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containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)
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C07K2319/95
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Organic chemistry
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PEPTIDES
C07K2319/00
Fusion polypeptide
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C07K2319/95
containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)
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last 30 patents
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Self-inactivating rabies virus vector encoding a nucleoprotein and...
Patent number
12,203,092
Issue date
Jan 21, 2025
Mironid Limited
Marco Tripodi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Enhanced hAT family transposon-mediated gene transfer and associate...
Patent number
12,037,611
Issue date
Jul 16, 2024
R & D Systems, Inc.
David Largaespada
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Tunable endogenous protein degradation with heterobifunctional comp...
Patent number
12,023,385
Issue date
Jul 2, 2024
Dana-Farber Cancer Institute, Inc.
Dennis Buckley
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compositions and methods for selective protein degradation
Patent number
11,999,802
Issue date
Jun 4, 2024
Novartis AG
James E. Bradner
G01 - MEASURING TESTING
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Tagged chimeric effector molecules and receptors thereof
Patent number
11,993,652
Issue date
May 28, 2024
FRED HUTCHINSON CANCER CENTER
Stanley R. Riddell
C07 - ORGANIC CHEMISTRY
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Methods of treating spinal cord injury using a chondroitin sulfate...
Patent number
11,981,711
Issue date
May 14, 2024
The Cleveland Clinic Foundation
Yu-Shang Lee
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Immunogenic compositions targeting recurrent cancer mutations and m...
Patent number
11,897,927
Issue date
Feb 13, 2024
Advaxis, Inc.
Robert Petit
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Bi-functional anti-tau polypeptides and use thereof
Patent number
11,827,683
Issue date
Nov 28, 2023
Regenerative Research Foundation
Sally Temple
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Method for robust control of gene expression
Patent number
11,820,794
Issue date
Nov 21, 2023
California Institute of Technology
Michael J. Flynn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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CRISPR/Cas system and method for genome editing and modulating tran...
Patent number
11,788,088
Issue date
Oct 17, 2023
The Board of Trustees of the University of Illinois
Ryan E. Clarke
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Compositions and methods for inducing conformational changes in cer...
Patent number
11,733,233
Issue date
Aug 22, 2023
Celgene Corporation
Brian E. Cathers
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Targeted disruption of T cell receptor genes using engineered zinc...
Patent number
11,439,666
Issue date
Sep 13, 2022
Sangamo Therapeutics, Inc.
Maria Chiara Bonini
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Targeted protein degradation
Patent number
11,427,643
Issue date
Aug 30, 2022
GlaxoSmithKline Intellectual Property Development Limited
Lewis Lee Brayshaw
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Cytotoxic molecules responsive to intracellular ligands for selecti...
Patent number
11,384,350
Issue date
Jul 12, 2022
The Regents of the University of California
Yvonne Y. Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Methods and compositions for the positive selection of protein dest...
Patent number
11,340,216
Issue date
May 24, 2022
Dana-Farber Cancer Institute, Inc.
William G. Kaelin
C07 - ORGANIC CHEMISTRY
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Methods and compositions for reducing the immunogenicity of chimeri...
Patent number
11,325,957
Issue date
May 10, 2022
Cell Design Labs, Inc.
Amy Gilbert
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Anti-rho GTPase conformational single domain antibodies and uses th...
Patent number
11,319,381
Issue date
May 3, 2022
INSERM (INSTITUT NATIONAL DE LA SANTÉET DE LA RECHERCHE MÉDICALE)
Aurelien Olichon
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Selective degradation of proteins
Patent number
11,306,306
Issue date
Apr 19, 2022
SyntheX, Inc.
Charly Chahwan
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Tunable endogenous protein degradation
Patent number
11,293,023
Issue date
Apr 5, 2022
Dana-Farber Cancer Institute, Inc.
Dennis Buckley
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Targeted protein silencing using chimeras between antibodies and ub...
Patent number
11,192,942
Issue date
Dec 7, 2021
Cornell University
Matthew DeLisa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Peptide directed protein knockdown
Patent number
11,186,620
Issue date
Nov 30, 2021
University of British Columbia
Yu Tian Wang
C07 - ORGANIC CHEMISTRY
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Immune modulation
Patent number
11,173,206
Issue date
Nov 16, 2021
SEMENTIS LIMITED
Paul Michael Howley
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Methods of identifying a polypeptide target for degradation by a mo...
Patent number
11,168,345
Issue date
Nov 9, 2021
The Broad Institute, Inc.
Tarjei Mikkelsen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Enhanced hAT family transposon-mediated gene transfer and associate...
Patent number
11,162,084
Issue date
Nov 2, 2021
B-Mogen Biotechnologies, Inc.
David Largaespada
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Sequence arrangements and sequences for neoepitope presentation
Patent number
11,154,597
Issue date
Oct 26, 2021
NantCell, Inc.
Kayvan Niazi
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Chromatography resin, production and use thereof
Patent number
11,124,539
Issue date
Sep 21, 2021
CYTIVA BIOPROCESS R&D AB
Johan William Ohman
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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Method for expressing and purifying soluble protein of CRM197
Patent number
11,124,548
Issue date
Sep 21, 2021
FORBIOKOREA CO., LTD.
Hyeon Cheol Lee
C07 - ORGANIC CHEMISTRY
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Enhanced hAT family transposon-mediated gene transfer and associate...
Patent number
11,111,483
Issue date
Sep 7, 2021
B-Mogen Biotechnologies, Inc.
David Largaespada
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Ubiquitin interacting motif peptides as therapeutics
Patent number
11,084,852
Issue date
Aug 10, 2021
Oklahoma Medical Research Foundation
Yunzhou Dong
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Bi-functional anti-tau polypeptides and use thereof
Patent number
11,072,639
Issue date
Jul 27, 2021
Regenerative Research Foundation
Sally Temple
C07 - ORGANIC CHEMISTRY
Patents Applications
last 30 patents
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Patent Application
BACTERIAL SYSTEMS FOR ANALYZING UBIQUITYLATED POLYPEPTIDES
Publication number
20250019737
Publication date
Jan 16, 2025
Technology Innovation Momentum Fund (Israel) Limited Partnership
Gali PRAG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
NUCLEIC ACID MOLECULES, FUSION PROTEINS, AND MRNA VACCINES WITH ENH...
Publication number
20250000959
Publication date
Jan 2, 2025
WESTGENE BIOPHARMA CO., LTD.
Xiangrong SONG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
METHODS AND USES FOR NDFIP1 FUSION POLYPEPTIDES IN TREATING NEURODE...
Publication number
20240391967
Publication date
Nov 28, 2024
UNIVERSITY HEALTH NETWORK
Michael George FEHLINGS
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION
Publication number
20240384007
Publication date
Nov 21, 2024
Novartis AG
James E. Bradner
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
RECOMBINANT VIRUS CONTAINING DEGRON, PREPARATION METHOD THEREFOR, A...
Publication number
20240342268
Publication date
Oct 17, 2024
SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
Longlong SI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
BIO PROTAC PROTEIN HAVING INTRACELLULAR DELIVERY FUNCTION, AND PHAR...
Publication number
20240287206
Publication date
Aug 29, 2024
NIBEC CO., LTD.
Yoon Jeong PARK
C07 - ORGANIC CHEMISTRY
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Patent Application
CRISPR/CAS SYSTEM AND METHOD FOR GENOME EDITING AND MODULATING TRAN...
Publication number
20240247262
Publication date
Jul 25, 2024
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
Ryan E. Clarke
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CONDITIONAL DEGRADATION OF PROTEINS THAT ARE LOCALIZED AT THE PLASM...
Publication number
20240228563
Publication date
Jul 11, 2024
The Regents of the University of California
Andrew H. NG
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MODIFICATION OF RNA-RELATED ENZYMES FOR ENHANCED PRODUCTION
Publication number
20240175065
Publication date
May 30, 2024
Translate Bio, Inc.
Bettina Strack-Logue
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CONDITIONAL DEGRADATION OF PROTEINS THAT ARE LOCALIZED AT THE PLASM...
Publication number
20240132560
Publication date
Apr 25, 2024
The Regents of the University of California
Andrew H. NG
C07 - ORGANIC CHEMISTRY
Information
Patent Application
IMMUNOGENIC COMPOSITIONS TARGETING RECURRENT CANCER MUTATIONS AND M...
Publication number
20240124540
Publication date
Apr 18, 2024
Advaxis, Inc.
