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Shengdar Tsai
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Charlestown, MA, US
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Patents Grants
last 30 patents
Information
Patent Grant
Methods for increasing efficiency of nuclease-induced homology-dire...
Patent number
12,286,641
Issue date
Apr 29, 2025
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genomewide unbiased identification of DSBs evaluated by sequencing...
Patent number
12,104,207
Issue date
Oct 1, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Increasing specificity for RNA-guided genome editing
Patent number
11,920,152
Issue date
Mar 5, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
High-throughput method for characterizing the genome-wide activity...
Patent number
11,371,095
Issue date
Jun 28, 2022
St. Jude Children's Research Hospital, Inc.
Shengdar Q. Tsai
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Using RNA-guided FokI nucleases (RFNs) to increase specificity for...
Patent number
11,098,326
Issue date
Aug 24, 2021
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Full interrogation of nuclease DSBs and sequencing (FIND-seq)
Patent number
11,028,429
Issue date
Jun 8, 2021
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for increasing efficiency of nuclease-induced homology-dire...
Patent number
11,021,718
Issue date
Jun 1, 2021
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
High-throughput method for characterizing the genome-wide activity...
Patent number
10,920,272
Issue date
Feb 16, 2021
St. Jude Children's Research Hospital, Inc.
Shengdar Q. Tsai
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Increasing specificity for RNA-guided genome editing
Patent number
10,844,403
Issue date
Nov 24, 2020
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Comprehensive in vitro reporting of cleavage events by sequencing (...
Patent number
10,738,303
Issue date
Aug 11, 2020
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Using RNA-guided FokI nucleases (RFNs) to increase specificity for...
Patent number
10,544,433
Issue date
Jan 28, 2020
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Multiplex guide RNAs
Patent number
10,526,589
Issue date
Jan 7, 2020
The General Hospital Corporation
Shengdar Tsai
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genomewide unbiased identification of DSBs evaluated by sequencing...
Patent number
10,501,794
Issue date
Dec 10, 2019
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Using RNA-guided FokI nucleases (RFNs) to increase specificity for...
Patent number
10,138,476
Issue date
Nov 27, 2018
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Using RNA-guided FokI Nucleases (RFNs) to increase specificity for...
Patent number
10,011,850
Issue date
Jul 3, 2018
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Full interrogation of nuclease DSBs and sequencing (find-seq)
Patent number
9,988,674
Issue date
Jun 5, 2018
The General Hospital Corporation
J. Keith Joung
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Grant
Increasing specificity for RNA-guided genome editing
Patent number
9,885,033
Issue date
Feb 6, 2018
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Comprehensive in vitro reporting of cleavage events by sequencing (...
Patent number
9,850,484
Issue date
Dec 26, 2017
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Genomewide unbiased identification of DSBs evaluated by sequencing...
Patent number
9,822,407
Issue date
Nov 21, 2017
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Using RNA-guided FokI nucleases (RFNs) to increase specificity for...
Patent number
9,567,603
Issue date
Feb 14, 2017
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
Increasing Specificity for RNA-Guided Genome Editing
Publication number
20240240207
Publication date
Jul 18, 2024
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR INCREASING EFFICIENCY OF NUCLEASE-INDUCED HOMOLOGY-DIRE...
Publication number
20210292795
Publication date
Sep 23, 2021
The General Hospital Corporation
J. Keith JOUNG
C07 - ORGANIC CHEMISTRY
Information
Patent Application
HIGH-THROUGHPUT METHOD FOR CHARACTERIZING THE GENOME-WIDE ACTIVITY...
Publication number
20210164041
Publication date
Jun 3, 2021
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.
Shengdar Q. Tsai
C40 - COMBINATORIAL CHEMISTRY
Information
Patent Application
Increasing Specificity for RNA-Guided Genome Editing
Publication number
20210130850
Publication date
May 6, 2021
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Using RNA-guided FokI Nucleases (RFNs) to Increase Specificity for...
Publication number
20200224222
Publication date
Jul 16, 2020
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Genomewide Unbiased Identification of DSBs Evaluated by Sequencing...
Publication number
20200199665
Publication date
Jun 25, 2020
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Multiplex Guide RNAS
Publication number
20200165587
Publication date
May 28, 2020
The General Hospital Corporation
Shengdar Tsai
C07 - ORGANIC CHEMISTRY
Information
Patent Application
HIGH-THROUGHPUT METHOD FOR CHARACTERIZING THE GENOME-WIDE ACTIVITY...
Publication number
20200115750
Publication date
Apr 16, 2020
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.
Shengdar Q. Tsai
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Using RNA-guided FokI Nucleases (RFNs) to Increase Specificity for...
Publication number
20180340189
Publication date
Nov 29, 2018
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Full Interrogation of Nuclease DSBs and Sequencing (FIND-seq)
Publication number
20180265920
Publication date
Sep 20, 2018
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Comprehensive In vitro Reporting of Cleavage Events by Sequencing (...
Publication number
20180245071
Publication date
Aug 30, 2018
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR INCREASING EFFICIENCY OF NUCLEASE-INDUCED HOMOLOGY-DIRE...
Publication number
20180230494
Publication date
Aug 16, 2018
The General Hospital Corporation
J. Keith JOUNG
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Increasing Specificity for RNA-Guided Genome Editing
Publication number
20180208921
Publication date
Jul 26, 2018
The General Hospital Corporation
J. Keith Joung
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Genomewide Unbiased Identification of DSBs Evaluated by Sequencing...
Publication number
20180087104
Publication date
Mar 29, 2018
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Using RNA-guided FokI Nucleases (RFNs) to Increase Specificity for...
Publication number
20170327805
Publication date
Nov 16, 2017
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Comprehensive In Vitro Reporting of Cleavage Events by Sequencing (...
Publication number
20170088833
Publication date
Mar 30, 2017
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
FULL INTERROGATION OF NUCLEASE DSBS AND SEQUENCING (FIND-SEQ)
Publication number
20170073747
Publication date
Mar 16, 2017
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MULTIPLEX GUIDE RNAS
Publication number
20160319281
Publication date
Nov 3, 2016
The General Hospital Corporation
Shengdar Tsai
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Genomewide Unbiased Identification of DSBs Evaluated by Sequencing...
Publication number
20160304950
Publication date
Oct 20, 2016
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Using RNA-guided FokI Nucleases (RFNs) to Increase Specificity for...
Publication number
20160153003
Publication date
Jun 2, 2016
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Increasing Specificity for RNA-Guided Genome Editing
Publication number
20160024524
Publication date
Jan 28, 2016
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Using RNA-guided FokI Nucleases (RFNs) to Increase Specificity for...
Publication number
20140295556
Publication date
Oct 2, 2014
The General Hospital Corporation
J. Keith Joung
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...