Increased effector function due to an Fc-modification

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CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K2317/00Immunoglobulins specific feautures

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C07K2317/72Increased effector function due to an Fc-modification

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Patents Grantslast 30 patents

Information Patent Grant
Immune complex
- Patent number 12,186,385
- Issue date Jan 7, 2025
- The Rockefeller University
- Jeffrey V. Ravetch
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Humanized anti-SIRPα antibodies
- Patent number 12,180,295
- Issue date Dec 31, 2024
- Byondis B.V.
- Gijsbertus Franciscus Maria Verheijden
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bispecific molecules comprising an HIV-1 envelope targeting arm
- Patent number 12,173,051
- Issue date Dec 24, 2024
- Duke University
- Barton F. Haynes
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Polypeptide variants and uses thereof
- Patent number 12,173,076
- Issue date Dec 24, 2024
- GENMAB B.V.
- Frank Beurskens
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
EPHA2 antibodies
- Patent number 12,162,945
- Issue date Dec 10, 2024
- Immunome, Inc.
- Alexander Scholz
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Humanized mouse models of the FcRn recycling pathway
- Patent number 12,156,517
- Issue date Dec 3, 2024
- The Jackson Laboratory
- Michael V. Wiles
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Methods of using bispecific antigen-binding constructs targeting HER2
- Patent number 12,157,775
- Issue date Dec 3, 2024
- ZYMEWORKS BC INC.
- Grant Raymond Wickman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions for increasing half-life of a therapeutic agent in liv...
- Patent number 12,103,961
- Issue date Oct 1, 2024
- Invetx, Inc.
- William Brondyk
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Optimized binuclease fusions and methods
- Patent number 12,077,790
- Issue date Sep 3, 2024
- Resolve Therapeutics, LLC
- James Arthur Posada
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods comprising anti-NRP2 antibodies
- Patent number 12,065,495
- Issue date Aug 20, 2024
- Atyr Pharma, Inc.
- Luke G. Burman
- G01 - MEASURING TESTING
Information Patent Grant
Therapeutic binding molecules
- Patent number 12,049,506
- Issue date Jul 30, 2024
- Josquin Nys
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
C1q and HMGB1 fusion proteins and uses thereof
- Patent number 12,037,419
- Issue date Jul 16, 2024
- The Feinstein Institutes for Medical Research
- Betty A. Diamond
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Variant IgG Fc polypeptides and uses thereof
- Patent number 12,030,945
- Issue date Jul 9, 2024
- Seismic Therapeutic, Inc.
- Yen-Lin Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Anti-SIRPalpha antibody
- Patent number 12,024,566
- Issue date Jul 2, 2024
- National University Corporation Kobe University
- Takashi Matozaki
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibodies specific for human complement C5A receptor (C5AR)
- Patent number 12,018,072
- Issue date Jun 25, 2024
- Morphosys AG
- Julia Neugebauer
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody variants
- Patent number 11,999,781
- Issue date Jun 4, 2024
- TILLOTTS PHARMA AG
- Esther Maria Furrer
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibody therapeutics that bind CD38
- Patent number 11,999,792
- Issue date Jun 4, 2024
- Vivasor, Inc.
- Heyue Zhou
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Anti-PSMA antibodies and uses thereof
- Patent number 11,987,641
- Issue date May 21, 2024
- Janssen Biotech, Inc.
- Shalom Goldberg
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Neutralizing antibodies to ebola virus glycoprotein and their use
- Patent number 11,976,109
- Issue date May 7, 2024
- The United States of America, as represented by the Secretary, Department of...
- Nancy Sullivan
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
scFv-Fc dimers that bind transforming growth factor-β1 with high af...
- Patent number 11,976,112
- Issue date May 7, 2024
- Genzyme Coporation
- Huawei Qiu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Biopharmaceutical compositions comprising nucleic acids encoding IL...
