Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:

CCHEMISTRY METALLURGY C07Organic chemistry C07DHETEROCYCLIC COMPOUNDS

C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:

C07D499/04Preparation C07D499/06by forming the ring or condensed ring systems C07D499/08Modification of a carboxyl radical directly attached in position 2 C07D499/10Modification of an amino radical directly attached in position 6 C07D499/12Acylation C07D499/14Preparation of salts C07D499/16of alkali or alkaline earth metals C07D499/18Separation Purification C07D499/20via salts with organic bases C07D499/21with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen C07D499/22Salts with organic bases Complexes with organic compounds C07D499/24with acyclic or carbocyclic compounds containing amino radicals C07D499/26with heterocyclic compounds C07D499/28with modified 2-carboxyl group C07D499/30Acid anhydride C07D499/32Esters C07D499/34Thio-acid Esters thereof C07D499/36O-esters C07D499/38S-esters C07D499/40Amides Hydrazides Azides C07D499/42Compounds with a free primary amino radical attached in position 6 C07D499/44Compounds with an amino radical acylated by carboxylic acids, attached in position 6 C07D499/46with acyclic hydrocarbon radicals or such radicals substituted by carbocyclic or heterocyclic rings, attached to the carboxamido radical C07D499/48with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen C07D499/50substituted in beta-position to the carboxamido radical C07D499/52by oxygen or sulfur atoms C07D499/54by nitrogen atoms C07D499/56by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen C07D499/58substituted in alpha-position to the carboxamido radical C07D499/60by oxygen atoms C07D499/62by sulfur atoms C07D499/64by nitrogen atoms C07D499/66with alicyclic rings as additional substituents on the carbon chain C07D499/68with aromatic rings as additional substituents on the carbon chain C07D499/70with hetero rings as additional substituents on the carbon chain C07D499/72by carbon atoms having three bonds to hetero atoms C07D499/74with carbocyclic rings directly attached to the carboxamido radical C07D499/76with hetero rings directly attached to the carboxamido radical C07D499/78Compounds with an amino radical, acylated by carbonic acid, or by nitrogen or sulfur analogues thereof, attached in position 6 C07D499/80Compounds with a nitrogen-containing hetero ring, attached with the ring nitrogen atom in position 6 C07D499/86with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen C07D499/861with a hydrocarbon radical or a substituted hydrocarbon radical, directly attached in position 6 C07D499/865with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen C07D499/87Compounds being unsubstituted in position 3 or with substituents other than only two methyl radicals attached in position 3, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen C07D499/881with a hydrogen atom or an unsubstituted hydrocarbon radical, attached in position 3 C07D499/883with a substituted hydrocarbon radical attached in position 3 C07D499/887with a hetero atom or a carbon atom having three bonds to hetero atoms with at the most one bond to halogen C07D499/893with a hetero ring or a condensed hetero ring system, directly attached in position 3 C07D499/897Compounds with substituents other than a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, directly attached in position 2 C07D499/90further condensed with carbocyclic rings or ring systems