Increased effector function due to an Fc-modification

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CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K2317/00Immunoglobulins specific feautures

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C07K2317/72Increased effector function due to an Fc-modification

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Patents Grantslast 30 patents

Information Patent Grant
Ebola virus antibodies and binding agents derived therefrom
- Patent number 12,329,992
- Issue date Jun 17, 2025
- Emory University
- Rafi Ahmed
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-TNFα/anti IL-17A natural antibody structure-like heterodimer f...
- Patent number 12,325,743
- Issue date Jun 10, 2025
- Beijing Hanmi Pharmaceutical Co., Ltd.
- Jiawang Liu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Mesothelin and CD137 binding molecules
- Patent number 12,319,739
- Issue date Jun 3, 2025
- invoX Pharma Limited
- Jose Munoz-Olaya
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Engineered immunoglobulin heavy chain-light chain pairs and uses th...
- Patent number 12,304,945
- Issue date May 20, 2025
- ZYMEWORKS BC INC.
- Adam Louis Corper
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Fc variant with enhanced affinity to Fc receptors and improved ther...
- Patent number 12,297,273
- Issue date May 13, 2025
- Sanofi
- Alessandro Masiero
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-CD37 antibodies and anti-CD20 antibodies, compositions and met...
- Patent number 12,275,797
- Issue date Apr 15, 2025
- GENMAB HOLDING B.V.
- Simone Oostindie
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Neutralizing antibodies to Plasmodium falciparum circumsporozoite p...
- Patent number 12,269,872
- Issue date Apr 8, 2025
- The United States of America, as represented by the Secretary, Department of...
- Robert Seder
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibodies binding CTLA-4 and uses thereof
- Patent number 12,240,905
- Issue date Mar 4, 2025
- HARBOUR BIOMED (SHANGHAI) CO., LTD.
- Xin Gan
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-CHIKV antibodies and uses thereof
- Patent number 12,227,560
- Issue date Feb 18, 2025
- Sanofi
- Kara Carter
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody variants
- Patent number 12,215,146
- Issue date Feb 4, 2025
- TILLOTTS PHARMA AG
- Esther Maria Furrer
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Fc variants with altered binding to FcRn
- Patent number 12,215,165
- Issue date Feb 4, 2025
- Xencor, Inc.
- Aaron Keith Chamberlain
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Immune complex
- Patent number 12,186,385
- Issue date Jan 7, 2025
- The Rockefeller University
- Jeffrey V. Ravetch
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Humanized anti-SIRPα antibodies
- Patent number 12,180,295
- Issue date Dec 31, 2024
- Byondis B.V.
- Gijsbertus Franciscus Maria Verheijden
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Bispecific molecules comprising an HIV-1 envelope targeting arm
- Patent number 12,173,051
- Issue date Dec 24, 2024
- Duke University
- Barton F. Haynes
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Polypeptide variants and uses thereof
- Patent number 12,173,076
- Issue date Dec 24, 2024
- GENMAB B.V.
- Frank Beurskens
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
EPHA2 antibodies
- Patent number 12,162,945
- Issue date Dec 10, 2024
- Immunome, Inc.
- Alexander Scholz
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Humanized mouse models of the FcRn recycling pathway
- Patent number 12,156,517
- Issue date Dec 3, 2024
- The Jackson Laboratory
- Michael V. Wiles
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Methods of using bispecific antigen-binding constructs targeting HER2
- Patent number 12,157,775
- Issue date Dec 3, 2024
- ZYMEWORKS BC INC.
- Grant Raymond Wickman
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions for increasing half-life of a therapeutic agent in liv...
- Patent number 12,103,961
- Issue date Oct 1, 2024
- Invetx, Inc.
- William Brondyk
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Optimized binuclease fusions and methods
- Patent number 12,077,790
- Issue date Sep 3, 2024
- Resolve Therapeutics, LLC
