against the NGF-receptor/TNF-receptor superfamily

Industry

CPC
C07K16/2878

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Parent Industries

CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K16/00Immunoglobulins [IGs]

Current Industry

C07K16/2878against the NGF-receptor/TNF-receptor superfamily

Industries

Patents Grantslast 30 patents

Information Patent Grant
Antibodies specifically binding to CD147 and uses thereof
- Patent number 12,357,691
- Issue date Jul 15, 2025
- Alphelix Biotech Co., Ltd.
- Xiangai Zhou
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibody-modified chimeric antigen receptor modified T cell and use...
- Patent number 12,358,994
- Issue date Jul 15, 2025
- Shanghai Cell Therapy Group Co., Ltd.
- Qijun Qian
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
De novo binding domain containing polypeptides and uses thereof
- Patent number 12,358,995
- Issue date Jul 15, 2025
- Arcellx, Inc.
- David William Lafleur
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Grant
Fusion proteins for immunotherapy against cancer and infectious dis...
- Patent number 12,358,996
- Issue date Jul 15, 2025
- NAVICURE BIOPHARMACEUTICALS LIMITED
- Chia-Mao Wu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Immunomodulating polynucleotides, antibody conjugates thereof, and...
- Patent number 12,351,598
- Issue date Jul 8, 2025
- TALLAC THERAPEUTICS, INC.
- Sukumar Sakamuri
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Chimeric antigen receptors targeting BCMA and methods of use thereof
- Patent number 12,351,638
- Issue date Jul 8, 2025
- Legend Biotech USA Inc.
- Xiaohu Fan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Anti-CD30 antibodies
- Patent number 12,351,639
- Issue date Jul 8, 2025
- The Medical College of Wisconsin, Inc.
- Jeffrey A. Medin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Production of proteins in glutamine-free cell culture media
- Patent number 12,351,641
- Issue date Jul 8, 2025
- Genentech, Inc.
- Martin Gawlitzek
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Anti-TCR antibody molecules and uses thereof
- Patent number 12,351,632
- Issue date Jul 8, 2025
- Marengo Therapeutics, Inc.
- Seng-Lai Tan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Chimeric antigen receptor and CAR-T cells that bind BCMA
- Patent number 12,351,640
- Issue date Jul 8, 2025
- MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT
- Armin Rehm
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Cancer antigen targets and uses thereof
- Patent number 12,345,712
- Issue date Jul 1, 2025
- Memorial Sloan Kettering Cancer Center
- Michel Sadelain
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Grant
Gene-edited natural killer cells
- Patent number 12,344,655
- Issue date Jul 1, 2025
- CRISPR THERAPEUTICS AG
- Valentin Sluch
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
CH3 domain variant pair inducing formation of heterodimer of heavy...
- Patent number 12,344,679
- Issue date Jul 1, 2025
- AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
- Yong Sung Kim
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody molecules that bind PD-L1 and CD137
- Patent number 12,344,672
- Issue date Jul 1, 2025
- invoX Pharma Limited
- Matthew Lakins
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody variant combinations and uses thereof
- Patent number 12,338,289
- Issue date Jun 24, 2025
- GENMAB B.V.
- Rob De Jong
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Therapeutic uses of anti-GITR antibodies
- Patent number 12,331,127
- Issue date Jun 17, 2025
- REGENERON PHARMACEUTICALS, INC.
- Robert Babb
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Modified Fc fragment, antibody comprising same, and application the...
- Patent number 12,331,119
- Issue date Jun 17, 2025
- Wuhan YZY Biopharma Co., LTD.
- Jing Zhang
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Cancer and B-cell related disease therapy
- Patent number 12,325,754
- Issue date Jun 10, 2025
- University of Southampton
- Martin John Glennie
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-mesothelin antibodies
- Patent number 12,325,742
- Issue date Jun 10, 2025
- invoX Pharma Limited
- Jose Munoz-Olaya
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Spherical nucleic acids with tailored and active protein coronae
- Patent number 12,319,711
