Muthiah Manoharan

Person

Cambridge, MA, US

People

Patents Grantslast 30 patents

Information Patent Grant
SERPINA1 iRNA compositions and methods of use thereof
- Patent number 12,071,619
- Issue date Aug 27, 2024
- Alnylam Pharmaceuticals, Inc.
- Alfica Sehgal
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Carbohydrate conjugates as delivery agents for oligonucleotides
- Patent number 12,059,468
- Issue date Aug 13, 2024
- Alnylam Pharmaceuticals, Inc.
- Muthiah Manoharan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Lipids and compositions for the delivery of therapeutics
- Patent number 12,042,541
- Issue date Jul 23, 2024
- ARBUTUS BIOPHARMA CORPORATION
- Muthiah Manoharan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Lipid compositions
- Patent number 12,023,383
- Issue date Jul 2, 2024
- ARBUTUS BIOPHARMA CORPORATION
- Muthiah Manoharan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Extrahepatic delivery
- Patent number 12,005,074
- Issue date Jun 11, 2024
- Alnylam Pharmaceuticals, Inc.
- Jayaprakash K. Nair
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Carbohydrate conjugate RNA agents and process for their preparation
- Patent number 11,944,687
- Issue date Apr 2, 2024
- Alnylam Pharmaceuticals, Inc.
- Jayaprakash K. Nair
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Complement component C5 iRNA compositions and methods of use thereof
- Patent number 11,873,491
- Issue date Jan 16, 2024
- Alnylam Pharmaceuticals, Inc.
- Kevin Fitzgerald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Serpina1 iRNA compositions and methods of use thereof
- Patent number 11,725,207
- Issue date Aug 15, 2023
- Alnylam Pharmaceuticals, Inc.
- Mark K. Schlegel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Biodegradable lipids for the delivery of active agents
- Patent number 11,679,158
- Issue date Jun 20, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Carbohydrate conjugates as delivery agents for oligonucleotides
- Patent number 11,666,653
- Issue date Jun 6, 2023
- Alnylam Pharmaceuticals, Inc.
- Muthiah Manoharan
- Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMA...
Information Patent Grant
Biodegradable lipids for the delivery of active agents
- Patent number 11,633,479
- Issue date Apr 25, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Biodegradable lipids for the delivery of active agents
- Patent number 11,633,480
- Issue date Apr 25, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Biodegradable lipids for the delivery of active agents
- Patent number 11,612,657
- Issue date Mar 28, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Chirally-enriched double-stranded RNA agents
- Patent number 11,597,932
- Issue date Mar 7, 2023
- Alnylam Pharmaceuticals, Inc.
- Muthiah Manoharan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Biodegradable lipids for the delivery of active agents
- Patent number 11,590,229
- Issue date Feb 28, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified double-stranded RNA agents
- Patent number 11,549,109
- Issue date Jan 10, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Therapeutic compositions
- Patent number 11,530,408
- Issue date Dec 20, 2022
- Alnylam Pharmaceuticals, Inc.
- Muthiah Manoharan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified RNA agents with reduced off-target effect
- Patent number 11,504,391
- Issue date Nov 22, 2022
- Alnylam Pharmaceuticals, Inc.
- Mark K. Schlegel
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified double-stranded RNA agents
- Patent number 11,427,822
- Issue date Aug 30, 2022
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Lipid containing formulations
- Patent number 11,420,931
- Issue date Aug 23, 2022
- ARBUTUS BIOPHARMA CORPORATION
- Muthiah Manoharan
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof
- Patent number 11,408,001
- Issue date Aug 9, 2022
- Alnylam Pharmaceuticals, Inc.
- Kevin Fitzgerald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified RNAi agents
- Patent number 11,406,716
- Issue date Aug 9, 2022
- Alnylam Pharmaceuticals, Inc.
- Kallanthottathil G. Rajeev
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Modified double-stranded RNA agents
- Patent number 11,401,517
- Issue date Aug 2, 2022
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Biodegradable lipids for the delivery of active agents
- Patent number 11,400,158
- Issue date Aug 2, 2022
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Biodegradable lipids for the delivery of active agents
- Patent number 11,382,979
- Issue date Jul 12, 2022
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Modified iRNA agents
- Patent number 11,312,957
- Issue date Apr 26, 2022
- Alnylam Pharmaceuticals, Inc.
- Muthiah Manoharan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Biodegradable lipids for the delivery of active agents
- Patent number 11,246,933
- Issue date Feb 15, 2022
- Alnylam Pharmaceuticals, Inc.
- Martin Maier
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
High density lipoprotein binding protein (Hdlbp/Vigilin) iRNA compo...
- Patent number 11,207,342
- Issue date Dec 28, 2021
- Alnylam Pharmaceuticals, Inc.
- Muthiah Manoharan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Complement component C5 iRNA compositions and methods of use thereof
- Patent number 11,162,098
- Issue date Nov 2, 2021
- Alnylam Pharmaceuticals, Inc.
- Kevin Fitzgerald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof
- Patent number 11,142,766
- Issue date Oct 12, 2021
- Alnylam Pharmaceuticals, Inc.
- Kevin Fitzgerald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
EXTRAHEPATIC DELIVERY
