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by transforming the C-terminal amino acid to amides
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General methods for the preparation of peptides
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by transforming the C-terminal amino acid to amides
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last 30 patents
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Patent Grant
Process for the preparation of plecanatide
Patent number
12,162,957
Issue date
Dec 10, 2024
ENZENE BIOSCIENCES LIMITED
Sandip Adak
C07 - ORGANIC CHEMISTRY
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Patent Grant
Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugatio...
Patent number
11,634,540
Issue date
Apr 25, 2023
Nektar Therapeutics
Sean M. Culbertson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Method for producing amide compound
Patent number
11,512,108
Issue date
Nov 29, 2022
Chubu University Educational Foundation
Hisashi Yamamoto
C07 - ORGANIC CHEMISTRY
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Patent Grant
Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugatio...
Patent number
11,220,575
Issue date
Jan 11, 2022
Nektar Therapeutics
Sean M. Culbertson
C08 - ORGANIC MACROMOLECULAR COMPOUNDS THEIR PREPARATION OR CHEMICAL WORKING-...
Information
Patent Grant
Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugatio...
Patent number
10,759,906
Issue date
Sep 1, 2020
Nektar Therapeutics
Sean M. Culbertson
C07 - ORGANIC CHEMISTRY
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Patent Grant
Method for synthesizing etelcalcetide
Patent number
10,647,742
Issue date
May 12, 2020
HYBIO PHARMACEUTICAL CO., LTD.
Yonghan Chen
C07 - ORGANIC CHEMISTRY
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Patent Grant
Codon optimization for titer and fidelity improvement
Patent number
10,487,133
Issue date
Nov 26, 2019
Sutro Biopharma, Inc.
Gang Yin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Cyclic amino acid molecules and methods of preparing the same
Patent number
10,385,099
Issue date
Aug 20, 2019
The Governing Council of the University of Toronto
Andrei Yudin
C07 - ORGANIC CHEMISTRY
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Patent Grant
Coryneform bacterium and method for producing heterologous fusion p...
Patent number
10,077,447
Issue date
Sep 18, 2018
Ajinomoto Co., Inc.
Sergey Vasilievich Smirnov
C07 - ORGANIC CHEMISTRY
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Patent Grant
Method for preparing peptides by assembling multiple peptide fragments
Patent number
10,072,041
Issue date
Sep 11, 2018
Centre National de la Recherche Scientifique
Oleg Melnyk
C07 - ORGANIC CHEMISTRY
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Patent Grant
Method for producing peptide hydrazide, peptide amide, and peptide...
Patent number
10,053,491
Issue date
Aug 21, 2018
Ajinomoto Co., Inc.
Akira Otaka
C07 - ORGANIC CHEMISTRY
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Patent Grant
Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugatio...
Patent number
9,579,392
Issue date
Feb 28, 2017
Nektar Therapeutics
Sean M. Culbertson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Processes for forming amide bonds and compositions related thereto
Patent number
9,382,193
Issue date
Jul 5, 2016
Emory University
Lanny S. Liebeskind
C07 - ORGANIC CHEMISTRY
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Patent Grant
C-terminal amidation of polypeptides
Patent number
9,249,181
Issue date
Feb 2, 2016
Amylin Pharmaceuticals, LLC
Chengzao Sun
C07 - ORGANIC CHEMISTRY
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Patent Grant
Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugatio...
Patent number
9,228,053
Issue date
Jan 5, 2016
Nektar Therapeutics
Sean M. Culbertson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Boc and Fmoc solid phase peptide synthesis
Patent number
9,090,654
Issue date
Jul 28, 2015
Ipsen Manufacturing Ireland Limited
Catherine Fiona Dalton
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Processes for forming amide bonds and compositions related thereto
Patent number
8,921,599
Issue date
Dec 30, 2014
Emory University
Lanny S. Liebeskind
C07 - ORGANIC CHEMISTRY
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Patent Grant
Method of producing a modified (poly) peptide
Patent number
8,729,228
Issue date
May 20, 2014
University of Geneva
Paolo Botti
C07 - ORGANIC CHEMISTRY
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Patent Grant
Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugatio...
