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Manipulation of the nucleic acid to modify its expression pattern
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A61K48/0066
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HUMAN NECESSITIES
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PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases Gene therapy
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A61K48/0066
Manipulation of the nucleic acid to modify its expression pattern
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Patents Grants
last 30 patents
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Patent Grant
Guide RNA that targets a mutant human guanylate cyclase 2A allele
Patent number
12,168,062
Issue date
Dec 17, 2024
EMENDOBIO INC.
Lior Izhar
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Chimeric protein and related genic transfer technology
Patent number
12,138,319
Issue date
Nov 12, 2024
Lucio Pastore
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Development of optimized recombinant expression construct
Patent number
12,134,776
Issue date
Nov 5, 2024
G&P BIOSCIENCE CO., LTD.
Seong Hyun Ho
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Immunostimulating vector system
Patent number
12,133,898
Issue date
Nov 5, 2024
Provecs Medical GmbH
Frank Schnieders
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Coronavirus vaccine
Patent number
12,133,899
Issue date
Nov 5, 2024
BIONTECH SE
Ugur Sahin
B82 - NANO-TECHNOLOGY
Information
Patent Grant
Polynucleotides encoding JAGGED1 for the treatment of Alagille synd...
Patent number
12,128,113
Issue date
Oct 29, 2024
ModernaTX, Inc.
Kerry Benenato
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Materials and methods for treatment of usher syndrome type 2A and/o...
Patent number
12,122,998
Issue date
Oct 22, 2024
CRISPR THERAPEUTICS AG
Mariacarmela Allocca
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Base editing of ANGPTL3 and methods of using same for treatment of...
Patent number
12,115,230
Issue date
Oct 15, 2024
Verve Therapeutics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Polynucleotides containing a stabilizing tail region
Patent number
12,109,274
Issue date
Oct 8, 2024
ModernaTX, Inc.
Gabor Butora
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleic acid comprising or coding for a histone stem-loop and a pol...
Patent number
12,109,275
Issue date
Oct 8, 2024
CureVac SE
Andreas Thess
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Adeno-associated virus vectors for treatment of Rett syndrome
Patent number
12,104,163
Issue date
Oct 1, 2024
Sarepta Therapeutics, Inc.
Colin O'Banion
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for treating viral infections targeting TRIM7
Patent number
12,104,181
Issue date
Oct 1, 2024
The Board of Regents of the University of Texas System
John W. Schoggins
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Tail-conjugated RNAs
Patent number
12,083,189
Issue date
Sep 10, 2024
TIBA BIOTECH, LLC
Jasdave S Chahal
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Vectors for the treatment of Friedreich's ataxia
Patent number
12,084,673
Issue date
Sep 10, 2024
FUNDACIÓ INSTITUT D'INVESTIGACIÓ EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL
Antoni Matilla Dueñas
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Adeno-associated virus compositions for restoring PAH gene function...
Patent number
12,076,420
Issue date
Sep 3, 2024
HOMOLOGY MEDICINES, INC.
Jason Boke Wright
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Splice-switching oligonucleotides and methods of use
Patent number
12,071,626
Issue date
Aug 27, 2024
Duke University
Jennifer Freedman
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleic acid-polypeptide compositions and methods of inducing exon...
Patent number
12,064,483
Issue date
Aug 20, 2024
AVIDITY BIOSCIENCES, INC.
Arthur A. Levin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Adeno-associated virus compositions for PAH gene transfer and metho...
Patent number
12,064,486
Issue date
Aug 20, 2024
HOMOLOGY MEDICINES, INC.
Albert Barnes Seymour
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method for treatment of a leukocyte related disease by delivery of...
Patent number
12,065,664
Issue date
Aug 20, 2024
Ramot at Tel Aviv University Ltd.
Dan Peer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Application of lentiviral vector EF1α promoter for optimising ABCD1...
Patent number
12,065,662
Issue date
Aug 20, 2024
Chengdu Youwa Biotechnology Co., Ltd.
Ran Tao
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Gene therapy
Patent number
12,059,478
Issue date
Aug 13, 2024
Ospedale San Raffaele S.r.l.
Anna Christina Kajaste-Rudnitski
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Making and using in vitro-synthesized ssRNA for introducing into ma...
Patent number
12,059,479
Issue date
Aug 13, 2024
Cellscript, LLC
Judith Meis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Treating metastatic cancer and model systems for metastatic disease
Patent number
12,059,480
Issue date
Aug 13, 2024
Memorial Sloan Kettering Cancer Center
Karuna Ganesh
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Stabilization of poly(A) sequence encoding DNA sequences
Patent number
12,054,723
Issue date
Aug 6, 2024
BIONTECH SE
Florian Eberle
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Genome editing for treating glioblastoma
Patent number
12,049,625
Issue date
Jul 30, 2024
The Brigham & Women's Hospital, Inc.
Anna M. Krichevsky
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nanoparticles comprising protein-polynucleotide complexes and for d...
Patent number
12,036,287
Issue date
Jul 16, 2024
Asklepios Biopharmaceutical, Inc.
Gretchen M. Unger
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Base editing of PCSK9 and methods of using same for treatment of di...
Patent number
12,029,795
Issue date
Jul 9, 2024
Verve Therapeutics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method for stimulating axonal regeneration
Patent number
12,016,933
Issue date
Jun 25, 2024
The Hong Kong University of Science and Technology
Chao Yang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Gene editing for hemophilia A with improved factor VIII expression
Patent number
12,016,932
Issue date
Jun 25, 2024
CRISPR THERAPEUTICS AG
Alan Richard Brooks
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for treating inflammatory disease
Patent number
12,011,489
Issue date
Jun 18, 2024
Christopher Key
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Patents Applications
last 30 patents
Information
Patent Application
GENE EDITING FOR HEMOPHILIA A WITH IMPROVED FACTOR VIII EXPRESSION
Publication number
20240415981
Publication date
Dec 19, 2024
CRISPR Therapeutics AG
Alan Richard Brooks
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR UPREGULATING SHANK3 EXPRESSION
Publication number
20240408243
Publication date
Dec 12, 2024
Massachusetts Institute of Technology
Guoping Feng
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF SECRETED PROTEINS
Publication number
20240409597
Publication date
Dec 12, 2024
ModernaTX, Inc.
Antonin DE FOUGEROLLES
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS AND COMPOSITIONS FOR GENOME EDITING
Publication number
20240409961
Publication date
Dec 12, 2024
Salk Institute for Biological Studies
Juan Carlos IZPISUA BELMONTE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS TARGETING TRIM7
Publication number
20240401007
Publication date
Dec 5, 2024
The Board of Regents of the University of Texas System
John W. Schoggins
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Viral Vectors for Cancer Therapy
Publication number
20240398994
Publication date
Dec 5, 2024
Krystal Biotech, Inc.
Suma KRISHNAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SMALL MOLECULE-REGULATED GENE EXPRESSION SYSTEM
Publication number
20240398993
Publication date
Dec 5, 2024
Outpace Bio, Inc.
Glenna FOIGHT
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ADENO-ASSOCIATED VIRUS VECTORS FOR TREATMENT OF RETT SYNDROME
Publication number
20240392316
Publication date
Nov 28, 2024
Sarepta Therapeutics, Inc.
Colin O'Banion
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BASE EDITING OF PCSK9 AND METHODS OF USING SAME FOR TREATMENT OF DI...
Publication number
20240390523
Publication date
Nov 28, 2024
Verve Therapeutics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ADENO-ASSOCIATED VECTORS AND VIRIONS TO TREAT GALACTOSEMIA AND METH...
