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Coagulation factor Xa (3.4.21.6)
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CPC
C12N9/6432
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CHEMISTRY METALLURGY
C12
Biochemistry
C12N
MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N9/00
Enzymes Proenzymes Compositions thereof Processes for preparing, activating, inhibiting, separating or purifying enzymes
Current Industry
C12N9/6432
Coagulation factor Xa (3.4.21.6)
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Patents Grants
last 30 patents
Information
Patent Grant
Highly potent ISVD compounds capable of substituting for FVIII(A)
Patent number
12,098,400
Issue date
Sep 24, 2024
Novo Nordisk A/S
Andreas Vegge
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Prohemostatic proteins for the treatment of bleeding
Patent number
12,083,170
Issue date
Sep 10, 2024
Academisch Ziekenhuis Leiden
Daniël Verhoef
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lyophilized formulations for factor XA antidote
Patent number
12,005,144
Issue date
Jun 11, 2024
Alexion Pharmaceuticals, Inc.
Phuong M. Nguyen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Preparation of factor Xa derivatives
Patent number
11,845,966
Issue date
Dec 19, 2023
Alexion Pharmaceuticals, Inc.
Mark Karbarz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antidotes for factor Xa inhibitors and methods of using the same
Patent number
11,839,646
Issue date
Dec 12, 2023
Alexion Pharmaceuticals, Inc.
Genmin Lu
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Peptides that inhibit binding of EPCR to its ligand to treat inflam...
Patent number
11,820,833
Issue date
Nov 21, 2023
Tel HaShomer Medical Research Infrastructure and Services Ltd.
Nicola Maggio
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Prohemostatic proteins for the treatment of bleeding
Patent number
11,357,836
Issue date
Jun 14, 2022
Academisch Ziekenhuis Leiden
Daniël Verhoef
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Prohemostatic proteins for the treatment of bleeding
Patent number
11,304,995
Issue date
Apr 19, 2022
Academisch Ziekenhuis Leiden
Daniël Verhoef
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Procoagulant compounds
Patent number
11,261,437
Issue date
Mar 1, 2022
Bioverativ Therapeutics Inc.
Vu Phong Hong
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Chimeric clotting factors
Patent number
11,168,316
Issue date
Nov 9, 2021
Bioverativ Therapeutics, Inc.
Joe Salas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Mutated factor X polypeptides and uses thereof for the treatment of...
Patent number
11,085,032
Issue date
Aug 10, 2021
INSERM (Institut National de la Sante et de la Recherche Medicale)
Olivier Christophe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lyophilized formulations for factor Xa antidote
Patent number
11,028,382
Issue date
Jun 8, 2021
Alexion Pharmaceuticals, Inc.
Juan Wang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Chimeric clotting factors
Patent number
10,968,442
Issue date
Apr 6, 2021
Bioverativ Therapeutics Inc.
Joe Salas
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Antidotes for factor Xa inhibitors and methods of using the same
Patent number
10,954,503
Issue date
Mar 23, 2021
Alexion Pharmaceuticals, Inc.
Uma Sinha
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Preparation of factor Xa derivatives
Patent number
10,954,504
Issue date
Mar 23, 2021
Alexion Pharmaceuticals, Inc.
Mark Karbarz
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Processable single chain molecules and polypeptides made using same
Patent number
10,927,362
Issue date
Feb 23, 2021
Bioverativ Therapeutics Inc.
Joe Salas
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Unit dose formulation of antidotes for factor Xa inhibitors and met...
Patent number
10,765,726
Issue date
Sep 8, 2020
Portola Pharmaceuticals, Inc.
Uma Sinha
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Protein purification by anion exchange chromatography
Patent number
10,723,761
Issue date
Jul 28, 2020
Baxalta Incorporated
Artur Mitterer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antidotes for factor Xa inhibitors and methods of using the same
Patent number
10,675,335
Issue date
Jun 9, 2020
Portola Pharmaceuticals, Inc.
Genmin Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Mutated factor X polypeptides and uses thereof for the treatment of...
Patent number
10,676,730
Issue date
Jun 9, 2020
INSERM (Institut National de la Sante et de la Recherche Medicale)
Olivier Christophe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for purifying FXa variant proteins
Patent number
10,660,946
Issue date
May 26, 2020
Pfizer Inc.
Keith A. Johnson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Mutated factor X polypeptides and uses thereof for the treatment of...
Patent number
10,655,119
Issue date
May 19, 2020
INSERM (Institut National de la Sante et de la Recherche Medicale)
Olivier Christophe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Non-cytotoxic protein conjugates
Patent number
10,619,146
Issue date
Apr 14, 2020
Ipsen Bioinnovation Limited
Keith Foster
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Preparation of factor Xa derivatives
Patent number
10,604,748
Issue date
Mar 31, 2020
Portola Pharmaceuticals, Inc.
Mark Karbarz
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Compositions and methods for counteracting Factor Xa inhibition
Patent number
10,588,950
Issue date
Mar 17, 2020
Pfizer Inc.
Debra D. Pittman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Prohemostatic proteins for the treatment of bleeding
Patent number
10,537,618
Issue date
Jan 21, 2020
Academisch Ziekenhuis Leiden
Daniël Verhoef
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Factor X mutants
Patent number
10,364,424
Issue date
Jul 30, 2019
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES
Jean-Luc Plantier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Procoagulant compounds
Patent number
10,287,564
Issue date
May 14, 2019
Bioverativ Therapeutics Inc.
Vu Phong Hong
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Chimeric clotting factors
Patent number
10,202,595
Issue date
Feb 12, 2019
Bioverativ Therapeutics Inc.
Joe Salas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antidotes for factor Xa inhibitors and methods of using the same
Patent number
10,190,111
Issue date
Jan 29, 2019
Portola Pharmaceuticals, Inc.
Uma Sinha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND MET...
Publication number
20240189401
Publication date
Jun 13, 2024
Alexion Pharmaceuticals, Inc.
Uma Sinha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME
Publication number
20240082367
Publication date
Mar 14, 2024
Alexion Pharmaceuticals, Inc.
Genmin Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PREPARATION OF FACTOR XA DERIVATIVES
Publication number
20240076642
Publication date
Mar 7, 2024
Alexion Pharmaceuticals, Inc.
Mark Karbarz
C07 - ORGANIC CHEMISTRY
Information
Patent Application
HIGHLY POTENT ISVD COMPOUNDS CAPABLE OF SUBSTITUTING FOR FVIII(A)
Publication number
20240067944
Publication date
Feb 29, 2024
Novo Nordisk A/S
Andreas Vegge
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PROCESS FOR MAKING RECOMBINANT ANTIDOTE TO FACTOR XA INHIBITOR
Publication number
20230383276
Publication date
Nov 30, 2023
Alexion Pharmaceuticals, Inc.
Genmin Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND MET...
Publication number
20230000957
Publication date
Jan 5, 2023
Alexion Pharmaceuticals, Inc.
Uma Sinha
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
LYOPHILIZED FORMULATIONS FOR FACTOR XA ANTIDOTE
Publication number
20220354792
Publication date
Nov 10, 2022
Alexion Pharmaceuticals, Inc.
Phuong M. Nguyen
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PROHEMOSTATIC PROTEINS FOR THE TREATMENT OF BLEEDING
Publication number
20220288172
Publication date
Sep 15, 2022
Academisch Ziekenhuis Leiden
Daniël VERHOEF
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR PREPARING FACTOR XA AND DERIVATIVES
Publication number
20220251534
Publication date
Aug 11, 2022
Alexion Pharmaceuticals, Inc.
Genmin Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PROCOAGULANT COMPOUNDS
Publication number
20220243189
Publication date
Aug 4, 2022
Bioverativ Therapeutics Inc.
Vu Phong HONG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CHIMERIC CLOTTING FACTORS
Publication number
20220135959
Publication date
May 5, 2022
Bioverativ Therapeutics Inc.
