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Muthusamy Jayaraman
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Cambridge, MA, US
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Patents Grants
last 30 patents
Information
Patent Grant
Gene editing components, systems, and methods of use
Patent number
12,264,328
Issue date
Apr 1, 2025
ReNAgade Therapeutics Management, Inc.
Giedrius Gasiunas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Biodegradable lipids for the delivery of active agents
Patent number
12,239,709
Issue date
Mar 4, 2025
Alnylam Pharmaceuticals, Inc.
Martin Maier
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Constrained lipids and methods of use thereof
Patent number
12,215,068
Issue date
Feb 4, 2025
ReNAgade Therapeutics Management Inc.
Stephen Scully
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Oligonucleotide-ligand conjugates and process for their preparation
Patent number
12,173,288
Issue date
Dec 24, 2024
Alnylam Pharmaceuticals, Inc.
Muthiah Manoharan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Engineered retrons and methods of use
Patent number
12,054,739
Issue date
Aug 6, 2024
ReNAgade Therapeutics Management Inc.
Alim Ladha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipids and compositions for the delivery of therapeutics
Patent number
12,042,541
Issue date
Jul 23, 2024
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Lipid compositions
Patent number
12,023,383
Issue date
Jul 2, 2024
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Extrahepatic delivery
Patent number
12,005,074
Issue date
Jun 11, 2024
Alnylam Pharmaceuticals, Inc.
Jayaprakash K. Nair
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Engineered retrons and methods of use
Patent number
11,866,728
Issue date
Jan 9, 2024
ReNAgade Therapeutics Management Inc.
Alim Ladha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Cyclic lipids and methods of use thereof
Patent number
11,773,061
Issue date
Oct 3, 2023
ReNAgade Therapeutics Management Inc.
Muthusamy Jayaraman
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Serpina1 iRNA compositions and methods of use thereof
Patent number
11,725,207
Issue date
Aug 15, 2023
Alnylam Pharmaceuticals, Inc.
Mark K. Schlegel
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipids and compositions for the delivery of therapeutics
Patent number
11,712,476
Issue date
Aug 1, 2023
ARBUTUS BIOPHARMA CORPORATION
Muthiah Mancharan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Biodegradable lipids for the delivery of active agents
Patent number
11,679,158
Issue date
Jun 20, 2023
Alnylam Pharmaceuticals, Inc.
Martin Maier
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Biodegradable lipids for the delivery of active agents
Patent number
11,633,479
Issue date
Apr 25, 2023
Alnylam Pharmaceuticals, Inc.
Martin Maier
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Biodegradable lipids for the delivery of active agents
Patent number
11,633,480
Issue date
Apr 25, 2023
Alnylam Pharmaceuticals, Inc.
Martin Maier
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Biodegradable lipids for the delivery of active agents
Patent number
11,612,657
Issue date
Mar 28, 2023
Alnylam Pharmaceuticals, Inc.
Martin Maier
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Biodegradable lipids for the delivery of active agents
Patent number
11,590,229
Issue date
Feb 28, 2023
Alnylam Pharmaceuticals, Inc.
Martin Maier
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Modified RNA agents with reduced off-target effect
Patent number
11,504,391
Issue date
Nov 22, 2022
Alnylam Pharmaceuticals, Inc.
Mark K. Schlegel
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Lipid containing formulations
Patent number
11,420,931
Issue date
Aug 23, 2022
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Biodegradable lipids for the delivery of active agents
Patent number
11,400,158
Issue date
Aug 2, 2022
Alnylam Pharmaceuticals, Inc.
Martin Maier
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Biodegradable lipids for the delivery of active agents
Patent number
11,382,979
Issue date
Jul 12, 2022
Alnylam Pharmaceuticals, Inc.
Martin Maier
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Biodegradable lipids for the delivery of active agents
Patent number
11,246,933
Issue date
Feb 15, 2022
Alnylam Pharmaceuticals, Inc.
Martin Maier
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Lipids and compositions for the delivery of therapeutics
Patent number
11,077,197
Issue date
Aug 3, 2021
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Biodegradable lipids for the delivery of active agents
Patent number
11,071,784
Issue date
Jul 27, 2021
Alnylam Pharmaceuticals, Inc.
Martin Maier
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Serpina1 iRNA compositions and methods of use thereof
Patent number
10,995,336
Issue date
May 4, 2021
Alnylam Pharmaceuticals, Inc.
Mark K. Schlegel
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipid compositions
Patent number
10,953,095
Issue date
Mar 23, 2021
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Lipids and compositions for the delivery of therapeutics
Patent number
10,835,612
Issue date
Nov 17, 2020
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipids and compositions for the delivery of therapeutics
Patent number
10,821,186
Issue date
Nov 3, 2020
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Oligonucleotide-ligand conjugates and process for their preparation
Patent number
10,808,246
Issue date
Oct 20, 2020
Alnylam Pharmaceuticals, Inc.
Muthiah Manoharan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Lipid compositions
Patent number
10,456,473
Issue date
Oct 29, 2019
Arbutus Biopharma Corporation
Muthiah Manoharan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION
Publication number
20250075208
Publication date
Mar 6, 2025
Alnylam Pharmaceuticals, Inc.
Muthiah MANOHARAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250043279
Publication date
Feb 6, 2025
Alnylam Pharmaceuticals, Inc.
Mark K. Schlegel
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NUCLEIC ACIDS CONTAINING ABASIC NUCLEOSIDES
Publication number
20250002913
Publication date
Jan 2, 2025
Amy MCCARTHY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS
Publication number
20240424105
Publication date
Dec 26, 2024
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
Publication number
20240398956
Publication date
Dec 5, 2024
Alnylam Pharmaceuticals, Inc.
Martin MAIER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
EXTRAHEPATIC DELIVERY
Publication number
20240358738
Publication date
Oct 31, 2024
Alnylam Pharmaceuticals, Inc.
Jayaprakash K. NAIR
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
Publication number
20240285767
Publication date
Aug 29, 2024
Alnylam Pharmaceuticals, Inc.
Martin MAIER
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
Publication number
20240285768
Publication date
Aug 29, 2024
Martin MAIER
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
Publication number
20240269289
Publication date
Aug 15, 2024
Alnylam Pharmaceuticals, Inc.
Martin MAIER
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
Publication number
20240245778
Publication date
Jul 25, 2024
Martin MAIER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CYCLIC LIPIDS AND METHODS OF USE THEREOF
Publication number
20240182412
Publication date
Jun 6, 2024
Renagade Therapeutics Management Inc.
Muthusamy Jayaraman
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ENGINEERED RETRONS AND METHODS OF USE
Publication number
20240175058
Publication date
May 30, 2024
Renagade Therapeutics Management Inc.
Alim Ladha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GENE EDITING COMPONENTS, SYSTEMS, AND METHODS OF USE
Publication number
20240141382
Publication date
May 2, 2024
Renagade Therapeutics Management Inc.
Giedrius Gasiunas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LIPID NANOPARTICLES AND METHODS OF USE THEREOF
Publication number
20240130969
Publication date
Apr 25, 2024
Renagade Therapeutics Management Inc.
Muthusamy Jayaraman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENE EDITING COMPONENTS, SYSTEMS, AND METHODS OF USE
Publication number
20240084274
Publication date
Mar 14, 2024
Renagade Therapeutics Management Inc.
Giedrius Gasiunas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LIPID COMPOSITIONS
Publication number
20240066129
Publication date
Feb 29, 2024
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CONSTRAINED LIPIDS AND METHODS OF USE THEREOF
Publication number
20240067598
Publication date
Feb 29, 2024
Renagade Therapeutics Management Inc.
Stephen Scully
C07 - ORGANIC CHEMISTRY
Information
Patent Application
LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS
Publication number
20240042039
Publication date
Feb 8, 2024
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
EXTRAHEPATIC DELIVERY
Publication number
20240009225
Publication date
Jan 11, 2024
Alnylam Pharmaceuticals, Inc.
Jayaprakash K. NAIR
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS
Publication number
20230381319
Publication date
Nov 30, 2023
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODIFIED RNA AGENTS WITH REDUCED OFF-TARGET EFFECT
Publication number
20230256001
Publication date
Aug 17, 2023
Alnylam Pharmaceuticals, Inc.
Mark K. SCHLEGEL
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
Publication number
20230256098
Publication date
Aug 17, 2023
Alnylam Pharmaceuticals, Inc.
Martin MAIER
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ENGINEERED RETRONS AND METHODS OF USE
Publication number
20230235365
Publication date
Jul 27, 2023
Renagade Therapeutics Management Inc.
Alim Ladha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CYCLIC LIPIDS AND METHODS OF USE THEREOF
Publication number
20230202977
Publication date
Jun 29, 2023
Renagade Therapeutics Management Inc.
Muthusamy Jayaraman
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ACYCLIC LIPIDS AND METHODS OF USE THEREOF
Publication number
20230202966
Publication date
Jun 29, 2023
Renagade Therapeutics Management Inc.
Muthusamy Jayaraman
C07 - ORGANIC CHEMISTRY
Information
Patent Application
LIPID CONTAINING FORMULATIONS
Publication number
20230174459
Publication date
Jun 8, 2023
ARBUTUS BIOPHARMA CORPORATION
Muthiah Manoharan
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS OF SYNTHESIZING RNA MOLECULES
Publication number
20220411841
Publication date
Dec 29, 2022
CRISPR Therapeutics AG
Brian Joseph Cafferty
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
Publication number
20220370356
Publication date
Nov 24, 2022
Alnylam Pharmaceuticals, Inc.
Muthusamy Jayaraman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIODEGRADABLE LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS
Publication number
20220347302
Publication date
Nov 3, 2022
Martin Maier
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION
Publication number
20220348914
Publication date
Nov 3, 2022
Alnylam Pharmaceuticals, Inc.
Muthiah MANOHARAN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE