New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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C12N2710/16722

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CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N2710/00dsDNA Viruses

Current Industry

C12N2710/16722New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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Patents Grantslast 30 patents

Information Patent Grant
Recombinant varicella-zoster virus (VZV) vaccine
- Patent number 11,993,634
- Issue date May 28, 2024
- BEIJING LUZHU BIOTECHNOLOGY CO., LTD.
- Jian Kong
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Chimeric virus-like particles and uses thereof as antigen-specific...
- Patent number 11,944,677
- Issue date Apr 2, 2024
- VERIMMUNE INC.
- Joshua Weiyuan Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Varicella zoster virus (VZV) vaccine
- Patent number 11,918,644
- Issue date Mar 5, 2024
- ModernaTX, Inc.
- Giuseppe Ciaramella
- B82 - NANO-TECHNOLOGY
Information Patent Grant
BVP8 protein for killing Tetranychid mites and use thereof
- Patent number 11,793,204
- Issue date Oct 24, 2023
- Hubei Biopesticide Engineering Research Center
- Xiaoyan Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Nucleic acid vaccines for varicella zoster virus (VZV)
- Patent number 11,643,441
- Issue date May 9, 2023
- ModernaTX, Inc.
- Giuseppe Ciaramella
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antigen variant of Varicella Zoster virus and use thereof
- Patent number 11,642,408
- Issue date May 9, 2023
- MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
- Hyo Jung Nam
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antigen delivery platforms
- Patent number 11,639,370
- Issue date May 2, 2023
- GlaxoSmithKline Biologicals SA
- Michael Franti
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Non-neuroinvasive viruses and uses thereof
- Patent number 11,447,753
- Issue date Sep 20, 2022
- Northwestern University
- Gregory A. Smith
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Non-neuroinvasive viruses and uses thereof
- Patent number 11,339,378
- Issue date May 24, 2022
- Northwestern University
- Gregory A. Smith
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Recombinant virus with diminished latency and methods of using same
- Patent number 11,305,009
- Issue date Apr 19, 2022
- The United States of America, as represented by the Secretary, Department of...
- Jeffrey I. Cohen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Chimeric virus-like particles and uses thereof as antigen-specific...
- Patent number 11,285,203
- Issue date Mar 29, 2022
- VERIMMUNE INC.
- Joshua Weiyuan Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
ORF7 deficient varicella virus, vaccine comprising the virus and us...
- Patent number 11,220,673
- Issue date Jan 11, 2022
- Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.
- Hua Zhu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antigen delivery platforms
- Patent number 11,078,237
- Issue date Aug 3, 2021
- GlaxoSmithKline Biologicals SA
- Michael Franti
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Varicella zoster virus (VZV) vaccine
- Patent number 11,045,540
- Issue date Jun 29, 2021
- ModernaTX, Inc.
- Giuseppe Ciaramella
- B82 - NANO-TECHNOLOGY
Information Patent Grant
ORF7 deficient varicella virus, vaccine comprising the virus and us...
- Patent number 10,752,885
- Issue date Aug 25, 2020
- Rutgers, The State University of New Jersey
- Hua Zhu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Non-neuroinvasive viruses and uses thereof
- Patent number 10,647,964
- Issue date May 12, 2020
- Northwestern University
- Gregory A. Smith
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Subunit vaccine of porcine pseudorabies virus and preparation method
- Patent number 10,449,246
- Issue date Oct 22, 2019
- PULIKE BIOLOGICAL ENGINEERING, INC.
- Kegong Tian
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Conditionally replication deficient herpes virus and use thereof in...
- Patent number 10,232,035
- Issue date Mar 19, 2019
- The Regents of the University of Colorado, a Body Corporate
- Ravi Mahalingam
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Recombinant virus with diminished latency and methods of using same
- Patent number 10,166,285
- Issue date Jan 1, 2019
- The United States of America, as represented by the Secretary, Department of...
- Jeffrey I. Cohen
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Nucleic acid molecules encoding novel herpes antigens, vaccine comp...
- Patent number 9,994,619
- Issue date Jun 12, 2018
- The Trustees of the University of Pennsylvania
- David B Weiner
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
ORF7 deficient varicella virus, vaccine comprising the virus and us...
- Patent number 9,885,020
- Issue date Feb 6, 2018
- Rutgers, The State University of New Jersey
- Hua Zhu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Herpes simplex virus (HSV) with modified tropism, uses and process...
- Patent number 9,744,199
- Issue date Aug 29, 2017
- Alma Mater Studiorum—Università di Bologna
- Gabriella Campadelli
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Cattle reproductive disease vaccines
- Patent number 9,662,384
- Issue date May 30, 2017
- Zoetis Services LLC
- Paul Joseph Dominowski
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Porcine pseudorabies virus, vaccine composition and preparation met...
- Patent number 9,650,424
- Issue date May 16, 2017
- PULIKE BIOLOGICAL ENGINEERING, INC.
- Xuke Zhang
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Recombinant equine herpesvirus-1 vaccine containing mutated glycopr...
- Patent number 9,555,101
- Issue date Jan 31, 2017
- Merial, Inc.
- Jean Christophe Audonnet
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Newcastle disease virus vectored herpesvirus vaccines
- Patent number 9,446,118
- Issue date Sep 20, 2016
- Merial, Inc.
- Michel Bublot
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Herpes simplex virus (HSV) with modified tropism, uses and process...
- Patent number 9,157,071
- Issue date Oct 13, 2015
- Alma Mater Studiorum—Università di Bologna
- Gabriella Campadelli
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Newcastle disease virus vectored herpesvirus vaccines
- Patent number 8,986,706
- Issue date Mar 24, 2015
- Merial, Inc.
- Michel Bublot
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Recombinant equine herpesvirus-1 vaccine containing mutated glycopr...
- Patent number 8,916,371
- Issue date Dec 23, 2014
- Merial Limited
- Jean Christophe Audonnet
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Nucleic acid constructs
- Patent number 8,663,657
- Issue date Mar 4, 2014
- PowderJect Vaccines, Inc.
- James Fuller
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

Patents Applicationslast 30 patents

Information Patent Application
VARICELLA ZOSTER VIRUS (VZV) VACCINE
- Publication number 20250041407
- Publication date Feb 6, 2025
- ModernaTX, Inc.
- Giuseppe Ciaramella
- B82 - NANO-TECHNOLOGY
Information Patent Application
PSEUDORABIES VIRUS (PRV) EXPRESSING PORCINE CIRCOVIRUS 2 (PCV2) CAP...
- Publication number 20240398937
- Publication date Dec 5, 2024
- Zhejiang University
- Jiyong ZHOU
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CHIMERIC VIRUS-LIKE PARTICLES AND USES THEREOF AS ANTIGEN-SPECIFIC...
- Publication number 20240390473
- Publication date Nov 28, 2024
- VERIMMUNE INC.
- Joshua Weiyuan WANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PHARMACEUTICAL COMPOSITIONS FOR DELIVERY OF VIRAL ANTIGENS AND RELA...
- Publication number 20240366754
- Publication date Nov 7, 2024
- BIONTECH SE
- Richard B. Gaynor
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMPOSITIONS, METHODS, MODELS AND USES FOR SIMIAN VARICELLA VIRUS (...
- Publication number 20240091386
- Publication date Mar 21, 2024
- The Regents of the University of Colorado, a Body Corporate
- Ravi Mahalingam
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Genetically Modified Bovine Herpesvirus Type 1 (BHV-1) for use to T...
- Publication number 20230233630
- Publication date Jul 27, 2023
- McMaster University
- Karen Mossman
- C07 - ORGANIC CHEMISTRY
Information Patent Application
BVP8 PROTEIN FOR KILLING TETRANYCHID MITES AND USE THEREOF
- Publication number 20230011837
- Publication date Jan 12, 2023
- Hubei Biopesticide Engineering Research Center
- Xiaoyan LIU
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Application
VARICELLA ZOSTER VIRUS (VZV) VACCINE
- Publication number 20220409720
- Publication date Dec 29, 2022
- ModernaTX, Inc.
- Giuseppe Ciaramella
- B82 - NANO-TECHNOLOGY
Information Patent Application
RECOMBINANT NUCLEIC ACIDS CONTAINING ALPHAHERPESVIRUS PROMOTER SEQU...
- Publication number 20220378941
- Publication date Dec 1, 2022
- Esteban Engel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECOMBINANT VARICELLA-ZOSTER VIRUS (VZV) VACCINE
- Publication number 20220363721
- Publication date Nov 17, 2022
- Beijing Luzhu Biotechnology Co., Ltd
- Jian KONG
- C07 - ORGANIC CHEMISTRY
Information Patent Application
ANTIGEN VARIANT OF VARICELLA ZOSTER VIRUS AND USE THEREOF
- Publication number 20210187099
- Publication date Jun 24, 2021
- MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
- Hyo Jung NAM
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NON-NEUROINVASIVE VIRUSES AND USES THEREOF
- Publication number 20200263146
- Publication date Aug 20, 2020
- Northwestern University
- Gregory A. Smith
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Non-Neuroinvasive Viruses and Uses Thereof
- Publication number 20200263147
- Publication date Aug 20, 2020
- Northwestern University
- Gregory A. Smith
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
VARICELLA ZOSTER VIRUS (VZV) VACCINE
- Publication number 20200069793
- Publication date Mar 5, 2020
- ModernaTX, Inc.
- Giuseppe Ciaramella
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
ORF7 DEFICIENT VARICELLA VIRUS, VACCINE COMPRISING THE VIRUS AND US...
- Publication number 20180208905
- Publication date Jul 26, 2018
- Beijing Wantai Biological Pharmacy Enterprise Co., Ltd.
- Hua ZHU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Nucleic Acid Molecules Encoding Novel Herpes Antigens, Vaccine Comp...
- Publication number 20160130308
- Publication date May 12, 2016
- The Thustees of the University of Pennsylvania
- David B. Weiner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PORCINE PSEUDORABIES VIRUS, VACCINE COMPOSITION AND PREPARATION MET...
- Publication number 20160114029
- Publication date Apr 28, 2016
- PULIKE BIOLOGICAL ENGINEERING, INC.
- XUKE ZHANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NOVEL VARICELLA-ZOSTER VIRUS STRAINS, AND CHICKEN POX AND HERPES ZO...
- Publication number 20140147458
- Publication date May 29, 2014
- MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE
- Geun Hee Kim
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTIGEN DELIVERY PLATFORMS
- Publication number 20140030292
- Publication date Jan 30, 2014
- Novartis AG
- Michael Franti
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NUCLEIC ACID MOLECULES ENCODING NOVEL HERPES ANTIGENS, VACCINE COMP...
- Publication number 20140023673
- Publication date Jan 23, 2014
- David B Weiner
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ORF7 DEFICIENT VARICELLA VIRUS, VACCINE COMPRISING THE VIRUS AND US...
- Publication number 20130295124
- Publication date Nov 7, 2013
- New Jersey Medical School
- Hua Zhu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECOMBINANT EQUINE HERPESVIRUS-1 VACCINE CONTAINING MUTATED GLYCOPR...
- Publication number 20130251747
- Publication date Sep 26, 2013
- FREIE UNIVERSITAT BERLIN
- Jean Christophe Audonnet
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Recombinant Virus with Diminished Latency and Methods of Using Same
- Publication number 20130209506
- Publication date Aug 15, 2013
- THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the secreta...
- Jeffrey I. Cohen
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
CATTLE REPRODUCTIVE DISEASE VACCINES
- Publication number 20130129779
- Publication date May 23, 2013
- Paul Joseph Dominowski
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RECOMBINANT VARICELLA-ZOSTER VIRUS
- Publication number 20130101620
- Publication date Apr 25, 2013
- The Research Foundation for Microbial Diseases of Osaka University
- Kazuhiro Nagaike
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HERPES VIRUS BACKBONE FOR VIRAL VACCINE AND VACCINE BASED THEREON
- Publication number 20120156238
- Publication date Jun 21, 2012
- Saul J. Silverstein
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NEWCASTLE DISEASE VIRUS VECTORED HERPESVIRUS VACCINES
- Publication number 20120052089
- Publication date Mar 1, 2012
- Michel Bublot
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Bovine Herpes Virus-1 Compositions, Vaccines and Methods
- Publication number 20120034262
- Publication date Feb 9, 2012
- Novartis AG
- Nikolaus Osterrieder
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
HERPES SIMPLEX VIRUS (HSV) WITH MODIFIED TROPISM, USES AND PROCESS...
- Publication number 20110318268
- Publication date Dec 29, 2011
- Gabriella Campadelli
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Recombinant Varicella-Zoster Virus
- Publication number 20110189233
- Publication date Aug 4, 2011
- Kazuhiro Nagaike
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE

New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Recombinant varicella-zoster virus (VZV) vaccine

Chimeric virus-like particles and uses thereof as antigen-specific...

Varicella zoster virus (VZV) vaccine

BVP8 protein for killing Tetranychid mites and use thereof

Nucleic acid vaccines for varicella zoster virus (VZV)

Antigen variant of Varicella Zoster virus and use thereof

Antigen delivery platforms

Non-neuroinvasive viruses and uses thereof

Non-neuroinvasive viruses and uses thereof

Recombinant virus with diminished latency and methods of using same

Chimeric virus-like particles and uses thereof as antigen-specific...

ORF7 deficient varicella virus, vaccine comprising the virus and us...

Antigen delivery platforms

Varicella zoster virus (VZV) vaccine

ORF7 deficient varicella virus, vaccine comprising the virus and us...

Non-neuroinvasive viruses and uses thereof

Subunit vaccine of porcine pseudorabies virus and preparation method

Conditionally replication deficient herpes virus and use thereof in...

Recombinant virus with diminished latency and methods of using same

Nucleic acid molecules encoding novel herpes antigens, vaccine comp...

ORF7 deficient varicella virus, vaccine comprising the virus and us...

Herpes simplex virus (HSV) with modified tropism, uses and process...

Cattle reproductive disease vaccines

Porcine pseudorabies virus, vaccine composition and preparation met...

Recombinant equine herpesvirus-1 vaccine containing mutated glycopr...

Newcastle disease virus vectored herpesvirus vaccines

Herpes simplex virus (HSV) with modified tropism, uses and process...

Newcastle disease virus vectored herpesvirus vaccines

Recombinant equine herpesvirus-1 vaccine containing mutated glycopr...

Nucleic acid constructs

Patents Applicationslast 30 patents

VARICELLA ZOSTER VIRUS (VZV) VACCINE

PSEUDORABIES VIRUS (PRV) EXPRESSING PORCINE CIRCOVIRUS 2 (PCV2) CAP...

CHIMERIC VIRUS-LIKE PARTICLES AND USES THEREOF AS ANTIGEN-SPECIFIC...

PHARMACEUTICAL COMPOSITIONS FOR DELIVERY OF VIRAL ANTIGENS AND RELA...

COMPOSITIONS, METHODS, MODELS AND USES FOR SIMIAN VARICELLA VIRUS (...

Genetically Modified Bovine Herpesvirus Type 1 (BHV-1) for use to T...

BVP8 PROTEIN FOR KILLING TETRANYCHID MITES AND USE THEREOF

VARICELLA ZOSTER VIRUS (VZV) VACCINE

RECOMBINANT NUCLEIC ACIDS CONTAINING ALPHAHERPESVIRUS PROMOTER SEQU...

RECOMBINANT VARICELLA-ZOSTER VIRUS (VZV) VACCINE

ANTIGEN VARIANT OF VARICELLA ZOSTER VIRUS AND USE THEREOF

NON-NEUROINVASIVE VIRUSES AND USES THEREOF

Non-Neuroinvasive Viruses and Uses Thereof

VARICELLA ZOSTER VIRUS (VZV) VACCINE

ORF7 DEFICIENT VARICELLA VIRUS, VACCINE COMPRISING THE VIRUS AND US...

Nucleic Acid Molecules Encoding Novel Herpes Antigens, Vaccine Comp...

PORCINE PSEUDORABIES VIRUS, VACCINE COMPOSITION AND PREPARATION MET...

NOVEL VARICELLA-ZOSTER VIRUS STRAINS, AND CHICKEN POX AND HERPES ZO...

ANTIGEN DELIVERY PLATFORMS

NUCLEIC ACID MOLECULES ENCODING NOVEL HERPES ANTIGENS, VACCINE COMP...

ORF7 DEFICIENT VARICELLA VIRUS, VACCINE COMPRISING THE VIRUS AND US...

RECOMBINANT EQUINE HERPESVIRUS-1 VACCINE CONTAINING MUTATED GLYCOPR...

Recombinant Virus with Diminished Latency and Methods of Using Same

CATTLE REPRODUCTIVE DISEASE VACCINES

RECOMBINANT VARICELLA-ZOSTER VIRUS

HERPES VIRUS BACKBONE FOR VIRAL VACCINE AND VACCINE BASED THEREON

NEWCASTLE DISEASE VIRUS VECTORED HERPESVIRUS VACCINES

Bovine Herpes Virus-1 Compositions, Vaccines and Methods

HERPES SIMPLEX VIRUS (HSV) WITH MODIFIED TROPISM, USES AND PROCESS...

Recombinant Varicella-Zoster Virus