Thomas Machleidt

Person

Madison, WI, US

People

Patents Grantslast 30 patents

Information Patent Grant
Luciferase-based thermal shift assays
- Patent number 11,899,021
- Issue date Feb 13, 2024
- Promega Corporation
- Melanie Dart
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Process for preparing substituted imidazo[1,2-α]pyrazines
- Patent number 11,781,168
- Issue date Oct 10, 2023
- Promega Corporation
- Anton Shakhmin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Recognition of cellular target binding by a bioactive agent using i...
- Patent number 11,740,249
- Issue date Aug 29, 2023
- Promega Corporation
- Carolyn W. Hitko
- G01 - MEASURING TESTING
Information Patent Grant
Nanoluc suicide substrates
- Patent number 11,655,247
- Issue date May 23, 2023
- Promega Corporation
- Brock Binkowski
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Luciferase-based thermal shift assays
- Patent number 11,567,083
- Issue date Jan 31, 2023
- Promega Corporation
- Melanie Dart
- G01 - MEASURING TESTING
Information Patent Grant
Compositions and methods for stabilizing coelenterazine and analogs...
- Patent number 11,534,504
- Issue date Dec 27, 2022
- Promega Corporation
- Melanie Dart
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Activation of bioluminescene by structural complementation
- Patent number 11,493,504
- Issue date Nov 8, 2022
- Promega Corporation
- Andrew S. Dixon
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Internal protein tags
- Patent number 11,365,402
- Issue date Jun 21, 2022
- Promega Corporation
- Andrew S. Dixon
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Substituted imidazo[1,2-a]pyrazines as luciferase substrates
- Patent number 11,015,216
- Issue date May 25, 2021
- Promega Corporation
- Anton Shakhmin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Luciferase-based thermal shift assays
- Patent number 10,928,400
- Issue date Feb 23, 2021
- Promega Corporation
- Melanie Dart
- G01 - MEASURING TESTING
Information Patent Grant
Functionalized NANOLUC inhibitors
- Patent number 10,815,247
- Issue date Oct 27, 2020
- Promega Corporation
- Roderick G. Flemming
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Coelenterazine analogues
- Patent number 10,669,280
- Issue date Jun 2, 2020
- Promega Corporation
- Mary Hall
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Substituted imidazo[1,2-a]pyrazines as luciferase substrates
- Patent number 10,669,568
- Issue date Jun 2, 2020
- Promega Corporation
- Anton Shakhmin
- G01 - MEASURING TESTING
Information Patent Grant
Activation of bioluminescence by structural complementation
- Patent number 10,648,971
- Issue date May 12, 2020
- Promega Corporation
- Andrew S. Dixon
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Luciferase-based thermal shift assays
- Patent number 10,571,471
- Issue date Feb 25, 2020
- Promega Corporation
- Melanie Dart
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Coelenterazine analogues
- Patent number 10,428,075
- Issue date Oct 1, 2019
- Promega Corporation
- Mary Hall
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Substituted imidazo[1,2-a]pyrazines as luciferase substrates
- Patent number 10,308,975
- Issue date Jun 4, 2019
- Promega Corporation
- Anton Shakhmin
- G01 - MEASURING TESTING
Information Patent Grant
Activation of bioluminescence by structural complementation
- Patent number 10,288,605
- Issue date May 14, 2019
- Promega Corporation
- Andrew S. Dixon
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Substituted imidazo[1,2-A]pyrazines tethered to energy acceptors
- Patent number 10,280,447
- Issue date May 7, 2019
- Promega Corporation
- Mary Hall
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Activation of bioluminescence by structural complementation
- Patent number 10,184,936
- Issue date Jan 22, 2019
- Promega Corporation
- Andrew S. Dixon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Activation of bioluminescence by structural complementation
- Patent number 10,107,800
- Issue date Oct 23, 2018
- Promega Corporation
- Andrew S. Dixon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Recognition of cellular target binding by a bioactive agent using i...
- Patent number 10,067,149
- Issue date Sep 4, 2018
- Promega Corporation
- Carolyn W. Hitko
- G01 - MEASURING TESTING
Information Patent Grant
Recognition of cellular target binding by a bioactive agent using i...
- Patent number 10,024,862
- Issue date Jul 17, 2018
- Promega Corporation
- Carolyn W. Hitko
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Coelenterazine analogues
- Patent number 10,000,500
- Issue date Jun 19, 2018
- Promega Corporation
- Mary Hall
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Internal protein tags
- Patent number 9,969,991
- Issue date May 15, 2018
- Promega Corporation
- Andrew S. Dixon
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Pro-substrates for live cell applications
- Patent number 9,927,430
- Issue date Mar 27, 2018
- Promega Corporation
- Wenhui Zhou
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Substituted imidazo[1,2-a]pyrazines as luciferase substrates and pr...
- Patent number 9,924,073
- Issue date Mar 20, 2018
- Promega Corporation
- Anton Shakhmin
- H04 - ELECTRIC COMMUNICATION TECHNIQUE
Information Patent Grant
Activation of bioluminescence by structural complementation
- Patent number 9,869,670
- Issue date Jan 16, 2018
- Promega Corporation
- Andrew S. Dixon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Activation of bioluminescence by structural complementation
- Patent number 9,797,889
- Issue date Oct 24, 2017
- Promega Corporation
- Andrew S. Dixon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Activation of bioluminescence by structural complementation
- Patent number 9,797,890
- Issue date Oct 24, 2017
- Promega Corporation
- Andrew S. Dixon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING
- Publication number 20240191211
- Publication date Jun 13, 2024
- Promega Corporation
- Rachel Friedman Ohana
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED DEHALOGENASE WITH EXTENDED SURFACE LOOP REGIONS
- Publication number 20240132859
- Publication date Apr 25, 2024
- Promega Corporation
- Michael P. Killoran
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SUBSTITUTED IMIDAZO[1,2-a]PYRAZINES AS LUCIFERASE SUBSTRATES
- Publication number 20240068009
- Publication date Feb 29, 2024
- Promega Corporation
- Anton Shakhmin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CIRCULARLY PERMUTED DEHALOGENASE VARIANTS
- Publication number 20240060059
- Publication date Feb 22, 2024
- Promega Corporation
- Michael P. Killoran
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING I...
- Publication number 20230417778
- Publication date Dec 28, 2023
- Promega Corporation
- Carolyn W. Hitko
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NANOLUC SUICIDE SUBSTRATES
- Publication number 20230382908
- Publication date Nov 30, 2023
- Promega Corporation
- Brock Binkowski
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF
- Publication number 20230357266
- Publication date Nov 9, 2023
- Promega Corporation
- Matthew A. Larsen
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Application
LUCIFERASE-BASED THERMAL SHIFT ASSAYS
- Publication number 20230341410
- Publication date Oct 26, 2023
- Promega Corporation
- Melanie Dart
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION
- Publication number 20230342826
- Publication date Oct 26, 2023
- Promega Corporation
- Andrew S. Dixon
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Application
COMPOSITIONS AND METHODS FOR STABILIZING COELENTERAZINE AND ANALOGS...
- Publication number 20230092932
- Publication date Mar 23, 2023
- Promega Corporation
- Melanie Dart
- C07 - ORGANIC CHEMISTRY
Information Patent Application
INTERNAL PROTEIN TAGS
- Publication number 20210403886
- Publication date Dec 30, 2021
- Promega Corporation
- Andrew S. Dixon
- G01 - MEASURING TESTING
Information Patent Application
COELENTERAZINE ANALOGUES
- Publication number 20210254128
- Publication date Aug 19, 2021
- Promega Corporation
- Anton Shakhmin
- G01 - MEASURING TESTING
Information Patent Application
LUCIFERASE-BASED THERMAL SHIFT ASSAYS
- Publication number 20210080470
- Publication date Mar 18, 2021
- Promega Corporation
- Melanie Dart
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODIFIED POLYAMINE POLYMERS FOR DELIVERY OF BIOMOLECULES INTO CELLS
- Publication number 20200399660
- Publication date Dec 24, 2020
- Promega Corporation
- Wenhui Zhou
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR ANALYTE DETECTION USING BIOLUMINESCENCE
- Publication number 20200386748
- Publication date Dec 10, 2020
- Promega Corporation
- Thomas Kirkland
- G01 - MEASURING TESTING
Information Patent Application
ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION
- Publication number 20200292534
- Publication date Sep 17, 2020
- Promega Corporation
- Andrew S. Dixon
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COELENTERAZINE ANALOGUES
- Publication number 20200263229
- Publication date Aug 20, 2020
- Promega Corporation
- Anton Shakhmin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LUCIFERASE-BASED THERMAL SHIFT ASSAYS
- Publication number 20200174012
- Publication date Jun 4, 2020
- Promega Corporation
- Melanie Dart
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS FOR STABILIZING COELENTERAZINE AND ANALOGS...
- Publication number 20200109146
- Publication date Apr 9, 2020
- Promega Corporation
- Melanie Dart
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COELENTERAZINE ANALOGUES
- Publication number 20190389869
- Publication date Dec 26, 2019
- Promega Corporation
- Mary Hall
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
INTERNAL PROTEIN TAGS
- Publication number 20190352623
- Publication date Nov 21, 2019
- Promega Corporation
- Andrew S. Dixon
- G01 - MEASURING TESTING
Information Patent Application
NANOLUC SUICIDE SUBSTRATES
- Publication number 20190337939
- Publication date Nov 7, 2019
- Promega Corporation
- Brock Binkowski
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COELENTERAZINE ANALOGUES
- Publication number 20190241932
- Publication date Aug 8, 2019
- Promega Corporation
- Anton Shakhmin
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING I...
- Publication number 20190064192
- Publication date Feb 28, 2019
- Promega Corporation
- Carolyn W. Hitko
- G01 - MEASURING TESTING
Information Patent Application
COELENTERAZINE ANALOGUES
- Publication number 20180334463
- Publication date Nov 22, 2018
- Promega Corporation
- Mary Hall
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION
- Publication number 20180313825
- Publication date Nov 1, 2018
- Promega Corporation
- Andrew S. Dixon
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION
- Publication number 20180306782
- Publication date Oct 25, 2018
- Promega Corporation
- Andrew S. Dixon
- C07 - ORGANIC CHEMISTRY
Information Patent Application
FUNCTIONALIZED NANOLUC INHIBITORS
- Publication number 20180222916
- Publication date Aug 9, 2018
- Promega Corporation
- Roderick G. Flemming
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COELENTERAZINE ANALOGUES
- Publication number 20180223330
- Publication date Aug 9, 2018
- Promega Corporation
- Anton Shakhmin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION
- Publication number 20180196038
- Publication date Jul 12, 2018
- Promega Corporation
- Andrew S. Dixon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Thomas Machleidt