- Publication number 20240358738
- Publication date Oct 31, 2024
- Alnylam Pharmaceuticals, Inc.
- Jayaprakash K. NAIR
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
- Publication number 20240285767
- Publication date Aug 29, 2024
- Alnylam Pharmaceuticals, Inc.
- Martin MAIER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
- Publication number 20240285768
- Publication date Aug 29, 2024
- Martin MAIER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
RNAi AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING T...
- Publication number 20240279652
- Publication date Aug 22, 2024
- Alnylam Pharmaceuticals, Inc.
- Kallanthottathil G. Rajeev
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
- Publication number 20240269289
- Publication date Aug 15, 2024
- Alnylam Pharmaceuticals, Inc.
- Martin MAIER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
- Publication number 20240271136
- Publication date Aug 15, 2024
- Alnylam Pharmaceuticals, Inc.
- Kevin Fitzgerald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CARBOHYDRATE CONJUGATED RNA AGENTS AND PROCESS FOR THEIR PREPARATION
- Publication number 20240252653
- Publication date Aug 1, 2024
- Jayaprakash K. NAIR
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
- Publication number 20240245778
- Publication date Jul 25, 2024
- Martin MAIER
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FO...
- Publication number 20240200061
- Publication date Jun 20, 2024
- Alnylam Pharmaceuticals, Inc.
- Jayaprakash K. Nair
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED OLIGONUCLEOTIDES
- Publication number 20240116973
- Publication date Apr 11, 2024
- Alnylam Pharmaceuticals, Inc.
- Muthiah MANOHARAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR INHIBITION OF EXPRESSION OF APOLIPOPRO...
- Publication number 20240110180
- Publication date Apr 4, 2024
- Alnylam Pharmaceuticals, Inc.
- Brian Bettencourt
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LIPID COMPOSITIONS
- Publication number 20240066129
- Publication date Feb 29, 2024
- ARBUTUS BIOPHARMA CORPORATION
- Muthiah Manoharan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS
- Publication number 20240042039
- Publication date Feb 8, 2024
- ARBUTUS BIOPHARMA CORPORATION
- Muthiah Manoharan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
EXTRAHEPATIC DELIVERY
- Publication number 20240009225
- Publication date Jan 11, 2024
- Alnylam Pharmaceuticals, Inc.
- Jayaprakash K. NAIR
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS
- Publication number 20230381319
- Publication date Nov 30, 2023
- ARBUTUS BIOPHARMA CORPORATION
- Muthiah Manoharan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
- Publication number 20230365965
- Publication date Nov 16, 2023
- Genzyme Corporation
- Akin Akinc
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Circular siRNAs
- Publication number 20230257745
- Publication date Aug 17, 2023
- Alnylam Pharmaceuticals, Inc.
- Hartmut JAHNS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED RNA AGENTS WITH REDUCED OFF-TARGET EFFECT
- Publication number 20230256001
- Publication date Aug 17, 2023
- Alnylam Pharmaceuticals, Inc.
- Mark K. SCHLEGEL
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
- Publication number 20230256098
- Publication date Aug 17, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin MAIER
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Modified Double-Stranded RNA Agents
- Publication number 20230183701
- Publication date Jun 15, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin MAIER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LIPID CONTAINING FORMULATIONS
- Publication number 20230174459
- Publication date Jun 8, 2023
- ARBUTUS BIOPHARMA CORPORATION
- Muthiah Manoharan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CHIRALLY-ENRICHED DOUBLE-STRANDED RNA AGENTS
- Publication number 20230122244
- Publication date Apr 20, 2023
- Alnylam Pharmaceuticals, Inc.
- Muthiah MANOHARAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED DOUBLE-STRANDED RNA AGENTS
- Publication number 20230110876
- Publication date Apr 13, 2023
- Alnylam Pharmaceuticals, Inc.
- Martin MAIER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
- Publication number 20230068339
- Publication date Mar 2, 2023
- Alnylam Pharmaceuticals, Inc.
- Kevin FITZGERALD
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
EXTRAHEPATIC DELIVERY
- Publication number 20230016929
- Publication date Jan 19, 2023
- Alnylam Pharmaceuticals, Inc.
- Jayaprakash K. NAIR
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RNAI AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING T...
- Publication number 20230010288
- Publication date Jan 12, 2023
- Alnylam Pharmaceuticals, Inc.
- Kallanthottathil G. Rajeev
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PCSK9 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
- Publication number 20230002772
- Publication date Jan 5, 2023
- Alnylam Pharmaceuticals, Inc.
- Anna Borodovsky
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MODIFIED iRNA AGENTS
- Publication number 20220403377
- Publication date Dec 22, 2022
- Alnylam Pharmaceuticals, Inc.
- Muthiah MANOHARAN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MODIFIED OLIGONUCLEOTIDES
- Publication number 20220389419
- Publication date Dec 8, 2022
- Alnylam Pharmaceuticals, Inc.
- Muthiah MANOHARAN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MODIFIED DOUBLE-STRANDED RNA AGENTS
- Publication number 20220389424
- Publication date Dec 8, 2022
- Alnylam Pharmaceuticals, Inc.
- Martin MAIER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Muthiah Manoharan

Person

Patents Grantslast 30 patents

SERPINA1 iRNA compositions and methods of use thereof

Carbohydrate conjugates as delivery agents for oligonucleotides

Lipids and compositions for the delivery of therapeutics

Lipid compositions

Extrahepatic delivery

Carbohydrate conjugate RNA agents and process for their preparation

Complement component C5 iRNA compositions and methods of use thereof

Serpina1 iRNA compositions and methods of use thereof

Biodegradable lipids for the delivery of active agents

Carbohydrate conjugates as delivery agents for oligonucleotides

Biodegradable lipids for the delivery of active agents

Biodegradable lipids for the delivery of active agents

Biodegradable lipids for the delivery of active agents

Chirally-enriched double-stranded RNA agents

Biodegradable lipids for the delivery of active agents

Modified double-stranded RNA agents

Therapeutic compositions

Modified RNA agents with reduced off-target effect

Modified double-stranded RNA agents

Lipid containing formulations

Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof

Modified RNAi agents

Modified double-stranded RNA agents

Biodegradable lipids for the delivery of active agents

Biodegradable lipids for the delivery of active agents

Modified iRNA agents

Biodegradable lipids for the delivery of active agents

High density lipoprotein binding protein (Hdlbp/Vigilin) iRNA compo...

Complement component C5 iRNA compositions and methods of use thereof

Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof

Patents Applicationslast 30 patents

EXTRAHEPATIC DELIVERY

BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS

BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS

RNAi AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING T...

BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS

COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

CARBOHYDRATE CONJUGATED RNA AGENTS AND PROCESS FOR THEIR PREPARATION

BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS

TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FO...

MODIFIED OLIGONUCLEOTIDES

COMPOSITIONS AND METHODS FOR INHIBITION OF EXPRESSION OF APOLIPOPRO...

LIPID COMPOSITIONS

LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS

EXTRAHEPATIC DELIVERY

NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS

SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

Circular siRNAs

MODIFIED RNA AGENTS WITH REDUCED OFF-TARGET EFFECT

BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS

Modified Double-Stranded RNA Agents

LIPID CONTAINING FORMULATIONS

CHIRALLY-ENRICHED DOUBLE-STRANDED RNA AGENTS

MODIFIED DOUBLE-STRANDED RNA AGENTS

APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF

EXTRAHEPATIC DELIVERY

RNAI AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING T...

PCSK9 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

MODIFIED iRNA AGENTS

MODIFIED OLIGONUCLEOTIDES

MODIFIED DOUBLE-STRANDED RNA AGENTS