Michael R. Hale

Person

Bedford, MA, US

People

Patents Grantslast 30 patents

Information Patent Grant
Substituted macrocyclic compounds and related methods of treatment
- Patent number 12,054,495
- Issue date Aug 6, 2024
- Alkermes, Inc.
- Lewis D. Pennington
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Substituted macrocyclic compounds and related methods of treatment
- Patent number 12,006,330
- Issue date Jun 11, 2024
- Alkermes, Inc.
- Lewis D. Pennington
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Pyrrole inhibitors of ERK protein kinase, synthesis thereof and int...
- Patent number RE49500
- Issue date Apr 25, 2023
- Vertex Pharmaceuticals Incorporated
- Gabriel Martinez Botella
Information Patent Grant
Substituted macrocyclic compounds and related methods of treatment
- Patent number 11,542,276
- Issue date Jan 3, 2023
- Alkermes, Inc.
- Lewis D. Pennington
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Pyrrole inhibitors of ERK protein kinase, synthesis thereof and int...
- Patent number RE48266
- Issue date Oct 20, 2020
- Vertex Pharmaceuticals Incorporated
- Gabriel Martinez Botella
Information Patent Grant
Pyrrole inhibitors of erk protein kinase, synthesis thereof and int...
- Patent number RE47318
- Issue date Mar 26, 2019
- Vertex Pharmaceuticals Incorporated
- Gabriel Martinez Botella
Information Patent Grant
Pyrrole inhibitors of ERK protein kinase, synthesis thereof and int...
- Patent number RE46097
- Issue date Aug 9, 2016
- Vertex Pharmaceuticals Incorporated
- Gabriel Martinez Botella
- 001 -
Information Patent Grant
Inhibitors of aspartyl protease
- Patent number 8,455,497
- Issue date Jun 4, 2013
- Vertex Pharmaceuticals Incorporated
- Michael R. Hale
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Inhibitors of aspartyl protease
- Patent number 7,919,523
- Issue date Apr 5, 2011
- Vertex Pharmaceuticals, Inc.
- Michael R. Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Sulphonamide derivatives as prodrugs of aspartyl protease inhibitors
- Patent number 7,592,368
- Issue date Sep 22, 2009
- Vertex Pharmaceuticals Incorporated
- Roger Dennis Tung
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Selective inhibitors of ERK protein kinase and uses thereof
- Patent number 7,501,415
- Issue date Mar 10, 2009
- Vertex Pharmaceuticals Incorporated
- Alexander Aronov
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Pyridine inhibitors of ERK2 and uses thereof
- Patent number 7,462,612
- Issue date Dec 9, 2008
- Vertex Pharmaceuticals Incorporated
- Michael Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compositions useful as protein kinase inhibitors
- Patent number 7,456,190
- Issue date Nov 25, 2008
- Vertex Pharmaceuticals Incorporated
- Francois Maltais
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of aspartyl protease
- Patent number 7,442,718
- Issue date Oct 28, 2008
- Vertex Pharmaceuticals Incorporated
- Michael R Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Sulfonamide inhibitors of aspartyl protease
- Patent number 7,419,967
- Issue date Sep 2, 2008
- Vertex Pharmaceuticals Incorporated
- Michael R Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Heteroaryl compounds useful as inhibitors or protein kinases
- Patent number 7,407,962
- Issue date Aug 5, 2008
- Vertex Pharmaceuticals Incorporated
- Alex Aronov
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Prodrugs of an ERK protein kinase inhibitor
- Patent number 7,358,258
- Issue date Apr 15, 2008
- Vertex Pharmaceuticals Incorporated
- Michael Robin Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Isoxazole compositions useful as inhibitors of ERK
- Patent number 7,354,919
- Issue date Apr 8, 2008
- Vertex Pharmaceuticals Incorporated
- Michael R. Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Pyrrole inhibitors of ERK protein kinase, synthesis thereof and int...
- Patent number 7,354,939
- Issue date Apr 8, 2008
- Vertex Pharmaceuticals Incorporated
- Gabriel Martinez-Botella
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Heterocyclic inhibitors of ERK2 and uses thereof
- Patent number 7,345,054
- Issue date Mar 18, 2008
- Vertex Pharmaceuticals Incorporated
- Michael Robin Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Protein kinase inhibitors and uses thereof
- Patent number 7,304,071
- Issue date Dec 4, 2007
- Vertex Pharmaceuticals Incorporated
- John Cochran
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Heterocyclic inhibitors of ERK2 and uses thereof
- Patent number 7,304,061
- Issue date Dec 4, 2007
- Vertex Pharmaceuticals Incorporated
- Michael Robin Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Pyrazole-derived kinase inhibitors and uses thereof
- Patent number 7,279,476
- Issue date Oct 9, 2007
- Vertex Pharmaceuticals Incorporated
- Oing Tang
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Heterocyclic inhibitors of ERK2 and uses thereof
- Patent number 7,253,187
- Issue date Aug 7, 2007
- Vertex Pharmaceuticals Incorporated
- Jingrong Cao
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Heterocyclic protein kinase inhibitors and uses thereof
- Patent number 7,244,735
- Issue date Jul 17, 2007
- Vertex Pharmaceuticals Inc.
- Judith Straub
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Pyrazole-derived kinase inhibitors and uses thereof
- Patent number 7,183,307
- Issue date Feb 27, 2007
- Vertex Pharmaceuticals Incroporated
- Michael Robin Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of c-Jun N terminal kinases (JNK) and other protein kinases
- Patent number 7,169,798
- Issue date Jan 30, 2007
- Vertex Pharmaceuticals Incorporated
- Jeremy Green
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Pyrazole compositions useful as inhibitors of erk
- Patent number 7,056,944
- Issue date Jun 6, 2006
- Vertex Pharmaceuticals Incorporated
- Michael Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Triazole-derived kinase inhibitors and uses thereof
- Patent number 6,962,936
- Issue date Nov 8, 2005
- Vertex Pharmaceuticals Incorporated
- Michael R. Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Pyrazole compositions useful as inhibitors of ERK
