Michelle Machacek

Person

Brookline, MA, US

People

Patents Grantslast 30 patents

Information Patent Grant
PRMT5 inhibitors
- Patent number 11,981,701
- Issue date May 14, 2024
- Merck Sharp & Dohme LLC
- Jongwon Lim
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
PRMT5 inhibitors
- Patent number 11,098,059
- Issue date Aug 24, 2021
- Merck Sharp & Dohme Corp.
- Michelle R. Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
PRMT5 inhibitors
- Patent number 10,947,234
- Issue date Mar 16, 2021
- Merck Sharp & Dohme Corp.
- Michelle R. Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Tricyclic compounds as inhibitors of mutant IDH enzymes
- Patent number 10,508,108
- Issue date Dec 17, 2019
- Merck Sharp & Dohme Corp.
- Christian Fischer
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Tricyclic compounds as inhibitors of mutant IDH enzymes
- Patent number 10,442,819
- Issue date Oct 15, 2019
- Merck Sharp & Dohme Corp.
- Christian Fischer
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Tricyclic compounds as inhibitors of mutant IDH enzymes
- Patent number 10,086,000
- Issue date Oct 2, 2018
- Merck Sharp & Dohme Corp.
- Christian Fischer
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inh...
- Patent number 9,783,531
- Issue date Oct 10, 2017
- Merck Sharp & Dohme Corp.
- Michelle R. Machacek
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inh...
- Patent number 9,745,295
- Issue date Aug 29, 2017
- Merck Sharp & Dohme Corp.
- Neville J. Anthony
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
2,6,7 substituted purines as HDM2 inhibitors
- Patent number 9,682,978
- Issue date Jun 20, 2017
- Merck Sharp & Dohme Corp.
- Matthew P. Christopher
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Substituted pyrrolopyrimidines as HDM2 inhibitors
- Patent number 9,637,493
- Issue date May 2, 2017
- Merck Sharp & Dohme Corp.
- Christopher Dinsmore
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Amino-pyrimidine-containing spleen tyrosine kinase (Syk) inhibitors
- Patent number 9,624,210
- Issue date Apr 18, 2017
- Merck Sharp & Dohme Corp.
- Michelle R. Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Triazolyl derivatives as Syk inhibitors
- Patent number 9,586,931
- Issue date Mar 7, 2017
- Merck Sharp & Dohme Corp.
- Michelle R. Machacek
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
2,6,7,8 substituted purines as HDM2 inhibitors
- Patent number 9,540,377
- Issue date Jan 10, 2017
- Merck Sharp & Dohme Corp.
- Carolyn Michele Cammarano
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Pyrazolyl derivatives as Syk inhibitors
- Patent number 9,242,984
- Issue date Jan 26, 2016
- Merck Sharp & Dohme Corp.
- Michelle R. Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Substituted imidazopyridines as HDM2 inhibitors
- Patent number 8,962,611
- Issue date Feb 24, 2015
- Merck Sharp & Dohme Corp.
- Matthew P. Christopher
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Substituted imidazopyridines as HDM2 inhibitors
- Patent number 8,846,657
- Issue date Sep 30, 2014
- Merck Sharp & Dohme Corp.
- Matthew P. Christopher
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Amino-pyridine-containing spleen tyrosine kinase (SYK) inhibitors
- Patent number 8,796,310
- Issue date Aug 5, 2014
- Merck Sharp & Dohme Corp.
- Eric Thomas Romeo
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Aminopyrimidines as SYK inhibitors
- Patent number 8,759,366
- Issue date Jun 24, 2014
- Merck Sharp & Dohme Corp.
- Kaleen Konrad Childers
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Aminopyrimidines as Syk inhibitors
- Patent number 8,735,417
- Issue date May 27, 2014
- Merck Sharp & Dohme Corp.
- Michael D. Altman
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Quinolinone PDE2 inhibitors
- Patent number 8,680,116
- Issue date Mar 25, 2014
- Merck Sharp & Dohme Corp.
- Pablo DeLeon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Aminopyrimidines as SYK inhibitors
- Patent number 8,551,984
- Issue date Oct 8, 2013
- Merck Sharp & Dohme Corp.
- Michael D. Altman
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of janus kinases
- Patent number 8,431,569
- Issue date Apr 30, 2013
- Merck Sharp & Dohme Corp.
- Jonathan R. Young
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of janus kinases
- Patent number 8,420,695
- Issue date Apr 16, 2013
- Merck Sharp & Dohme Corp.
- Kevin Wilson
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of janus kinases
- Patent number 8,367,706
- Issue date Feb 5, 2013
- Merck Sharp & Dohme Corp.
- Michael Altman
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of Janus kinases
- Patent number 8,344,144
- Issue date Jan 1, 2013
- Merck Sharp & Dohme Corp.
- Michelle Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of Janus kinases
- Patent number 8,278,335
- Issue date Oct 2, 2012
- Merck Sharp & Dohme Corp.
- Michelle R. Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of janus kinases
- Patent number 7,763,634
- Issue date Jul 27, 2010
- Merck & Co., Inc.
- Jonathan R. Young
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Tyrosine kinase inhibitors
- Patent number 7,550,478
- Issue date Jun 23, 2009
- Merck & Co. Inc.
- Christopher J. Dinsmore
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
PRMT5 INHIBITORS
- Publication number 20230114091
- Publication date Apr 13, 2023
- Merck Sharp & Dohme LLC
- Michelle Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PRMT5 INHIBITORS
- Publication number 20230108114
- Publication date Apr 6, 2023
- Merck Sharp & Dohme LLC
- Michelle Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PRMT5 INHIBITORS
- Publication number 20230108452
- Publication date Apr 6, 2023
- Merck Sharp & Dohme LLC
- Michelle Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PRMT5 INHIBITORS
- Publication number 20230092404
- Publication date Mar 23, 2023
- Merck Sharp & Dohme LLC
- Michelle Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PRMT5 INHIBITORS
- Publication number 20220363707
- Publication date Nov 17, 2022
- MERCK SHARP & DOHME CORP.
- Michelle Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PRMT5 INHIBITORS
- Publication number 20210309688
- Publication date Oct 7, 2021
- MERCK SHARP & DOHME CORP.
- Jongwon Lim
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PRMT5 INHIBITORS
- Publication number 20210309687
- Publication date Oct 7, 2021
- MERCK SHARP & DOHME CORP.
- Michelle Machacek
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
PRMT5 INHIBITORS
- Publication number 20210277009
- Publication date Sep 9, 2021
- MERCK SHARP & DOHME CORP.
- David Witter
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PRMT5 INHIBITORS
- Publication number 20200361931
- Publication date Nov 19, 2020
- MERCK SHARP & DOHME CORP.
- Michelle R. Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PRMT5 INHIBITORS
- Publication number 20200354377
- Publication date Nov 12, 2020
- MERCK SHARP & DOHME CORP.
- Michelle R. Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NOVEL TRICYCLIC COMPOUNDS AS INHIBITORS OF MUTANT IDH ENZYMES
- Publication number 20170369507
- Publication date Dec 28, 2017
- MERCK SHARP & DOHME CORP.
- Fischer Christian
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
NOVEL TRICYCLIC COMPOUNDS AS INHIBITORS OF MUTANT IDH ENZYMES
- Publication number 20170362220
- Publication date Dec 21, 2017
- MERCK SHARP & DOHME CORP.
- Christian Fischer
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NOVEL TRICYCLIC COMPOUNDS AS INHIBITORS OF MUTANT IDH ENZYMES
- Publication number 20170360800
- Publication date Dec 21, 2017
- MERCK SHARP & DOHME CORP.
- Christian Fischer
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INH...
- Publication number 20160311813
- Publication date Oct 27, 2016
- MERCK SHARP & DOHME CORP.
- Michelle R. Machacek
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INH...
- Publication number 20160060255
- Publication date Mar 3, 2016
- Merck Canada Inc.
- Neville J. Anthony
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
2,6,7 SUBSTITUTED PURINES AS HDM2 INHIBITORS
- Publication number 20150368247
- Publication date Dec 24, 2015
- MERCK SHARP & DOHME CORP.
- Matthew P. Christopher
- C07 - ORGANIC CHEMISTRY
Information Patent Application
2,6,7,8 SUBSTITUTED PURINES AS HDM2 INHIBITORS
- Publication number 20150353553
- Publication date Dec 10, 2015
- MERCK SHARP & DOHME CORP.
- Carolyn Michele Cammarano
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SUBSTITUTED PYRROLOPYRIMIDINES AS HDM2 INHIBITORS
- Publication number 20150329548
- Publication date Nov 19, 2015
- MERCK SHARP & DOHME CORP.
- Christopher Dinsmore
- C07 - ORGANIC CHEMISTRY
Information Patent Application
AMINO-PYRIMIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS
- Publication number 20150329531
- Publication date Nov 19, 2015
- MERCK SHARP & DOHME CORP.
- Michelle R. Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TRIAZOLYL DERIVATIVES AS SYK INHIBITORS
- Publication number 20150239866
- Publication date Aug 27, 2015
- Merck Canada Inc.
- Michelle R. Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PYRAZOLYL DERIVATIVES AS SYK INHIBITORS
- Publication number 20150191461
- Publication date Jul 9, 2015
- MERCK SHARP & DOHME CORP.
- Michelle R. Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SUBSTITUTED IMIDAZOPYRIDINES AS HDM2 INHIBITORS
- Publication number 20140357618
- Publication date Dec 4, 2014
- Matthew P. Christopher
- C07 - ORGANIC CHEMISTRY
Information Patent Application
AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS
- Publication number 20140323440
- Publication date Oct 30, 2014
- Eric Thomas Miller
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Aminopyrimidines as SYK Inhibitors
- Publication number 20140243290
- Publication date Aug 28, 2014
- Michael D. Altman
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Substituted Imidazopyridines as HDM2 Inhibitors
- Publication number 20140179680
- Publication date Jun 26, 2014
- Matthew P. Christopher
- C07 - ORGANIC CHEMISTRY
Information Patent Application
IMIDOTHIAZOLE KINASE INHIBITORS
- Publication number 20130225591
- Publication date Aug 29, 2013
- Michelle R. Machacek
- C07 - ORGANIC CHEMISTRY
Information Patent Application
AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS
- Publication number 20130090309
- Publication date Apr 11, 2013
- Eric Thomas Romeo
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
AMINOPYRIMIDINES AS SYK INHIBITORS
- Publication number 20120309735
- Publication date Dec 6, 2012
- Michael D. Altman
- C07 - ORGANIC CHEMISTRY
Information Patent Application
AMINOPYRIMIDINES AS SYK INHIBITORS
- Publication number 20120277192
- Publication date Nov 1, 2012
- Michael D. Altman
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Quinolinone PDE2 Inhibitors
- Publication number 20120115885
- Publication date May 10, 2012
- Pablo De Leon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Michelle Machacek

Person

Patents Grantslast 30 patents

PRMT5 inhibitors

PRMT5 inhibitors

PRMT5 inhibitors

Tricyclic compounds as inhibitors of mutant IDH enzymes

Tricyclic compounds as inhibitors of mutant IDH enzymes

Tricyclic compounds as inhibitors of mutant IDH enzymes

Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inh...

Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inh...

2,6,7 substituted purines as HDM2 inhibitors

Substituted pyrrolopyrimidines as HDM2 inhibitors

Amino-pyrimidine-containing spleen tyrosine kinase (Syk) inhibitors

Triazolyl derivatives as Syk inhibitors

2,6,7,8 substituted purines as HDM2 inhibitors

Pyrazolyl derivatives as Syk inhibitors

Substituted imidazopyridines as HDM2 inhibitors

Substituted imidazopyridines as HDM2 inhibitors

Amino-pyridine-containing spleen tyrosine kinase (SYK) inhibitors

Aminopyrimidines as SYK inhibitors

Aminopyrimidines as Syk inhibitors

Quinolinone PDE2 inhibitors

Aminopyrimidines as SYK inhibitors

Inhibitors of janus kinases

Inhibitors of janus kinases

Inhibitors of janus kinases

Inhibitors of Janus kinases

Inhibitors of Janus kinases

Inhibitors of janus kinases

Tyrosine kinase inhibitors

Patents Applicationslast 30 patents

PRMT5 INHIBITORS

PRMT5 INHIBITORS

PRMT5 INHIBITORS

PRMT5 INHIBITORS

PRMT5 INHIBITORS

PRMT5 INHIBITORS

PRMT5 INHIBITORS

PRMT5 INHIBITORS

PRMT5 INHIBITORS

PRMT5 INHIBITORS

NOVEL TRICYCLIC COMPOUNDS AS INHIBITORS OF MUTANT IDH ENZYMES

NOVEL TRICYCLIC COMPOUNDS AS INHIBITORS OF MUTANT IDH ENZYMES

NOVEL TRICYCLIC COMPOUNDS AS INHIBITORS OF MUTANT IDH ENZYMES

THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INH...

THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INH...

2,6,7 SUBSTITUTED PURINES AS HDM2 INHIBITORS

2,6,7,8 SUBSTITUTED PURINES AS HDM2 INHIBITORS

SUBSTITUTED PYRROLOPYRIMIDINES AS HDM2 INHIBITORS

AMINO-PYRIMIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS

TRIAZOLYL DERIVATIVES AS SYK INHIBITORS

PYRAZOLYL DERIVATIVES AS SYK INHIBITORS

SUBSTITUTED IMIDAZOPYRIDINES AS HDM2 INHIBITORS

AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS

Aminopyrimidines as SYK Inhibitors

Substituted Imidazopyridines as HDM2 Inhibitors

IMIDOTHIAZOLE KINASE INHIBITORS

AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS

AMINOPYRIMIDINES AS SYK INHIBITORS

AMINOPYRIMIDINES AS SYK INHIBITORS

Quinolinone PDE2 Inhibitors