Joe SALAS
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PROCESS FOR MAKING RECOMBINANT ANTIDOTE TO FACTOR XA INHIBITOR
Publication number
20220098565
Publication date
Mar 31, 2022
Alexion Pharmaceuticals, Inc.
Genmin Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR XA DERIVA...
Publication number
20210379163
Publication date
Dec 9, 2021
Alexion Pharmaceuticals, Inc.
Genmin Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTIDOTES TO FACTOR XA INHIBITORS
Publication number
20210371842
Publication date
Dec 2, 2021
Alexion Pharmaceuticals, Inc.
Pamela B. Conley
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CHIMERIC CLOTTING FACTORS
Publication number
20210355473
Publication date
Nov 18, 2021
Bioverativ Therapeutics Inc.
Joe SALAS
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PREPARATION OF FACTOR XA DERIVATIVES
Publication number
20210348149
Publication date
Nov 11, 2021
Alexion Pharmaceuticals, Inc.
Mark Karbarz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME
Publication number
20210340515
Publication date
Nov 4, 2021
Alexion Pharmaceuticals, Inc.
Uma Sinha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PROCESSABLE SINGLE CHAIN MOLECULES AND POLYPEPTIDES MADE USING SAME
Publication number
20210292729
Publication date
Sep 23, 2021
Bioverativ Therapeutics Inc.
Joe Salas
C07 - ORGANIC CHEMISTRY
Information
Patent Application
LYOPHILIZED FORMULATIONS FOR FACTOR XA ANTIDOTE
Publication number
20210284986
Publication date
Sep 16, 2021
Alexion Pharmaceuticals, Inc.
Juan Wang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS COMPRISING HETEROGENEOUS POPULATIONS OF RECOMBINANT HU...
Publication number
20210106658
Publication date
Apr 15, 2021
Pfizer Inc.
KEITH A. JOHNSON
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND MET...
Publication number
20210085762
Publication date
Mar 25, 2021
Portola Pharmaceuticals, Inc.
UMA SINHA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR COUNTERACTING FACTOR XA INHIBITION
Publication number
20210000930
Publication date
Jan 7, 2021
Pfizer Inc.
Debra D. Pittman
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MUTATED FACTOR X POLYPEPTIDES AND USES THEREOF FOR THE TREATMENT OF...
Publication number
20200299666
Publication date
Sep 24, 2020
Inserm (institut National de la Sante et de la Recherche Medicale)
Olivier CHRISTOPHE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
LYOPHILIZED FORMULATIONS FOR FACTOR XA ANTIDOTE
Publication number
20200299667
Publication date
Sep 24, 2020
Portola Pharmaceuticals, Inc.
Juan Wang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
LYOPHILIZED FORMULATIONS FOR FACTOR XA ANTIDOTE
Publication number
20200299668
Publication date
Sep 24, 2020
Portola Pharmaceuticals, Inc.
Juan Wang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME
Publication number
20200276280
Publication date
Sep 3, 2020
Portola Pharmaceuticals, Inc.
GENMIN LU
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MUTATED FACTOR X POLYPEPTIDES AND USES THEREOF FOR THE TREATMENT OF...
Publication number
20200248162
Publication date
Aug 6, 2020
Inserm (institut National de la Sante et de la Recherche Medicale)
Olivier CHRISTOPHE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PREPARATION OF FACTOR XA DERIVATIVES
Publication number
20200208131
Publication date
Jul 2, 2020
Portola Pharmaceuticals, Inc.
Mark Karbarz
C07 - ORGANIC CHEMISTRY
Information
Patent Application
PROHEMOSTATIC PROTEINS FOR THE TREATMENT OF BLEEDING
Publication number
20200138917
Publication date
May 7, 2020
Academisch Ziekenhuis Leiden
Daniël VERHOEF
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PROHEMOSTATIC PROTEINS FOR THE TREATMENT OF BLEEDING
Publication number
20200138916
Publication date
May 7, 2020
Academisch Ziekenhuis Leiden
Daniël VERHOEF
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE