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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
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Patents Grants
last 30 patents
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Patent Grant
Compounds and methods for modulating SCN2A
Patent number
12,227,746
Issue date
Feb 18, 2025
Ionis Pharmaceuticals, Inc.
Paymaan Jafar-nejad
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Pharmaceutical composition for treatment of diseases associated wit...
Patent number
12,227,743
Issue date
Feb 18, 2025
Osaka University
Fumihiro Sanada
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for inhibiting expression of transthyretin
Patent number
12,227,744
Issue date
Feb 18, 2025
Alnylam Pharmaceuticals, Inc.
Dinah Wen-Yee Sah
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions, systems, and methods for regulation of hepatitis b vi...
Patent number
12,221,608
Issue date
Feb 11, 2025
TUNE THERAPEUTICS, INC.
Brian Cosgrove
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Acetylated ribonucleic acids and uses thereof
Patent number
12,215,317
Issue date
Feb 4, 2025
Helix Nanotechnologies Inc
Nikhil Dhar
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for RNA-directed target DNA modification a...
Patent number
12,215,343
Issue date
Feb 4, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense antibacterial compounds and methods
Patent number
12,209,240
Issue date
Jan 28, 2025
Board of Regents, The University of Texas System
David Greenberg
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotide agonists targeting progranulin
Patent number
12,203,071
Issue date
Jan 21, 2025
HOFFMANN-LA ROCHE INC.
Ravi Jagasia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CCR7 aptamers and uses thereof
Patent number
12,194,056
Issue date
Jan 14, 2025
City of Hope
John J. Rossi
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compositions and methods for inhibiting gene expression of alpha-1...
Patent number
12,188,017
Issue date
Jan 7, 2025
Arrowhead Pharmaceuticals, Inc.
Christine I Wooddell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for reducing Ataxin-2 expression
Patent number
12,188,020
Issue date
Jan 7, 2025
Ionis Pharmaceuticals, Inc.
Frank Rigo
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for modulating ATXN1
Patent number
12,180,479
Issue date
Dec 31, 2024
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides for the treatment of Stargardt disease
Patent number
12,180,471
Issue date
Dec 31, 2024
ProQR Therapeutics II B.V.
Aliye Seda Yilmaz-Elis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Dynamic pharmacokinetic-modifying anchors
Patent number
12,180,477
Issue date
Dec 31, 2024
UNIVERSITY OF MASSACHUSETTS
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for RNA-directed target DNA modification a...
Patent number
12,180,503
Issue date
Dec 31, 2024
The Regents of the University of California
Jennifer A. Doudna
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Methods and compositions for RNA-directed target DNA modification a...
Patent number
12,180,504
Issue date
Dec 31, 2024
The Regents of the University of California
Jennifer A. Doudna
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Compositions and methods for facilitating delivery of synthetic nuc...
Patent number
12,178,855
Issue date
Dec 31, 2024
Translate Bio MA, Inc.
Balkrishen Bhat
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides targeting alpha-synuclein and uses thereof
Patent number
12,180,478
Issue date
Dec 31, 2024
Bristol-Myers Squibb Company
Richard E. Olson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for improving strand biased
Patent number
12,173,287
Issue date
Dec 24, 2024
Alnylam Pharmaceuticals, Inc.
Rubina G. Parmar
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA-editing oligonucleotides and uses thereof
Patent number
12,173,285
Issue date
Dec 24, 2024
Korro Bio, Inc.
Andrew W. Fraley
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Fully stabilized asymmetric siRNA
Patent number
12,173,286
Issue date
Dec 24, 2024
UNIVERSITY OF MASSACHUSETTS
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulators of APOL1 expression
Patent number
12,168,766
Issue date
Dec 17, 2024
Astrazeneca AB
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified double-stranded RNA agents
Patent number
12,168,767
Issue date
Dec 17, 2024
Alnylam Pharmaceuticals, Inc.
Martin Maier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Trimeric peptides for antisense delivery
Patent number
12,168,059
Issue date
Dec 17, 2024
Sarepta Therapeutics, Inc.
Justin Wolfe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR-CAS9 modified CD34+ human hematopoietic stem and progenitor...
Patent number
12,161,674
Issue date
Dec 10, 2024
Vertex Pharmaceuticals Incorporated
Ewelina Morawa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for the treatment of expanded repeat-assoc...
Patent number
12,161,658
Issue date
Dec 10, 2024
UNIVERSITY OF MASSACHUSETTS
Joel D. Richter
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Gapmer antisense oligonucleotides targeting SARS-CoV-2 for treating...
Patent number
12,163,132
Issue date
Dec 10, 2024
Children's National Medical Center
Yi-Wen Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides to restore dysferlin protein expression...
Patent number
12,163,129
Issue date
Dec 10, 2024
University of Massachusetts
Robert H. Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modulating neuronal excitability and m...
Patent number
12,163,130
Issue date
Dec 10, 2024
Icahn School of Medicine at Mount Sinai
Anne Schaefer
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Grant
Oligonucleotides for modulating Tau expression
Patent number
12,163,131
Issue date
Dec 10, 2024
HOFFMANN-LA ROCHE INC.
Peter Hagedorn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
TUNABLE REVERSIR TM COMPOUNDS
Publication number
20250059536
Publication date
Feb 20, 2025
Alnylam Pharmaceuticals, Inc.
Ivan ZLATEV
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SGLT-2 TARGETING OLIGONUCLEOTIDES
Publication number
20250059539
Publication date
Feb 20, 2025
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NLRP3 oligonucleotide for use in preventing and/or treating an infl...
