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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
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C12N2310/323
modified ring structure
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Patents Grants
last 30 patents
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Patent Grant
Oligonucleotide agonists targeting progranulin
Patent number
12,203,071
Issue date
Jan 21, 2025
HOFFMANN-LA ROCHE INC.
Ravi Jagasia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for inhibiting gene expression of alpha-1...
Patent number
12,188,017
Issue date
Jan 7, 2025
Arrowhead Pharmaceuticals, Inc.
Christine I Wooddell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for reducing Ataxin-2 expression
Patent number
12,188,020
Issue date
Jan 7, 2025
Ionis Pharmaceuticals, Inc.
Frank Rigo
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for modulating ATXN1
Patent number
12,180,479
Issue date
Dec 31, 2024
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Dynamic pharmacokinetic-modifying anchors
Patent number
12,180,477
Issue date
Dec 31, 2024
UNIVERSITY OF MASSACHUSETTS
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compositions and methods for facilitating delivery of synthetic nuc...
Patent number
12,178,855
Issue date
Dec 31, 2024
Translate Bio MA, Inc.
Balkrishen Bhat
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides targeting alpha-synuclein and uses thereof
Patent number
12,180,478
Issue date
Dec 31, 2024
Bristol-Myers Squibb Company
Richard E. Olson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for improving strand biased
Patent number
12,173,287
Issue date
Dec 24, 2024
Alnylam Pharmaceuticals, Inc.
Rubina G. Parmar
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulators of APOL1 expression
Patent number
12,168,766
Issue date
Dec 17, 2024
Astrazeneca AB
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified double-stranded RNA agents
Patent number
12,168,767
Issue date
Dec 17, 2024
Alnylam Pharmaceuticals, Inc.
Martin Maier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Trimeric peptides for antisense delivery
Patent number
12,168,059
Issue date
Dec 17, 2024
Sarepta Therapeutics, Inc.
Justin Wolfe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compositions and methods for the treatment of expanded repeat-assoc...
Patent number
12,161,658
Issue date
Dec 10, 2024
UNIVERSITY OF MASSACHUSETTS
Joel D. Richter
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Gapmer antisense oligonucleotides targeting SARS-CoV-2 for treating...
Patent number
12,163,132
Issue date
Dec 10, 2024
Children's National Medical Center
Yi-Wen Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides to restore dysferlin protein expression...
Patent number
12,163,129
Issue date
Dec 10, 2024
University of Massachusetts
Robert H. Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotides for modulating Tau expression
Patent number
12,163,131
Issue date
Dec 10, 2024
HOFFMANN-LA ROCHE INC.
Peter Hagedorn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Modulating the cellular stress response
Patent number
12,157,888
Issue date
Dec 3, 2024
The General Hospital Corporation
Jeannie T. Lee
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Selective antisense compounds and uses thereof
Patent number
12,152,244
Issue date
Nov 26, 2024
Ionis Pharmaceuticals, Inc.
Michael Oestergaard
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Targeting human satellite II (HSATII)
Patent number
12,152,241
Issue date
Nov 26, 2024
The General Hospital Corporation
David T. Ting
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Treatment and diagnosis of inflammatory disorders
Patent number
12,146,138
Issue date
Nov 19, 2024
Zhenglun Zhu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Direct and selective inhibition of MDM4 for treatment of cancer
Patent number
12,139,712
Issue date
Nov 12, 2024
VIB VZW
Jean-Christophe Marine
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligomers and methods of using the same for treating dise...
Patent number
12,139,709
Issue date
Nov 12, 2024
Sarepta Therapeutics, Inc.
Frederick Joseph Schnell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compounds and methods for modulating UBE3A-ATS
Patent number
12,129,466
Issue date
Oct 29, 2024
Ionis Pharmaceuticals, Inc.
Paymaan Jafar-nejad
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified short interfering nucleic acid (siNA) molecules and uses t...
Patent number
12,129,469
Issue date
Oct 29, 2024
Aligos Therapeutics, Inc.
Leonid Beigelman
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Modified antisense oligomers for exon inclusion in spinal muscular...
Patent number
12,121,532
Issue date
Oct 22, 2024
Sarepta Therapeutics, Inc.
Marco A. Passini
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
GLP-1 receptor ligand moiety conjugated oligonucleotides and uses t...
Patent number
12,115,225
Issue date
Oct 15, 2024
Astrazeneca AB
Brett P. Monia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotides for modulating SCN9A expression
Patent number
12,116,576
Issue date
Oct 15, 2024
HOFFMANN-LA ROCHE INC.
Lykke Pedersen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Selective reduction of allelic variants
Patent number
12,110,491
Issue date
Oct 8, 2024
Ionis Pharmaceuticals, Inc.
C. Frank Bennett
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods of treating cancer having an active Wnt/β-catenin pathway
Patent number
12,109,212
Issue date
Oct 8, 2024
Dana-Farber Cancer Institute, Inc.
William C. Hahn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotide for targeting progranulin
Patent number
12,104,153
Issue date
Oct 1, 2024
HOFFMANN-LA ROCHE INC.
Ravi Jagasia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods of treating facioscapulohumeral muscular d...
Patent number
12,104,156
Issue date
Oct 1, 2024
AVIDITY BIOSCIENCES, INC.
Barbora Malecova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
DOSING OF MUSCLE TARGETING COMPLEXES FOR TREATING DYSTROPHINOPATHIES
Publication number
20250018050
Publication date
Jan 16, 2025
Dyne Therapeutics, Inc.
Cody A. Desjardins
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
IRNA COMPOSITIONS AND METHODS FOR SILENCING COMPLEMENT COMPONENT 3...
Publication number
20250019698
Publication date
Jan 16, 2025
Alnylam Pharmaceuticals, Inc.