- Patent number 11,976,113
- Issue date May 7, 2024
- GlaxoSmithKline Intellectual Property Development Limited
- Steven Grant
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Anti-family with sequence similarity 19, member A5 antibodies and m...
- Patent number 11,970,532
- Issue date Apr 30, 2024
- Neuracle Science Co., Ltd.
- Bongcheol Kim
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-CD20 antibody
- Patent number 11,970,541
- Issue date Apr 30, 2024
- Beijing Mabworks Biotech Co. Ltd.
- Feng Li
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Engineered antibody Fc variants for enhanced serum half life
- Patent number 11,958,904
- Issue date Apr 16, 2024
- Research Development Foundation
- George Georgiou
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Bispecific PD-1 and TIGIT binding proteins and uses thereof
- Patent number 11,939,382
- Issue date Mar 26, 2024
- MedImmune, LLC
- Yariv Mazor
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Masked chimeric antigen receptor specific to tyrosine-protein kinas...
- Patent number 11,926,676
- Issue date Mar 12, 2024
- CRISPR THERAPEUTICS AG
- Jason Sagert
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Neutralizing anti-influenza binding molecules and uses thereof
- Patent number 11,926,657
- Issue date Mar 12, 2024
- MedImmune, LLC
- Nicole Kallewaard-Lelay
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Highly potent antibodies binding to death receptor 5
- Patent number 11,891,446
- Issue date Feb 6, 2024
- Galaxy Biotech, LLC
- Kyung Jin Kim
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Polynucleotides encoding monoclonal antibodies binding to human pit...
- Patent number 11,891,435
- Issue date Feb 6, 2024
- Amgen Inc.
- Neeraj Jagdish Agrawal
- G01 - MEASURING TESTING
Information Patent Grant
VISTA antigen-binding molecules
- Patent number 11,873,346
- Issue date Jan 16, 2024
- Hummingbird Bioscience Pte. Ltd.
- Jerome Douglas Boyd-Kirkup
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
HER3 ANTIGEN-BINDING MOLECULES
- Publication number 20250019461
- Publication date Jan 16, 2025
- Hummingbird Bioscience Pte. Ltd.
- Jerome Douglas Boyd-Kirkup
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIOSYNTHETIC MONOVALENT BINDING MOLECULES WITH ENHANCED EFFECTOR FU...
- Publication number 20250011454
- Publication date Jan 9, 2025
- JANSSEN BIOTECH, INC.
- Adam ZWOLAK
- C07 - ORGANIC CHEMISTRY
Information Patent Application
OPTIMIZED BINUCLEASE FUSIONS AND METHODS
- Publication number 20250002884
- Publication date Jan 2, 2025
- Resolve Therapeutics, LLC
- James Arthur Posada
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
IGA FC AND IGG FC TANDEM PROTEIN CONSTRUCTS
- Publication number 20250002602
- Publication date Jan 2, 2025
- OSLO UNIVERSITETSSYKEHUS HF
- Jan Terje ANDERSEN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
OPTIMIZED BINUCLEASE FUSIONS AND METHODS
- Publication number 20250002885
- Publication date Jan 2, 2025
- Resolve Therapeutics, LLC
- James Arthur Posada
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIOPHARMACEUTICAL COMPOSITIONS AND RELATED METHODS
- Publication number 20240417456
- Publication date Dec 19, 2024
- GlaxoSmithKline Intellectual Property Development Limited
- Steven GRANT
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Antibodies Reactive with B7-H3, Immunologically Active Fragments Th...
- Publication number 20240409661
- Publication date Dec 12, 2024
- MacroGenics, Inc.
- Leslie S. Johnson
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIBODIES TARGETING C5AR
- Publication number 20240400657
- Publication date Dec 5, 2024
- Morphosys AG
- Julia Neugebauer
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMBINATION OF ANTI-CD40 ANTIBODY AND IL-15 FOR TREATING CANCER
- Publication number 20240400706
- Publication date Dec 5, 2024
- THE ROCKEFELLER UNIVERSITY
- Jeffrey V. Ravetch
- C07 - ORGANIC CHEMISTRY
Information Patent Application
IL1RAP ANTIBODIES AND USES THEREOF
- Publication number 20240392013
- Publication date Nov 28, 2024
- STELEXIS THERAPEUTICS, LLC
- Patrick James DOYLE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS OF TREATING CANCER USING PD-1 AXIS BINDING ANTAGONISTS AND...
- Publication number 20240390488
- Publication date Nov 28, 2024
- Genentech, Inc.
- Melissa JUNTTILA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TUMOR-SPECIFIC PAYLOAD DELIVERY AND IMMUNE ACTIVATION USING A HUMAN...
- Publication number 20240374748
- Publication date Nov 14, 2024
- The Regents of the University of California
- Bin Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTI-FAMILY WITH SEQUENCE SIMILARITY 19, MEMBER A5 ANTIBODIES AND M...
- Publication number 20240360209
- Publication date Oct 31, 2024
- NEURACLE SCIENCE CO., LTD.
- Bongcheol KIM
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MASKED CHIMERIC ANTIGEN RECEPTOR SPECIFIC TO TYROSINE-PROTEIN KINAS...
- Publication number 20240352151
- Publication date Oct 24, 2024
- CRISPR Therapeutics AG
- Jason Sagert
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Bispecific Asymmetric Heterodimers Comprising Anti-CD3 Constructs
- Publication number 20240343802
- Publication date Oct 17, 2024
- ZYMEWORKS BC INC.
- Gordon Yiu Kon Ng
- C07 - ORGANIC CHEMISTRY
Information Patent Application
SCFV-FC DIMERS THAT BIND TRANSFORMING GROWTH FACTOR-BETA1 WITH HIGH...
- Publication number 20240343790
- Publication date Oct 17, 2024
- Genzyme Corporation
- Huawei Qiu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTIBODY VARIANTS
- Publication number 20240343793
- Publication date Oct 17, 2024
- Tillotts Pharma AG
- Esther Maria FURRER
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTIBODIES TO CD40
- Publication number 20240336695
- Publication date Oct 10, 2024
- Bristol-Myers Squibb Company
- Bryan C. BARNHART
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIBODIES AGAINST INFLUENZA A VIRUSES
- Publication number 20240317841
- Publication date Sep 26, 2024
- Vir Biotechnology, Inc.
- Davide CORTI
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIBODIES AND METHODS FOR THE DETECTION OF CELL DEATH
- Publication number 20240310386
- Publication date Sep 19, 2024
- PHARMA CINQ, LLC
- Jeffrey Allan MILLER
- G01 - MEASURING TESTING
Information Patent Application
ANTIGEN BINDING MOLECULES WITH INCREASED FC RECEPTOR BINDING AFFINI...
- Publication number 20240301079
- Publication date Sep 12, 2024
- Roche Glycart AG
- Pablo UMAÑA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTI-SIRPa ANTIBODY
- Publication number 20240294660
- Publication date Sep 5, 2024
- National University Corporation KOBE University
- Takashi Matozaki
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ARMED NK CELLS FOR UNIVERSAL CELL THERAPY
- Publication number 20240293455
- Publication date Sep 5, 2024
- UNIVERSITE DE MONTPELLIER
- Martin Villalba
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
HETERODIMERIC IGA FC CONSTRUCTS AND METHODS OF USE THEREOF
- Publication number 20240294667
- Publication date Sep 5, 2024
- ZYMEWORKS BC INC.
- Eric Escobar-Cabrera
- C07 - ORGANIC CHEMISTRY
Information Patent Application
HETERODIMERIC Fc VARIANTS SELECTIVE FOR Fc GAMMA RIIB
- Publication number 20240294646
- Publication date Sep 5, 2024
- ZYMEWORKS BC INC.
- ERIC ESCOBAR-CABRERA
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BISPECIFIC PD-1 AND TIGIT BINDING PROTEINS AND USES THEREOF
- Publication number 20240287183
- Publication date Aug 29, 2024
- Medimmune, LLC
- Yariv MAZOR
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIBODY COCKTAIL FOR TREATMENT OF EBOLAVIRUS INFECTIONS
- Publication number 20240287160
- Publication date Aug 29, 2024
- Vanderbilt University
- James E. CROWE
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIGEN-BINDING MOLECULE PROMOTING DISAPPEARANCE OF ANTIGENS HAVING...
- Publication number 20240279325
- Publication date Aug 22, 2024
- Chugai SeiYaku Kabushiki Kaisha
- Tomoyuki Igawa
- C07 - ORGANIC CHEMISTRY
Information Patent Application
USING FUCOSIDASE TO CONTROL AFUCOSYLATION LEVEL OF GLYCOSYLATED PRO...
- Publication number 20240279704
- Publication date Aug 22, 2024
- Amgen Inc.
- Namratha SUBHASH
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ENGINEERED ANTIBODY FC VARIANTS FOR ENHANCED SERUM HALF LIFE
- Publication number 20240270852
- Publication date Aug 15, 2024
- Research Development Foundation
- George GEORGIOU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Increased effector function due to an Fc-modification

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Immune complex

Humanized anti-SIRPα antibodies

Bispecific molecules comprising an HIV-1 envelope targeting arm

Polypeptide variants and uses thereof

EPHA2 antibodies

Humanized mouse models of the FcRn recycling pathway

Methods of using bispecific antigen-binding constructs targeting HER2

Compositions for increasing half-life of a therapeutic agent in liv...

Optimized binuclease fusions and methods

Compositions and methods comprising anti-NRP2 antibodies

Therapeutic binding molecules

C1q and HMGB1 fusion proteins and uses thereof

Variant IgG Fc polypeptides and uses thereof

Anti-SIRPalpha antibody

Antibodies specific for human complement C5A receptor (C5AR)

Antibody variants

Antibody therapeutics that bind CD38

Anti-PSMA antibodies and uses thereof

Neutralizing antibodies to ebola virus glycoprotein and their use

scFv-Fc dimers that bind transforming growth factor-β1 with high af...

Biopharmaceutical compositions comprising nucleic acids encoding IL...

Anti-family with sequence similarity 19, member A5 antibodies and m...

Anti-CD20 antibody

Engineered antibody Fc variants for enhanced serum half life

Bispecific PD-1 and TIGIT binding proteins and uses thereof

Masked chimeric antigen receptor specific to tyrosine-protein kinas...

Neutralizing anti-influenza binding molecules and uses thereof

Highly potent antibodies binding to death receptor 5

Polynucleotides encoding monoclonal antibodies binding to human pit...

VISTA antigen-binding molecules

Patents Applicationslast 30 patents

HER3 ANTIGEN-BINDING MOLECULES

BIOSYNTHETIC MONOVALENT BINDING MOLECULES WITH ENHANCED EFFECTOR FU...

OPTIMIZED BINUCLEASE FUSIONS AND METHODS

IGA FC AND IGG FC TANDEM PROTEIN CONSTRUCTS

OPTIMIZED BINUCLEASE FUSIONS AND METHODS

BIOPHARMACEUTICAL COMPOSITIONS AND RELATED METHODS

Antibodies Reactive with B7-H3, Immunologically Active Fragments Th...

ANTIBODIES TARGETING C5AR

COMBINATION OF ANTI-CD40 ANTIBODY AND IL-15 FOR TREATING CANCER

IL1RAP ANTIBODIES AND USES THEREOF

METHODS OF TREATING CANCER USING PD-1 AXIS BINDING ANTAGONISTS AND...

TUMOR-SPECIFIC PAYLOAD DELIVERY AND IMMUNE ACTIVATION USING A HUMAN...

ANTI-FAMILY WITH SEQUENCE SIMILARITY 19, MEMBER A5 ANTIBODIES AND M...

MASKED CHIMERIC ANTIGEN RECEPTOR SPECIFIC TO TYROSINE-PROTEIN KINAS...

Bispecific Asymmetric Heterodimers Comprising Anti-CD3 Constructs

SCFV-FC DIMERS THAT BIND TRANSFORMING GROWTH FACTOR-BETA1 WITH HIGH...

ANTIBODY VARIANTS

ANTIBODIES TO CD40

ANTIBODIES AGAINST INFLUENZA A VIRUSES

ANTIBODIES AND METHODS FOR THE DETECTION OF CELL DEATH

ANTIGEN BINDING MOLECULES WITH INCREASED FC RECEPTOR BINDING AFFINI...

ANTI-SIRPa ANTIBODY

ARMED NK CELLS FOR UNIVERSAL CELL THERAPY

HETERODIMERIC IGA FC CONSTRUCTS AND METHODS OF USE THEREOF

HETERODIMERIC Fc VARIANTS SELECTIVE FOR Fc GAMMA RIIB

BISPECIFIC PD-1 AND TIGIT BINDING PROTEINS AND USES THEREOF

ANTIBODY COCKTAIL FOR TREATMENT OF EBOLAVIRUS INFECTIONS

ANTIGEN-BINDING MOLECULE PROMOTING DISAPPEARANCE OF ANTIGENS HAVING...

USING FUCOSIDASE TO CONTROL AFUCOSYLATION LEVEL OF GLYCOSYLATED PRO...

ENGINEERED ANTIBODY FC VARIANTS FOR ENHANCED SERUM HALF LIFE