- James Arthur Posada
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Compositions and methods comprising anti-NRP2 antibodies
- Patent number 12,065,495
- Issue date Aug 20, 2024
- Atyr Pharma, Inc.
- Luke G. Burman
- G01 - MEASURING TESTING
Information Patent Grant
Therapeutic binding molecules
- Patent number 12,049,506
- Issue date Jul 30, 2024
- Josquin Nys
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
C1q and HMGB1 fusion proteins and uses thereof
- Patent number 12,037,419
- Issue date Jul 16, 2024
- The Feinstein Institutes for Medical Research
- Betty A. Diamond
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Variant IgG Fc polypeptides and uses thereof
- Patent number 12,030,945
- Issue date Jul 9, 2024
- Seismic Therapeutic, Inc.
- Yen-Lin Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Anti-SIRPalpha antibody
- Patent number 12,024,566
- Issue date Jul 2, 2024
- National University Corporation Kobe University
- Takashi Matozaki
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibodies specific for human complement C5A receptor (C5AR)
- Patent number 12,018,072
- Issue date Jun 25, 2024
- Morphosys AG
- Julia Neugebauer
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibody variants
- Patent number 11,999,781
- Issue date Jun 4, 2024
- TILLOTTS PHARMA AG
- Esther Maria Furrer
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Antibody therapeutics that bind CD38
- Patent number 11,999,792
- Issue date Jun 4, 2024
- Vivasor, Inc.
- Heyue Zhou
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Anti-PSMA antibodies and uses thereof
- Patent number 11,987,641
- Issue date May 21, 2024
- Janssen Biotech, Inc.
- Shalom Goldberg
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Neutralizing antibodies to ebola virus glycoprotein and their use
- Patent number 11,976,109
- Issue date May 7, 2024
- The United States of America, as represented by the Secretary, Department of...
- Nancy Sullivan
- C07 - ORGANIC CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
ENHANCING ANTI-CANCER ACTIVITY OF IMMUNOMODULATORY FC FUSION PROTEINS
- Publication number 20250236650
- Publication date Jul 24, 2025
- Bristol-Myers Squibb Company
- John J. ENGELHARDT
- C07 - ORGANIC CHEMISTRY
Information Patent Application
HUMAN FC VARIANTS HAVING IMPROVED FCGRIIA BINDING SELECTIVITY
- Publication number 20250230257
- Publication date Jul 17, 2025
- Korea University Research and Business Foundation
- Sang Taek JUNG
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMBINATION THERAPY FOR THE TREATMENT OF CANCER
- Publication number 20250215088
- Publication date Jul 3, 2025
- TERSESA THERAPEUTICS LLC
- Jon Marc Wigginton
- C07 - ORGANIC CHEMISTRY
Information Patent Application
DEVELOPMENT AND USE OF NOVEL IMMUNOMODULATOR
- Publication number 20250215097
- Publication date Jul 3, 2025
- BEIJING TIANNUOJIANCHENG PHARMA TECH CO., LTD.
- Li HUANG
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOSITIONS FOR INCREASING HALF-LIFE OF A THERAPEUTIC AGENT IN LIV...
- Publication number 20250197478
- Publication date Jun 19, 2025
- Invetx, Inc.
- William BRONDYK
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BISPECIFIC ANTIBODIES TO HIV-1 ENV AND THEIR USE
- Publication number 20250197482
- Publication date Jun 19, 2025
- The United States of America, as represented by the Secretary, Department of...
- Peter Kwong
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
MULTISPECIFIC ANTIBODIES AND USES THEREOF
- Publication number 20250188181
- Publication date Jun 12, 2025
- Janssen Pharmaceutica N.V.
- Sanjaya SINGH
- C07 - ORGANIC CHEMISTRY
Information Patent Application
GLYCOSYLATED FC VARIANTS WITH IMPROVED SELECTIVE BINDING AFFINITY T...
- Publication number 20250188185
- Publication date Jun 12, 2025
- Korea University Research and Business Foundation
- Sang-Taek JUNG
- C07 - ORGANIC CHEMISTRY
Information Patent Application
Fc DOMAIN VARIANTS WITH ENHANCED Fc RECEPTOR BINDING
- Publication number 20250154262
- Publication date May 15, 2025
- Ablynx N.V.
- Julie A. JAWORSKI
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTI-C5 ANTIBODIES HAVING IMPROVED PHARMACOKINETICS
- Publication number 20250145698
- Publication date May 8, 2025
- Alexion Pharmaceuticals, Inc.
- Bruce A. ANDRIEN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTI-HER2 ANTIBODIES AND METHODS OF USE THEREOF
- Publication number 20250136713
- Publication date May 1, 2025
- Denali Therapeutics Inc.
- Abira BANDYOPADHYAY
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
CYTOTOXICITY TARGETING CHIMERAS
- Publication number 20250136722
- Publication date May 1, 2025
- GlaxoSmithKline Intellectual Property Development Limited
- Peiling CHEN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ANTIBODY VARIANTS
- Publication number 20250122275
- Publication date Apr 17, 2025
- Tillotts Pharma AG
- Esther Maria FURRER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions
- Publication number 20250114440
- Publication date Apr 10, 2025
- Xencor, Inc.
- John Desjarlais
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
TAU THERAPY
- Publication number 20250101089
- Publication date Mar 27, 2025
- CAMBRIDGE ENTERPRISE LIMITED
- William Alexander MCEWAN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMBINATION THERAPY OF ANTI-TYRP1/ANTI-CD3 BISPECIFIC ANTIBODIES AN...
- Publication number 20250101132
- Publication date Mar 27, 2025
- HOFFMANN-LA ROCHE INC.
- Christian Klein
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS OF USING BISPECIFIC ANTIGEN-BINDING CONSTRUCTS TARGETING HER2
- Publication number 20250084184
- Publication date Mar 13, 2025
- ZYMEWORKS BC INC.
- Grant Raymond Wickman
- C07 - ORGANIC CHEMISTRY
Information Patent Application
THERAPEUTIC BINDING MOLECULES
- Publication number 20250084174
- Publication date Mar 13, 2025
- MEDIMMUNE LIMITED
- Josquin NYS
- G01 - MEASURING TESTING
Information Patent Application
VARIANT IgG FC POLYPEPTIDES AND USES THEREOF
- Publication number 20250074984
- Publication date Mar 6, 2025
- Seismic Therapeutic, Inc.
- Yen-Lin Chen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOSITIONS AND METHODS COMPRISING ANTI-NRP2 ANTIBODIES
- Publication number 20250074990
- Publication date Mar 6, 2025
- aTyr Pharma, Inc.
- Luke BURMAN
- G01 - MEASURING TESTING
Information Patent Application
EPHA2 ANTIBODIES
- Publication number 20250051464
- Publication date Feb 13, 2025
- Immunome, Inc.
- Alexander Scholz
- C07 - ORGANIC CHEMISTRY
Information Patent Application
CYTOTOXICITY TARGETING CHIMERAS FOR CXCR3-EXPRESSING CELLS
- Publication number 20250051479
- Publication date Feb 13, 2025
- GlaxoSmithKline Intellectual Property Development Limited
- Brandon James Turunen
- C07 - ORGANIC CHEMISTRY
Information Patent Application
HUMANIZED MOUSE MODELS OF THE FCRN RECYCLING PATHWAY
- Publication number 20250049007
- Publication date Feb 13, 2025
- The Jackson Laboratory
- Michael V. Wiles
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
FC POLYPEPTIDE HAVING ALTERED GLYCOSYLATION MODIFICATION
- Publication number 20250043026
- Publication date Feb 6, 2025
- SHANGHAI BAO PHARMACEUTICALS CO., LTD.
- Yanjun LIU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
COMPOSITIONS AND METHODS OF USE FOR THERAPEUTIC ANTIBODIES
- Publication number 20250034270
- Publication date Jan 30, 2025
- Novartis AG
- Christoph HUESSER
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
HER3 ANTIGEN-BINDING MOLECULES
- Publication number 20250019461
- Publication date Jan 16, 2025
- Hummingbird Bioscience Pte. Ltd.
- Jerome Douglas Boyd-Kirkup
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
BIOSYNTHETIC MONOVALENT BINDING MOLECULES WITH ENHANCED EFFECTOR FU...
- Publication number 20250011454
- Publication date Jan 9, 2025
- JANSSEN BIOTECH, INC.
- Adam ZWOLAK
- C07 - ORGANIC CHEMISTRY
Information Patent Application
OPTIMIZED BINUCLEASE FUSIONS AND METHODS
- Publication number 20250002884
- Publication date Jan 2, 2025
- Resolve Therapeutics, LLC
- James Arthur Posada
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
IGA FC AND IGG FC TANDEM PROTEIN CONSTRUCTS
- Publication number 20250002602
- Publication date Jan 2, 2025
- OSLO UNIVERSITETSSYKEHUS HF
- Jan Terje ANDERSEN
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
OPTIMIZED BINUCLEASE FUSIONS AND METHODS
- Publication number 20250002885
- Publication date Jan 2, 2025
- Resolve Therapeutics, LLC
- James Arthur Posada
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Increased effector function due to an Fc-modification

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Ebola virus antibodies and binding agents derived therefrom

Anti-TNFα/anti IL-17A natural antibody structure-like heterodimer f...

Mesothelin and CD137 binding molecules

Engineered immunoglobulin heavy chain-light chain pairs and uses th...

Fc variant with enhanced affinity to Fc receptors and improved ther...

Anti-CD37 antibodies and anti-CD20 antibodies, compositions and met...

Neutralizing antibodies to Plasmodium falciparum circumsporozoite p...

Antibodies binding CTLA-4 and uses thereof

Anti-CHIKV antibodies and uses thereof

Antibody variants

Fc variants with altered binding to FcRn

Immune complex

Humanized anti-SIRPα antibodies

Bispecific molecules comprising an HIV-1 envelope targeting arm

Polypeptide variants and uses thereof

EPHA2 antibodies

Humanized mouse models of the FcRn recycling pathway

Methods of using bispecific antigen-binding constructs targeting HER2

Compositions for increasing half-life of a therapeutic agent in liv...

Optimized binuclease fusions and methods

Compositions and methods comprising anti-NRP2 antibodies

Therapeutic binding molecules

C1q and HMGB1 fusion proteins and uses thereof

Variant IgG Fc polypeptides and uses thereof

Anti-SIRPalpha antibody

Antibodies specific for human complement C5A receptor (C5AR)

Antibody variants

Antibody therapeutics that bind CD38

Anti-PSMA antibodies and uses thereof

Neutralizing antibodies to ebola virus glycoprotein and their use

Patents Applicationslast 30 patents

ENHANCING ANTI-CANCER ACTIVITY OF IMMUNOMODULATORY FC FUSION PROTEINS

HUMAN FC VARIANTS HAVING IMPROVED FCGRIIA BINDING SELECTIVITY

COMBINATION THERAPY FOR THE TREATMENT OF CANCER

DEVELOPMENT AND USE OF NOVEL IMMUNOMODULATOR

COMPOSITIONS FOR INCREASING HALF-LIFE OF A THERAPEUTIC AGENT IN LIV...

BISPECIFIC ANTIBODIES TO HIV-1 ENV AND THEIR USE

MULTISPECIFIC ANTIBODIES AND USES THEREOF

GLYCOSYLATED FC VARIANTS WITH IMPROVED SELECTIVE BINDING AFFINITY T...

Fc DOMAIN VARIANTS WITH ENHANCED Fc RECEPTOR BINDING

ANTI-C5 ANTIBODIES HAVING IMPROVED PHARMACOKINETICS

ANTI-HER2 ANTIBODIES AND METHODS OF USE THEREOF

CYTOTOXICITY TARGETING CHIMERAS

ANTIBODY VARIANTS

Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions

TAU THERAPY

COMBINATION THERAPY OF ANTI-TYRP1/ANTI-CD3 BISPECIFIC ANTIBODIES AN...

METHODS OF USING BISPECIFIC ANTIGEN-BINDING CONSTRUCTS TARGETING HER2

THERAPEUTIC BINDING MOLECULES

VARIANT IgG FC POLYPEPTIDES AND USES THEREOF

COMPOSITIONS AND METHODS COMPRISING ANTI-NRP2 ANTIBODIES

EPHA2 ANTIBODIES

CYTOTOXICITY TARGETING CHIMERAS FOR CXCR3-EXPRESSING CELLS

HUMANIZED MOUSE MODELS OF THE FCRN RECYCLING PATHWAY

FC POLYPEPTIDE HAVING ALTERED GLYCOSYLATION MODIFICATION

COMPOSITIONS AND METHODS OF USE FOR THERAPEUTIC ANTIBODIES

HER3 ANTIGEN-BINDING MOLECULES

BIOSYNTHETIC MONOVALENT BINDING MOLECULES WITH ENHANCED EFFECTOR FU...

OPTIMIZED BINUCLEASE FUSIONS AND METHODS

IGA FC AND IGG FC TANDEM PROTEIN CONSTRUCTS

OPTIMIZED BINUCLEASE FUSIONS AND METHODS