Joseph Barry
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LACTATE DEHYDROGENASE A (LDHA) iRNA COMPOSITIONS AND METHODS OF USE...
Publication number
20250017953
Publication date
Jan 16, 2025
Alnylam Pharmaceuticals, Inc.
David Erbe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NEURODEGENERATIVE DISORDERS
Publication number
20250011772
Publication date
Jan 9, 2025
Teesside University
Pavlos Alifragis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DELIVERY OF ANITSENSE OLIGOMERS BY MIRROR IMAGE PEPTIDES
Publication number
20250011777
Publication date
Jan 9, 2025
Sarepta Therapeutics, Inc.
Carly K. SCHISSEL
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE COMPOUNDS AND METHODS FOR TARGETING CUG REPEATS
Publication number
20250011774
Publication date
Jan 9, 2025
Entrada Therapeutics, Inc.
Xiulong SHEN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR ENHANCING GENE SILENCING ACTIVITY OF O...
Publication number
20250011779
Publication date
Jan 9, 2025
Amgen Inc.
Jiamiao LU
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NUCLEIC ACID AGENTS FOR TREATMENT OF NON-SMALL-CELL LUNG CANCER
Publication number
20250002914
Publication date
Jan 2, 2025
University College Dublin
Rory JOHNSON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHOD OF TREATMENT FOR OPTIC ATROPHY
Publication number
20250002917
Publication date
Jan 2, 2025
PYC Therapeutics Limited
Janya Grainok
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Means and Methods for Chronic Wound Healing
Publication number
20240425857
Publication date
Dec 26, 2024
VIB VZW
Kodimangalam Ravichandran
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Pan-Genotypic Agents Against Influenza Virus and Methods of Using t...
Publication number
20240425852
Publication date
Dec 26, 2024
The Board of Trustees of the Leland Stanford Junior University
Jeffrey S. Glenn
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
NUCLEIC ACID-CONTROLLED CATALYTIC RNAS FOR TRIGGER-RESPONSIVE REGUL...
Publication number
20240425855
Publication date
Dec 26, 2024
HOFFMANN-LA ROCHE INC.
Simon AUSLAENDER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TIS-L TARGETING ANTIVIRAL ANTISENSE OLIGONUCLEOTIDE WITH ABILITY TO...
Publication number
20240417733
Publication date
Dec 19, 2024
Seoul National University R&DB Foundation
Daehyun BAEK
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ANTISENSE-INDUCED EXON EXCLUSION IN TYPE VII COLLAGEN
Publication number
20240415857
Publication date
Dec 19, 2024
Sarepta Therapeutics, Inc.
Dan V. Mourich
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR SKIPPING EXON 45 IN DUCHENNE MUSCULAR...
Publication number
20240417429
Publication date
Dec 19, 2024
Entrada Therapeutics, Inc.
Xiang Li
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMBINATION OF OLIGONUCLEOTIDES FOR MODULATING RTEL1 AND FUBP1
Publication number
20240409939
Publication date
Dec 12, 2024
HOFFMANN-LA ROCHE INC.
Konrad BLEICHER
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING NLRP3 OR NLRP1 EXPRESSION
Publication number
20240409931
Publication date
Dec 12, 2024
Molecular Axiom, LLC
Lishan CHEN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PREVENTIVE OR THERAPEUTIC AGENT FOR BENIGN ADULT FAMILIAL MYOCLONIC...
Publication number
20240409926
Publication date
Dec 12, 2024
RIKEN
Haruhisa INOUE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MODIFIED DOUBLE-STRANDED RNA AGENTS
Publication number
20240409942
Publication date
Dec 12, 2024
Alnylam Pharmaceuticals, Inc.
Martin MAIER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN C-III EXPRES...
Publication number
20240401038
Publication date
Dec 5, 2024
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
THERAPEUTICS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
Publication number
20240401036
Publication date
Dec 5, 2024
UCL Business LTD
Pietro Fratta
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
AGENTS USEFUL IN TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY
Publication number
20240401037
Publication date
Dec 5, 2024
Universite de Mons
Alexandra Belayew
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS OF TREATING CANCER HAVING AN ACTIVE WNT/BETA-CATENIN PATHWAY
Publication number
20240398804
Publication date
Dec 5, 2024
Dana-Farber Cancer Institute, Inc.
William C. HAHN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
BIOLOGICALLY STABLE XNAZYME THAT EFFICIENTLY SILENCES GENE EXPRESSI...
Publication number
20240392298
Publication date
Nov 28, 2024
The Regents of the University of California
John C. Chaput
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
COMPOSITIONS AND METHODS FOR MODULATING KRAS EXPRESSION
Publication number
20240392293
Publication date
Nov 28, 2024
Molecular Axiom, LLC
Lishan CHEN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATMENT OF MST1 RELATED DISEASES AND DISORDERS
Publication number
20240392295
Publication date
Nov 28, 2024
EMPIRICO INC.
Omri GOTTESMAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE
Publication number
20240390508
Publication date
Nov 28, 2024
Takeda Pharmaceutical Company Limited
Takatoshi YOGO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
ANGPTL4 OLIGONUCLEOTIDES INFLUENCING THE REGULATION OF THE FATTY AC...
Publication number
20240384272
Publication date
Nov 21, 2024
Lipigon Pharmaceuticals AB
Frank JASCHINSKI
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
Oligonucleotides
Publication number
20240384268
Publication date
Nov 21, 2024
Hudson Institute of Medical Research
Michael Paul Marie Gantier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
MUSCLE TARGETING COMPLEXES AND USES THEREOF FOR TREATING DYSTROPHIN...
Publication number
20240382609
Publication date
Nov 21, 2024
Dyne Therapeutics, Inc.
Cody A. Desjardins
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...