- Issue date Jun 3, 2025
- Northwestern University
- Chad A. Mirkin
- B82 - NANO-TECHNOLOGY
Information Patent Grant
Mesothelin and CD137 binding molecules
- Patent number 12,319,739
- Issue date Jun 3, 2025
- invoX Pharma Limited
- Jose Munoz-Olaya
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods for production of tissue resident memory-like T cells and u...
- Patent number 12,319,740
- Issue date Jun 3, 2025
- Board of Regents, The University of Texas System
- Cassian Yee
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Human monoclonal antibody human CD134 (OX40) and methods of making...
- Patent number 12,319,741
- Issue date Jun 3, 2025
- KYOWA KIRIN CO., LTD.
- Shinichiro Kato
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antibodies that bind TNFRSF25
- Patent number 12,319,742
- Issue date Jun 3, 2025
- Shattuck Labs, Inc.
- Suresh De Silva
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bispecific chimeric antigen receptors targeting CD20 and BCMA
- Patent number 12,311,022
- Issue date May 27, 2025
- ABELZETA INC.
- Yihong Yao
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Lymphocyte targeted lentiviral vectors
- Patent number 12,312,593
- Issue date May 27, 2025
- Kelonia Therapeutics, Inc.
- Molly R. Perkins
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
BCMA chimeric antigen receptors and uses thereof
- Patent number 12,310,988
- Issue date May 27, 2025
- Board of Regents, The University of Texas System
- Katy Rezvani
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antibodies against TIM3 and uses thereof
- Patent number 12,312,403
- Issue date May 27, 2025
- Bristol-Myers Squibb Company
- Xiao Min Schebye
- G01 - MEASURING TESTING
Information Patent Grant
Bispecific CD137-binding antibodies for T-cell activation
- Patent number 12,312,409
- Issue date May 27, 2025
- AP Biosciences, Inc.
- Jhong-Jhe You
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Non-adult human dosing of anti-CD30 antibody-drug conjugates for tr...
- Patent number 12,303,724
- Issue date May 20, 2025
- Takeda Pharmaceutical Company Limited
- Adedigbo Fasanmade
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
BIOSYNTHETIC BIOPARATOPIC OR BISPECIFIC BINDING MOLECULES WITH ENHA...
- Publication number 20250230254
- Publication date Jul 17, 2025
- JANSSEN BIOTECH, INC.
- Adam ZWOLAK
- C07 - ORGANIC CHEMISTRY
Information Patent Application
HETERODIMERIC HUMAN IgG1 POLYPEPTIDES WITH ISOELECTRIC POINT MODIFI...
- Publication number 20250230262
- Publication date Jul 17, 2025
- Xencor, Inc.
- Gregory L. Moore
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOSITIONS AND METHODS FOR EFFICIENT AND STABLE GENETIC MODIFICAT...
- Publication number 20250228940
- Publication date Jul 17, 2025
- Yale University
- Sidi Chen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VARIANT ANTIBODIES THAT BIND GAMMA-DELTA T CELL RECEPTORS
- Publication number 20250230240
- Publication date Jul 17, 2025
- LAVA THERAPEUTICS N.V.
- Paul Willem Henri Ida PARREN
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTI-CD40 ANTIBODIES AND USES THEREOF
- Publication number 20250230253
- Publication date Jul 17, 2025
- Memorial Sloan-Kettering Cancer Center
- Christopher S. HACKETT
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BIFUNCTIONAL FUSION PROTEIN COMPOSED OF IL-15 AND ANTIBODY AGAINST...
- Publication number 20250223329
- Publication date Jul 10, 2025
- Institute of Biophysics, Chinese Academy of Sciences
- Yangxin Fu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES (TILS) WITH TUMOR NECRO...
- Publication number 20250223371
- Publication date Jul 10, 2025
- Iovance Biotherapeutics, Inc.
- Michael T. Lotze
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTI-BCMA CAR TO TARGET IMMUNE-RELATED DISORDERS, COMPOSITIONS AND...
- Publication number 20250222107
- Publication date Jul 10, 2025
- HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD.
- Cyrille Joseph COHEN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CD28/OX40 BISPECIFIC ANTIBODIES
- Publication number 20250215102
- Publication date Jul 3, 2025
- SANOFI
- Gerald BESTE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER WITH L...
- Publication number 20250215112
- Publication date Jul 3, 2025
- Yuhan Corporation
- Eunjung LEE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTIGEN-BINDING PROTEIN TARGETING PD-L1 AND CD40, PREPARATION THERE...
