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Steven Howard
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Harlow Essex, GB
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last 30 patents
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
12,202,828
Issue date
Jan 21, 2025
Astex Therapeutics Limited
Gianni Chessari
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Isoindolinone inhibitors of the MDM2-P53 interaction and process fo...
Patent number
12,077,526
Issue date
Sep 3, 2024
Astex Therapeutics Limited
Steven Howard
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Isoindolinone inhibitors of the MDM2-P53 interaction having antican...
Patent number
12,071,429
Issue date
Aug 27, 2024
Astex Therapeutics Limited
Gianni Chessari
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Heterobicyclic compounds for inhibiting the activity of SHP2
Patent number
12,037,345
Issue date
Jul 16, 2024
Taiho Pharmaceutical Co., Ltd.
Tadashi Shimamura
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Benzolactam compounds as protein kinase inhibitors
Patent number
11,939,321
Issue date
Mar 26, 2024
Otsuka Pharmaceutical Co., Ltd.
Valerio Berdini
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
11,866,428
Issue date
Jan 9, 2024
Astex Therapeutics Limited
Alison Jo-Anne Woolford
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
11,643,410
Issue date
May 9, 2023
Astex Therapeutics Limited
Gianni Chessari
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Isoindolinone inhibitors of the MDM2-P53 interaction and process fo...
Patent number
11,603,367
Issue date
Mar 14, 2023
Astex Therapeutics Limited
Steven Howard
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pharmaceutical compounds
Patent number
11,466,016
Issue date
Oct 11, 2022
Otsuka Pharmaceutical Co., Ltd.
Christopher Norbert Johnson
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Isoindolinone inhibitors of the MDM2-P53 interaction having antican...
Patent number
11,261,171
Issue date
Mar 1, 2022
Astex Therapeutics Limited
Gianni Chessari
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
11,225,476
Issue date
Jan 18, 2022
Astex Therapeutics Limited
Gianni Chessari
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Benzolactam compounds as protein kinase inhibitors
Patent number
11,001,575
Issue date
May 11, 2021
Otsuka Pharmaceutical Co., Ltd.
Valerio Berdini
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Isoindolinone inhibitors of the MDM2-p53 interaction having antican...
Patent number
10,981,898
Issue date
Apr 20, 2021
Astex Therapeutics Limited
Gianni Chessari
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
10,618,895
Issue date
Apr 14, 2020
Astex Therapeutics Limited
Gianni Chessari
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Isoindolinone inhibitors of the MDM2-p53 interaction having antican...
Patent number
10,544,132
Issue date
Jan 28, 2020
Astex Therapeutics Limited
Gianni Chessari
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Isoindolinone inhibitors of the MDM2-P53 interaction having antican...
Patent number
10,526,311
Issue date
Jan 7, 2020
Astex Therapeutics Limited
Gianni Chessari
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Benzolactam compounds as protein kinase inhibitors
Patent number
10,457,669
Issue date
Oct 29, 2019
Otsuka Pharmaceutical Co., Ltd.
Valerio Berdini
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Arylcyclohexyl pyrazoles as NRF2 regulators
Patent number
10,351,530
Issue date
Jul 16, 2019
GlaxoSmithKline Intellectual Property Development Limited
James Callahan
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
9,980,973
Issue date
May 29, 2018
Astex Therapeutics Limited
Gianni Chessari
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
9,783,538
Issue date
Oct 10, 2017
Astex Therapeutics Limited
Gianni Chessari
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
9,676,768
Issue date
Jun 13, 2017
Astex Therapeutics Limited
Alison Jo-Anne Woolford
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
9,663,512
Issue date
May 30, 2017
Astex Therapeutics Limited
Gianni Chessari
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
9,617,248
Issue date
Apr 11, 2017
Astex Therapeutics Limited
Gianni Chessari
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
9,617,283
Issue date
Apr 11, 2017
Astex Therapeutics Limited
Gianni Chessari
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
9,458,158
Issue date
Oct 4, 2016
Astex Therapeutics Limited
Ildiko Maria Buck
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Pyrrolopyrimidine compounds and their uses
Patent number
9,416,136
Issue date
Aug 16, 2016
Novartis AG
Gilbert Besong
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
9,155,743
Issue date
Oct 13, 2015
Astex Therapeutics Limited
Ildiko Maria Buck
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Bicyclic heterocycle compounds and their uses in therapy
Patent number
9,018,214
Issue date
Apr 28, 2015
Astex Therapeutics Limited
Alison Jo-Anne Woolford
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pyrazole compounds that modulate the activity of CDK, GSK and auror...
Patent number
8,778,936
Issue date
Jul 15, 2014
Astex Therapeutics Limited
Valerio Berdini
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Pyrrolopyrimidine compounds and their uses
Patent number
8,685,980
Issue date
Apr 1, 2014
Novartis AG
Gilbert Ebai Besong
C07 - ORGANIC CHEMISTRY
Patents Applications
last 30 patents
Information
Patent Application
ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICAN...
Publication number
20250092027
Publication date
Mar 20, 2025
ASTEX THERAPEUTICS LIMITED
Gianni CHESSARI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION AND PROCESS FO...
