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Patents Grants
last 30 patents
Information
Patent Grant
4-carboxamido-isoindolinone derivatives as selective PARP-1 inhibitors
Patent number
11,773,064
Issue date
Oct 3, 2023
Nerviano Medical Sciences S.r.l.
Gianluca Mariano Enrico Papeo
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
4-carboxamido-isoindolinone derivatives as selective parp-1 inhibitors
Patent number
11,420,940
Issue date
Aug 23, 2022
Nerviano Medical Sciences S.r.l.
Gianluca Mariano Enrico Papeo
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
4-carboxamido-isoindolinone derivatives as selective PARP-1 inhibitors
Patent number
10,800,739
Issue date
Oct 13, 2020
Nerviano Medical Sciences S.r.l.
Gianluca Mariano Enrico Papeo
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Asymmetric process for the preparation of thieno-indoles derivatives
Patent number
10,556,913
Issue date
Feb 11, 2020
Nerviano Medical Sciences S.r.l.
Italo Beria
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
4-carboxamido-isoindolinone derivatives as selective PARP-1 inhibitors
Patent number
10,385,018
Issue date
Aug 20, 2019
Nerviano Medical Sciences S.r.l.
Gianluca Mariano Enrico Papeo
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Thieno[2,3-e]indole derivatives as new antitumor agents
Patent number
10,266,547
Issue date
Apr 23, 2019
Nerviano Medical Sciences S.r.l.
Marina Caldarelli
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Asymmetric process for the preparation of thieno-indoles derivatives
Patent number
10,174,048
Issue date
Jan 8, 2019
Nerviano Medical Sciences S.r.l.
Italo Beria
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted indazole derivatives active as kinase inhibitors
Patent number
10,081,622
Issue date
Sep 25, 2018
Nerviano Medical Sciences S.r.l.
Andrea Lombardi Borgia
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Thieno-indole moieties and methods of treating using the same
Patent number
10,071,074
Issue date
Sep 11, 2018
Nerviano Medical Sciences S.r.l.
Italo Beria
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Treatment of diseases through administration of N-[5-(3,5-difluoro-...
Patent number
9,649,306
Issue date
May 16, 2017
NERVIANO MEDICAL SCIENCES S.R.L.
Natale Alvaro Barbugian
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted indazole derivatives active as kinase inhibitors
Patent number
9,616,059
Issue date
Apr 11, 2017
Nerviano Medical Sciences S.r.l.
Andrea Lombardi Borgia
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Functionalized thieno-indole derivatives for the treatment of cancer
Patent number
9,561,290
Issue date
Feb 7, 2017
Nerviano Medical Sciences S.r.l.
Italo Beria
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Thieno-indole moieties and methods of treating using the same
Patent number
9,527,863
Issue date
Dec 27, 2016
Nerviano Medical Sciences S.r.l.
Italo Beria
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Unsolvated crystalline form 1 of N-[5-(3, 5-difluoro-benzyl)-1H-ind...
Patent number
9,382,235
Issue date
Jul 5, 2016
Nerviano Medical Sciences S.r.l.
Natale Alvaro Barbugian
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted indazole derivatives active as kinase inhibitors
Patent number
9,255,087
Issue date
Feb 9, 2016
Nerviano Medical Sciences S.r.l.
Andrea Lombardi Borgia
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted indazole derivatives active as kinase inhibitors
Patent number
9,102,662
Issue date
Aug 11, 2015
Nerviano Medical Sciences S.r.l.
Andrea Lombardi Borgia
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted indazole derivatives active as kinase inhibitors
Patent number
9,085,558
Issue date
Jul 21, 2015
NERVIANO MEDICAL SCIENCES S.R.L.
Andrea Lombardi Borgia
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Process for the preparation of N-[5-(3,5-difluoro-benzyl)-1H-indazo...
Patent number
9,085,565
Issue date
Jul 21, 2015
Nerviano Medical Sciences S.r.l.
Natale Alvaro Barbugian
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted indazole derivatives active as kinase inhibitors
Patent number
9,029,356
Issue date
May 12, 2015
Nerviano Medical Sciences S.r.l.
Andrea Lombardi Borgia
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Isoquinolin-1(2H)-one derivatives as PARP-1 inhibitors
Patent number
8,993,594
Issue date
Mar 31, 2015
Nerviano Medical Sciences S.r.l.
Gianluca Mariano Enrico Papeo
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted pyrrolo-pyrazole derivatives as kinase inhibitors
Patent number
8,785,448
Issue date
Jul 22, 2014
Nerviano Medical Sciences S.r.l.
