Zhuoliang Chen

Person

Belmont, MA, US

People

Patents Grantslast 30 patents

Information Patent Grant
N-azaspirocycloalkane substituted N-heteroaryl compounds and compos...
- Patent number 11,952,386
- Issue date Apr 9, 2024
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compounds and compositions for inhibiting the activity of SHP2
- Patent number 11,905,283
- Issue date Feb 20, 2024
- Novartis AG
- Zhuoliang Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
1-Pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivative...
- Patent number 11,401,259
- Issue date Aug 2, 2022
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compounds and compositions for inhibiting the activity of SHP2
- Patent number 10,975,080
- Issue date Apr 13, 2021
- Novartis AG
- Jeffrey T. Bagdanoff
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
N-azaspirocycloalkane substituted N-heteroaryl compounds and compos...
- Patent number 10,968,235
- Issue date Apr 6, 2021
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compounds and compositions for inhibiting the activity of SHP2
- Patent number 10,934,285
- Issue date Mar 2, 2021
- Novartis AG
- Zhuoliang Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivative...
- Patent number 10,774,065
- Issue date Sep 15, 2020
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
N-azaspirocycloalkane substituted N-heteroaryl compounds and compos...
- Patent number 10,336,774
- Issue date Jul 2, 2019
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compounds and compositions for inhibiting the activity of SHP2
- Patent number 10,308,660
- Issue date Jun 4, 2019
- Novartis AG
- Zhuoliang Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and...
- Patent number 10,301,278
- Issue date May 28, 2019
- Novartis AG
- Zhuoliang Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compounds and compositions for inhibiting the activity of SHP2
- Patent number 10,287,266
- Issue date May 14, 2019
- Novartis AG
- Zhuoliang Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH
- Patent number 10,112,931
- Issue date Oct 30, 2018
- Novartis AG
- Thomas Raymond Caferro
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivative...
- Patent number 10,093,646
- Issue date Oct 9, 2018
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
N-azaspirocycloalkane substituted N-heteroaryl compounds and compos...
- Patent number 10,077,276
- Issue date Sep 18, 2018
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
N-azaspirocycloalkane substituted N-heteroaryl compounds and compos...
- Patent number 9,938,295
- Issue date Apr 10, 2018
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and...
- Patent number 9,815,813
- Issue date Nov 14, 2017
- Novartis AG
- Zhuoliang Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH
- Patent number 9,688,672
- Issue date Jun 27, 2017
- Novartis AG
- Thomas Raymond Caferro
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH
- Patent number 9,434,719
- Issue date Sep 6, 2016
- Novartis AG
- Thomas Raymond Caferro
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Pyridazinyl derivatives as SMO inhibitors
- Patent number 9,409,871
- Issue date Aug 9, 2016
- Novartis AG
- Feng He
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
2-piperidin-1-yl-acetamide compounds for use as tankyrase inhibitors
- Patent number 9,181,266
- Issue date Nov 10, 2015
- Novartis AG
- Atwood Kim Cheung
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Dimeric IAP inhibitors
- Patent number 8,993,523
- Issue date Mar 31, 2015
- Novartis AG
- Zhuoliang Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
(S)-N-((S)-1-cyclohexyl-2-{(S)-2-[4-4-(4-fluorobenzoyl)-thiazol-2-y...
- Patent number 8,552,003
- Issue date Oct 8, 2013
- Novartis AG
- Mark G. Charest
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
SMAC peptidometics useful as IAP inhibitors
- Patent number 8,546,336
- Issue date Oct 1, 2013
- Novartis AG
- Zhuoliang Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Pyridazinyl derivatives as smo inhibitors
- Patent number 8,481,542
- Issue date Jul 9, 2013
- Novartis AG
- Feng He
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Dimeric IAP inhibitors
- Patent number 8,445,440
- Issue date May 21, 2013
- Novartis AG
- Christopher Straub
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of IAP
- Patent number 8,338,440
- Issue date Dec 25, 2012
- Novartis AG
- Mark G. Palermo
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Inhibitors of IAP
- Patent number 8,207,183
- Issue date Jun 26, 2012
- Novartis AG
- Mark G. Palermo
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Organic compounds
- Patent number 8,058,272
- Issue date Nov 15, 2011
- Novartis AG
- Zhuoliang Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Substituted pyrazine-3-one-derivatives as IAP inhibitors
- Patent number 8,048,886
- Issue date Nov 1, 2011
- Novartis AG
- Zhuoliang Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Pyrrolydine derivatives as IAP inhibitors
- Patent number 8,044,209
- Issue date Oct 25, 2011
- Novartis AG
- Mark G. Charest
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF
- Publication number 20240269304
- Publication date Aug 15, 2024
- Novartis AG
- Matthew T. Burger
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2
- Publication number 20240199609
- Publication date Jun 20, 2024
- Novartis AG
- Zhuoliang CHEN
- C07 - ORGANIC CHEMISTRY
Information Patent Application
MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
- Publication number 20240042051
- Publication date Feb 8, 2024
- Novartis AG
- Matthew T. Burger
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIBODY DRUG CONJUGATES HAVING LINKERS COMPRISING HYDROPHILIC GROUPS
- Publication number 20230091510
- Publication date Mar 23, 2023
- Novartis AG
- Zhuoliang CHEN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
- Publication number 20230092679
- Publication date Mar 23, 2023
- Novartis AG
- Matthew T. Burger
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
- Publication number 20230081720
- Publication date Mar 16, 2023
- Novartis AG
- Matthew T. Burger
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...
- Publication number 20220396585
- Publication date Dec 15, 2022
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
1-PYRIDAZIN-/TRIAZIN-3-YL-PIPER(-AZINE)/IDINE/PYROLIDINE DERIVATIVE...
- Publication number 20220348553
- Publication date Nov 3, 2022
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2
- Publication number 20220089597
- Publication date Mar 24, 2022
- Novartis AG
- Jeffrey T. Bagdanoff
- C07 - ORGANIC CHEMISTRY
Information Patent Application
N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...
- Publication number 20220073537
- Publication date Mar 10, 2022
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...
- Publication number 20210371429
- Publication date Dec 2, 2021
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2
- Publication number 20210309663
- Publication date Oct 7, 2021
- Novartis AG
- Jeffrey T. Bagdanoff
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2
- Publication number 20210300919
- Publication date Sep 30, 2021
- Novartis AG
- Zhuoliang CHEN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
1-PYRIDAZIN-/TRIAZIN-3-YL-PIPER(-AZINE)/IDINE/PYROLIDINE DERIVATIVE...
- Publication number 20200369643
- Publication date Nov 26, 2020
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...
- Publication number 20200181168
- Publication date Jun 11, 2020
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2
- Publication number 20200002330
- Publication date Jan 2, 2020
- Novartis AG
- Zhuoliang CHEN
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2
- Publication number 20190185475
- Publication date Jun 20, 2019
- Novartis AG
- Jeffrey T. Bagdanoff
- C07 - ORGANIC CHEMISTRY
Information Patent Application
1-PYRIDAZIN-/TRIAZIN-3-YL-PIPER(-AZINE)/IDINE/PYROLIDINE DERIVATIVE...
- Publication number 20180362496
- Publication date Dec 20, 2018
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2
- Publication number 20180251471
- Publication date Sep 6, 2018
- Zhuoliang Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...
- Publication number 20180201623
- Publication date Jul 19, 2018
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2
- Publication number 20180186770
- Publication date Jul 5, 2018
- Zhuoliang Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
1-(TRIAZIN-3-YL/PYRIDAZIN-3-YL)-PIPER(-AZINE)IDINE DERIVATIVES AND...
- Publication number 20180065949
- Publication date Mar 8, 2018
- Novartis AG
- Zhuoliang Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH
- Publication number 20180051015
- Publication date Feb 22, 2018
- Novartis AG
- Thomas Raymond CAFERRO
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
1-PYRIDAZIN-/TRIAZIN-3-YL-PIPER(-AZINE)/IDINE/PYROLIDINE DERIVATIVE...
- Publication number 20170204080
- Publication date Jul 20, 2017
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...
- Publication number 20170015680
- Publication date Jan 19, 2017
- Novartis AG
- Christine Hiu-Tung Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
1-(TRIAZIN-3-YL/PYRIDAZIN-3-YL)-PIPER(-AZINE)IDINE DERIVATIVES AND...
- Publication number 20170001975
- Publication date Jan 5, 2017
- Novartis AG
- Zhuoliang Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH
- Publication number 20160318915
- Publication date Nov 3, 2016
- Novartis AG
- Thomas Raymond CAFERRO
- C07 - ORGANIC CHEMISTRY
Information Patent Application
3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH
- Publication number 20150152093
- Publication date Jun 4, 2015
- Novartis AG
- Thomas Raymond CAFERRO
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH
- Publication number 20140275083
- Publication date Sep 18, 2014
- Novartis AG
- Thomas Raymond CAFERRO
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
SMAC PEPTIDOMETICS USEFUL AS IAP INHIBITORS
- Publication number 20140004101
- Publication date Jan 2, 2014
- Novartis AG
- Zhuoliang Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Zhuoliang Chen

Person

Patents Grantslast 30 patents

N-azaspirocycloalkane substituted N-heteroaryl compounds and compos...

Compounds and compositions for inhibiting the activity of SHP2

1-Pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivative...

Compounds and compositions for inhibiting the activity of SHP2

N-azaspirocycloalkane substituted N-heteroaryl compounds and compos...

Compounds and compositions for inhibiting the activity of SHP2

1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivative...

N-azaspirocycloalkane substituted N-heteroaryl compounds and compos...

Compounds and compositions for inhibiting the activity of SHP2

1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and...

Compounds and compositions for inhibiting the activity of SHP2

3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH

1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivative...

N-azaspirocycloalkane substituted N-heteroaryl compounds and compos...

N-azaspirocycloalkane substituted N-heteroaryl compounds and compos...

1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and...

3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH

3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH

Pyridazinyl derivatives as SMO inhibitors

2-piperidin-1-yl-acetamide compounds for use as tankyrase inhibitors

Dimeric IAP inhibitors

(S)-N-((S)-1-cyclohexyl-2-{(S)-2-[4-4-(4-fluorobenzoyl)-thiazol-2-y...

SMAC peptidometics useful as IAP inhibitors

Pyridazinyl derivatives as smo inhibitors

Dimeric IAP inhibitors

Inhibitors of IAP

Inhibitors of IAP

Organic compounds

Substituted pyrazine-3-one-derivatives as IAP inhibitors

Pyrrolydine derivatives as IAP inhibitors

Patents Applicationslast 30 patents

BCL-XL INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF

COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2

MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE

ANTIBODY DRUG CONJUGATES HAVING LINKERS COMPRISING HYDROPHILIC GROUPS

MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE

MCL-1 INHIBITOR ANTIBODY-DRUG CONJUGATES AND METHODS OF USE

N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...

1-PYRIDAZIN-/TRIAZIN-3-YL-PIPER(-AZINE)/IDINE/PYROLIDINE DERIVATIVE...

COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2

N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...

N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...

COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2

COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2

1-PYRIDAZIN-/TRIAZIN-3-YL-PIPER(-AZINE)/IDINE/PYROLIDINE DERIVATIVE...

N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...

COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2

COMPOUNDS AND COMPOSITIONS FOR INHBITING THE ACTIVITY OF SHP2

1-PYRIDAZIN-/TRIAZIN-3-YL-PIPER(-AZINE)/IDINE/PYROLIDINE DERIVATIVE...

COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2

N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...

COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF SHP2

1-(TRIAZIN-3-YL/PYRIDAZIN-3-YL)-PIPER(-AZINE)IDINE DERIVATIVES AND...

3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH

1-PYRIDAZIN-/TRIAZIN-3-YL-PIPER(-AZINE)/IDINE/PYROLIDINE DERIVATIVE...

N-AZASPIROCYCLOALKANE SUBSTITUTED N-HETEROARYL COMPOUNDS AND COMPOS...

1-(TRIAZIN-3-YL/PYRIDAZIN-3-YL)-PIPER(-AZINE)IDINE DERIVATIVES AND...

3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH

3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH

3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH

SMAC PEPTIDOMETICS USEFUL AS IAP INHIBITORS