Publication number
20240390516
Publication date
Nov 28, 2024
Jaguar Gene Therapy, LLC
Michael Hughes
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR ALTERING GENE EXPRESSION FOR GENETIC DISORDERS
Publication number
20240392320
Publication date
Nov 28, 2024
BLUEALLELE CORPORATION
Nicholas J. Baltes
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNA CONSTRUCTS AND USES THEREOF
Publication number
20240390524
Publication date
Nov 28, 2024
BIONTECH SE
Ugur Sahin
B82 - NANO-TECHNOLOGY
Information
Patent Application
METHOD FOR TREATING A DISEASE
Publication number
20240384245
Publication date
Nov 21, 2024
SIRT6 LTD
Hagit ASHUSH
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MICROBIOTA ENGINEERING
Publication number
20240384279
Publication date
Nov 21, 2024
SNIPR Biome ApS
Christian MUNCK
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SYSTEMIC DELIVERY OF ADENO-ASSOCIATED VIRUS VECTOR EXPRESSING GAMMA...
Publication number
20240374684
Publication date
Nov 14, 2024
Sarepta Therapeutics, Inc.
Louise RODINO-KLAPAC
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR LIVER-SPECIFIC EXPRESSION OF FOLLISTATIN
Publication number
20240374760
Publication date
Nov 14, 2024
Oisin Biotechnologies, Inc.
Matthew Rein SCHOLZ
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
EFFECTOR PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF FOR MANUFA...
Publication number
20240366678
Publication date
Nov 7, 2024
MAMMOTH BIOSCIENCES, INC.
Mark Alan DEWITT
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TARGETING ONCOGENIC MUTATIONS WITH DUAL-CLEAVING ENDONUCLEASE
Publication number
20240360427
Publication date
Oct 31, 2024
SPECIFIC BIOLOGICS INC.
Brent E. STEAD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON...
Publication number
20240358736
Publication date
Oct 31, 2024
Avidity Biosciences, Inc.
Arthur A. LEVIN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR SWITCHING ANTIBIOTIC RESISTANCE MARKER...
Publication number
20240358008
Publication date
Oct 31, 2024
NEW YORK UNIVERSITY
Weimin ZHANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATMENT OF MUSCULAR DYSTROPHY
Publication number
20240350674
Publication date
Oct 24, 2024
Solid Biosciences Inc.
Kristy Jean Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CCL20 PROMOTER-REGULATED GENE EXPRESSION
Publication number
20240350675
Publication date
Oct 24, 2024
Lung Biotechnology PBC
Colin EXLINE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SYSTEMS AND METHODS FOR NUCLEIC ACID EXPRESSION IN VIVO
Publication number
20240350662
Publication date
Oct 24, 2024
DNARx
Robert James Debs
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY DISEASE
Publication number
20240325571
Publication date
Oct 3, 2024
Christopher Key
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS AND METHODS FOR RNA AFFINITY
Publication number
20240327847
Publication date
Oct 3, 2024
SANOFI
Jianping CUI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED...
Publication number
20240327476
Publication date
Oct 3, 2024
ModernaTX, Inc.
Antonin DE FOUGEROLLES
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
POLYRIBONUCLEOTIDES CONTAINING REDUCED URACIL CONTENT AND USES THEREOF
Publication number
20240318187
Publication date
Sep 26, 2024
ModernaTX, Inc.
Stephen G. HOGE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RECOMBINANT ADENO-ASSOCIATED VIRAL VECTORS FOR TREATING BIETTI CRYS...
Publication number
20240309068
Publication date
Sep 19, 2024
SHANGHAI VITALGEN BIOPHARMA CO., LTD.
Lu GUO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR ADMINISTERING OTOFERLIN DUAL VECTOR SY...
Publication number
20240309399
Publication date
Sep 19, 2024
Decibel Therapeutics, Inc.
Qi-Ying HU
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DNA COMPOSITIONS COMPRISING MODIFIED CYTOSINE
Publication number
20240293582
Publication date
Sep 5, 2024
Flagship Pioneering Innovations VII, LLC
Jacob Rosenblum Rubens
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE