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C12N2310/315
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C12
Biochemistry
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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N2310/00
Structure or type of the nucleic acid
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C12N2310/315
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Patents Grants
last 30 patents
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Patent Grant
FN3 domain-siRNA conjugates and uses thereof
Patent number
12,239,710
Issue date
Mar 4, 2025
ARO BIOTHERAPEUTICS COMPANY
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
REVERSIR™ compounds
Patent number
12,241,064
Issue date
Mar 4, 2025
Alnylam Pharmaceuticals, Inc.
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for reducing LRRK2 expression
Patent number
12,241,067
Issue date
Mar 4, 2025
Ionis Pharmaceuticals, Inc.
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Therapeutic oligonucleotides
Patent number
12,234,455
Issue date
Feb 25, 2025
IFOM Fondazione Istituto FIRC di Oncologia Molecolare
Fabrizio d′Adda di Fagagna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nucleic acid-polypeptide compositions and uses thereof
Patent number
12,234,290
Issue date
Feb 25, 2025
AVIDITY BIOSCIENCES, INC.
Andrew John Geall
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified compounds and uses thereof
Patent number
12,234,447
Issue date
Feb 25, 2025
Ionis Pharmaceuticals, Inc.
Punit P. Seth
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modulating APOC3 expression
Patent number
12,234,456
Issue date
Feb 25, 2025
Dicerna Pharmaceuticals, Inc.
Bob Dale Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and compositions including phosphorothioated oligodeoxynu...
Patent number
12,227,745
Issue date
Feb 18, 2025
City of Hope
Marcin Tomasz Kortylewski
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for modulating SCN2A
Patent number
12,227,746
Issue date
Feb 18, 2025
Ionis Pharmaceuticals, Inc.
Paymaan Jafar-nejad
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for inhibiting expression of transthyretin
Patent number
12,227,744
Issue date
Feb 18, 2025
Alnylam Pharmaceuticals, Inc.
Dinah Wen-Yee Sah
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions, systems, and methods for regulation of hepatitis b vi...
Patent number
12,221,608
Issue date
Feb 11, 2025
TUNE THERAPEUTICS, INC.
Brian Cosgrove
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulators of diacyglycerol acyltransferase 2 (DGAT2)
Patent number
12,215,321
Issue date
Feb 4, 2025
Ionis Pharmaceuticals, Inc.
Eric E. Swayze
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Multiplexed analysis of materials for tissue delivery
Patent number
12,201,696
Issue date
Jan 21, 2025
Georgia Tech Research Corporation
James Dahlman
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Oligonucleotide agonists targeting progranulin
Patent number
12,203,071
Issue date
Jan 21, 2025
HOFFMANN-LA ROCHE INC.
Ravi Jagasia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for inhibiting gene expression of alpha-1...
Patent number
12,188,017
Issue date
Jan 7, 2025
Arrowhead Pharmaceuticals, Inc.
Christine I Wooddell
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods for reducing Ataxin-2 expression
Patent number
12,188,020
Issue date
Jan 7, 2025
Ionis Pharmaceuticals, Inc.
Frank Rigo
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides for the treatment of Stargardt disease
Patent number
12,180,471
Issue date
Dec 31, 2024
ProQR Therapeutics II B.V.
Aliye Seda Yilmaz-Elis
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and methods for modulating ATXN1
Patent number
12,180,479
Issue date
Dec 31, 2024
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Chiral design
Patent number
12,180,472
Issue date
Dec 31, 2024
WAVE LIFE SCIENCES LTD.
Meena Meena
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Dynamic pharmacokinetic-modifying anchors
Patent number
12,180,477
Issue date
Dec 31, 2024
UNIVERSITY OF MASSACHUSETTS
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides targeting alpha-synuclein and uses thereof
Patent number
12,180,478
Issue date
Dec 31, 2024
Bristol-Myers Squibb Company
Richard E. Olson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for improving strand biased
Patent number
12,173,287
Issue date
Dec 24, 2024
Alnylam Pharmaceuticals, Inc.
Rubina G. Parmar
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA-editing oligonucleotides and uses thereof
Patent number
12,173,285
Issue date
Dec 24, 2024
Korro Bio, Inc.
Andrew W. Fraley
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Fully stabilized asymmetric siRNA
Patent number
12,173,286
Issue date
Dec 24, 2024
UNIVERSITY OF MASSACHUSETTS
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modified guide RNAs
Patent number
12,173,284
Issue date
Dec 24, 2024
Intellia Therapeutics, Inc.
Amy Madison Rhoden Smith
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulators of APOL1 expression
Patent number
12,168,766
Issue date
Dec 17, 2024
Astrazeneca AB
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
CRISPR-CAS9 modified CD34+ human hematopoietic stem and progenitor...
Patent number
12,161,674
Issue date
Dec 10, 2024
Vertex Pharmaceuticals Incorporated
Ewelina Morawa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Gapmer antisense oligonucleotides targeting SARS-CoV-2 for treating...
Patent number
12,163,132
Issue date
Dec 10, 2024
Children's National Medical Center
Yi-Wen Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides to restore dysferlin protein expression...
Patent number
12,163,129
Issue date
Dec 10, 2024
University of Massachusetts
Robert H. Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modulating neuronal excitability and m...
Patent number
12,163,130
Issue date
Dec 10, 2024
Icahn School of Medicine at Mount Sinai
Anne Schaefer
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Patents Applications
last 30 patents
Information
Patent Application
RNA INTERFERENCE MEDIATED INHIBITION OF PROLYL HYDROXYLASE DOMAIN 2...
Publication number
20250066791
Publication date
Feb 27, 2025
SIRNA THERAPEUTICS, INC.
Brandon Ason
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR INHIBITION OF HAO1 (HYDROXYACID OXIDAS...