Maria Gabriella Brasca
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
3-oxo-2,3-dihydro-1H-isoindole-4-carboxamides with selective PARP-1...
Patent number
8,765,972
Issue date
Jul 1, 2014
Nerviano Medical Sciences S.r.l.
Gianluca Mariano Enrico Papeo
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted indazole derivatives active as kinase inhibitors
Patent number
8,673,893
Issue date
Mar 18, 2014
Nerviano Medical Sciences S.r.l.
Andrea Lombardi Borgia
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Isoquinolin-1 (2H)-one derivatives as PARP-1 inhibitors
Patent number
8,592,416
Issue date
Nov 26, 2013
Nerviano Medical Sciences S.r.l.
Gianluca Mariano Enrico Papeo
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted pyrrolo-pyrazole derivatives as kinase inhibitors
Patent number
8,557,857
Issue date
Oct 15, 2013
Nerviano Medical Sciences S.r.l.
Maria Gabriella Brasca
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted pyrrolo-pyrazole derivatives as kinase inhibitors
Patent number
8,557,845
Issue date
Oct 15, 2013
Nerviano Medical Sciences S.r.l.
Maria Gabriella Brasca
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted pyrrolo-pyrazole derivatives as kinase inhibitors
Patent number
8,481,585
Issue date
Jul 9, 2013
Nerviano Medical Sciences S.r.l.
Maria Gabriella Brasca
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Substituted indazole derivatives active as kinase inhibitors
Patent number
8,354,399
Issue date
Jan 15, 2013
Nerviano Medical Sciences S.r.l.
Maria Menichincheri
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Substituted indazole derivatives active as kinase inhibitors
Patent number
8,299,057
Issue date
Oct 30, 2012
Nerviano Medical Sciences S.r.l.
Andrea Lombardi Borgia
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Heteroarylpyrrolopyridinones active as kinase inhibitors
Patent number
7,618,982
Issue date
Nov 17, 2009
Nerviano Medical Sciences S.r.l.
Ermes Vanotti
C07 - ORGANIC CHEMISTRY
Patents Applications
last 30 patents
Information
Patent Application
GEM-DISUBSTITUTED HETEROCYCLIC COMPOUNDS AND THEIR USE AS IDH INHIB...
Publication number
20230000871
Publication date
Jan 5, 2023
NERVIANO MEDICAL SCIENCES S.R.L.
Francesco CASUSCELLI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
4-CARBOXAMIDO-ISOINDOLINONE DERIVATIVES AS SELECTIVE PARP-1 INHIBITORS
Publication number
20220363636
Publication date
Nov 17, 2022
NERVIANO MEDICAL SCIENCES S.R.L.
Gianluca Mariano Enrico Papeo
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Publication number
20220144813
Publication date
May 12, 2022
NERVIANO MEDICAL SCIENCES S.R.L.
Andrea LOMBARDI BORGIA
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
4-CARBOXAMIDO-ISOINDOLINONE DERIVATIVES AS SELECTIVE PARP-1 INHIBITORS
Publication number
20200407314
Publication date
Dec 31, 2020
NERVIANO MEDICAL SCIENCES S.R.L.
Gianluca Mariano Enrico Papeo
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Publication number
20200377487
Publication date
Dec 3, 2020
NERVIANO MEDICAL SCIENCES S.R.L.
Andrea LOMBARDI BORGIA
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
4-CARBOXAMIDO-ISOINDOLINONE DERIVATIVES AS SELECTIVE PARP-1 INHIBITORS
Publication number
20190330151
Publication date
Oct 31, 2019
NERVIANO MEDICAL SCIENCES S.R.L.
Gianluca Mariano Enrico Papeo
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Publication number
20190241546
Publication date
Aug 8, 2019
NERVIANO MEDICAL SCIENCES S.R.L.
Andrea LOMBARDI BORGIA
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ASYMMETRIC PROCESS FOR THE PREPARATION OF THIENO-INDOLES DERIVATIVES
Publication number
20190071451
Publication date
Mar 7, 2019
NERVIANO MEDICAL SCIENCES S.R.L.
Italo BERIA
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ASYMMETRIC PROCESS FOR THE PREPARATION OF THIENO-INDOLES DERIVATIVES
Publication number
20180215768
Publication date
Aug 2, 2018
NERVIANO MEDICAL SCIENCES S.R.L.
Italo BERIA
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Publication number
20170158677
Publication date
Jun 8, 2017
NERVIANO MEDICAL SCIENCES S.R.L.
Andrea Lombardi Borgia
C07 - ORGANIC CHEMISTRY
Information
Patent Application
THIENO-INDOLE MOIETIES AND METHODS OF TREATING USING THE SAME
Publication number
20170071907
Publication date
Mar 16, 2017
NERVIANO MEDICAL SCIENCES S.R.L.
Italo Beria
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PROCESS FOR THE PREPARATION OF N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDAZO...
Publication number
20160279125
Publication date
Sep 29, 2016
NERVIANO MEDICAL SCIENCES S.R.L.
Natale Alvaro Barbugian
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
THIENO[2,3-e]INDOLE DERIVATIVES AS NEW ANTITUMOR AGENTS
Publication number
20160229867
Publication date
Aug 11, 2016
NERVIANO MEDICAL SCIENCES S.R.L.
Marina CALDARELLI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Publication number
20160095856
Publication date
Apr 7, 2016
NERVIANO MEDICAL SCIENCES S.R.L.
Andrea Lombardi Borgia
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
4-CARBOXAMIDO-ISOINDOLINONE DERIVATIVES AS SELECTIVE PARP-1 INHIBITORS
Publication number
20150274662
Publication date
Oct 1, 2015
NERVIANO MEDICAL SCIENCES S.R.L.
Gianluca Mariano Enrico Papeo
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PROCESS FOR THE PREPARATION OF N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDAZO...
Publication number
20150274707
Publication date
Oct 1, 2015
NERVIANO MEDICAL SCIENCES S.R.L.
Natale Alvaro BARBUGIAN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
FUNCTIONALIZED THIENO-INDOLE DERIVATIVES FOR THE TREATMENT OF CANCER
Publication number
20150080316
Publication date
Mar 19, 2015
NERVIANO MEDICAL SCIENCES S.R.L.
Italo Beria
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Publication number
20150065520
Publication date
Mar 5, 2015
NERVIANO MEDICAL SCIENCES S.R.L.
Andrea Lombardi Borgia
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Publication number
20150057291
Publication date
Feb 26, 2015
NERVIANO MEDICAL SCIENCES S.R.L.
Andrea Lombardi Borgia
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Publication number
20150057292
Publication date
Feb 26, 2015
NERVIANO MEDICAL SCIENCES S.R.L.
Andrea Lombardi Borgia
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PROCESS FOR THE PREPARATION OF N-[5-(3,5-DIFLUORO-BENZYL)-1H-INDAZO...
Publication number
20150051222
Publication date
Feb 19, 2015
NERVIANO MEDICAL SCIENCES S.R.L.
Natale Alvaro BARBUGIAN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ALKYLATING AGENTS
Publication number
20150051154
Publication date
Feb 19, 2015
NERVIANO MEDICAL SCIENCES S.R.L.
Italo Beria
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Publication number
20140228351
Publication date
Aug 14, 2014
NERVIANO MEDICAL SCIENCES S.R.L.
Andrea LOMBARDI BORGIA
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ISOQUINOLIN-1(2H)-ONE DERIVATIVES AS PARP-1 INHIBITORS
Publication number
20140045846
Publication date
Feb 13, 2014
NERVIANO MEDICAL SCIENCES S.R.L.
Gianluca Mariano Enrico Papeo
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SUBSTITUTED PYRROLO-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS
Publication number
20130344031
Publication date
Dec 26, 2013
NERVIANO MEDICAL SCIENCES S.R.L.
Maria Gabriella Brasca
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS
Publication number
20130018036
Publication date
Jan 17, 2013
NERVIANO MEDICAL SCIENCES S.R.L.
Andrea LOMBARDI BORGIA
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SUBSTITUTED PYRROLO-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS
Publication number
20130017170
Publication date
Jan 17, 2013
NERVIANO MEDICAL SCIENCES S.R.L.
Maria Gabriella Brasca
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SUBSTITUTED PYRROLO-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS
Publication number
20130012507
Publication date
Jan 10, 2013
NERVIANO MEDICAL SCIENCES S.R.L.
Maria Gabriella Brasca
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
3-0X0-2,3-DIHYDRO-1H-ISOINDOLE-4-CARBOXAMIDES WITH SELECTIVE PARP-1...
Publication number
20120245143
Publication date
Sep 27, 2012
NERVIANO MEDICAL SCIENCES S.R.L.
Gianluca Mariano Enrico Papeo
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ISOQUINOLIN-1 (2H) -ONE DERIVATIVES AS PARP-1 INHIBITORS
Publication number
20120157454
Publication date
Jun 21, 2012
NERVIANO MEDICAL SCIENCES S.R.L.
Gianluca Mariano Enrico Papeo
C07 - ORGANIC CHEMISTRY