Mihalis Kariolis

Person

Stanford, CA, US

People

Patents Grantslast 30 patents

Information Patent Grant
Methods of engineering transferrin receptor binding polypeptides
- Patent number 11,912,778
- Issue date Feb 27, 2024
- Denali Therapeutics Inc.
- Xiaocheng Chen
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Fusion proteins comprising sulfoglucosamine sulfohydrolase enzymes...
- Patent number 11,884,944
- Issue date Jan 30, 2024
- Denali Therapeutics Inc.
- Tina Giese
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Fusion proteins comprising enzyme replacement therapy enzymes
- Patent number 11,866,742
- Issue date Jan 9, 2024
- Denali Therapeutics Inc.
- Anastasia Henry
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered transferrin receptor binding polypeptides
- Patent number 11,795,232
- Issue date Oct 24, 2023
- Denali Therapeutics Inc.
- Xiaocheng Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Engineered polypeptides
- Patent number 11,732,023
- Issue date Aug 22, 2023
- Denali Therapeutics Inc.
- Xiaocheng Chen
- G01 - MEASURING TESTING
Information Patent Grant
Fusion proteins comprising an engineered knottin peptide and uses t...
- Patent number 11,498,952
- Issue date Nov 15, 2022
- The Board of Trustees of the Leland Stanford Junior University
- Jennifer R. Cochran
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
SPD-1 variant# FC fusion proteins
- Patent number 11,498,955
- Issue date Nov 15, 2022
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Receptor-based antagonists of the programmed cell death 1 (PD-1) pa...
- Patent number 11,400,133
- Issue date Aug 2, 2022
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Modified AXL peptides and their use in inhibition of AXL signaling...
- Patent number 11,136,563
- Issue date Oct 5, 2021
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-TREM2 antibodies and methods of use thereof
- Patent number 11,124,567
- Issue date Sep 21, 2021
- Denali Therapeutics Inc.
- Mark S. Dennis
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antifibrotic activity of GAS6 inhibitor
- Patent number 10,876,176
- Issue date Dec 29, 2020
- Aravive Biologics, Inc.
- Raymond Tabibiazar
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Fusion proteins comprising enzyme replacement therapy enzymes
- Patent number 10,870,837
- Issue date Dec 22, 2020
- Denali Therapeutics Inc.
- Anastasia Henry
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Fusion proteins comprising an engineered knottin peptide and uses t...
- Patent number 10,844,106
- Issue date Nov 24, 2020
- The Board of Trustees of the Leland Stanford Junior University
- Jennifer R. Cochran
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Receptor-based antagonists of the programmed cell death 1 (PD-1) pa...
- Patent number 10,588,938
- Issue date Mar 17, 2020
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Engineered polypeptides
- Patent number 10,457,717
- Issue date Oct 29, 2019
- Denali Therapeutics Inc.
- Xiaocheng Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibition of AXL/GAS6 signaling in the treatment of liver fibrosis
- Patent number 9,879,061
- Issue date Jan 30, 2018
- The Board of Trustees of the Leland Stanford Junior University
- Patrick O'Connor
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified AXL peptides and their use in inhibition of AXL signaling...
- Patent number 9,822,347
- Issue date Nov 21, 2017
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Inhibition of AXL signaling in anti-metastatic therapy
- Patent number 9,266,947
- Issue date Feb 23, 2016
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Inhibition of AXL signaling in anti-metastatic therapy
- Patent number 9,074,192
- Issue date Jul 7, 2015
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Cystine knot peptides binding to alpha IIb beta 3 integrins and met...
- Patent number 8,778,888
- Issue date Jul 15, 2014
- The Board of Trustees of the Leland Stanford Junior University
- Jennifer R. Cochran
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Inhibition of AXL signaling in anti-metastatic therapy
- Patent number 8,618,254
- Issue date Dec 31, 2013
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES
- Publication number 20240271326
- Publication date Aug 15, 2024
- Denali Therapeutics Inc.
- Xiaocheng Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES
- Publication number 20240271327
- Publication date Aug 15, 2024
- Denali Therapeutics Inc.
- Xiaocheng Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTI-TRANSFERRIN RECEPTOR FUSION PROTEINS AND METHODS OF USE THEREOF
- Publication number 20240148866
- Publication date May 9, 2024
- Denali Therapeutics Inc.
- Annie ARGUELLO
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
FUSION PROTEINS COMPRISING SULFOGLUCOSAMINE SULFOHYDROLASE ENZYMES...
- Publication number 20240150736
- Publication date May 9, 2024
- Denali Therapeutics Inc.
- Tina GIESE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES
- Publication number 20240141058
- Publication date May 2, 2024
- Denali Therapeutics Inc.
- Xiaocheng Chen
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
