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Dihydrofolate reductase [DHFR] (1.5.1.3)
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C12N9/003
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C12
Biochemistry
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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N9/00
Enzymes Proenzymes Compositions thereof Processes for preparing, activating, inhibiting, separating or purifying enzymes
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C12N9/003
Dihydrofolate reductase [DHFR] (1.5.1.3)
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Patents Grants
last 30 patents
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Patent Grant
Production of soluble recombinant proteins without N-terminal methi...
Patent number
12,104,161
Issue date
Oct 1, 2024
Fina BioSolutions LLC
Min-Ju Chang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
DHFR tunable protein regulation
Patent number
12,104,178
Issue date
Oct 1, 2024
Obsidian Therapeutics, Inc.
Vipin Suri
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for treatment of ocular disorders and blin...
Patent number
12,097,267
Issue date
Sep 24, 2024
The Trustees of the University of Pennsylvania
Jeannette Bennicelli
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for decoupling yield and productivity of a non-catabolic co...
Patent number
12,098,407
Issue date
Sep 24, 2024
Amyris Inc.
Penelope R. Chua
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Fusion protein between short form rod-derived cone viability factor...
Patent number
12,076,367
Issue date
Sep 3, 2024
Pharma Cinq, LLC
Tianci Luo
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Destabilising domains for conditionally stabilising a protein
Patent number
12,049,650
Issue date
Jul 30, 2024
BRAINGENE AB
Mauno Vihinen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for selective protein degradation
Patent number
11,999,802
Issue date
Jun 4, 2024
Novartis AG
James E. Bradner
G01 - MEASURING TESTING
Information
Patent Grant
Engineered imine reductases and methods for the reductive amination...
Patent number
11,987,818
Issue date
May 21, 2024
Codexis, Inc.
Margie Tabuga Borra-Garske
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Immunotherapy against neuronal and brain tumors
Patent number
11,986,497
Issue date
May 21, 2024
Immatics Biotechnologies GmbH
Toni Weinschenk
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Artificial organelles for enzymatic cofactor reduction
Patent number
11,981,948
Issue date
May 14, 2024
ENSOVI, INC.
Kyle A. Minor
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Programmable protein circuits in living cells
Patent number
11,965,191
Issue date
Apr 23, 2024
California Institute of Technology
Xiaojing Gao
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Sensors, methods and kits for detecting NADPH based on resonance en...
Patent number
11,959,121
Issue date
Apr 16, 2024
Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V.
Qiuliyang Yu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions, devices and methods for the control in vitro of chemi...
Patent number
11,920,153
Issue date
Mar 5, 2024
Alma Mater Studiorum—Università di Bologna
Stefania Rapino
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Quantification method of ethanolamine phosphate, oxidoreductase for...
Patent number
11,879,149
Issue date
Jan 23, 2024
Kikkoman Corporation
Atsushi Ichiyanagi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Protein prostheses for mitochondrial diseases or conditions
Patent number
11,866,736
Issue date
Jan 9, 2024
The General Hospital Corporation
Vamsi Mootha
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Yeast cells having reductive TCA pathway from pyruvate to succinate...
Patent number
11,821,021
Issue date
Nov 21, 2023
Cargill, Incorporated
Arlene M. Fosmer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Targeted DNA demethylation and methylation
Patent number
11,780,895
Issue date
Oct 10, 2023
The Jackson Laboratory
Albert Cheng
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Microorganisms for diterpene production
Patent number
11,725,223
Issue date
Aug 15, 2023
DSM IP Assets B.V.
Viktor Marius Boer
A23 - FOODS OR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
Information
Patent Grant
Systems and methods for enzymatic A1C detection and quantification
Patent number
11,703,513
Issue date
Jul 18, 2023
Polymer Technology Systems, Inc.
Gary Hughes
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Immunotherapy against neuronal and brain tumors
Patent number
11,648,276
Issue date
May 16, 2023
Immatics Biotechnologies GmbH
Toni Weinschenk
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Protein enriched microvesicles and methods of making and using the...
Patent number
11,643,635
Issue date
May 9, 2023
Takara Bio USA, Inc.
Michael Haugwitz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
DHFR tunable protein regulation
Patent number
11,629,340
Issue date
Apr 18, 2023
Obsidian Therapeutics, Inc.
Vipin Suri
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for the targeting of SOD1
Patent number
11,613,742
Issue date
Mar 28, 2023
Scribe Therapeutics Inc.
Benjamin Oakes
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified amadoriase and method for producing the same, agent for im...
Patent number
11,549,134
Issue date
Jan 10, 2023
Kikkoman Corporation
Yosuke Masakari
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Artificial organelles for enzymatic cofactor reduction
Patent number
11,535,880
Issue date
Dec 27, 2022
ENSOVI, INC.
Kyle A. Minor
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Multipartite signaling proteins and uses thereof
Patent number
11,530,265
Issue date
Dec 20, 2022
2seventy bio, Inc.
Jordan Jarjour
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Therapeutic agents specifically delivered by exosomes for cancer tr...
Patent number
11,517,530
Issue date
Dec 6, 2022
The Board of Trustees of the Leland Stanford Junior University
Jing-Hung Wang
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Diagnosis and therapy of multiple sclerosis
Patent number
11,505,592
Issue date
Nov 22, 2022
PRINDEX S.R.L.
Roberto Paterno
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Amadoriase having enhanced dehydrogenase activity
Patent number
11,499,143
Issue date
Nov 15, 2022
Kikkoman Corporation
Yosuke Masakari
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified sarcosine oxidase, and gene and production method therefor
Patent number
11,479,757
Issue date
Oct 25, 2022
Kikkoman Corporation
Eriko Yoshihara
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION
Publication number
20240384007
Publication date
Nov 21, 2024
Novartis AG
James E. Bradner
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
FUSION PROTEIN BETWEEN SHORT FORM ROD-DERIVED CONE VIABILITY FACTOR...
Publication number
20240374683
Publication date
Nov 14, 2024
PHARMA CINQ, LLC
Tianci LUO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CONJUGATES AND METHODS OF USE THEREOF
Publication number
20240327804
Publication date
Oct 3, 2024
Regents of the University of Minnesota
Carston R. Wagner
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compositions And Methods For Enhancing Immunotherapy
Publication number
20240285683
Publication date
Aug 29, 2024
The Trustees of Princeton University
Joshua D. Rabinowitz
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS, DEVICES AND METHODS FOR THE CONTROL IN VITRO OF CHEMI...
Publication number
20240254436
Publication date
Aug 1, 2024
ALMA MATER STUDIORUM-UNIVERSITA' DI BOLOGNA
Stefania RAPINO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION...
Publication number
20240254457
Publication date
Aug 1, 2024
Codexis, Inc.
Margie Borra-Garsek
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CONTROL OF PROTEIN EXPRESSION WITH TMP-PROTAC COMPOUNDS
Publication number
20240226100
Publication date
Jul 11, 2024
The Trustees of the University of Pennsylvania
Mark A. SELLMYER
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
M6A-COUPLED EFFECTOR PROTEIN EXPRESSION SYSTEM AND METHODS OF MAKIN...
Publication number
20240207446
Publication date
Jun 27, 2024
DUKE UNIVERSITY
Kathryn Meyer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
STRATEGIES TO PREVENT AND/OR TREAT IMMUNE RESPONSES TO SOLUBLE ALLO...
Publication number
20240207379
Publication date
Jun 27, 2024
ImCyse SA
Jean-Marie Saint-Remy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Tropane Alkaloid Transporters and Methods of Making Tropane Alkaloi...
