containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)

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C07K2319/95

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CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K2319/00Fusion polypeptide

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C07K2319/95containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)

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Patents Grantslast 30 patents

Information Patent Grant
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containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Methods of treating spinal cord injury using a supressor of cytokin...

Methods and compositions for reducing the immunogenicity of chimeri...

Method for robust control of gene expression

Self-inactivating rabies virus vector encoding a nucleoprotein and...

Enhanced hAT family transposon-mediated gene transfer and associate...

Tunable endogenous protein degradation with heterobifunctional comp...

Compositions and methods for selective protein degradation

Tagged chimeric effector molecules and receptors thereof

Methods of treating spinal cord injury using a chondroitin sulfate...

Immunogenic compositions targeting recurrent cancer mutations and m...

Bi-functional anti-tau polypeptides and use thereof

Method for robust control of gene expression

CRISPR/Cas system and method for genome editing and modulating tran...

Compositions and methods for inducing conformational changes in cer...

Targeted disruption of T cell receptor genes using engineered zinc...

Targeted protein degradation

Cytotoxic molecules responsive to intracellular ligands for selecti...

Methods and compositions for the positive selection of protein dest...

Methods and compositions for reducing the immunogenicity of chimeri...

Anti-rho GTPase conformational single domain antibodies and uses th...

Selective degradation of proteins

Tunable endogenous protein degradation

Targeted protein silencing using chimeras between antibodies and ub...

Peptide directed protein knockdown

Immune modulation

Methods of identifying a polypeptide target for degradation by a mo...

Enhanced hAT family transposon-mediated gene transfer and associate...

Sequence arrangements and sequences for neoepitope presentation

Chromatography resin, production and use thereof

Method for expressing and purifying soluble protein of CRM197

Patents Applicationslast 30 patents

ZINC FINGER DEGRON SEQUENCES

METHODS AND COMPOSITIONS FOR CONTROLLING T CELL ACTIVATION

COMPOSITIONS COMPRISING MODIFIED FLAVIVIRUS E GLYCOPROTEINS AND MET...

FUSION PROTEIN FOR TARGETING RECOMBINANT PROTEINS FOR DEGRADATION

AUXIN-DEGRON SYSTEM KIT AND USE THEREFOR

METHODS AND COMPOSITIONS FOR DETERMINING THE ANTIGEN SPECIFICITY OF...

ENGINEERED MCP AND PCP PROTEINS AND SYSTEMS AND METHODS THEREOF

REGULATED SYNTHETIC GENE ACTIVATION SYSTEMS

TARGETED DEGRADATION OF ALPHA-SYNUCLEIN

BACTERIAL SYSTEMS FOR ANALYZING UBIQUITYLATED POLYPEPTIDES

NUCLEIC ACID MOLECULES, FUSION PROTEINS, AND MRNA VACCINES WITH ENH...

METHODS AND USES FOR NDFIP1 FUSION POLYPEPTIDES IN TREATING NEURODE...

COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION

RECOMBINANT VIRUS CONTAINING DEGRON, PREPARATION METHOD THEREFOR, A...

BIO PROTAC PROTEIN HAVING INTRACELLULAR DELIVERY FUNCTION, AND PHAR...

CRISPR/CAS SYSTEM AND METHOD FOR GENOME EDITING AND MODULATING TRAN...

CONDITIONAL DEGRADATION OF PROTEINS THAT ARE LOCALIZED AT THE PLASM...

MODIFICATION OF RNA-RELATED ENZYMES FOR ENHANCED PRODUCTION

CONDITIONAL DEGRADATION OF PROTEINS THAT ARE LOCALIZED AT THE PLASM...

IMMUNOGENIC COMPOSITIONS TARGETING RECURRENT CANCER MUTATIONS AND M...

METHODS OF REGULATING ADENO-ASSOCIATED VIRUS PRODUCTION

SECRETABLE PAYLOAD REGULATION

WW-DOMAIN-ACTIVATED EXTRACELLULAR VESICLES TARGETING CORONAVIRUSES

PROTEIN TAG TO INDUCE LIGAND DEPENDENT DEGRADATION OF PROTEIN/PROTE...

BETA-ARRESTIN COMPOSITIONS AND ASSOCIATED METHODS

RECOMBINANT VECTOR OF THERMOLABILE UNG FUSED PROTEIN AND AN EXPRESS...

CHIMERIC POLYPEPTIDES

ZINC FINGER DEGRADATION DOMAINS

Composition and Methods for Selective Degradation of Engineered Pro...

COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN EXPRESSION