleotide transient binding for sequencing methods

Optical systems for nucleic acid sequencing and methods thereof

Methods for generating circular nucleic acid molecules

Multivalent binding composition for nucleic acid analysis

Compositions and methods for pairwise sequencing

Compositions and methods for pairwise sequencing

High performance fluorescence imaging module for genomic testing assay

Platform for discovery and analysis of therapeutic agents

Methods and reagents for nucleic acid analysis

Conformational probes and methods for sequencing nucleic acids

Polymerases, compositions, and methods of use

Compositions and methods for pairwise sequencing

High performance fluorescence imaging module for genomic testing assay

Nucleotide transient binding for sequencing methods

Flow cell device and use thereof

Compositions and methods for pairwise sequencing

Tube lens design for improved depth-of-field

High performance fluorescence imaging module for genomic testing assay

Nucleic acid sequencing systems

Multivalent binding composition for nucleic acid analysis

High performance fluorescence imaging module for genomic testing assay

Apparatus and methods for kinetic analysis and determination of nuc...

Compositions and methods for pairwise sequencing

Compositions and methods for pairwise sequencing

Modified polymerases for improved incorporation of nucleotide analo...

Flow cell systems and devices

Patents Applicationslast 30 patents

COMPOSITIONS AND METHODS FOR PAIRWISE SEQUENCING

FLOW CELL DEVICES AND OPTICAL SYSTEMS FOR NUCLEIC ACID SEQUENCING

HIGH PERFORMANCE FLUORESCENCE IMAGING MODULE FOR GENOMIC TESTING ASSAY

PLATFORM FOR DISCOVERY AND ANALYSIS OF THERAPEUTIC AGENTS

MULTIVALENT BINDING COMPOSITION FOR NUCLEIC ACID ANALYSIS

NUCLEOTIDE TRANSIENT BINDING FOR SEQUENCING METHODS

REITERATIVE SHORT READ SEQUENCING INSIDE A CELLULAR SAMPLE

OPTICAL SYSTEMS FOR NUCLEIC ACID SEQUENCING AND METHODS THEREOF

MULTIVALENT BINDING COMPOSITIONS WITH REACTIVE GROUPS

NUCLEIC ACID HYBRIDIZATION METHODS

HIGH PERFORMANCE FLUORESCENCE IMAGING MODULE FOR GENOMIC TESTING ASSAY

COMPOSITIONS AND METHODS FOR SEQUENCING MULTIPLE REGIONS OF A TEMPL...

FLOW CELL DEVICE AND USE THEREOF

MULTIVALENT BINDING COMPOSITION FOR NUCLEIC ACID ANALYSIS

OPTICAL SYSTEMS FOR NUCLEIC ACID SEQUENCING AND METHODS THEREOF

OPTICAL SYSTEMS FOR NUCLEIC ACID SEQUENCING AND METHODS THEREOF

COMPOSITIONS AND METHODS FOR PAIRWISE SEQUENCING

MULTIVALENT BINDING COMPOSITIONS WITH REACTIVE GROUPS

SPATIALLY RESOLVED SURFACE CAPTURE OF NUCLEIC ACIDS

PLATFORM FOR DISCOVERY AND ANALYSIS OF THERAPEUTIC AGENTS

METHODS FOR ASSEMBLING AND READING NUCLEIC ACID SEQUENCES FROM MIXE...

MULTIVALENT BINDING COMPOSITION FOR NUCLEIC ACID ANALYSIS

MULTIVALENT BINDING COMPOSITION FOR NUCLEIC ACID ANALYSIS

MULTIVALENT BINDING COMPOSITION FOR NUCLEIC ACID ANALYSIS

MULTIPLEXED COVID-19 PADLOCK ASSAY

CONFORMATIONAL PROBES AND METHODS FOR SEQUENCING NUCLEIC ACIDS

METHODS FOR PAIRED-END SEQUENCING LIBRARY PREPARATION

POLYMERASES, COMPOSITIONS, AND METHODS OF USE

COMPOSITIONS AND METHODS FOR PAIRWISE SEQUENCING

COMPOSITIONS AND METHODS FOR PAIRWISE SEQUENCING