- Patent number 6,949,580
- Issue date Sep 27, 2005
- Vertex Pharmaceuticals Incorporated
- Michael Hale
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
Substituted Macrocyclic Compounds and Related Methods of Treatment
- Publication number 20240368182
- Publication date Nov 7, 2024
- Alkermes, Inc.
- Lewis D. Pennington
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SUBSTITUTED AMIDE MACROCYCLIC COMPOUNDS WITH OREXIN-2 RECEPTOR AGON...
- Publication number 20240124485
- Publication date Apr 18, 2024
- Alkermes, Inc.
- Younggi Choi
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SUBSTITUTED MACROCYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT
- Publication number 20230339969
- Publication date Oct 26, 2023
- Alkermes, Inc.
- Lewis D. Pennington
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PYRROLE INHIBITORS OF ERK PROTEIN KINASE, SYNTHESIS THEREOF AND INT...
- Publication number 20230183276
- Publication date Jun 15, 2023
- VERTEX PHARMACEUTICALS INCORPORATED
- Gabriel Martinez Botella
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Complement Modulators and Related Methods
- Publication number 20230115176
- Publication date Apr 13, 2023
- Ra Pharmaceuticals, Inc.
- Willmen Wing-Menn Youngsaye
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Substituted Macrocyclic Compounds and Related Methods of Treatment
- Publication number 20220194958
- Publication date Jun 23, 2022
- Alkermes, Inc.
- Lewis D. Pennington
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Substituted Macrocyclic Compounds and Related Methods of Treatment
- Publication number 20210155636
- Publication date May 27, 2021
- Alkermes, Inc.
- Lewis D. Pennington
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SULPHONAMIDE DERIVATIVES AS PRODRUGS OF ASPARTYL PROTEASE INHIBITORS
- Publication number 20100124543
- Publication date May 20, 2010
- Vertex Pharmaceuticals Incorporated.
- Roger Dennis Tung
- C07 - ORGANIC CHEMISTRY
Information Patent Application
INHIBITORS OF ASPARTYL PROTEASE
- Publication number 20090274650
- Publication date Nov 5, 2009
- Michael R. Hale
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Inhibitors of aspartyl protease
- Publication number 20090042973
- Publication date Feb 12, 2009
- Michael R. Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Heterocyclic inhibitors of ERK2 and uses thereof
- Publication number 20070265263
- Publication date Nov 15, 2007
- Jingrong Cao
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Sulfonamide inhibitors of aspartyl protease
- Publication number 20060172936
- Publication date Aug 3, 2006
- Michael Robin Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Selective inhibitors of ERK protein kinase and uses thereof
- Publication number 20060160807
- Publication date Jul 20, 2006
- Alexander Aronov
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Inhibitors of ERK protein kinase and uses thereof
- Publication number 20060142572
- Publication date Jun 29, 2006
- Gabriel Martinez-Botella
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Pyrrole inhibitors of ERK protein kinase, synthesis thereof and int...
- Publication number 20060106069
- Publication date May 18, 2006
- Gabriel Martinez-Botella
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Prodrugs of an ERK protein kinase inhibitor
- Publication number 20060058318
- Publication date Mar 16, 2006
- Michael Robin Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Pyridine inhibitors of ERK2 and uses thereof
- Publication number 20060019953
- Publication date Jan 26, 2006
- Michael Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Triazole-derived kinase inhibitors and uses thereof
- Publication number 20050272789
- Publication date Dec 8, 2005
- Michael R. Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Heterocyclic protein kinase inhibitors and uses thereof
- Publication number 20050245499
- Publication date Nov 3, 2005
- Judith Straub
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Heterocyclic inhibitors of ERK2 and uses thereof
- Publication number 20050234059
- Publication date Oct 20, 2005
- Michael Robin Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Pyrazole-derived kinase inhibitors and uses thereof
- Publication number 20050215550
- Publication date Sep 29, 2005
- Oing Tang
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Sulphonamide derivatives as prodrugs of aspartyl protease inhibitors
- Publication number 20050148548
- Publication date Jul 7, 2005
- Vertex Pharmaceuticals Inc.
- Roger Dennis Tung
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Isoxazole compositions useful as inhibitors of ERK
- Publication number 20050090536
- Publication date Apr 28, 2005
- Michael R. Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Inhibitors of c-jun N terminal kinases (JNK) and other protein kinases
- Publication number 20050026967
- Publication date Feb 3, 2005
- Jeremy Green
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Heterocyclic inhibitors of ERK2 and uses thereof
- Publication number 20040229875
- Publication date Nov 18, 2004
- Jingrong Cao
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Compositions useful as protein kinase inhibitors
- Publication number 20040220200
- Publication date Nov 4, 2004
- Francois Maltais
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Heteroaryl compounds useful as inhibitors of protein kinases
- Publication number 20040214928
- Publication date Oct 28, 2004
- Alex Aronov
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Pyrazole-derived kinase inhibitors and uses thereof
- Publication number 20040209935
- Publication date Oct 21, 2004
- Michael Robin Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Inhibitors of aspartyl protease
- Publication number 20040127488
- Publication date Jul 1, 2004
- Vertex Pharmaceuticals Incorporated.
- Michael R. Hale
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Inhibitors of aspartyl protease
- Publication number 20040122000
- Publication date Jun 24, 2004
- Vertex Pharmaceuticals Incorporated.
- Michael R. Hale
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Michael R. Hale

Person

Patents Grantslast 30 patents

Substituted macrocyclic compounds and related methods of treatment

Substituted macrocyclic compounds and related methods of treatment

Pyrrole inhibitors of ERK protein kinase, synthesis thereof and int...

Substituted macrocyclic compounds and related methods of treatment

Pyrrole inhibitors of ERK protein kinase, synthesis thereof and int...

Pyrrole inhibitors of erk protein kinase, synthesis thereof and int...

Pyrrole inhibitors of ERK protein kinase, synthesis thereof and int...

Inhibitors of aspartyl protease

Inhibitors of aspartyl protease

Sulphonamide derivatives as prodrugs of aspartyl protease inhibitors

Selective inhibitors of ERK protein kinase and uses thereof

Pyridine inhibitors of ERK2 and uses thereof

Compositions useful as protein kinase inhibitors

Inhibitors of aspartyl protease

Sulfonamide inhibitors of aspartyl protease

Heteroaryl compounds useful as inhibitors or protein kinases

Prodrugs of an ERK protein kinase inhibitor

Isoxazole compositions useful as inhibitors of ERK

Pyrrole inhibitors of ERK protein kinase, synthesis thereof and int...

Heterocyclic inhibitors of ERK2 and uses thereof

Protein kinase inhibitors and uses thereof

Heterocyclic inhibitors of ERK2 and uses thereof

Pyrazole-derived kinase inhibitors and uses thereof

Heterocyclic inhibitors of ERK2 and uses thereof

Heterocyclic protein kinase inhibitors and uses thereof

Pyrazole-derived kinase inhibitors and uses thereof

Inhibitors of c-Jun N terminal kinases (JNK) and other protein kinases

Pyrazole compositions useful as inhibitors of erk

Triazole-derived kinase inhibitors and uses thereof

Pyrazole compositions useful as inhibitors of ERK

Patents Applicationslast 30 patents

Substituted Macrocyclic Compounds and Related Methods of Treatment

SUBSTITUTED AMIDE MACROCYCLIC COMPOUNDS WITH OREXIN-2 RECEPTOR AGON...

SUBSTITUTED MACROCYCLIC COMPOUNDS AND RELATED METHODS OF TREATMENT

PYRROLE INHIBITORS OF ERK PROTEIN KINASE, SYNTHESIS THEREOF AND INT...

Complement Modulators and Related Methods

Substituted Macrocyclic Compounds and Related Methods of Treatment

Substituted Macrocyclic Compounds and Related Methods of Treatment

SULPHONAMIDE DERIVATIVES AS PRODRUGS OF ASPARTYL PROTEASE INHIBITORS

INHIBITORS OF ASPARTYL PROTEASE

Inhibitors of aspartyl protease

Heterocyclic inhibitors of ERK2 and uses thereof

Sulfonamide inhibitors of aspartyl protease

Selective inhibitors of ERK protein kinase and uses thereof

Inhibitors of ERK protein kinase and uses thereof

Pyrrole inhibitors of ERK protein kinase, synthesis thereof and int...

Prodrugs of an ERK protein kinase inhibitor

Pyridine inhibitors of ERK2 and uses thereof

Triazole-derived kinase inhibitors and uses thereof

Heterocyclic protein kinase inhibitors and uses thereof

Heterocyclic inhibitors of ERK2 and uses thereof

Pyrazole-derived kinase inhibitors and uses thereof

Sulphonamide derivatives as prodrugs of aspartyl protease inhibitors

Isoxazole compositions useful as inhibitors of ERK

Inhibitors of c-jun N terminal kinases (JNK) and other protein kinases

Heterocyclic inhibitors of ERK2 and uses thereof

Compositions useful as protein kinase inhibitors

Heteroaryl compounds useful as inhibitors of protein kinases

Pyrazole-derived kinase inhibitors and uses thereof

Inhibitors of aspartyl protease

Inhibitors of aspartyl protease