Robert Petit
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
METHODS OF REGULATING ADENO-ASSOCIATED VIRUS PRODUCTION
Publication number
20240101972
Publication date
Mar 28, 2024
Spark Therapeutics, Inc.
Mustafa Yazicioglu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
SECRETABLE PAYLOAD REGULATION
Publication number
20240091358
Publication date
Mar 21, 2024
Senti Biosciences, Inc.
Michelle Elizabeth HUNG
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Application
WW-DOMAIN-ACTIVATED EXTRACELLULAR VESICLES TARGETING CORONAVIRUSES
Publication number
20230391834
Publication date
Dec 7, 2023
President and Fellows of Harvard College
Quan Lu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PROTEIN TAG TO INDUCE LIGAND DEPENDENT DEGRADATION OF PROTEIN/PROTE...
Publication number
20230234957
Publication date
Jul 27, 2023
Dana-Farber Cancer Institute, Inc.
Eric Fischer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
BETA-ARRESTIN COMPOSITIONS AND ASSOCIATED METHODS
Publication number
20230227514
Publication date
Jul 20, 2023
DUKE UNIVERSITY
Sudha SHENOY
G01 - MEASURING TESTING
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Patent Application
RECOMBINANT VECTOR OF THERMOLABILE UNG FUSED PROTEIN AND AN EXPRESS...
Publication number
20230193234
Publication date
Jun 22, 2023
XIAMEN UNIVERSITY
Yongyou ZHANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
CHIMERIC POLYPEPTIDES
Publication number
20230159615
Publication date
May 25, 2023
Outpace Bio, Inc.
Howell MOFFETT
C07 - ORGANIC CHEMISTRY
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Patent Application
ZINC FINGER DEGRADATION DOMAINS
Publication number
20230151342
Publication date
May 18, 2023
THE BROAD INSTITUTE, INC.
Amit CHOUDHARY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Composition and Methods for Selective Degradation of Engineered Pro...
Publication number
20230095912
Publication date
Mar 30, 2023
Celgene Corporation
Christopher Walton Carroll
C07 - ORGANIC CHEMISTRY
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Patent Application
COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN EXPRESSION
Publication number
20230071283
Publication date
Mar 9, 2023
Andrei Golosov
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PROTEIN TAG TO INDUCE LIGAND DEPENDENT DEGRADATION OF PROTEIN/PROTE...
Publication number
20220402981
Publication date
Dec 22, 2022
Dana-Farber Cancer Institute, Inc.
Eric S. Fischer
C07 - ORGANIC CHEMISTRY
Information
Patent Application
NONHUMAN ANIMAL AND USE FOR SAME
Publication number
20220378024
Publication date
Dec 1, 2022
Inter-University Research Institute Corporation Research Organization of Info...
Masato KANEMAKI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR THE POSITIVE SELECTION OF PROTEIN DEST...
Publication number
20220357311
Publication date
Nov 10, 2022
Dana-Farber Cancer Institute, Inc.
William G. Kaelin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TARGETED PROTEIN SILENCING USING CHIMERAS BETWEEN ANTIBODIES AND UB...
Publication number
20220348644
Publication date
Nov 3, 2022
Cornell University
Matthew Delisa
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
SELECTIVE DEGRADATION OF PROTEINS
Publication number
20220298503
Publication date
Sep 22, 2022
SyntheX, Inc.
Charly Chahwan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
COMPOSITIONS FOR REGULATING AND SELF-INACTIVATING ENZYME EXPRESSION...
Publication number
20220298500
Publication date
Sep 22, 2022
The Trustees of the University of Pennsylvania
James M. Wilson
C07 - ORGANIC CHEMISTRY
Information
Patent Application
CHEMICALLY INDUCIBLE POLYPEPTIDE POLYMERIZATION
Publication number
20220281931
Publication date
Sep 8, 2022
Dana-Farber Cancer Institute, Inc.
Benjamin EBERT
C07 - ORGANIC CHEMISTRY
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Patent Application
COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION
Publication number
20220251152
Publication date
Aug 11, 2022
Novartis AG
Seth Carbonneau
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ANTI-RHO GTPASE CONFORMATIONAL SINGLE DOMAIN ANTIBODIES AND USES TH...
Publication number
20220213221
Publication date
Jul 7, 2022
Inserm (institut National de la Sante et de la Recherche Medicale)
Aurelien OLICHON
C07 - ORGANIC CHEMISTRY