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C12N2310/343
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C12
Biochemistry
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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N2310/00
Structure or type of the nucleic acid
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C12N2310/343
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Patents Grants
last 30 patents
Information
Patent Grant
SERPINA1 iRNA compositions and methods of use thereof
Patent number
12,071,619
Issue date
Aug 27, 2024
Alnylam Pharmaceuticals, Inc.
Alfica Sehgal
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Two-tailed self-delivering siRNA
Patent number
12,049,627
Issue date
Jul 30, 2024
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
SiRNA structures for high activity and reduced off target
Patent number
11,926,831
Issue date
Mar 12, 2024
Nitto Denko Corporation
Kenjirou Minomi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for the specific inhibition of alpha-1 ant...
Patent number
11,912,996
Issue date
Feb 27, 2024
Dicerna Pharmaceuticals, Inc.
Bob Dale Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Alpha-1 antitrypsin (AAT) RNAi agents, compositions including AAT R...
Patent number
11,884,920
Issue date
Jan 30, 2024
Arrowhead Pharmaceuticals, Inc.
Zhen Li
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for the specific inhibition of alpha-1 ant...
Patent number
11,851,658
Issue date
Dec 26, 2023
Dicerna Pharmaceuticals, Inc.
Bob Dale Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for inhibiting gene expression of Hif2alpha
Patent number
11,840,688
Issue date
Dec 12, 2023
Arrowhead Pharmaceuticals, Inc.
So Wong
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for modulating gene expression
Patent number
11,759,533
Issue date
Sep 19, 2023
Wisconsin Alumni Research Foundation
Aseem Ansari
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotide compositions and methods of use thereof
Patent number
11,603,532
Issue date
Mar 14, 2023
WAVE LIFE SCIENCES LTD.
Chandra Vargeese
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Interfering RNA molecules
Patent number
11,578,328
Issue date
Feb 14, 2023
Silence Therapeutics GmbH
Klaus Giese
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligomeric compounds comprising bicyclic nucleotides and uses thereof
Patent number
11,566,245
Issue date
Jan 31, 2023
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modulation of SMN2 splicing in a subject
Patent number
11,535,848
Issue date
Dec 27, 2022
Biogen MA Inc.
Frank Rigo
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Double-stranded oligonucleotide, composition and conjugate comprisi...
Patent number
11,492,620
Issue date
Nov 8, 2022
Suzhou Ribo Life Science Co., Ltd.
Hongyan Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleic acid molecule for reduction of PAPD5 and PAPD7 mRNA for tre...
Patent number
11,484,546
Issue date
Nov 1, 2022
Hoffman-La Roche Inc.
Susanne Kammler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for the specific inhibition of alpha-1 ant...
Patent number
11,459,566
Issue date
Oct 4, 2022
Dicerna Pharmaceuticals, Inc.
Bob Dale Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Treatment of thymic stromal lymphopoietin (TSLP) related diseases b...
Patent number
11,452,738
Issue date
Sep 27, 2022
EMPIRICO INC.
Omri Gottesman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Angiotensinogen (AGT) iRNA compositions and methods of use thereof
Patent number
11,419,942
Issue date
Aug 23, 2022
Alnylam Pharmaceuticals, Inc.
Donald Foster
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified RNAi agents
Patent number
11,406,716
Issue date
Aug 9, 2022
Alnylam Pharmaceuticals, Inc.
Kallanthottathil G. Rajeev
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof
Patent number
11,408,001
Issue date
Aug 9, 2022
Alnylam Pharmaceuticals, Inc.
Kevin Fitzgerald
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for the specific inhibition of alpha-1 ant...
Patent number
11,408,002
Issue date
Aug 9, 2022
Dicerna Pharmaceuticals, Inc.
Bob Dale Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
SiRNA structures for high activity and reduced off target
Patent number
11,390,871
Issue date
Jul 19, 2022
Nitto Denko Corporation
Kenjirou Minomi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
SiRNA structures for high activity and reduced off target
Patent number
11,359,202
Issue date
Jun 14, 2022
Nitto Denko Corporation
Kenjirou Minomi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions for modulating C9ORF72 expression
Patent number
11,339,393
Issue date
May 24, 2022
Ionis Pharmaceuticals, Inc.
Susan M. Freier
G01 - MEASURING TESTING
Information
Patent Grant
Methods and compositions for the specific inhibition of alpha-1 ant...
Patent number
11,312,960
Issue date
Apr 26, 2022
Dicerna Pharmaceuticals, Inc.
Bob Dale Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for the specific inhibition of alpha-1 ant...
Patent number
11,312,961
Issue date
Apr 26, 2022
Dicerna Pharmaceuticals, Inc.
Bob Dale Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for inhibition of HAO1 (hydroxyacid oxidase 1 (glycolate ox...
Patent number
11,261,447
Issue date
Mar 1, 2022
Alnylam Pharmaceuticals, Inc.
David V. Erbe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotide compounds for targeting huntingtin mRNA
Patent number
11,230,713
Issue date
Jan 25, 2022
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNAi agents and compositions for inhibiting expression of apolipopr...
Patent number
11,214,801
Issue date
Jan 4, 2022
Arrowhead Pharmaceuticals, Inc.
Zhen Li
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNAi agents for inhibiting expression of alpha-ENaC and methods of use
Patent number
11,214,802
Issue date
Jan 4, 2022
Arrowhead Pharmaceuticals, Inc.
Zhen Li
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for the specific inhibition of alpha-1 ant...