Publication number
20250059547
Publication date
Feb 20, 2025
Secarna Pharmaceuticals GmbH & Co KG
Marta Lucia DE LOS REYES
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
THERAPEUTIC OLIGONUCLEOTIDES HAVING AN INTER-NUCLEOSIDE AMIDE LINKAGE
Publication number
20250059537
Publication date
Feb 20, 2025
Oxford University Innovation Limited
Tom BROWN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING NUCLEIC ACID, PR...
Publication number
20250057870
Publication date
Feb 20, 2025
SUZHOU RIBO LIFE SCIENCE CO., LTD
Zicai LIANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDES (ASO) FOR EFFICIENT AND PRECISE RNA EDIT...
Publication number
20250059534
Publication date
Feb 20, 2025
Eberhard-Karls-Universitat Tubingen
Thorsten STAFFORST
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SNCA-TARGETING SIRNA COMPOSITIONS FOR TREATING SNCA-ASSOCIATED DISEASE
Publication number
20250059541
Publication date
Feb 20, 2025
Alnylam Pharmaceuticals, Inc.
Lan Thi Hoang Dang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CELL DEATH-INDUCING DFFA-LIKE EFFECTOR B (CIDEB) IRNA COMPOSITIONS...
Publication number
20250059542
Publication date
Feb 20, 2025
Alnylam Pharmaceuticals, Inc.
JEFFREY ZUBER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDES (ASOS) THAT SUPPRESS SARS-COV-2 REPLICATION
Publication number
20250059544
Publication date
Feb 20, 2025
The Children's Medical Center Corporation
Hao Wu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250051765
Publication date
Feb 13, 2025
Alnylam Pharmaceuticals, Inc.
Kevin FITZGERALD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
iRNA Compositions and Methods for Silencing MYLIP
Publication number
20250051767
Publication date
Feb 13, 2025
Alnylam Pharmaceuticals, Inc.
LUCAS WARD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Antisense Oligonucleotide for Targeting Progranulin
Publication number
20250051772
Publication date
Feb 13, 2025
HOFFMANN-LA ROCHE INC.
Ravi Jagasia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
INHIBIN SUBUNIT BETA E (INHBE) MODULATOR COMPOSITIONS AND METHODS O...
Publication number
20250051779
Publication date
Feb 13, 2025
Alnylam Pharmaceuticals, Inc.
Aimee M. Deaton
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDE TARGETING ATN1 MRNA OR PRE-MRNA
Publication number
20250051769
Publication date
Feb 13, 2025
Nippon Shinyaku Co., Ltd.
Takao KAWANO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING mRNA SPLICING
Publication number
20250051780
Publication date
Feb 13, 2025
Entrada Therapeutics, Inc.
Ziqing QIAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATMENT OF NEUROLOGICAL DISEASES USING MODULATORS OF UNC13A GENE...
Publication number
20250051766
Publication date
Feb 13, 2025
QURALIS CORPORATION
SANDRA HINCKLEY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
THERAPEUTICS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
Publication number
20250051775
Publication date
Feb 13, 2025
The United States of America, as represented by the Secretary, Department of...
Pietro Fratta
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS OF MODULATING LONG NONCODING TRANSCRIPTS A...
Publication number
20250051776
Publication date
Feb 13, 2025
HAYA Therapeutics SA
Samir OUNZAIN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING INTERFERON REGULATORY FACTO...
Publication number
20250051393
Publication date
Feb 13, 2025
Entrada Therapeutics, Inc.
Ziqing QIAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Antisense Compounds Targeting Genes Associated with Cystic Fibrosis
Publication number
20250049838
Publication date
Feb 13, 2025
ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE
Michelle L. Hastings
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information
Patent Application
COMPOSITIONS COMPRISING THERAPEUTIC NUCLEIC ACID AND SAPONIN FOR TH...
Publication number
20250051770
Publication date
Feb 13, 2025
Sapreme Technologies B.V.
Miriam Verena BUJNY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDES FOR MODULATING TAU EXPRESSION
Publication number
20250051777
Publication date
Feb 13, 2025
HOFFMANN-LA ROCHE INC.
Peter HAGEDORN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS VIA...
Publication number
20250043283
Publication date
Feb 6, 2025
Sarepta Therapeutics, Inc.
Kyle A. Totaro
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CRISPR-CAS9 Modified CD34+ Human Hematopoietic Stem and Progenitor...
Publication number
20250041349
Publication date
Feb 6, 2025
VERTEX PHARMACEUTICALS INCORPORATED
Ewelina Morawa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS FOR INHIBITING DETOXIFICATION RESPONSE
Publication number
20250043286
Publication date
Feb 6, 2025
The General Hospital Corporation
Gary Ruvkun
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATMENT OF FGG RELATED DISEASES AND DISORDERS
Publication number
20250043281
Publication date
Feb 6, 2025
EMPIRICO INC.
Omri GOTTESMAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PRODUCTS AND COMPOSITIONS
Publication number
20250043288
Publication date
Feb 6, 2025
Silence Therapeutics GMBH
Judith HAUPTMANN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
3-HYDROXY-3-METHYLGLUTARYL-COA REDUCTASE (HMGCR) IRNA COMPOSITIONS...
Publication number
20250043289
Publication date
Feb 6, 2025
Alnylam Pharmaceuticals, Inc.
Ho-Chou Tu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDES FOR SNCA MODULATION
Publication number
20250043284
Publication date
Feb 6, 2025
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE NUCLEIC ACIDS
Publication number
20250042933
Publication date
Feb 6, 2025
NIPPON SHINYAKU CO., LTD
Naoki Watanabe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...