Patent number
8,492,503
Issue date
Jul 23, 2013
Nektar Therapeutics
Sean M. Culbertson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Boc and Fmoc solid phase peptide synthesis
Patent number
8,383,770
Issue date
Feb 26, 2013
Ipsen Manufacturing Ireland Limited
Catherine Fiona Dalton
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Fullerene-based amino acids
Patent number
8,217,137
Issue date
Jul 10, 2012
William Marsh Rice University
Andrew R. Barron
B82 - NANO-TECHNOLOGY
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Patent Grant
Composition for palladium-mediated cleavage of peptides containing...
Patent number
8,153,762
Issue date
Apr 10, 2012
Medtronic, Inc.
Barton Holmquist
C07 - ORGANIC CHEMISTRY
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Patent Grant
Auxiliary for amide bond formation
Patent number
7,718,598
Issue date
May 18, 2010
The University of Queensland
Mark Leslie Smythe
C07 - ORGANIC CHEMISTRY
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Patent Grant
Process for the synthesis of peptides amides by side-chain attachme...
Patent number
7,691,968
Issue date
Apr 6, 2010
Avecia Biologics Limited
David John Evans
C07 - ORGANIC CHEMISTRY
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Patent Grant
Peptide amidation process
Patent number
7,462,690
Issue date
Dec 9, 2008
Restoragen, Inc.
Barton Holmquist
C07 - ORGANIC CHEMISTRY
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Patent Grant
Method for modifying protein or peptide C-terminal
Patent number
7,294,707
Issue date
Nov 13, 2007
Shimadzu Corporation
Takashi Nakazawa
C07 - ORGANIC CHEMISTRY
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Patent Grant
Apparatus and method for automated protein design
Patent number
6,950,754
Issue date
Sep 27, 2005
The California Institute of Technology
Stephen L. Mayo
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Apparatus and method for automated protein design
Patent number
6,804,611
Issue date
Oct 12, 2004
California Institute of Technology
Stephen L. Mayo
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Apparatus and method for automated protein design
Patent number
6,801,861
Issue date
Oct 5, 2004
California Institute of Technology
Stephen L. Mayo
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Apparatus and method for automated protein design
Patent number
6,792,356
Issue date
Sep 14, 2004
California Institute of Technology
Stephen L. Mayo
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
FORMATION OF AMIDINES AND INTRAMOLECULAR REACTION THEREOF
Publication number
20240300888
Publication date
Sep 12, 2024
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Brett VanVeller
C07 - ORGANIC CHEMISTRY
Information
Patent Application
REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE CO...
Publication number
20240209020
Publication date
Jun 27, 2024
Chubu University Educational Foundation
Hisashi YAMAMOTO
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PEPTIDE SYNTHESIS METHOD INVOLVING STERICALLY HINDERED MIXED ANHYDR...
Publication number
20240174713
Publication date
May 30, 2024
AMICOAT AS
Jacobus Johannes Eksteen
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PEPTIDE COMPOUND PRODUCTION METHOD
Publication number
20240124516
Publication date
Apr 18, 2024
Chubu University Educational Foundation
Hisashi YAMAMOTO
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PREPARATION METHOD FOR SAMPLE TO BE ANALYZED, ANALYSIS METHOD, AND...
Publication number
20220299408
Publication date
Sep 22, 2022
SHIMADZU CORPORATION
Takashi NISHIKAZE
C07 - ORGANIC CHEMISTRY
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Patent Application
POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATIO...
Publication number
20220081512
Publication date
Mar 17, 2022
Nektar Therapeutics
Sean M. Culbertson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHOD FOR PREPARING INTERLEUKIN-2 OR INTERLEUKIN-2 ANALOGUES
Publication number
20210155665
Publication date
May 27, 2021
ETH ZURICH
Jeffrey BODE
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHOD FOR PRODUCING AMIDE COMPOUND
Publication number
20210147473
Publication date
May 20, 2021
Chubu University Educational Foundation
Hisashi YAMAMOTO
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHOD FOR PRODUCING AMIDE
Publication number
20210130393
Publication date
May 6, 2021
YOKOGAWA ELECTRIC CORPORATION
Shinichiro FUSE
C07 - ORGANIC CHEMISTRY
Information
Patent Application
POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATIO...
Publication number
20200354518
Publication date
Nov 12, 2020
Nektar Therapeutics
Sean M. Culbertson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHOD FOR PREPARING INTERLEUKIN-2 OR INTERLEUKIN-2 ANALOGUES
Publication number
20190023760
Publication date
Jan 24, 2019
ETH ZURICH
Jeffrey BODE
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHOD FOR SYNTHESIZING ETELCALCETIDE
Publication number
20190010185
Publication date
Jan 10, 2019
HYBIO PHARMACEUTICAL CO., LTD.
Yonghan CHEN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATIO...
Publication number
20180327546
Publication date
Nov 15, 2018
Nektar Therapeutics
Sean M. Culbertson
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CODON OPTIMIZATION FOR TITER AND FIDELITY IMPROVEMENT
Publication number
20180051065
Publication date
Feb 22, 2018
Sutro Biopharma, Inc.
Gang Yin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
C-TERMINAL AMIDATION OF POLYPEPTIDES
Publication number
20140058070
Publication date
Feb 27, 2014
AstraZeneca Pharmaceuticala LP
Chengzao Sun
C07 - ORGANIC CHEMISTRY
Information
Patent Application
BOC AND FMOC SOLID PHASE PEPTIDE SYNTHESIS
Publication number
20130338337
Publication date
Dec 19, 2013
IPSEN MANUFACTURING IRELAND LIMITED
Catherine Fiona DALTON
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Method For Preparing Peptides By Assembling Multiple Peptide Fragments
Publication number
20130331545
Publication date
Dec 12, 2013
UNIVERSITE DE LILLE 1 SCIENCES ET TECHNOLOGIES
Oleg Melnyk
C07 - ORGANIC CHEMISTRY
Information
Patent Application
POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATIO...
Publication number
20130280783
Publication date
Oct 24, 2013
Sean M. CULBERTSON
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Processes For Forming Amide Bonds And Compositions Related Thereto
Publication number
20120107902
Publication date
May 3, 2012
Emory University
Lanny S. Liebeskind
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Polymeric Alpha-Hydroxy Aldehyde and Ketone Reagents and Conjugatio...
Publication number
20110230618
Publication date
Sep 22, 2011
Nektar Therapeutics
Sean M. Culbertson
C08 - ORGANIC MACROMOLECULAR COMPOUNDS THEIR PREPARATION OR CHEMICAL WORKING-...
Information
Patent Application
BOC AND FMOC SOLID PHASE PEPTIDE SYNTHESIS
Publication number
20100160604
Publication date
Jun 24, 2010
Ipsen Manufacturing Ireland Limited
Catherine Fiona Dalton
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Method Of Producing A Modified (POLY) Peptide
Publication number
20090220452
Publication date
Sep 3, 2009
UNIVERSITY OF GENEVA
Paolo Botti
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PEPTIDE AMIDATION PROCESS
Publication number
20090215987
Publication date
Aug 27, 2009
Barton Holmquist
C07 - ORGANIC CHEMISTRY
Information
Patent Application
FULLERENE-BASED AMINO ACIDS
Publication number
20090197315
Publication date
Aug 6, 2009
William Marsh Rice University
Andrew R. Barron
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Method of Peptide Synthesis
Publication number
20080200648
Publication date
Aug 21, 2008
Lonza AG
Matthieu Giraud
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Apparatus and method for automated protein design
Publication number
20070032961
Publication date
Feb 8, 2007
Stephen L. Mayo
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Methods for the production of peptide derivatives
Publication number
20060276626
Publication date
Dec 7, 2006
Avi Tovi
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Apparatus and method for automated protein design
Publication number
20060259247
Publication date
Nov 16, 2006
Stephen L. Mayo
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Apparatus and method for automated protein design
Publication number
20060019316
Publication date
Jan 26, 2006
Stephen L. Mayo
C07 - ORGANIC CHEMISTRY
Information
Patent Application
Peptide amidation process
Publication number
20050287632
Publication date
Dec 29, 2005
Barton Holmquist
C07 - ORGANIC CHEMISTRY