- Publication number 20250215089
- Publication date Jul 3, 2025
- Harbour BioMed (Shanghai) Co., Ltd
- Haishan LUO
- C07 - ORGANIC CHEMISTRY
Information Patent Application
DR5 Agonist and PLK1 Inhibitor or CDK Inhibitor Combination Therapy
- Publication number 20250215101
- Publication date Jul 3, 2025
- Inhibrx Biosciences, Inc.
- William Crago
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ENHANCED CHIMERIC ANTIGEN RECEPTOR AND USE THEREOF
- Publication number 20250213694
- Publication date Jul 3, 2025
- SHANGHAI SIMNOVA BIOTECHNOLOGY CO., LTD.
- Cuiqing YANG
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTI-SIRPa ANTIBODIES AND THEIR THERAPEUTIC APPLICATIONS
- Publication number 20250215108
- Publication date Jul 3, 2025
- OSE IMMUNOTHERAPEUTICS
- Nicolas POIRIER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC ANTIGEN RECEPTORS FOR NATURAL KILLER CELLS AND USES THEREO...
- Publication number 20250213615
- Publication date Jul 3, 2025
- SHORELINE BIOSCIENCES, INC.
- Lee Andrew Boland SWANSON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC ANTIGEN RECEPTOR THERAPY IN COMBINATION WITH IL-15R AND IL15
- Publication number 20250215096
- Publication date Jul 3, 2025
- Novartis AG
- John Scholler
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTIGEN BINDING PROTEIN TARGETING CD40, AND PREPARATION THEREFOR AN...
- Publication number 20250215100
- Publication date Jul 3, 2025
- Harbour BioMed (Shanghai) Co., Ltd
- Haishan LUO
- G01 - MEASURING TESTING
Information Patent Application
RNA CONTAINING COMPOSITION FOR TREATMENT OF TUMOR DISEASES
- Publication number 20250213724
- Publication date Jul 3, 2025
- CureVac SE
- Mariola FOTIN-MLECZEK
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
THERAPEUTIC T CELL PRODUCT
- Publication number 20250213687
- Publication date Jul 3, 2025
- Tikva Allocell Pte. Ltd.
- Pei Yun Teo
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VARIANT CH3 DOMAINS ENGINEERED FOR PREFERENTIAL CH3 HETERODIMERIZAT...
- Publication number 20250215082
- Publication date Jul 3, 2025
- ADIMAB, LLC
- Caitlin STEIN
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTI-TCR ANTIBODY MOLECULES AND USES THEREOF
- Publication number 20250215085
- Publication date Jul 3, 2025
- Marengo Therapeutics, Inc.
- Seng-Lai Tan
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENETICALLY ENGINEERED ANTIBODY RESISTANT (GEAR) CELLS FOR ADOPTIVE...
- Publication number 20250205282
- Publication date Jun 26, 2025
- VyGen-Bio, Inc.
- Arnika WAGNER
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MANUFACTURING PROCESSES FOR ADOPTIVE CELL THERAPIES
- Publication number 20250207095
- Publication date Jun 26, 2025
- Memorial Sloan-Kettering Cancer Center
- Sjoukje VAN DER STEGEN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Anti-CD40 Antibodies for Use in Treatment of Sjogren's Syndrome
- Publication number 20250206833
- Publication date Jun 26, 2025
- Novartis AG
- Pascal Espie
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CD80 PROTEIN VARIANT AND CD80 FUSION PROTEIN
- Publication number 20250206801
- Publication date Jun 26, 2025
- HANGZHOU SUMGEN BIOTECH CO., LTD.
- Ming LV
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CEACAM5-DEPENDENT 4-1BB-AGONISTIC BISPECIFIC ANTIBODIES
- Publication number 20250206834
- Publication date Jun 26, 2025
- LaNova Medicines Limited
- Runsheng Li
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
BINDING FUSION PROTEINS, BINDING FUSION PROTEIN-DRUG CONJUGATES, XT...
- Publication number 20250197912
- Publication date Jun 19, 2025
- Amunix Pharmaceuticals, Inc.
- Volker Schellenberger
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TRAILshort ANTIBODY AND METHODS OF USE
- Publication number 20250197517
- Publication date Jun 19, 2025
- Mayo Foundation for Medical Education and Research
- Andrew D. Badley
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
USE OF ANTIGEN PRESENTING CELLS TO ENHANCE CAR-T CELL THERAPY
- Publication number 20250195651
- Publication date Jun 19, 2025
- Celledit LLC
- Biliang HU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC ANTIGEN RECEPTOR COMPRISING BCMA NANOBODY LINKED TO A CHIM...
- Publication number 20250195657
- Publication date Jun 19, 2025
- Neomics Pharmaceuticals LLC
- William A. COMRIE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

