Hybrid immunoglobulins

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C07K16/46

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CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K16/00Immunoglobulins [IGs]

Current Industry

C07K16/46Hybrid immunoglobulins

Industries

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Patents Grantslast 30 patents

Information Patent Grant
Single-chain TNF Receptor 2 agonist fusion proteins
- Patent number 12,365,712
- Issue date Jul 22, 2025
- RELINIA, INC.
- David C Foster
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Anti-CD28 x anti-PSMA antibodies
- Patent number 12,365,743
- Issue date Jul 22, 2025
- Xencor, Inc.
- John R. Desjarlais
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Heterodimeric antibodies that bind CD3 and tumor antigens
- Patent number 12,359,002
- Issue date Jul 15, 2025
- Xencor, Inc.
- Matthew Bernett
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bispecific anti-human A-beta/anti-human transferrin receptor antibo...
- Patent number 12,358,997
- Issue date Jul 15, 2025
- HOFFMANN-LA ROCHE INC.
- Harald Duerr
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Method for producing polypeptide hetero-oligomer
- Patent number 12,359,001
- Issue date Jul 15, 2025
- CHUGAI SEIYAKU KABUSHIKI KAISHA
- Tomoyuki Igawa
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
HLA binding vaccine moieties and uses thereof
- Patent number 12,358,989
- Issue date Jul 15, 2025
- University of Oslo
- Gunnveig Grodeland
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Immunoglobulin lambda light chain and uses thereof
- Patent number 12,356,967
- Issue date Jul 15, 2025
- REGENERON PHARMACEUTICALS, INC.
- Andrew J. Murphy
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Anti-CD6 antibody-growth factor complex for treating autoimmune dis...
- Patent number 12,358,998
- Issue date Jul 15, 2025
- City of Hope
- Jose Enrique Montero Casimiro
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treating neutorpenia using G-CSF protein complex
- Patent number 12,350,315
- Issue date Jul 8, 2025
- SPECTRUM PHARMACEUTICALS, INC.
- Gajanan Bhat
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-CD30 antibodies
- Patent number 12,351,639
- Issue date Jul 8, 2025
- The Medical College of Wisconsin, Inc.
- Jeffrey A. Medin
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
PD1 and/or LAG3 binders
- Patent number 12,351,630
- Issue date Jul 8, 2025
- Merck Sharp & Dohme LLC
- Edward Bowman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibodies binding to fibroblast activation protein alpha and death...
- Patent number 12,351,650
- Issue date Jul 8, 2025
- GENMAB A/S
- Bart E.C.G. De Goeij
- G01 - MEASURING TESTING
Information Patent Grant
Bispecific antibody
- Patent number 12,344,674
- Issue date Jul 1, 2025
- Mie University
- Hiroshi Shiku
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
CH3 domain variant pair inducing formation of heterodimer of heavy...
- Patent number 12,344,679
- Issue date Jul 1, 2025
- AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
- Yong Sung Kim
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
CD47-CD38 bispecific antibodies
- Patent number 12,338,292
- Issue date Jun 24, 2025
- IGI Therapeutics SA
- Laure Bouchez
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Efflux pump-cancer antigen multi-specific antibodies and compositio...
- Patent number 12,331,121
- Issue date Jun 17, 2025
- William Robert Arathoon Living Trust Dated August 29, 2016
- William Robert Arathoon
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antigen binding molecule formats
- Patent number 12,331,109
- Issue date Jun 17, 2025
- REGENERON PHARMACEUTICALS, INC.
- Tong Zhang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Protease cleavable bispecific antibodies and uses thereof
- Patent number 12,325,757
- Issue date Jun 10, 2025
- Zhejiang Shimai Pharmaceutical Co., Ltd.
- Weizao Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-TNFα/anti IL-17A natural antibody structure-like heterodimer f...
- Patent number 12,325,743
- Issue date Jun 10, 2025
- Beijing Hanmi Pharmaceutical Co., Ltd.
- Jiawang Liu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Protease cleavable bispecific antibodies and uses thereof
- Patent number 12,325,758
- Issue date Jun 10, 2025