Person

Patents Grantslast 30 patents

Luciferase-based thermal shift assays

Process for preparing substituted imidazo[1,2-α]pyrazines

Recognition of cellular target binding by a bioactive agent using i...

Nanoluc suicide substrates

Luciferase-based thermal shift assays

Compositions and methods for stabilizing coelenterazine and analogs...

Activation of bioluminescene by structural complementation

Internal protein tags

Substituted imidazo[1,2-a]pyrazines as luciferase substrates

Luciferase-based thermal shift assays

Functionalized NANOLUC inhibitors

Coelenterazine analogues

Substituted imidazo[1,2-a]pyrazines as luciferase substrates

Activation of bioluminescence by structural complementation

Luciferase-based thermal shift assays

Coelenterazine analogues

Substituted imidazo[1,2-a]pyrazines as luciferase substrates

Activation of bioluminescence by structural complementation

Substituted imidazo[1,2-A]pyrazines tethered to energy acceptors

Activation of bioluminescence by structural complementation

Activation of bioluminescence by structural complementation

Recognition of cellular target binding by a bioactive agent using i...

Recognition of cellular target binding by a bioactive agent using i...

Coelenterazine analogues

Internal protein tags

Pro-substrates for live cell applications

Substituted imidazo[1,2-a]pyrazines as luciferase substrates and pr...

Activation of bioluminescence by structural complementation

Activation of bioluminescence by structural complementation

Activation of bioluminescence by structural complementation

Patents Applicationslast 30 patents

BIOLUMINESCENCE-TRIGGERED PHOTOCATALYTIC LABELING

MODIFIED DEHALOGENASE WITH EXTENDED SURFACE LOOP REGIONS

SUBSTITUTED IMIDAZO[1,2-a]PYRAZINES AS LUCIFERASE SUBSTRATES

CIRCULARLY PERMUTED DEHALOGENASE VARIANTS

RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING I...

NANOLUC SUICIDE SUBSTRATES

PHOTOACTIVATABLE COMPOUNDS AND USES THEREOF

LUCIFERASE-BASED THERMAL SHIFT ASSAYS

ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION

COMPOSITIONS AND METHODS FOR STABILIZING COELENTERAZINE AND ANALOGS...

INTERNAL PROTEIN TAGS

COELENTERAZINE ANALOGUES

LUCIFERASE-BASED THERMAL SHIFT ASSAYS

MODIFIED POLYAMINE POLYMERS FOR DELIVERY OF BIOMOLECULES INTO CELLS

COMPOSITIONS AND METHODS FOR ANALYTE DETECTION USING BIOLUMINESCENCE

ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION

COELENTERAZINE ANALOGUES

LUCIFERASE-BASED THERMAL SHIFT ASSAYS

COMPOSITIONS AND METHODS FOR STABILIZING COELENTERAZINE AND ANALOGS...

COELENTERAZINE ANALOGUES

INTERNAL PROTEIN TAGS

NANOLUC SUICIDE SUBSTRATES

COELENTERAZINE ANALOGUES

RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING I...

COELENTERAZINE ANALOGUES

ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION

ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION

FUNCTIONALIZED NANOLUC INHIBITORS

COELENTERAZINE ANALOGUES

ACTIVATION OF BIOLUMINESCENCE BY STRUCTURAL COMPLEMENTATION