Publication number
20250064936
Publication date
Feb 27, 2025
Alnylam Pharmaceuticals, Inc.
William Querbes
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNA-EDITING OLIGONUCLEOTIDES AND USES THEREOF
Publication number
20250066773
Publication date
Feb 27, 2025
Korro Bio, Inc.
Andrew W. FRALEY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOUNDS AND METHODS FOR MODULATION OF DYSTROPHIA MYOTONICA-PROTEI...
Publication number
20250066792
Publication date
Feb 27, 2025
Ionis Pharmaceuticals, Inc.
Eric E. Swayze
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDES WITH INTERNUCLEOTIDE LINKAGE MODIFICATIONS FOR KID...
Publication number
20250066780
Publication date
Feb 27, 2025
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGOMERS FOR TREATMENT OF CHRONIC KIDNEY DISEASE
Publication number
20250066776
Publication date
Feb 27, 2025
Sarepta Therapeutics, Inc.
Ryan OLIVER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ADVANCED RNA TARGETING (ARNATAR) FOR ANGIOTENSINOGEN
Publication number
20250066779
Publication date
Feb 27, 2025
Arnatar Therapeutics, Inc
Yen Lieu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
THERAPEUTIC OLIGONUCLEOTIDES
Publication number
20250066784
Publication date
Feb 27, 2025
IFOM - Fondazione Istituto FIRC di Oncologia Molecolare
Fabrizio d'Adda di Fagagna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MODULATORS OF APOL1 EXPRESSION
Publication number
20250066785
Publication date
Feb 27, 2025
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Application of PRDX5 and GPX4 Genes in Preparation of Drugs for Cas...
Publication number
20250066794
Publication date
Feb 27, 2025
JIANGNAN UNIVERSITY
Rong WANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF
Publication number
20250066775
Publication date
Feb 27, 2025
WAVE LIFE SCIENCES LTD.
Chandra Vargeese
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND AGENTS FOR INCREASING RBM3 EXPRESSION
Publication number
20250066777
Publication date
Feb 27, 2025
FREIE UNIVERSITAT BERLIN
Marco PREUßNER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
AMYLOID PRECURSOR PROTEIN (APP) RNAi AGENTS
Publication number
20250064958
Publication date
Feb 27, 2025
Eli Lilly and Company
Riazul ALAM
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Modified Guide RNAs
Publication number
20250059532
Publication date
Feb 20, 2025
INTELLIA THERAPEUTICS, INC.
Amy Madison Rhoden Smith
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TUNABLE REVERSIR TM COMPOUNDS
Publication number
20250059536
Publication date
Feb 20, 2025
Alnylam Pharmaceuticals, Inc.
Ivan ZLATEV
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SGLT-2 TARGETING OLIGONUCLEOTIDES
Publication number
20250059539
Publication date
Feb 20, 2025
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
THERAPEUTIC OLIGONUCLEOTIDES HAVING AN INTER-NUCLEOSIDE AMIDE LINKAGE
Publication number
20250059537
Publication date
Feb 20, 2025
Oxford University Innovation Limited
Tom BROWN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING NUCLEIC ACID, PR...
Publication number
20250057870
Publication date
Feb 20, 2025
SUZHOU RIBO LIFE SCIENCE CO., LTD
Zicai LIANG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDES (ASO) FOR EFFICIENT AND PRECISE RNA EDIT...
Publication number
20250059534
Publication date
Feb 20, 2025
Eberhard-Karls-Universitat Tubingen
Thorsten STAFFORST
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SNCA-TARGETING SIRNA COMPOSITIONS FOR TREATING SNCA-ASSOCIATED DISEASE
Publication number
20250059541
Publication date
Feb 20, 2025
Alnylam Pharmaceuticals, Inc.
Lan Thi Hoang Dang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CELL DEATH-INDUCING DFFA-LIKE EFFECTOR B (CIDEB) IRNA COMPOSITIONS...
Publication number
20250059542
Publication date
Feb 20, 2025
Alnylam Pharmaceuticals, Inc.
JEFFREY ZUBER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250051765
Publication date
Feb 13, 2025
Alnylam Pharmaceuticals, Inc.
Kevin FITZGERALD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Antisense Oligonucleotide for Targeting Progranulin
Publication number
20250051772
Publication date
Feb 13, 2025
HOFFMANN-LA ROCHE INC.
Ravi Jagasia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDE TARGETING ATN1 MRNA OR PRE-MRNA
Publication number
20250051769
Publication date
Feb 13, 2025
Nippon Shinyaku Co., Ltd.
Takao KAWANO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250051778
Publication date
Feb 13, 2025
WAVE LIFE SCIENCES LTD.
Michael John Byrne
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATMENT OF NEUROLOGICAL DISEASES USING MODULATORS OF UNC13A GENE...
Publication number
20250051766
Publication date
Feb 13, 2025
QURALIS CORPORATION
SANDRA HINCKLEY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
THERAPEUTICS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
Publication number
20250051775
Publication date
Feb 13, 2025
The United States of America, as represented by the Secretary, Department of...
Pietro Fratta
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOUNDS AND METHODS FOR MODULATING GLYCOGEN SYNTHASE 1
Publication number
20250051781
Publication date
Feb 13, 2025
Ionis Pharmaceuticals, Inc.
Huynh-Hoa Bui
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS COMPRISING THERAPEUTIC NUCLEIC ACID AND SAPONIN FOR TH...
Publication number
20250051770
Publication date
Feb 13, 2025
Sapreme Technologies B.V.
Miriam Verena BUJNY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDES FOR MODULATING TAU EXPRESSION
Publication number
20250051777
Publication date
Feb 13, 2025
HOFFMANN-LA ROCHE INC.
Peter HAGEDORN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...