- Zhejiang Shimai Pharmaceutical Co., Ltd.
- Weizao Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
ROR1-specific antigen binding molecules
- Patent number 12,324,837
- Issue date Jun 10, 2025
- ALMAC DISCOVERY LIMITED
- Estelle Grace McLean
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods for making antibody conjugates
- Patent number 12,324,842
- Issue date Jun 10, 2025
- The Trustees of the University of Pennsylvania
- Andrew Tsourkas
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-VEGF-anti-PD-L1 bispecific antibody, pharmaceutical compositio...
- Patent number 12,325,759
- Issue date Jun 10, 2025
- BIOTHEUS INC.
- Xiaoniu Miao
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods of treating neutorpenia using G-CSF protein complex
- Patent number 12,318,430
- Issue date Jun 3, 2025
- SPECTRUM PHARMACEUTICALS, INC.
- Gajanan Bhat
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Orthogonal mutations for heterodimerization
- Patent number 12,312,418
- Issue date May 27, 2025
- INVENRA INC.
- Jonathan Harry Davis
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Detection of anti-p53 antibodies
- Patent number 12,306,185
- Issue date May 20, 2025
- Roche Diagnostics Operations, Inc.
- Herbert Andres
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Nuclear localization signals, compositions formed therefrom, and me...
- Patent number 12,304,970
- Issue date May 20, 2025
- Yale University
- James E. Hansen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Method for controlling affinity of antibody for antigen, antibody w...
- Patent number 12,304,971
- Issue date May 20, 2025
- Sysmex Corporation
- Shingo Maeta
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Non-human animals expressing exogenous terminal deoxynucleotidyltra...
- Patent number 12,295,354
- Issue date May 13, 2025
- REGENERON PHARMACEUTICALS, INC.
- Lynn Macdonald
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions for reducing the immunogenicity of chimeri...
- Patent number 12,297,243
- Issue date May 13, 2025
- Cell Design Labs, Inc.
- Peter Emtage
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
Stabilized Formulations Containing Anti-CD20 x Anti-CD3 Bispecific...
- Publication number 20250236677
- Publication date Jul 24, 2025
- Regeneron Pharmaceuticals, Inc.
- Yuan Cheng
- C07 - ORGANIC CHEMISTRY
Information Patent Application
GENERATION OF BINDING MOLECULES
- Publication number 20250230579
- Publication date Jul 17, 2025
- Merus N.V.
- Mark THROSBY
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HETERODIMERIC HUMAN IgG1 POLYPEPTIDES WITH ISOELECTRIC POINT MODIFI...
- Publication number 20250230262
- Publication date Jul 17, 2025
- Xencor, Inc.
- Gregory L. Moore
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHODS AND AGENTS FOR THE TREATMENT OF OCULAR DISEASE
- Publication number 20250230228
- Publication date Jul 17, 2025
- Line 6 Biotechnology, Inc.
- Brian W. ZIEGELAAR
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHODS OF CONTAMINANT REMOVAL FROM PROTEIN ISOLATES
- Publication number 20250223313
- Publication date Jul 10, 2025
- Shattuck Labs, Inc.
- Taylor SCHREIBER
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BISPECIFIC ANTI-HUMAN A-BETA/HUMAN TRANSFERRIN RECEPTOR ANTIBODIES...
- Publication number 20250223372
- Publication date Jul 10, 2025
- HOFFMANN-LA ROCHE INC.
- Harald Duerr
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
VARIANT CH3 DOMAINS ENGINEERED FOR PREFERENTIAL CH3 HETERODIMERIZAT...
- Publication number 20250223379
- Publication date Jul 10, 2025
- ADIMAB, LLC
- Caitlin STEIN
- C40 - COMBINATORIAL CHEMISTRY
Information Patent Application
WNT SURROGATE MOLECULES AND USES THEREOF
- Publication number 20250223368
- Publication date Jul 10, 2025
- Surrozen Operating, Inc.
- Yang LI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MODIFIED ANTIGEN BINDINGPOLYPEPTIDE CONSTRUCTS AND USES THEREOF
- Publication number 20250215115
- Publication date Jul 3, 2025
- ZYMEWORKS BC INC.
- Mario Sanches
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NEUTRALIZING ANTIBODIES TO GP120 AND THEIR USE
- Publication number 20250215068
- Publication date Jul 3, 2025
- The U.S.A as represented by the Secretary, Department of Health and Human Ser...
- Mark Connors
- G01 - MEASURING TESTING
Information Patent Application
Use of Car and Bite Technology Coupled with an SCFV from an Antibod...
- Publication number 20250215075
- Publication date Jul 3, 2025
- Kim Leslie O'Neill
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTIGEN BINDING PROTEINS SPECIFICALLY BINDING MAGE-A
- Publication number 20250215084
- Publication date Jul 3, 2025
- Immatics Biotechnologies GmbH
- Meike HUTT
- C07 - ORGANIC CHEMISTRY
Information Patent Application
NOVEL ANTI-CD38 ANTIBODIES FOR THE TREATMENT OF CANCER
- Publication number 20250216392
- Publication date Jul 3, 2025
- sanofi-aventis U.S. LLC
- Peter U. PARK
- G01 - MEASURING TESTING
Information Patent Application
Engineered Probiotic Delivery System for Anti-SARS-COV-2 Treatment...
- Publication number 20250213666
- Publication date Jul 3, 2025
- University of Cincinnati
- Nitin S Kamble
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DIMERIC ANTIBODIES
- Publication number 20250205354
- Publication date Jun 26, 2025
- Medicovestor, Inc.
- Seah Lim
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS OF DEPLETING DISEASE CAUSING AGENTS VIA ANTIBODY TARGETED P...
- Publication number 20250206826
- Publication date Jun 26, 2025
- Dren Bio, Inc.
- Panagiotis FOTAKIS
- C07 - ORGANIC CHEMISTRY
Information Patent Application
METHOD FOR IN VIVO GENERATION OF MULTISPECIFIC ANTIBODIES FROM MONO...
- Publication number 20250206821
- Publication date Jun 26, 2025
- HOFFMANN-LA ROCHE INC.
- Ulrich Brinkmann
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DIMERIC ANTIBODIES AND THEIR METHODS OF MANUFACTURE
- Publication number 20250206847
- Publication date Jun 26, 2025
- Medicovestor, Inc.
- Seah Lim
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BISPECIFIC ANTIBODIES WITH CLEAVABLE C-TERMINAL CHARGE-PAIRED TAGS
- Publication number 20250197518
- Publication date Jun 19, 2025
- Amgen Inc.
- John K. KAWOOYA
- C07 - ORGANIC CHEMISTRY
Information Patent Application
TRISPECIFIC BINDING PROTEINS AND METHODS OF USE
- Publication number 20250197526
- Publication date Jun 19, 2025
- Harpoon Therapeutics, Inc.
- Patrick BAEUERLE
- C07 - ORGANIC CHEMISTRY
Information Patent Application
FUSION PROTEINS COMPRISING AN E2 UBIQUITIN OR UBIQUITIN-LIKE CONJUG...
- Publication number 20250197819
- Publication date Jun 19, 2025
- MEDIMMUNE LIMITED
- SANDRINE LEGG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
STABLE HETERODIMERIC ANTIBODY DESIGN WITH MUTATIONS IN THE Fc DOMAIN
- Publication number 20250197527
- Publication date Jun 19, 2025
- ZYMEWORKS BC INC.
- Thomas Spreter Von Kreudenstein
- C07 - ORGANIC CHEMISTRY
Information Patent Application
HUMANIZED CHIMERIC BOVINE ANTIBODIES AND METHODS OF USE
- Publication number 20250197525
- Publication date Jun 19, 2025
- Minotaur Therapeutics, Inc.
- Ruiqi HUANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Anti-FLT3 Antigen Binding Proteins
- Publication number 20250197510
- Publication date Jun 19, 2025
- Deutsches Krebsforschungszentrum Stiftung des Offentlichen Rechts
- Gundram Jung
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NATURAL KILLER (NK) CELL ENGAGERS BINDING TO NKp46 AND BCMA VARIANT...
- Publication number 20250197528
- Publication date Jun 19, 2025
- SANOFI
- Nicolas GOURDIN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS AND METHODS RELATED TO IL27 RECEPTOR BINDING
- Publication number 20250179198
- Publication date Jun 5, 2025
- Synthekine, Inc.
- Robert Kastelein
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NEUTRALIZING ANTIBODIES TO GP120 AND THEIR USE
- Publication number 20250179154
- Publication date Jun 5, 2025
- The U.S.A as represented by the Secretary, Department of Health and Human Ser...
- Mark Connors
- G01 - MEASURING TESTING
Information Patent Application
Anti-Abeta Antibodies
- Publication number 20250179161
- Publication date Jun 5, 2025
- OTHAIR PROTHENA LIMITED
- Michael SKOV
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTISPECIFIC ANTIGEN-BINDING PROTEINS
- Publication number 20250177523
- Publication date Jun 5, 2025
- Genentech, Inc.
- Paul CARTER
- G01 - MEASURING TESTING
Information Patent Application
HUMAN IgG Fc DOMAIN VARIANTS WITH IMPROVED EFFECTOR FUNCTION
- Publication number 20250171558
- Publication date May 29, 2025
- THE ROCKEFELLER UNIVERSITY
- Jeffrey V. Ravetch
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Hybrid immunoglobulins