against the NGF-receptor/TNF-receptor superfamily

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Antibodies specifically binding to CD147 and uses thereof

Antibody-modified chimeric antigen receptor modified T cell and use...

De novo binding domain containing polypeptides and uses thereof

Fusion proteins for immunotherapy against cancer and infectious dis...

Immunomodulating polynucleotides, antibody conjugates thereof, and...

Chimeric antigen receptors targeting BCMA and methods of use thereof

Anti-CD30 antibodies

Production of proteins in glutamine-free cell culture media

Anti-TCR antibody molecules and uses thereof

Chimeric antigen receptor and CAR-T cells that bind BCMA

Cancer antigen targets and uses thereof

Gene-edited natural killer cells

CH3 domain variant pair inducing formation of heterodimer of heavy...

Antibody molecules that bind PD-L1 and CD137

Antibody variant combinations and uses thereof

Therapeutic uses of anti-GITR antibodies

Modified Fc fragment, antibody comprising same, and application the...

Cancer and B-cell related disease therapy

Anti-mesothelin antibodies

Spherical nucleic acids with tailored and active protein coronae

Mesothelin and CD137 binding molecules

Methods for production of tissue resident memory-like T cells and u...

Human monoclonal antibody human CD134 (OX40) and methods of making...

Antibodies that bind TNFRSF25

Bispecific chimeric antigen receptors targeting CD20 and BCMA

Lymphocyte targeted lentiviral vectors

BCMA chimeric antigen receptors and uses thereof

Antibodies against TIM3 and uses thereof

Bispecific CD137-binding antibodies for T-cell activation

Non-adult human dosing of anti-CD30 antibody-drug conjugates for tr...

Patents Applicationslast 30 patents

BIOSYNTHETIC BIOPARATOPIC OR BISPECIFIC BINDING MOLECULES WITH ENHA...

HETERODIMERIC HUMAN IgG1 POLYPEPTIDES WITH ISOELECTRIC POINT MODIFI...

COMPOSITIONS AND METHODS FOR EFFICIENT AND STABLE GENETIC MODIFICAT...

VARIANT ANTIBODIES THAT BIND GAMMA-DELTA T CELL RECEPTORS

ANTI-CD40 ANTIBODIES AND USES THEREOF

BIFUNCTIONAL FUSION PROTEIN COMPOSED OF IL-15 AND ANTIBODY AGAINST...

EXPANSION OF TUMOR INFILTRATING LYMPHOCYTES (TILS) WITH TUMOR NECRO...

ANTI-BCMA CAR TO TARGET IMMUNE-RELATED DISORDERS, COMPOSITIONS AND...

CD28/OX40 BISPECIFIC ANTIBODIES

PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER WITH L...

ANTIGEN-BINDING PROTEIN TARGETING PD-L1 AND CD40, PREPARATION THERE...

DR5 Agonist and PLK1 Inhibitor or CDK Inhibitor Combination Therapy

ENHANCED CHIMERIC ANTIGEN RECEPTOR AND USE THEREOF

ANTI-SIRPa ANTIBODIES AND THEIR THERAPEUTIC APPLICATIONS

CHIMERIC ANTIGEN RECEPTORS FOR NATURAL KILLER CELLS AND USES THEREO...

CHIMERIC ANTIGEN RECEPTOR THERAPY IN COMBINATION WITH IL-15R AND IL15

ANTIGEN BINDING PROTEIN TARGETING CD40, AND PREPARATION THEREFOR AN...

RNA CONTAINING COMPOSITION FOR TREATMENT OF TUMOR DISEASES

THERAPEUTIC T CELL PRODUCT

VARIANT CH3 DOMAINS ENGINEERED FOR PREFERENTIAL CH3 HETERODIMERIZAT...

ANTI-TCR ANTIBODY MOLECULES AND USES THEREOF

GENETICALLY ENGINEERED ANTIBODY RESISTANT (GEAR) CELLS FOR ADOPTIVE...

MANUFACTURING PROCESSES FOR ADOPTIVE CELL THERAPIES

Anti-CD40 Antibodies for Use in Treatment of Sjogren's Syndrome

CD80 PROTEIN VARIANT AND CD80 FUSION PROTEIN

CEACAM5-DEPENDENT 4-1BB-AGONISTIC BISPECIFIC ANTIBODIES

BINDING FUSION PROTEINS, BINDING FUSION PROTEIN-DRUG CONJUGATES, XT...

TRAILshort ANTIBODY AND METHODS OF USE

USE OF ANTIGEN PRESENTING CELLS TO ENHANCE CAR-T CELL THERAPY

CHIMERIC ANTIGEN RECEPTOR COMPRISING BCMA NANOBODY LINKED TO A CHIM...