Publication number
20240191267
Publication date
Jun 13, 2024
The Board of Trustees of the Leland Stanford Junior University
Christina D. Smolke
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHOD FOR PRODUCING DEMETHYLATED COMPOUND
Publication number
20240167066
Publication date
May 23, 2024
DAICEL CORPORATION
Akira OTANI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PROTEIN PROSTHESES FOR MITOCHONDRIAL DISEASES OR CONDITIONS
Publication number
20240158765
Publication date
May 16, 2024
The General Hospital Corporation
Vamsi MOOTHA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
IMMUNOGENIC PEPTIDES AND THEIR USE IN TRANSPLANTATION
Publication number
20240158464
Publication date
May 16, 2024
ImCyse SA
Jean-Marie Saint-Remy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TARGETED DNA DEMETHYLATION AND METHYLATION
Publication number
20240132557
Publication date
Apr 25, 2024
The Jackson Laboratory
Albert Cheng
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES
Publication number
20240124904
Publication date
Apr 18, 2024
Genomatica, Inc.
Anthony P. Burgard
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR THE TARGETING OF SOD1
Publication number
20240101984
Publication date
Mar 28, 2024
Scribe Therapeutics Inc.
Benjamin OAKES
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS OF REGULATING ADENO-ASSOCIATED VIRUS PRODUCTION
Publication number
20240101972
Publication date
Mar 28, 2024
Spark Therapeutics, Inc.
Mustafa Yazicioglu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MICROORGANISMS FOR DITERPENE PRODUCTION
Publication number
20240068002
Publication date
Feb 29, 2024
DSM IP Assets B. V.
Viktor Marius BOER
A23 - FOODS OR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
Information
Patent Application
ARTIFICIAL ORGANELLES FOR ENZYMATIC COFACTOR REDUCTION
Publication number
20240068003
Publication date
Feb 29, 2024
ENSOVI, INC.
Kyle A. Minor
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
YEAST CELLS HAVING REDUCTIVE TCA PATHWAY FROM PYRUVATE TO SUCCINATE...
Publication number
20240052383
Publication date
Feb 15, 2024
Cargill, Incorporated
Arlene M. FOSMER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PRODUCTION OF NMN AND ITS DERIVATIVES VIA MICROBIAL PROCESSES
Publication number
20240043894
Publication date
Feb 8, 2024
Conagen Inc.
David Nunn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SYNTHETIC PROTEIN-LEVEL NEURAL NETWORK IN MAMMALIAN CELLS
Publication number
20240011010
Publication date
Jan 11, 2024
California Institute of Technology
Zibo Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Recombinant Production of Steviol Glycosides
Publication number
20230407360
Publication date
Dec 21, 2023
EVOLVA SA
Jens Houghton-Larsen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PRETREATMENT METHOD, PRESERVATION METHOD, AUTOMATIC TREATMENT SYSTE...
Publication number
20230393042
Publication date
Dec 7, 2023
JIANGSU QLIFE MEDICAL TECHNOLOGY GROUP CO., LTD.
Xiaoliang CHENG
G01 - MEASURING TESTING
Information
Patent Application
HETEROLOGOUS PROTEINS WITH AXONEMAL PROTEINS
Publication number
20230340036
Publication date
Oct 26, 2023
The Regents of the University of California
Wallace F. MARSHALL
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MULTIPARTITE SIGNALING PROTEINS AND USES THEREOF
Publication number
20230287111
Publication date
Sep 14, 2023
2seventy bio, Inc.
Jordan Jarjour
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
REAL-TIME CELLULAR THERMAL SHIFT ASSAY (RT-CETSA) FOR RESEARCH AND...
Publication number
20230257756
Publication date
Aug 17, 2023
The United States of America,as represented by the Secretary,Department of He...
Mark J. Henderson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NOVEL IMMUNOTHERAPY AGAINST NEURONAL AND BRAIN TUMORS
Publication number
20230241111
Publication date
Aug 3, 2023
Immatics Biotechnologies GmbH
Toni WEINSCHENK
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Protein Enriched Microvesicles and Methods of Making and Using the...
Publication number
20230235278
Publication date
Jul 27, 2023
Takara Bio USA, Inc.
Michael Haugwitz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ARTIFICIAL ORGANELLES FOR ENZYMATIC COFACTOR REDUCTION
Publication number
20230212632
Publication date
Jul 6, 2023
ENSOVI, INC.
Kyle A. Minor
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...