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Single-chain TNF Receptor 2 agonist fusion proteins

Anti-CD28 x anti-PSMA antibodies

Heterodimeric antibodies that bind CD3 and tumor antigens

Bispecific anti-human A-beta/anti-human transferrin receptor antibo...

Method for producing polypeptide hetero-oligomer

HLA binding vaccine moieties and uses thereof

Immunoglobulin lambda light chain and uses thereof

Anti-CD6 antibody-growth factor complex for treating autoimmune dis...

Methods of treating neutorpenia using G-CSF protein complex

Anti-CD30 antibodies

PD1 and/or LAG3 binders

Antibodies binding to fibroblast activation protein alpha and death...

Bispecific antibody

CH3 domain variant pair inducing formation of heterodimer of heavy...

CD47-CD38 bispecific antibodies

Efflux pump-cancer antigen multi-specific antibodies and compositio...

Antigen binding molecule formats

Protease cleavable bispecific antibodies and uses thereof

Anti-TNFα/anti IL-17A natural antibody structure-like heterodimer f...

Protease cleavable bispecific antibodies and uses thereof

ROR1-specific antigen binding molecules

Compositions and methods for making antibody conjugates

Anti-VEGF-anti-PD-L1 bispecific antibody, pharmaceutical compositio...

Methods of treating neutorpenia using G-CSF protein complex

Orthogonal mutations for heterodimerization

Detection of anti-p53 antibodies

Nuclear localization signals, compositions formed therefrom, and me...

Method for controlling affinity of antibody for antigen, antibody w...

Non-human animals expressing exogenous terminal deoxynucleotidyltra...

Methods and compositions for reducing the immunogenicity of chimeri...

Patents Applicationslast 30 patents

Stabilized Formulations Containing Anti-CD20 x Anti-CD3 Bispecific...

GENERATION OF BINDING MOLECULES

HETERODIMERIC HUMAN IgG1 POLYPEPTIDES WITH ISOELECTRIC POINT MODIFI...

METHODS AND AGENTS FOR THE TREATMENT OF OCULAR DISEASE

METHODS OF CONTAMINANT REMOVAL FROM PROTEIN ISOLATES

BISPECIFIC ANTI-HUMAN A-BETA/HUMAN TRANSFERRIN RECEPTOR ANTIBODIES...

VARIANT CH3 DOMAINS ENGINEERED FOR PREFERENTIAL CH3 HETERODIMERIZAT...

WNT SURROGATE MOLECULES AND USES THEREOF

MODIFIED ANTIGEN BINDINGPOLYPEPTIDE CONSTRUCTS AND USES THEREOF

NEUTRALIZING ANTIBODIES TO GP120 AND THEIR USE

Use of Car and Bite Technology Coupled with an SCFV from an Antibod...

ANTIGEN BINDING PROTEINS SPECIFICALLY BINDING MAGE-A

NOVEL ANTI-CD38 ANTIBODIES FOR THE TREATMENT OF CANCER

Engineered Probiotic Delivery System for Anti-SARS-COV-2 Treatment...

DIMERIC ANTIBODIES

METHODS OF DEPLETING DISEASE CAUSING AGENTS VIA ANTIBODY TARGETED P...

METHOD FOR IN VIVO GENERATION OF MULTISPECIFIC ANTIBODIES FROM MONO...

DIMERIC ANTIBODIES AND THEIR METHODS OF MANUFACTURE

BISPECIFIC ANTIBODIES WITH CLEAVABLE C-TERMINAL CHARGE-PAIRED TAGS

TRISPECIFIC BINDING PROTEINS AND METHODS OF USE

FUSION PROTEINS COMPRISING AN E2 UBIQUITIN OR UBIQUITIN-LIKE CONJUG...

STABLE HETERODIMERIC ANTIBODY DESIGN WITH MUTATIONS IN THE Fc DOMAIN

HUMANIZED CHIMERIC BOVINE ANTIBODIES AND METHODS OF USE

Anti-FLT3 Antigen Binding Proteins

NATURAL KILLER (NK) CELL ENGAGERS BINDING TO NKp46 AND BCMA VARIANT...

COMPOSITIONS AND METHODS RELATED TO IL27 RECEPTOR BINDING

NEUTRALIZING ANTIBODIES TO GP120 AND THEIR USE

Anti-Abeta Antibodies

MULTISPECIFIC ANTIGEN-BINDING PROTEINS

HUMAN IgG Fc DOMAIN VARIANTS WITH IMPROVED EFFECTOR FUNCTION