ENGINEERED TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES
- Publication number 20240024432
- Publication date Jan 25, 2024
- Denali Therapeutics Inc.
- Xiaocheng Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ENGINEERED TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES
- Publication number 20240018253
- Publication date Jan 18, 2024
- Denali Therapeutics Inc.
- Xiaocheng Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
AFFINITY-BASED METHODS FOR USING TRANSFERRIN RECEPTOR-BINDING PROTEINS
- Publication number 20230381286
- Publication date Nov 30, 2023
- Denali Therapeutics Inc.
- Mark S. Dennis
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES
- Publication number 20230235072
- Publication date Jul 27, 2023
- Denali Therapeutics Inc.
- Xiaocheng Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Fusion Proteins Comprising an Engineered Knottin Peptide and Uses T...
- Publication number 20230227523
- Publication date Jul 20, 2023
- The Board of Trustees of the Leland Stanford Junior University
- Jennifer R. Cochran
- C07 - ORGANIC CHEMISTRY
Information Patent Application
sPD-1 VARIANT – FC FUSION PROTEINS
- Publication number 20230131056
- Publication date Apr 27, 2023
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
FUSION PROTEINS COMPRISING SULFOGLUCOSAMINE SULFOHYDROLASE ENZYMES...
- Publication number 20230062800
- Publication date Mar 2, 2023
- Denali Therapeutics Inc.
- Tina GIESE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECEPTOR-BASED ANTAGONISTS OF THE PROGRAMMED CELL DEATH 1 (PD-1) PA...
- Publication number 20220378873
- Publication date Dec 1, 2022
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Modified AXL Peptides and Their Use in Inhibition of AXL Signaling...
- Publication number 20220220458
- Publication date Jul 14, 2022
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
FORMULATIONS OF PROTEIN MOLECULES COMPRISING IDURONATE 2-SULFATASE
- Publication number 20220184186
- Publication date Jun 16, 2022
- Denali Therapeutics Inc.
- Dana ANDERSEN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF
- Publication number 20220177576
- Publication date Jun 9, 2022
- Mark S. Dennis
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF
- Publication number 20210214438
- Publication date Jul 15, 2021
- Denali Therapeutics Inc.
- Mark S. Dennis
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Fusion Proteins Comprising an Engineered Knottin Peptide and Uses T...
- Publication number 20210206824
- Publication date Jul 8, 2021
- The Board of Trustees of the Leland Stanford Junior University
- Jennifer R. Cochran
- C07 - ORGANIC CHEMISTRY
Information Patent Application
FUSION PROTEINS COMPRISING ENZYME REPLACEMENT THERAPY ENZYMES
- Publication number 20210198640
- Publication date Jul 1, 2021
- Denali Therapeutics Inc.
- Giuseppe ASTARITA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TRANSFERRIN RECEPTOR-BINDING POLYPEPTIDES AND USES THEREOF
- Publication number 20210130485
- Publication date May 6, 2021
- Denali Therapeutics Inc.
- Mark S. Dennis
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ENGINEERED TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES
- Publication number 20200369746
- Publication date Nov 26, 2020
- Denali Therapeutics Inc.
- Xiaocheng Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
RECEPTOR-BASED ANTAGONISTS OF THE PROGRAMMED CELL DEATH 1 (PD-1) PA...
- Publication number 20200360474
- Publication date Nov 19, 2020
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ALBUMIN VARIANTS FOR ENHANCED SERUM HALF-LIFE
- Publication number 20200317749
- Publication date Oct 8, 2020
- Denali Therapeutics Inc.
- Mark S. Dennis
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
AFFINITY-BASED METHODS FOR USING TRANSFERRIN RECEPTOR-BINDING PROTEINS
- Publication number 20200289627
- Publication date Sep 17, 2020
- Denali Therapeutics Inc.
- Mark S. Dennis
- C07 - ORGANIC CHEMISTRY
Information Patent Application
FUSION PROTEINS COMPRISING ENZYME REPLACEMENT THERAPY ENZYMES
- Publication number 20200277584
- Publication date Sep 3, 2020
- Denali Therapeutics Inc.
- Giuseppe ASTARITA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ENGINEERED POLYPEPTIDES
- Publication number 20200262890
- Publication date Aug 20, 2020
- Denali Therapeutics Inc.
- Xiaocheng Chen
- G01 - MEASURING TESTING
Information Patent Application
ENGINEERED TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES
- Publication number 20200223935
- Publication date Jul 16, 2020
- Denali Therapeutics Inc.
- Xiaocheng Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
sPD-1 VARIANT - FC FUSION PROTEINS
- Publication number 20200181231
- Publication date Jun 11, 2020
- The Board of Trustees of the Leland Stanford Junior University
- Amato J. Giaccia
- C07 - ORGANIC CHEMISTRY
Information Patent Application
FUSION PROTEINS COMPRISING ENZYME REPLACEMENT THERAPY ENZYMES
- Publication number 20190249155
- Publication date Aug 15, 2019
- Denali Therapeutics Inc.
- Anastasia Henry
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ENGINEERED POLYPEPTIDES
- Publication number 20180237496
- Publication date Aug 23, 2018
- Denali Therapeutics Inc.
- Xiaocheng Chen
- C07 - ORGANIC CHEMISTRY

Mihalis Kariolis

Person

Patents Grantslast 30 patents

Methods of engineering transferrin receptor binding polypeptides

Fusion proteins comprising sulfoglucosamine sulfohydrolase enzymes...

Fusion proteins comprising enzyme replacement therapy enzymes

Engineered transferrin receptor binding polypeptides

Engineered polypeptides

Fusion proteins comprising an engineered knottin peptide and uses t...

SPD-1 variant# FC fusion proteins

Receptor-based antagonists of the programmed cell death 1 (PD-1) pa...

Modified AXL peptides and their use in inhibition of AXL signaling...

Anti-TREM2 antibodies and methods of use thereof

Antifibrotic activity of GAS6 inhibitor

Fusion proteins comprising enzyme replacement therapy enzymes

Fusion proteins comprising an engineered knottin peptide and uses t...

Receptor-based antagonists of the programmed cell death 1 (PD-1) pa...

Engineered polypeptides

Inhibition of AXL/GAS6 signaling in the treatment of liver fibrosis

Modified AXL peptides and their use in inhibition of AXL signaling...

Inhibition of AXL signaling in anti-metastatic therapy

Inhibition of AXL signaling in anti-metastatic therapy

Cystine knot peptides binding to alpha IIb beta 3 integrins and met...

Inhibition of AXL signaling in anti-metastatic therapy

Patents Applicationslast 30 patents

METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES

METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES

ANTI-TRANSFERRIN RECEPTOR FUSION PROTEINS AND METHODS OF USE THEREOF

FUSION PROTEINS COMPRISING SULFOGLUCOSAMINE SULFOHYDROLASE ENZYMES...

METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES

ENGINEERED TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES

ENGINEERED TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES

AFFINITY-BASED METHODS FOR USING TRANSFERRIN RECEPTOR-BINDING PROTEINS

METHODS OF ENGINEERING TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES

Fusion Proteins Comprising an Engineered Knottin Peptide and Uses T...

sPD-1 VARIANT – FC FUSION PROTEINS

FUSION PROTEINS COMPRISING SULFOGLUCOSAMINE SULFOHYDROLASE ENZYMES...

RECEPTOR-BASED ANTAGONISTS OF THE PROGRAMMED CELL DEATH 1 (PD-1) PA...

Modified AXL Peptides and Their Use in Inhibition of AXL Signaling...

FORMULATIONS OF PROTEIN MOLECULES COMPRISING IDURONATE 2-SULFATASE

ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF

ANTI-TREM2 ANTIBODIES AND METHODS OF USE THEREOF

Fusion Proteins Comprising an Engineered Knottin Peptide and Uses T...

FUSION PROTEINS COMPRISING ENZYME REPLACEMENT THERAPY ENZYMES

TRANSFERRIN RECEPTOR-BINDING POLYPEPTIDES AND USES THEREOF

ENGINEERED TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES

RECEPTOR-BASED ANTAGONISTS OF THE PROGRAMMED CELL DEATH 1 (PD-1) PA...

ALBUMIN VARIANTS FOR ENHANCED SERUM HALF-LIFE

AFFINITY-BASED METHODS FOR USING TRANSFERRIN RECEPTOR-BINDING PROTEINS

FUSION PROTEINS COMPRISING ENZYME REPLACEMENT THERAPY ENZYMES

ENGINEERED POLYPEPTIDES

ENGINEERED TRANSFERRIN RECEPTOR BINDING POLYPEPTIDES

sPD-1 VARIANT - FC FUSION PROTEINS

FUSION PROTEINS COMPRISING ENZYME REPLACEMENT THERAPY ENZYMES

ENGINEERED POLYPEPTIDES