Patent number
11,208,658
Issue date
Dec 28, 2021
Dicerna Pharmaceuticals, Inc.
Bob D. Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
COMPLEMENT COMPONENT iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20240376477
Publication date
Nov 14, 2024
Alnylam Pharmaceuticals, Inc.
Anna Borodovsky
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TMPRSS6 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20240309387
Publication date
Sep 19, 2024
Alnylam Pharmaceuticals, Inc.
James Butler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
iRNA Compositions and Methods for Silencing Filamin A (FLNA)
Publication number
20240301418
Publication date
Sep 12, 2024
Alnylam Pharmaceuticals, Inc.
KIRK BROWN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNAi AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING T...
Publication number
20240279652
Publication date
Aug 22, 2024
Alnylam Pharmaceuticals, Inc.
Kallanthottathil G. Rajeev
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATMENT OF ANGPTL4 RELATED DISEASES
Publication number
20240279663
Publication date
Aug 22, 2024
EMPIRICO INC.
Omri GOTTESMAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE
Publication number
20240254486
Publication date
Aug 1, 2024
Alnylam Pharmaceuticals, Inc.
Brian Bettencourt
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Heteronucleic acid containing scpBNA or AmNA
Publication number
20240240183
Publication date
Jul 18, 2024
NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
Takanori YOKOTA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE
Publication number
20240141350
Publication date
May 2, 2024
REGULUS THERAPEUTICS INC.
Charles R. ALLERSON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ALPHA-1 ANTITRYPSIN (AAT) RNAI AGENTS, COMPOSITIONS INCLUDING AAT R...
Publication number
20240141351
Publication date
May 2, 2024
Arrowhead Pharmaceuticals, Inc.
Zhen Li
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20240132894
Publication date
Apr 25, 2024
WAVE LIFE SCIENCES LTD.
Chandra Vargeese
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNAI AGENT FOR INHIBITING HBV EXPRESSION AND USE THEREOF
Publication number
20240124879
Publication date
Apr 18, 2024
OliX Pharmaceuticals, Inc.
Sun Woo HONG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
iRNA COMPOSITIONS AND METHODS FOR SILENCING AMYLOID PRECURSOR PROTE...
Publication number
20240117349
Publication date
Apr 11, 2024
Alnylam Pharmaceuticals, Inc.
Jeffrey Zuber
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF
Publication number
20240117347
Publication date
Apr 11, 2024
WAVE LIFE SCIENCES LTD.
David Charles Donnell Butler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION
Publication number
20240100191
Publication date
Mar 28, 2024
Wisconsin Alumni Research Foundation
Aseem Ansari
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CYTARABINE-MODIFIED miRNA FOR TREATING CANCER
Publication number
20240011038
Publication date
Jan 11, 2024
Curamir Therapeutics, Inc.
Andrew Fesler
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (...
Publication number
20230357774
Publication date
Nov 9, 2023
EMPIRICO INC.
Omri GOTTESMAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Oligomeric Compounds Comprising Bicyclic Nucleotides and Uses Thereof
Publication number
20230279396
Publication date
Sep 7, 2023
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compositions and Methods for Modulation of SMN2 Splicing in a Subject
Publication number
20230183696
Publication date
Jun 15, 2023
Biogen MA Inc.
Frank RIGO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DOUBLE-STRANDED OLIGONUCLEOTIDE, COMPOSITION AND CONJUGATE COMPRISI...
Publication number
20230132756
Publication date
May 4, 2023
SUZHOU RIBO LIFE SCIENCE CO., LTD
Hongyan ZHANG
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ANGIOTENSINOGEN (AGT) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20230123192
Publication date
Apr 20, 2023
Alnylam Pharmaceuticals, Inc.
Donald Foster
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
NUCLEIC ACID MOLECULE FOR REDUCTION OF PAPD5 AND PAPD7 mRNA FOR TRE...
Publication number
20230113497
Publication date
Apr 13, 2023
Hoffman-La Roche Inc.
Susanne KAMMLER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compositions for Modulating C9ORF72 Expression
Publication number
20230112920
Publication date
Apr 13, 2023
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATMENT OF THYMIC STROMAL LYMPHOPOIETIN (TSLP) RELATED DISEASES B...
Publication number
20230074280
Publication date
Mar 9, 2023
Omri GOTTESMAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF ALPHA-1 ANT...
Publication number
20230069235
Publication date
Mar 2, 2023
Dicerna Pharmaceuticals Inc.
Bob D. BROWN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20230068339
Publication date
Mar 2, 2023
Alnylam Pharmaceuticals, Inc.
Kevin FITZGERALD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNAI AGENTS, COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING T...
Publication number
20230010288
Publication date
Jan 12, 2023
Alnylam Pharmaceuticals, Inc.
Kallanthottathil G. Rajeev
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PCSK9 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20230002772
Publication date
Jan 5, 2023
Alnylam Pharmaceuticals, Inc.
Anna Borodovsky
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF THE ALAS1 GENE
Publication number
20220403382
Publication date
Dec 22, 2022
Alnylam Pharmaceuticals, Inc.
Brian Bettencourt
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF ALPHA-1 ANT...
Publication number
20220396793
Publication date
Dec 15, 2022
Dicerna Pharmaceuticals, Inc.
Bob Dale BROWN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODIFIED RNAi AGENTS
Publication number
20220331446
Publication date
Oct 20, 2022
Alnylam Pharmaceuticals, Inc.
Kallanthottathil G. Rajeev
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...