Publication number
20250074900
Publication date
Mar 6, 2025
ASTEX THERAPEUTICS LIMITED
Steven HOWARD
C07 - ORGANIC CHEMISTRY
Information
Patent Application
BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS
Publication number
20240368136
Publication date
Nov 7, 2024
OTSUKA PHARMACEUTICAL CO., LTD.
Valerio BERDINI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT
Publication number
20240262842
Publication date
Aug 8, 2024
Merck Sharp & Dohme LLC
Kazuaki SHIBATA
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT
Publication number
20240239788
Publication date
Jul 18, 2024
Merck Sharp & Dohme LLC
David L. Sloman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY
Publication number
20240199607
Publication date
Jun 20, 2024
ASTEX THERAPEUTICS LIMITED
Alison Jo-Anne Woolford
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES
Publication number
20240043428
Publication date
Feb 8, 2024
Novartis AG
Gilbert BESONG
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION AND PROCESS FO...
Publication number
20230278989
Publication date
Sep 7, 2023
ASTEX THERAPEUTICS LIMITED
Steven HOWARD
C07 - ORGANIC CHEMISTRY
Information
Patent Application
BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY
Publication number
20230227450
Publication date
Jul 20, 2023
ASTEX THERAPEUTICS LIMITED
Gianni CHESSARI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PYRAZOLO[3,4-B]PYRAZINE SHP2 PHOSPHATASE INHIBITORS
Publication number
20230049719
Publication date
Feb 16, 2023
OTSUKA PHARMACEUTICAL CO., LTD.
Steven HOWARD
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS
Publication number
20230019032
Publication date
Jan 19, 2023
OTSUKA PHARMACEUTICAL CO., LTD.
Valerio BERDINI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
HETEROBICYCLIC COMPOUNDS FOR INHIBITING THE ACTIVITY OF SHP2
Publication number
20220363693
Publication date
Nov 17, 2022
Taiho Pharmaceutical Co., Ltd.
Tadashi SHIMAMURA
C07 - ORGANIC CHEMISTRY
Information
Patent Application
BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY
Publication number
20220204503
Publication date
Jun 30, 2022
ASTEX THERAPEUTICS LIMITED
Gianni CHESSARI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICAN...
Publication number
20220106287
Publication date
Apr 7, 2022
ASTEX THERAPEUTICS LIMITED
Gianni CHESSARI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICAN...
Publication number
20210276984
Publication date
Sep 9, 2021
ASTEX THERAPEUTICS LIMITED
Gianni CHESSARI
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES
Publication number
20210253578
Publication date
Aug 19, 2021
Novartis AG
Gilbert BESONG
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY
Publication number
20210122749
Publication date
Apr 29, 2021
ASTEX THERAPEUTICS LIMITED
Alison Jo-Anne Woolford
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PHARMACEUTICAL COMPOUNDS
Publication number
20210107908
Publication date
Apr 15, 2021
OTSUKA PHARMACEUTICAL CO., LTD.
Christopher Norbert JOHNSON
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION AND PROCESS FO...
Publication number
20210101887
Publication date
Apr 8, 2021
ASTEX THERAPEUTICS LIMITED
Steven HOWARD
C07 - ORGANIC CHEMISTRY
Information
Patent Application
BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY
Publication number
20200325134
Publication date
Oct 15, 2020
ASTEX THERAPEUTICS LIMITED
Gianni CHESSARI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICAN...
Publication number
20200247789
Publication date
Aug 6, 2020
ASTEX THERAPEUCTICS LIMITED
Gianni CHESSARI
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICAN...
Publication number
20200079761
Publication date
Mar 12, 2020
ASTEX THERAPEUTICS LIMITED
Gianni CHESSARI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY
Publication number
20190375748
Publication date
Dec 12, 2019
ASTEX THERAPEUTICS LIMITED
Alison Jo-Anne Woolford
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICAN...
Publication number
20190055215
Publication date
Feb 21, 2019
ASTEX THERAPEUTICS LIMITED
Gianni CHESSARI
C07 - ORGANIC CHEMISTRY
Information
Patent Application
BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS
Publication number
20190047990
Publication date
Feb 14, 2019
OTSUKA PHARMACEUTICAL CO., LTD.
Valerio BERDINI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICAN...
Publication number
20190016708
Publication date
Jan 17, 2019
ASTEX THERAPEUTICS LIMITED
Gianni CHESSARI
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ARYLCYCLOHEXYL PYRAZOLES AS NRF2 REGULATORS
Publication number
20180282283
Publication date
Oct 4, 2018
GlaxoSmithKline Intellectual Property Development Limited
James CALLAHAN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES
Publication number
20180155351
Publication date
Jun 7, 2018
Novartis AG
Gilbert BESONG
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY
Publication number
20180065959
Publication date
Mar 8, 2018
ASTEX THERAPEUTICS LIMITED
Gianni CHESSARI
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY
Publication number
20170334907
Publication date
Nov 23, 2017
ASTEX THERAPEUTICS LIMITED
Alison Jo-Anne Woolford
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE